A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: Aberrant development and enhanced function of B lymphocytes in SHIP(-/-) mice

Journal of Experimental Medicine

Volumn 191, Issue 5, 2000, Pages 781-794

  Helgason, Cheryl D ^a   Kalberer, Christian P ^a   Damen, Jacqueline E ^a   Chappel, Suzanne M ^a   Pineault, Nicolas ^a   Krystal, Gerald ^a,b   Humphries, R Keith ^a,c,d  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b Department of Pathology and Laboratory Medicine ^*  (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Antigen response; B cell receptor; Fc RIIB; Immunoglobulin; Signal transduction

Indexed keywords

B LYMPHOCYTE RECEPTOR; FC RECEPTOR; FICOLL; IMMUNOGLOBULIN G; IMMUNOMODULATING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; SRC HOMOLOGY 2 DOMAIN CONTAINING INOSITOL 5 PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOREACTIVITY; IMMUNOSTIMULATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE TRANSFER; MITOSIS RATE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING;

EID: 0034610982     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.5.781     Document Type: Article

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