Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy

Immunity

Volumn 35, Issue 5, 2011, Pages 746-756

  O'Neill, Shannon K ^a   Getahun, Andrew ^a   Gauld, Stephen B ^a   Merrell, Kevin T ^a   Tamir, Idan ^a   Smith, Mia J ^a   Dal Porto, Joseph M ^a   Li, Quan Zhen ^b   Cambier, John C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADAPTOR PROTEIN; CD79A ANTIGEN; CD79B ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PHOSPHOTRANSFERASE; PROTEIN DOWNSTREAM OF KINASE 1; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CLONAL ANERGY; CONTROLLED STUDY; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; LUPUS LIKE SYNDROME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION;

AMINO ACID MOTIFS; ANIMALS; ANTIGENS, CD79; AUTOIMMUNITY; B-LYMPHOCYTES; CELL LINE, TUMOR; CELLS, CULTURED; CLONAL ANERGY; DNA-BINDING PROTEINS; GENE TARGETING; MICE; MICE, TRANSGENIC; PHOSPHOPROTEINS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TYROSINE;

EID: 81955161811     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.10.011     Document Type: Article

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