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Volumn 191, Issue 9, 2000, Pages 1545-1554

Differential regulation of B cell development, activation, and death by the Src homology 2 domain-containing 5' inositol phosphatase (SHIP)

Author keywords

Antigen; BCR; Phosphatidylinositol 3,4,5 triphosphate; Phosphatidylinositol 3 kinase; Signal transduction

Indexed keywords

B LYMPHOCYTE RECEPTOR; FC RECEPTOR; INOSITOL PHOSPHATE; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE;

EID: 0034194516     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.9.1545     Document Type: Article
Times cited : (115)

References (65)
  • 1
    • 0033118746 scopus 로고    scopus 로고
    • B cell development: Signal transduction by antigen receptors and their surrogates
    • Benschop, R.J., and J.C. Cambier. 1999. B cell development: signal transduction by antigen receptors and their surrogates. Curr. Opin. Immunol. 11:143-151.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 143-151
    • Benschop, R.J.1    Cambier, J.C.2
  • 2
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam, K.P., R. Kuhn, and K. Rajewsky. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell. 90:1073-1083.
    • (1997) Cell. , vol.90 , pp. 1073-1083
    • Lam, K.P.1    Kuhn, R.2    Rajewsky, K.3
  • 3
    • 0025852445 scopus 로고
    • A b cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura, D., J. Roes, R. Kuhn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature. 350:423-426.
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kuhn, R.3    Rajewsky, K.4
  • 5
    • 0029913115 scopus 로고    scopus 로고
    • Regulation of an early developmental checkpoint in the B cell pathway by Ig beta
    • Gong, S., and M.C. Nussenzweig. 1996. Regulation of an early developmental checkpoint in the B cell pathway by Ig beta. Science. 272:411-414.
    • (1996) Science , vol.272 , pp. 411-414
    • Gong, S.1    Nussenzweig, M.C.2
  • 6
    • 0030058466 scopus 로고    scopus 로고
    • Aberrant B cell development and immune response in mice with a compromised bcr complex
    • Torres, R.M., H. Flaswinkel, M. Reth, and K. Rajewsky. 1996. Aberrant B cell development and immune response in mice with a compromised BCR complex. Science. 272:1804-1808.
    • (1996) Science , vol.272 , pp. 1804-1808
    • Torres, R.M.1    Flaswinkel, H.2    Reth, M.3    Rajewsky, K.4
  • 8
    • 0028783322 scopus 로고
    • Syk tyrosine kinase required for mouse viability and B-cell development
    • Cheng, A.M., B. Rowley, W. Pao, A. Hayday, J.B. Bolen, and T. Pawson. 1995. Syk tyrosine kinase required for mouse viability and B-cell development. Nature. 378:303-306.
    • (1995) Nature , vol.378 , pp. 303-306
    • Cheng, A.M.1    Rowley, B.2    Pao, W.3    Hayday, A.4    Bolen, J.B.5    Pawson, T.6
  • 9
    • 0033556333 scopus 로고    scopus 로고
    • Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha
    • Fruman, D.A., S.B. Snapper, C.M. Yballe, L. Davidson, J.Y. Yu, F.W. Alt, and L.C. Cantley. 1999. Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha. Science. 283:393-397.
    • (1999) Science , vol.283 , pp. 393-397
    • Fruman, D.A.1    Snapper, S.B.2    Yballe, C.M.3    Davidson, L.4    Yu, J.Y.5    Alt, F.W.6    Cantley, L.C.7
  • 10
    • 0033555829 scopus 로고    scopus 로고
    • Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase
    • Suzuki, H., Y. Terauchi, M. Fujiwara, S. Aizawa, Y. Yazaki, T. Kadowaki, and S. Koyasu. 1999. Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. Science. 283:390-392.
    • (1999) Science , vol.283 , pp. 390-392
    • Suzuki, H.1    Terauchi, Y.2    Fujiwara, M.3    Aizawa, S.4    Yazaki, Y.5    Kadowaki, T.6    Koyasu, S.7
  • 12
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • DeFranco, A.L. 1997. The complexity of signaling pathways activated by the BCR. Curr. Opin. Immunol. 9:296-308.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 296-308
    • DeFranco, A.L.1
  • 13
    • 0032541653 scopus 로고    scopus 로고
    • Antigen receptor signaling: Integration of protein tyrosine kinase functions
    • Tamir, I., and J.C. Cambier. 1998. Antigen receptor signaling: integration of protein tyrosine kinase functions. Oncogene. 17:1353-1364.
    • (1998) Oncogene , vol.17 , pp. 1353-1364
    • Tamir, I.1    Cambier, J.C.2
  • 14
    • 0027169534 scopus 로고
    • CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase
    • Tuveson, D.A., R.H. Carter, S.P. Soltoff and D.T. Fearon. 1993. CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase. Science. 260:986-989.
    • (1993) Science , vol.260 , pp. 986-989
    • Tuveson, D.A.1    Carter, R.H.2    Soltoff, S.P.3    Fearon, D.T.4
  • 16
    • 0033561627 scopus 로고    scopus 로고
    • Phosphorylation of CD19 Y484 and Y515, and linked activation of phosphatidylinositol 3-kinase, are required for B cell antigen receptor-mediated activation of Bruton's tyrosine kinase
    • Buhl, A.M., and J.C. Cambier. 1999. Phosphorylation of CD19 Y484 and Y515, and linked activation of phosphatidylinositol 3-kinase, are required for B cell antigen receptor-mediated activation of Bruton's tyrosine kinase. J. Immunol. 162:4438-4446.
    • (1999) J. Immunol. , vol.162 , pp. 4438-4446
    • Buhl, A.M.1    Cambier, J.C.2
  • 17
    • 0032055485 scopus 로고    scopus 로고
    • SHIP modulates immune receptor responses by regulating membrane association of Btk
    • Bolland, S., R.N. Pearse, T. Kurosaki, and J.V. Ravetch. 1998. SHIP modulates immune receptor responses by regulating membrane association of Btk. Immunity. 8:509-516.
    • (1998) Immunity , vol.8 , pp. 509-516
    • Bolland, S.1    Pearse, R.N.2    Kurosaki, T.3    Ravetch, J.V.4
  • 20
    • 0033566911 scopus 로고    scopus 로고
    • The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase
    • Gold, M.R., M.P. Scheid, L. Santos, M. Dang-Lawson, R.A. Roth, L. Matusuuchi, V. Duronio, and D.L. Krebs. 1999. The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase. J. Immunol. 163:1894-1905.
    • (1999) J. Immunol. , vol.163 , pp. 1894-1905
    • Gold, M.R.1    Scheid, M.P.2    Santos, L.3    Dang-Lawson, M.4    Roth, R.A.5    Matusuuchi, L.6    Duronio, V.7    Krebs, D.L.8
  • 21
  • 22
    • 0033531796 scopus 로고    scopus 로고
    • FcgammaRIIb modulation of surface immunoglobulin-induced akt activation in murine B cells
    • Jacob, A., D. Cooney, S. Tridandapani, T. Kelley, and K.M. Coggeshall. 1999. FcgammaRIIb modulation of surface immunoglobulin-induced akt activation in murine B cells J. Biol. Chem. 274:13704-13710.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13704-13710
    • Jacob, A.1    Cooney, D.2    Tridandapani, S.3    Kelley, T.4    Coggeshall, K.M.5
  • 23
    • 0033025948 scopus 로고    scopus 로고
    • Signal transduction from the B cell antigen-receptor
    • Campbell, K.S. 1999. Signal transduction from the B cell antigen-receptor. Curr. Opin. Immunol. 11:256-264.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 256-264
    • Campbell, K.S.1
  • 24
    • 0033519453 scopus 로고    scopus 로고
    • Induction of NF-kappaB by the Akt/PKB kinase
    • Kane, L.P., V.S. Shapiro, D. Stokoe, and A. Weiss. 1999. Induction of NF-kappaB by the Akt/PKB kinase. Curr. Biol. 9:601-604.
    • (1999) Curr. Biol. , vol.9 , pp. 601-604
    • Kane, L.P.1    Shapiro, V.S.2    Stokoe, D.3    Weiss, A.4
  • 25
    • 0033517189 scopus 로고    scopus 로고
    • Nf-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes, O.N., L.D. Mayo, J.A. Gustin, S.R. Pfeffer, L.M. Pfeffer, and D.B. Donner. 1999. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature. 401:82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 26
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
    • Romashkova, J.A., and S.S. Makarov. 1999. NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature. 401:86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 27
    • 0029835940 scopus 로고    scopus 로고
    • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcgammaRIIB
    • Ono, M., S. Bolland, P. Tempst, and J.V. Ravetch. 1996. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcgammaRIIB. Nature. 383:263-266.
    • (1996) Nature , vol.383 , pp. 263-266
    • Ono, M.1    Bolland, S.2    Tempst, P.3    Ravetch, J.V.4
  • 28
    • 0030587116 scopus 로고    scopus 로고
    • Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP
    • Chacko, G.W., S. Tridandapani, J.E. Damen, L. Liu, G. Krystal, and K.M. Coggeshall. 1996. Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP. J. Immunol. 157:2234-2238.
    • (1996) J. Immunol. , vol.157 , pp. 2234-2238
    • Chacko, G.W.1    Tridandapani, S.2    Damen, J.E.3    Liu, L.4    Krystal, G.5    Coggeshall, K.M.6
  • 29
    • 8244232951 scopus 로고    scopus 로고
    • Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated Fc gammaRIIB during negative regulation of IgE-dependent mouse mast cell activation
    • Fong, D.C., O. Malbec, M. Arock, J.C. Cambier, W.H. Fridman, and M. Daeron. 1996. Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated Fc gammaRIIB during negative regulation of IgE-dependent mouse mast cell activation. Immunol. Lett. 54:83-91.
    • (1996) Immunol. Lett. , vol.54 , pp. 83-91
    • Fong, D.C.1    Malbec, O.2    Arock, M.3    Cambier, J.C.4    Fridman, W.H.5    Daeron, M.6
  • 30
    • 0029978202 scopus 로고    scopus 로고
    • The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
    • Damen, J.E., L. Liu, P. Rosten, R.K. Humphries, A.B. Jefferson, P.W. Majerus, and G. Krystal. 1996. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. Proc. Natl. Acad. Sci. USA. 93: 1689-1693.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1689-1693
    • Damen, J.E.1    Liu, L.2    Rosten, P.3    Humphries, R.K.4    Jefferson, A.B.5    Majerus, P.W.6    Krystal, G.7
  • 31
    • 0033548446 scopus 로고    scopus 로고
    • The sH2 domain-containing inositol 5′-phosphatase (SHIP) recruits the p85 subunit of phosphoinositide 3-kinase during FcgammaRIIb1-mediated inhibition of B cell receptor signaling
    • Gupta, N., A.M. Scharenberg, D.A. Fruman, L.C. Cantley, J.P. Kinet, and E.O. Long. 1999. The SH2 domain-containing inositol 5′-phosphatase (SHIP) recruits the p85 subunit of phosphoinositide 3-kinase during FcgammaRIIb1-mediated inhibition of B cell receptor signaling. J. Biol. Chem. 274: 7489-7494.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7489-7494
    • Gupta, N.1    Scharenberg, A.M.2    Fruman, D.A.3    Cantley, L.C.4    Kinet, J.P.5    Long, E.O.6
  • 33
    • 0343307005 scopus 로고    scopus 로고
    • Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling
    • Ono, M., H. Okada, S. Bolland, S. Yanagi, T. Kurosaki, and J.V. Ravetch. 1997. Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling. Cell. 90:293-301.
    • (1997) Cell. , vol.90 , pp. 293-301
    • Ono, M.1    Okada, H.2    Bolland, S.3    Yanagi, S.4    Kurosaki, T.5    Ravetch, J.V.6
  • 36
    • 0033597350 scopus 로고    scopus 로고
    • The src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with she and grb2 in antigen receptor-stimulated B lymphocytes
    • Harmer, S.L., and A.L. DeFranco. 1999. The src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with she and grb2 in antigen receptor-stimulated B lymphocytes. J. Biol. Chem. 274:12183-12191.
    • (1999) J. Biol. Chem. , vol.274 , pp. 12183-12191
    • Harmer, S.L.1    DeFranco, A.L.2
  • 38
    • 0028002840 scopus 로고
    • Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells
    • Gold, M.R., and R. Aebersold. 1994. Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells. J. Immunol. 152:42-50.
    • (1994) J. Immunol. , vol.152 , pp. 42-50
    • Gold, M.R.1    Aebersold, R.2
  • 39
    • 0027379716 scopus 로고
    • h1 splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells
    • h1 splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells. J. Immunol. 151:4431-4444.
    • (1993) J. Immunol. , vol.151 , pp. 4431-4444
    • Allman, D.M.1    Ferguson, S.E.2    Lentz, V.M.3    Cancro, M.P.4
  • 40
    • 0033568663 scopus 로고    scopus 로고
    • Distribution of the Src-homology-2-domain-containing inositol 5-phosphatase SHIP-2 in both non-haemopoietic and haemopoietic cells and possible involvement of SHIP-2 in negative signalling of B-cells
    • Muraille, E., X. Pesesse, C. Kuntz, and C. Erneux. 1999. Distribution of the Src-homology-2-domain-containing inositol 5-phosphatase SHIP-2 in both non-haemopoietic and haemopoietic cells and possible involvement of SHIP-2 in negative signalling of B-cells. Biochem. J. 342:697-705.
    • (1999) Biochem. J. , vol.342 , pp. 697-705
    • Muraille, E.1    Pesesse, X.2    Kuntz, C.3    Erneux, C.4
  • 42
    • 0033526816 scopus 로고    scopus 로고
    • B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
    • Loder, F., B. Mutschler, R.J. Ray, C.J. Paige, P. Sideras, R. Torres, M.C. Lamers, and R. Carsetti. 1999. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190:75-89.
    • (1999) J. Exp. Med. , vol.190 , pp. 75-89
    • Loder, F.1    Mutschler, B.2    Ray, R.J.3    Paige, C.J.4    Sideras, P.5    Torres, R.6    Lamers, M.C.7    Carsetti, R.8
  • 43
    • 0031738699 scopus 로고    scopus 로고
    • Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
    • Rolink, A.G., J. Andersson, and F. Melchers. 1998. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur. J. Immunol. 28:3738-3748.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3738-3748
    • Rolink, A.G.1    Andersson, J.2    Melchers, F.3
  • 44
    • 0033136628 scopus 로고    scopus 로고
    • Mutations affecting either generation or survival of cells influence the pool size of mature B cells
    • Rolink, A.G., T. Brocker, H. Bluethmann, M.H. Kosco-Vilbois, J. Andersson, and F. Melchers. 1999. Mutations affecting either generation or survival of cells influence the pool size of mature B cells. Immunity. 10:619-628.
    • (1999) Immunity , vol.10 , pp. 619-628
    • Rolink, A.G.1    Brocker, T.2    Bluethmann, H.3    Kosco-Vilbois, M.H.4    Andersson, J.5    Melchers, F.6
  • 45
    • 0344069651 scopus 로고    scopus 로고
    • Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells
    • Benschop, R.J., D. Melamed, D. Nemazee, and J.C. Cambier. 1999. Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. J. Exp. Med. 190:749-756.
    • (1999) J. Exp. Med. , vol.190 , pp. 749-756
    • Benschop, R.J.1    Melamed, D.2    Nemazee, D.3    Cambier, J.C.4
  • 46
    • 0029006329 scopus 로고
    • Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis
    • Norvell, A., L. Mandik, and J.G. Monroe. 1995. Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis. J. Immunol. 154:4404-4413.
    • (1995) J. Immunol. , vol.154 , pp. 4404-4413
    • Norvell, A.1    Mandik, L.2    Monroe, J.G.3
  • 47
    • 0030023652 scopus 로고    scopus 로고
    • Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45
    • Cyster, J.G., J.I. Healy, K. Kishihara, T.W. Mak, M.L. Thomas, and C.C. Goodnow. 1996. Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45. Nature. 381:325-328.
    • (1996) Nature , vol.381 , pp. 325-328
    • Cyster, J.G.1    Healy, J.I.2    Kishihara, K.3    Mak, T.W.4    Thomas, M.L.5    Goodnow, C.C.6
  • 49
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
    • Sato, S., A.S. Miller, M. Inaoki, C.B. Bock, P.J. Jansen, M.L. Tang, and T.F. Tedder. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity. 5:551-562.
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.6    Tedder, T.F.7
  • 50
    • 0032055828 scopus 로고    scopus 로고
    • Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
    • Cornall, R.J., J.G. Cyster, M.L. Hibbs, A.R. Dunn, K.L. Otipoby, E.A. Clark, and C.C. Goodnow. 1998. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity. 8:497-508.
    • (1998) Immunity , vol.8 , pp. 497-508
    • Cornall, R.J.1    Cyster, J.G.2    Hibbs, M.L.3    Dunn, A.R.4    Otipoby, K.L.5    Clark, E.A.6    Goodnow, C.C.7
  • 51
    • 0033179893 scopus 로고    scopus 로고
    • Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop
    • Fujimoto, M., A.P. Bradney, J.C. Poe, D.A. Steeber, and T.F. Tedder. 1999. Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop. Immunity. 11:191-200.
    • (1999) Immunity , vol.11 , pp. 191-200
    • Fujimoto, M.1    Bradney, A.P.2    Poe, J.C.3    Steeber, D.A.4    Tedder, T.F.5
  • 52
    • 0029094609 scopus 로고
    • Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
    • Engel, P., L.J. Zhou, D.C. Ord, S. Sato, B. Koller, and T.F. Tedder. 1995. Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. Immunity. 3:39-50.
    • (1995) Immunity , vol.3 , pp. 39-50
    • Engel, P.1    Zhou, L.J.2    Ord, D.C.3    Sato, S.4    Koller, B.5    Tedder, T.F.6
  • 53
    • 0030784484 scopus 로고    scopus 로고
    • CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes
    • Inaoki, M., S. Sato, B.C. Weintraub, C.C. Goodnow, and T.F. Tedder. 1997. CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J. Exp. Med. 186:1923-1931.
    • (1997) J. Exp. Med. , vol.186 , pp. 1923-1931
    • Inaoki, M.1    Sato, S.2    Weintraub, B.C.3    Goodnow, C.C.4    Tedder, T.F.5
  • 55
    • 0012946420 scopus 로고    scopus 로고
    • Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors
    • Iritani, B.M., J. Alberola-Ila, K.A. Forbush, and R.M. Perlmutter. 1999. Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors. Immunity. 10:713-722.
    • (1999) Immunity , vol.10 , pp. 713-722
    • Iritani, B.M.1    Alberola-Ila, J.2    Forbush, K.A.3    Perlmutter, R.M.4
  • 56
    • 0033389736 scopus 로고    scopus 로고
    • Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor and CD40 in human B cells
    • Sakata, N., H. Kawasome, N. Terada, P. Gerwins, G.L. Johnson, and E.W. Gelfand. 1999. Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor and CD40 in human B cells. Eur. J. Immunol. 29:2999-3008.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2999-3008
    • Sakata, N.1    Kawasome, H.2    Terada, N.3    Gerwins, P.4    Johnson, G.L.5    Gelfand, E.W.6
  • 58
  • 59
    • 0344936020 scopus 로고    scopus 로고
    • Inhibitory signaling by B cell Fc gamma RIIb
    • Coggeshall, K.M. 1998. Inhibitory signaling by B cell Fc gamma RIIb. Curr. Opin. Immunol. 10:306-312.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 306-312
    • Coggeshall, K.M.1
  • 61
    • 0030975468 scopus 로고    scopus 로고
    • The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of apoptosis
    • Liu, L., J.E. Damen, M.R. Hughes, I. Babic, F.R. Jirik, and G. Krystal. 1997. The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of apoptosis. J. Biol. Chem. 272:8983-8988.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8983-8988
    • Liu, L.1    Damen, J.E.2    Hughes, M.R.3    Babic, I.4    Jirik, F.R.5    Krystal, G.6
  • 62
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta, S.R., H. Dudek, X. Tao, S. Masters, H. Fu, Y. Gotoh, and M.E. Greenberg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 64
    • 0031433335 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
    • Brennan, P., J.W. Babbage, B.M. Burgering, B. Groner, K. Reif, and D.A. Cantrell. 1997. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity. 7:679-689.
    • (1997) Immunity , vol.7 , pp. 679-689
    • Brennan, P.1    Babbage, J.W.2    Burgering, B.M.3    Groner, B.4    Reif, K.5    Cantrell, D.A.6
  • 65
    • 0032530195 scopus 로고    scopus 로고
    • The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation
    • Huber, M., C.D. Helgason, J.E. Damen, L. Liu, R.K. Humphries, and G. Krystal. 1998. The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation. Proc. Natl. Acad. Sci. USA. 95:11330-11335.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11330-11335
    • Huber, M.1    Helgason, C.D.2    Damen, J.E.3    Liu, L.4    Humphries, R.K.5    Krystal, G.6


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