PTPα activates Lyn and Fyn and suppresses Hck to negatively regulate FcεRI-dependent mast cell activation and allergic responses

Journal of Immunology

Volumn 185, Issue 10, 2010, Pages 5993-6002

  Samayawardhena, Lionel A ^a   Pallen, Catherine J ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEMATOPOIETIC CELL KINASE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN FC FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE ALPHA; PEPTIDOLEUKOTRIENE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE FYN; PROTEIN KINASE LYN; SHIP PROTEIN; UNCLASSIFIED DRUG; FYN PROTEIN, MOUSE; HCK PROTEIN, MOUSE; IMMUNOGLOBULIN E RECEPTOR; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE; PTPRA PROTEIN, MOUSE; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE;

ALLERGY; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; DEGRANULATION; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; MOUSE MUTANT;

ANIMALS; CELL DEGRANULATION; HYPERSENSITIVITY; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-FYN; PROTO-ONCOGENE PROTEINS C-HCK; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 4; RECEPTORS, IGE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 78650672157     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1001261     Document Type: Article

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