TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses

Molecular Immunology

Volumn 45, Issue 11, 2008, Pages 3074-3084

  Arimura, Yutaka ^a,b   Vang, Torkel ^a   Tautz, Lutz ^a   Williams, Scott ^a   Mustelin, Tomas ^a,c  

^a BURNHAM INSTITUTE   (United States)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c AMGEN INC   (United States)

Author keywords

Lck; Protein tyrosine phosphatase (PTP); PTP PEST; PTPN12; T cell activation

Indexed keywords

CD28 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE PHOSPHATASE; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TRANSACTIVATION;

ANIMALS; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMMUNOLOGIC MEMORY; JURKAT CELLS; LEUKEMIA; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 12; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANS-ACTIVATION (GENETICS);

EID: 43449128867     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.03.019     Document Type: Article

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