-
1
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E. V., Rivino, L., Geginat, J., Jarrossay, D., Gattorno, M., Lanzavecchia, A., Sallusto, F., & Napolitani, G. (2007). Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol., 8, 639-646.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
2
-
-
53049107609
-
New insights into mechanisms of immunoregulation in 2007
-
Akdis, C. A. (2008). New insights into mechanisms of immunoregulation in 2007. J. Allergy Clin. Immunol., 122, 700-709.
-
(2008)
J. Allergy Clin. Immunol.
, vol.122
, pp. 700-709
-
-
Akdis, C.A.1
-
3
-
-
71549131604
-
Discrete dynamic modeling of cellular signaling networks
-
Albert, R., & Wang, R. S. (2009). Discrete dynamic modeling of cellular signaling networks. Methods Enzymol., 467, 281-306.
-
(2009)
Methods Enzymol.
, vol.467
, pp. 281-306
-
-
Albert, R.1
Wang, R.S.2
-
4
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells
-
Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006). Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature, 441, 235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
5
-
-
46249112705
-
Boolean network models of cellular regulation: prospects and limitations
-
Bornholdt, S. (2008). Boolean network models of cellular regulation: prospects and limitations. J. R. Soc. Interface, 5, S85-S94.
-
(2008)
J. R. Soc. Interface
, vol.5
-
-
Bornholdt, S.1
-
6
-
-
77649242104
-
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
-
Busse, D., de la Rosa, M., Hobiger, K., Thurley, K., Flossdorf, M., Scheffold, A., & Höfer, T. (2010). Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proc. Natl. Acad. Sci. USA, 107, 3058-3063.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3058-3063
-
-
Busse, D.1
de la Rosa, M.2
Hobiger, K.3
Thurley, K.4
Flossdorf, M.5
Scheffold, A.6
Höfer, T.7
-
7
-
-
0034002472
-
The costimulatory effect of IL-18 on the induction of antigenspecific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit
-
Chang, J. T., Segal, B. M., Nakanishi, K., Okamura, H., & Shevach, E. M. (2000). The costimulatory effect of IL-18 on the induction of antigenspecific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit. Eur. J. Immunol., 30, 1113-1119.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1113-1119
-
-
Chang, J.T.1
Segal, B.M.2
Nakanishi, K.3
Okamura, H.4
Shevach, E.M.5
-
8
-
-
0033662322
-
SOCS proteins, regulators of intracellular signaling
-
Chen, X. P., Losman, J. A., & Rothman, P. (2000). SOCS proteins, regulators of intracellular signaling. Immunity, 13, 287-290.
-
(2000)
Immunity
, vol.13
, pp. 287-290
-
-
Chen, X.P.1
Losman, J.A.2
Rothman, P.3
-
9
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
Chen, W., Jin, W., Hardegen, N., Lei, K., Li, L., Marinos, N., McGrady, G., & Wahl, S. M. (2003). Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med., 198, 1875-1886.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
10
-
-
0036207347
-
Modeling and simulation of genetic regulatory systems: a literature review
-
De Jong, H. (2002). Modeling and simulation of genetic regulatory systems: a literature review. J. Comput. Biol., 9, 67-103.
-
(2002)
J. Comput. Biol.
, vol.9
, pp. 67-103
-
-
De Jong, H.1
-
11
-
-
38949210153
-
Dynamic simulation of regulatory networks using SQUAD
-
Di Cara, A., Garg, A., De Micheli, G., Xenarios, I., & Mendoza, L. (2007). Dynamic simulation of regulatory networks using SQUAD. BMC Bioinform., 8, 462.
-
(2007)
BMC Bioinform.
, vol.8
, pp. 462
-
-
Di Cara, A.1
Garg, A.2
De Micheli, G.3
Xenarios, I.4
Mendoza, L.5
-
12
-
-
0034502224
-
Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1
-
Diehl, S., Anguita, J., Hoffmeyer, A., Zapton, T., Ihle, J. N., Fikrig, E., & Rincón, M. (2000). Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity, 13, 805-815.
-
(2000)
Immunity
, vol.13
, pp. 805-815
-
-
Diehl, S.1
Anguita, J.2
Hoffmeyer, A.3
Zapton, T.4
Ihle, J.N.5
Fikrig, E.6
Rincón, M.7
-
13
-
-
18744386097
-
IFN-γ represses IL-4 expression via IRF-1 and IRF-2
-
Elser, B., Lohoff, M., Kock, S., Giaisi, M., Kirchhoff, S., Krammer, P. H., & Li-Weber, M. (2002). IFN-γ represses IL-4 expression via IRF-1 and IRF-2. Immunity, 17, 703-712.
-
(2002)
Immunity
, vol.17
, pp. 703-712
-
-
Elser, B.1
Lohoff, M.2
Kock, S.3
Giaisi, M.4
Kirchhoff, S.5
Krammer, P.H.6
Li-Weber, M.7
-
14
-
-
2142645808
-
Cutting edge: TGF-β induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
-
Fantini, M. C., Becker, C., Monteleone, G., Pallone, F., Galle, P. R., & Neurath, M. F. (2004). Cutting edge: TGF-β induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J. Immunol., 172, 5149-5153.
-
(2004)
J. Immunol.
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
15
-
-
38049136890
-
The Basic Immune Simulator: an agent-based model to study the interactions between innate and adaptive immunity
-
Folcik, V. A., An, G. C., & Orosz, C. G. (2007). The Basic Immune Simulator: an agent-based model to study the interactions between innate and adaptive immunity. Theor. Biol. Med. Model., 4, 39.
-
(2007)
Theor. Biol. Med. Model.
, vol.4
, pp. 39
-
-
Folcik, V.A.1
An, G.C.2
Orosz, C.G.3
-
16
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
Gavin, M. A., Rasmussen, J. P., Fontenot, J. D., Vasta, V., Manganiello, V. C., Beavo, J. A., & Rudensky, A. Y. (2007). Foxp3-dependent programme of regulatory T-cell differentiation. Nature, 445, 771-775.
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
Vasta, V.4
Manganiello, V.C.5
Beavo, J.A.6
Rudensky, A.Y.7
-
17
-
-
67649314093
-
Dynamical approaches to modeling developmental gene regulatory networks
-
Geard, N., & Willadsen, K. (2009). Dynamical approaches to modeling developmental gene regulatory networks. Birth Defects Res. C, Embryo Today, 87, 131-142.
-
(2009)
Birth Defects Res. C, Embryo Today
, vol.87
, pp. 131-142
-
-
Geard, N.1
Willadsen, K.2
-
18
-
-
0033795196
-
Interferons: cell signalling, immune modulation, antiviral responses and virus countermeasures
-
Goodbourn, S., Didcock, L., & Randal, R. E. (2000). Interferons: cell signalling, immune modulation, antiviral responses and virus countermeasures. J. Gen. Virol., 81, 2341-2364.
-
(2000)
J. Gen. Virol.
, vol.81
, pp. 2341-2364
-
-
Goodbourn, S.1
Didcock, L.2
Randal, R.E.3
-
19
-
-
0035224492
-
Distinct gene expression profiles of human type 1 and type 2 T helper cells
-
RESEARCH0022
-
Hamalainen, H., Zhou, H., Chou, W., Hashizume, H., Heller, R., & Lahesmaa, R. (2001). Distinct gene expression profiles of human type 1 and type 2 T helper cells. Genome Biol., 2, RESEARCH0022.
-
(2001)
Genome Biol.
, vol.2
-
-
Hamalainen, H.1
Zhou, H.2
Chou, W.3
Hashizume, H.4
Heller, R.5
Lahesmaa, R.6
-
20
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich, P. C., Behrmann, I., Müller-Newen, G., Schaper, F., & Graeve, L. (1998). Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J., 334, 297-314.
-
(1998)
Biochem. J.
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Müller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
21
-
-
0028874351
-
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha betatransgenic model
-
Hosken, N. A., Shibuya, K., Heath, A. W., Murphy, K. M., & O'Garra, A. (1995). The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha betatransgenic model. J. Exp. Med., 182, 1579-1584.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1579-1584
-
-
Hosken, N.A.1
Shibuya, K.2
Heath, A.W.3
Murphy, K.M.4
O'Garra, A.5
-
22
-
-
66449090934
-
Reprogramming cell fates: reconciling rarity with robustness
-
Huang, S. (2009). Reprogramming cell fates: reconciling rarity with robustness. BioEssays, 31, 546-560.
-
(2009)
BioEssays
, vol.31
, pp. 546-560
-
-
Huang, S.1
-
23
-
-
3142682595
-
T cell receptor signaling: beyond complex complexes
-
Huang, Y., & Wange, R. L. (2004). T cell receptor signaling: beyond complex complexes. J. Biol. Chem., 279, 28827-28830.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28827-28830
-
-
Huang, Y.1
Wange, R.L.2
-
24
-
-
33748588423
-
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, I. I., McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J., & Littman, D. R. (2006). The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell, 126, 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
25
-
-
0033526110
-
Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 response in IL-1 receptor-associated kinase (IRAK)-deficient mice
-
Kanakaraj, P., Ngo, K., Wu, Y., Angulo, A., Ghazal, P., Harris, C. A., Siekierka, J. J., Peterson, P. A., & Fung-Leung, W. P. (1999). Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 response in IL-1 receptor-associated kinase (IRAK)-deficient mice. J. Exp. Med., 189, 1129-1138.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1129-1138
-
-
Kanakaraj, P.1
Ngo, K.2
Wu, Y.3
Angulo, A.4
Ghazal, P.5
Harris, C.A.6
Siekierka, J.J.7
Peterson, P.A.8
Fung-Leung, W.P.9
-
26
-
-
0023662006
-
Model analysis of the bases of multistationarity in the humoral immune response
-
Kaufman, M., & Thomas, R. (1987). Model analysis of the bases of multistationarity in the humoral immune response. J. Theor. Biol., 129, 141-162.
-
(1987)
J. Theor. Biol.
, vol.129
, pp. 141-162
-
-
Kaufman, M.1
Thomas, R.2
-
27
-
-
0022376616
-
Towards a logical analysis of the immune response
-
Kaufman, M., Urbain, J., & Thomas, R. (1985). Towards a logical analysis of the immune response. J. Theor. Biol., 114, 527-561.
-
(1985)
J. Theor. Biol.
, vol.114
, pp. 527-561
-
-
Kaufman, M.1
Urbain, J.2
Thomas, R.3
-
28
-
-
0038539290
-
Of JAKs, STATs, blind watchmakers, jeeps and trains
-
Kerr, I. M., Costa-Pereira, A. P., Lillemeier, B. F., & Strobl, B. (2003). Of JAKs, STATs, blind watchmakers, jeeps and trains. FEBS Lett., 546, 1-5.
-
(2003)
FEBS Lett.
, vol.546
, pp. 1-5
-
-
Kerr, I.M.1
Costa-Pereira, A.P.2
Lillemeier, B.F.3
Strobl, B.4
-
29
-
-
58149159905
-
Network modeling of signal transduction: establishing the global view
-
Kestler, H. A., Wawra, C., Kracher, B., & Kühl, M. (2008). Network modeling of signal transduction: establishing the global view. BioEssays, 30, 1110-1125.
-
(2008)
BioEssays
, vol.30
, pp. 1110-1125
-
-
Kestler, H.A.1
Wawra, C.2
Kracher, B.3
Kühl, M.4
-
30
-
-
0034658583
-
Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
-
Kotenko, S. V., & Pestka, S. (2000). Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene, 19, 2557-2565.
-
(2000)
Oncogene
, vol.19
, pp. 2557-2565
-
-
Kotenko, S.V.1
Pestka, S.2
-
31
-
-
0034801684
-
SOCS proteins: negative regulators of cytokine signaling
-
Krebs, D. L., & Hilton, D. J. (2001). SOCS proteins: negative regulators of cytokine signaling. Stem Cells, 19, 378-387.
-
(2001)
Stem Cells
, vol.19
, pp. 378-387
-
-
Krebs, D.L.1
Hilton, D.J.2
-
32
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence, A., Tato, C. M., Davidson, T. S., Kanno, Y., Chen, Z., Yao, Z., Blank, R. B., Meylan, F., Siegel, R., Hennighausen, L., Shevach, E. M., & O'Shea, J. J. (2007). Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity, 26, 371-381.
-
(2007)
Immunity
, vol.26
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
Kanno, Y.4
Chen, Z.5
Yao, Z.6
Blank, R.B.7
Meylan, F.8
Siegel, R.9
Hennighausen, L.10
Shevach, E.M.11
O'Shea, J.J.12
-
33
-
-
0035910037
-
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
-
Lighvani, A. A., Frucht, D. M., Jankovic, D., Yamane, H., Aliberti, J., Hissong, B. D., Nguyen, B. V., Gadina, M., Sher, A., Paul, W. E., & O'Shea, J. J. (2001). T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells. Proc. Natl. Acad. Sci. USA, 98, 15137-15142.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15137-15142
-
-
Lighvani, A.A.1
Frucht, D.M.2
Jankovic, D.3
Yamane, H.4
Aliberti, J.5
Hissong, B.D.6
Nguyen, B.V.7
Gadina, M.8
Sher, A.9
Paul, W.E.10
O'Shea, J.J.11
-
34
-
-
45149109643
-
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+Foxp3+RORgammat+T cells
-
Lochner, M., Peduto, L., Cherrier, M., Sawa, S., Langa, F., Varona, R., Riethmacher, D., Si-Tahar, M., Di Santo, J. P., & Eberl, G. (2008). In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+Foxp3+RORgammat+T cells. J. Exp. Med., 205, 1381-1393.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1381-1393
-
-
Lochner, M.1
Peduto, L.2
Cherrier, M.3
Sawa, S.4
Langa, F.5
Varona, R.6
Riethmacher, D.7
Si-Tahar, M.8
Di Santo, J.P.9
Eberl, G.10
-
35
-
-
0033120880
-
Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
-
Losman, J. A., Chen, X. P., Hilton, D., & Rothman, P. (1999). Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J. Immunol., 162, 3770-3774.
-
(1999)
J. Immunol.
, vol.162
, pp. 3770-3774
-
-
Losman, J.A.1
Chen, X.P.2
Hilton, D.3
Rothman, P.4
-
36
-
-
63549100975
-
Canalization of gene expression and domain shifts in the Drosophila blastoderm by dynamical attractors
-
Manu, Surkova, S., Spirov, A. V., Gursky, V. V., Janssens, H., Kim, A. R., Radulescu, O., Vanario-Alonso, C. E., Sharp, D. H., Samsonova, M., & Reinitz, J. (2009). Canalization of gene expression and domain shifts in the Drosophila blastoderm by dynamical attractors. PLoS Comput. Biol., 5, e1000303.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Manu1
Surkova, S.2
Spirov, A.V.3
Gursky, V.V.4
Janssens, H.5
Kim, A.R.6
Radulescu, O.7
Vanario-Alonso, C.E.8
Sharp, D.H.9
Samsonova, M.10
Reinitz, J.11
-
37
-
-
33646345600
-
A network model for the control of the differentiation process in Th cells
-
Mendoza, L. (2006). A network model for the control of the differentiation process in Th cells. Biosystems, 84, 101-114.
-
(2006)
Biosystems
, vol.84
, pp. 101-114
-
-
Mendoza, L.1
-
38
-
-
0032555224
-
Dynamics of the genetic regulatory network for flowering in Arabidopsis thaliana
-
Mendoza, L., & Alvarez-Buylla, E. R. (1998). Dynamics of the genetic regulatory network for flowering in Arabidopsis thaliana. J. Theor. Biol., 193, 307-319.
-
(1998)
J. Theor. Biol.
, vol.193
, pp. 307-319
-
-
Mendoza, L.1
Alvarez-Buylla, E.R.2
-
39
-
-
78149362061
-
A robust model to describe the differentiation of T-helper cells
-
Mendoza, L., & Pardo, F. (2010). A robust model to describe the differentiation of T-helper cells. Theory Biosci., 129, 283-293.
-
(2010)
Theory Biosci.
, vol.129
, pp. 283-293
-
-
Mendoza, L.1
Pardo, F.2
-
40
-
-
33646346114
-
A method for the generation of standardized qualitative dynamical systems of regulatory networks
-
Mendoza, L., & Xenarios, I. (2006). A method for the generation of standardized qualitative dynamical systems of regulatory networks. Theor. Biol. Med. Model., 3, 13.
-
(2006)
Theor. Biol. Med. Model.
, vol.3
, pp. 13
-
-
Mendoza, L.1
Xenarios, I.2
-
41
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov, R. (2007). Recognition of microorganisms and activation of the immune response. Nature, 449, 819-826.
-
(2007)
Nature
, vol.449
, pp. 819-826
-
-
Medzhitov, R.1
-
42
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
Moore, K. W., de Waal Malefyt, R., Coffman, R., & O'Garra, A. (2001). Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol., 19, 683-765.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
de Waal Malefyt, R.2
Coffman, R.3
O'Garra, A.4
-
43
-
-
0035827347
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
-
Mullen, A. C., High, F. A., Hutchins, A. S., Lee, H. W., Villarino, A. V., Livingston, D. M., Kung, A. L., Cereb, N., Yao, T. P., Yang, S. Y., & Reiner, S. L. (2001). Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science, 292, 1907-1910.
-
(2001)
Science
, vol.292
, pp. 1907-1910
-
-
Mullen, A.C.1
High, F.A.2
Hutchins, A.S.3
Lee, H.W.4
Villarino, A.V.5
Livingston, D.M.6
Kung, A.L.7
Cereb, N.8
Yao, T.P.9
Yang, S.Y.10
Reiner, S.L.11
-
44
-
-
0036885067
-
The lineage decisions on helper T cells
-
Murphy, K. M., & Reiner, S. L. (2002). The lineage decisions on helper T cells. Nat. Rev. Immunol., 2, 933-944.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
45
-
-
78049424847
-
Diversity and plasticity of Th cell types predicted from regulatory network modelling
-
Naldi, A., Carneiro, J., Chaouiya, C., & Thieffry, D. (2010). Diversity and plasticity of Th cell types predicted from regulatory network modelling. PLoS Comput. Biol., 6, e1000912.
-
(2010)
PLoS Comput. Biol.
, vol.6
-
-
Naldi, A.1
Carneiro, J.2
Chaouiya, C.3
Thieffry, D.4
-
46
-
-
0031179124
-
Expression and role in apoptosis of the alpha- and β-chains of the IFN-γ receptor in human Th1 and Th2 clones
-
Novelli, F., D'Elios, M. M., Bernabei, P., Ozmen, L., Rigamonti, L., Almerigogna, F., Forni, G., & Del Prete, G. (1997). Expression and role in apoptosis of the alpha- and β-chains of the IFN-γ receptor in human Th1 and Th2 clones. J. Immunol., 159, 206-213.
-
(1997)
J. Immunol.
, vol.159
, pp. 206-213
-
-
Novelli, F.1
D'Elios, M.M.2
Bernabei, P.3
Ozmen, L.4
Rigamonti, L.5
Almerigogna, F.6
Forni, G.7
Del Prete, G.8
-
47
-
-
77649220954
-
Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
-
O'Shea, J. J., & Paul, W. E. (2010). Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science, 327, 1098-1102.
-
(2010)
Science
, vol.327
, pp. 1098-1102
-
-
O'Shea, J.J.1
Paul, W.E.2
-
48
-
-
59749087126
-
DC activated via dectin-1 convert Treg into IL-17 producers
-
Osorio, F., LeibundGut-Landmann, S., Lochner, M., Lahl, K., Sparwasser, T., Eberl, G., & Reis e Sousa, C. (2008). DC activated via dectin-1 convert Treg into IL-17 producers. Eur. J. Immunol., 38, 3274-3281.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 3274-3281
-
-
Osorio, F.1
LeibundGut-Landmann, S.2
Lochner, M.3
Lahl, K.4
Sparwasser, T.5
Eberl, G.6
Reis, E.7
Sousa, C.8
-
49
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
Ouyang, W., Löhning, M., Gao, Z., Assenmacher, M., Ranganath, S., Radbruch, A., & Murphy, K. M. (2000). Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity, 12, 27-37.
-
(2000)
Immunity
, vol.12
, pp. 27-37
-
-
Ouyang, W.1
Löhning, M.2
Gao, Z.3
Assenmacher, M.4
Ranganath, S.5
Radbruch, A.6
Murphy, K.M.7
-
50
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
-
Parham, C., Chirica, M., Timans, J., Vaisberg, E., Travis, M., Cheung, J., Pflanz, S., Zhang, R., Singh, K., Vega, F., To, W., Wagner, J., O'Farrell, A. M., McClanahan, T., Zurawski, S., Hannum, C., Gorman, D., Rennick, D. M., Kastelein, D. A., de Waal Malefyt, R., & Moore, K. W. (2002). A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R. J. Immunol., 168, 5699-5708.
-
(2002)
J. Immunol.
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.9
Vega, F.10
To, W.11
Wagner, J.12
O'Farrell, A.M.13
McClanahan, T.14
Zurawski, S.15
Hannum, C.16
Gorman, D.17
Rennick, D.M.18
Kastelein, D.A.19
de Waal Malefyt, R.20
Moore, K.W.21
more..
-
51
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y. H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., & Dong, C. (2005). A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol., 6, 1133-1141.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
52
-
-
0037093955
-
Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells
-
Porter, C. M., & Clipstone, N. A. (2002). Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells. J. Immunol., 168, 4936-4945.
-
(2002)
J. Immunol.
, vol.168
, pp. 4936-4945
-
-
Porter, C.M.1
Clipstone, N.A.2
-
53
-
-
51549097819
-
Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo
-
Radhakrishnan, S., Cabrera, R., Schenk, E. L., Nava-Parada, P., Bell, M. P., van Keulen, V. P., Marler, R. J., Felts, S. J., & Pease, L. R. (2008). Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo. J. Immunol., 181, 3137-3147.
-
(2008)
J. Immunol.
, vol.181
, pp. 3137-3147
-
-
Radhakrishnan, S.1
Cabrera, R.2
Schenk, E.L.3
Nava-Parada, P.4
Bell, M.P.5
van Keulen, V.P.6
Marler, R.J.7
Felts, S.J.8
Pease, L.R.9
-
54
-
-
0035076179
-
Structure and specificity of GATA proteins in Th2 development
-
Ranganath, S., & Murphy, K. M. (2001). Structure and specificity of GATA proteins in Th2 development. Mol. Cell. Biol., 21, 2716-2725.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2716-2725
-
-
Ranganath, S.1
Murphy, K.M.2
-
55
-
-
0033985193
-
Surface expression of the IFN-γR2 chain is regulated by intracellular trafficking in human T lymphocytes
-
Rigamonti, L., Ariotti, S., Losana, G., Gradini, R., Russo, M. A., Jouanguy, E., Casanova, J. L., Forni, G., & Novelli, F. (2000). Surface expression of the IFN-γR2 chain is regulated by intracellular trafficking in human T lymphocytes. J. Immunol., 164, 201-207.
-
(2000)
J. Immunol.
, vol.164
, pp. 201-207
-
-
Rigamonti, L.1
Ariotti, S.2
Losana, G.3
Gradini, R.4
Russo, M.A.5
Jouanguy, E.6
Casanova, J.L.7
Forni, G.8
Novelli, F.9
-
56
-
-
0031034051
-
Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells
-
Rincon, M., & Flavell, R. A. (1997). Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. Mol. Cell. Biol., 17, 1522-1534.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1522-1534
-
-
Rincon, M.1
Flavell, R.A.2
-
57
-
-
84859054645
-
A Boolean network model of the FA/BRCA pathway
-
Rodríguez, A., Sosa, D., Torres, L., Molina, B., Frías, S., & Mendoza, L. (2012). A Boolean network model of the FA/BRCA pathway. Bioinformatics, 28, 858-866.
-
(2012)
Bioinformatics
, vol.28
, pp. 858-866
-
-
Rodríguez, A.1
Sosa, D.2
Torres, L.3
Molina, B.4
Frías, S.5
Mendoza, L.6
-
58
-
-
0034120709
-
IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-γ
-
Saito, H., Morita, Y., Fujimoto, M., Narazaki, M., Naka, T., & Kishimoto, T. (2000). IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-γ. J. Immunol., 164, 5833-5843.
-
(2000)
J. Immunol.
, vol.164
, pp. 5833-5843
-
-
Saito, H.1
Morita, Y.2
Fujimoto, M.3
Narazaki, M.4
Naka, T.5
Kishimoto, T.6
-
59
-
-
0041381349
-
Segmenting the fly embryo: a logical analysis of the pair-rule cross-regulatory module
-
Sánchez, L., & Thieffry, D. (2003). Segmenting the fly embryo: a logical analysis of the pair-rule cross-regulatory module. J. Theor. Biol., 224, 517-537.
-
(2003)
J. Theor. Biol.
, vol.224
, pp. 517-537
-
-
Sánchez, L.1
Thieffry, D.2
-
60
-
-
61449309306
-
Segmenting the fly embryo: logical analysis of the role of the segment polarity cross-regulatory module
-
Sánchez, L., Chaouiya, C., & Thieffry, D. (2008). Segmenting the fly embryo: logical analysis of the role of the segment polarity cross-regulatory module. Int. J. Dev. Biol., 52, 1059-1075.
-
(2008)
Int. J. Dev. Biol.
, vol.52
, pp. 1059-1075
-
-
Sánchez, L.1
Chaouiya, C.2
Thieffry, D.3
-
61
-
-
77952640771
-
The Arabidopsis thaliana flower organ specification gene regulatory network determines a robust differentiation process
-
Sánchez-Corrales, Y. E., Alvarez-Buylla, E. R., & Mendoza, L. (2010). The Arabidopsis thaliana flower organ specification gene regulatory network determines a robust differentiation process. J. Theor. Biol., 264, 971-983.
-
(2010)
J. Theor. Biol.
, vol.264
, pp. 971-983
-
-
Sánchez-Corrales, Y.E.1
Alvarez-Buylla, E.R.2
Mendoza, L.3
-
62
-
-
44349185622
-
Implementation of a regulatory gene network to stimulate the TH1/2 differentiation in an agent-based model of hypersensitivity reactions
-
Santoni, D., Pedicini, M., & Castiglione, F. (2008). Implementation of a regulatory gene network to stimulate the TH1/2 differentiation in an agent-based model of hypersensitivity reactions. Bioinformatics, 24, 1374-1380.
-
(2008)
Bioinformatics
, vol.24
, pp. 1374-1380
-
-
Santoni, D.1
Pedicini, M.2
Castiglione, F.3
-
63
-
-
0032960198
-
IL-4 enhances IL-10 gene expression in murine Th2 cells in the absence of TCR engagement
-
Schmidt-Weber, C. B., Alexander, S. I., Henault, L. E., James, L., & Lichtman, A. H. (1999). IL-4 enhances IL-10 gene expression in murine Th2 cells in the absence of TCR engagement. J. Immunol., 162, 238-244.
-
(1999)
J. Immunol.
, vol.162
, pp. 238-244
-
-
Schmidt-Weber, C.B.1
Alexander, S.I.2
Henault, L.E.3
James, L.4
Lichtman, A.H.5
-
64
-
-
33746365086
-
The lifestyle of naturally occurring CD4+CD25+Foxp3+ regulatory T cells
-
Shevach, E. M., DiPaolo, R. A., Andersson, J., Zhao, D. M., Stephens, G. L., & Thornton, A. M. (2006). The lifestyle of naturally occurring CD4+CD25+Foxp3+ regulatory T cells. Immunol. Rev., 212, 60-73.
-
(2006)
Immunol. Rev.
, vol.212
, pp. 60-73
-
-
Shevach, E.M.1
DiPaolo, R.A.2
Andersson, J.3
Zhao, D.M.4
Stephens, G.L.5
Thornton, A.M.6
-
65
-
-
0038682002
-
Mechanisms of TGF-β signaling from cell membrane to the nucleus
-
Shi, Y., & Massagué, J. (2003). Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell, 113, 685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massagué, J.2
-
66
-
-
0035898446
-
Regulation of interleukin (IL)-18 receptor alpha chain expression on CD4+ T cells during T helper (Th)1/Th2 differentiation: critical downregulatory role of IL-4
-
Smeltz, R. B., Chen, J., Hu-Li, J., & Shevach, E. M. (2001). Regulation of interleukin (IL)-18 receptor alpha chain expression on CD4+ T cells during T helper (Th)1/Th2 differentiation: critical downregulatory role of IL-4. J. Exp. Med., 194, 143-153.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 143-153
-
-
Smeltz, R.B.1
Chen, J.2
Hu-Li, J.3
Shevach, E.M.4
-
67
-
-
3142735120
-
In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3
-
Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, A., Kaestel, C. G., Nissen, M. H., Ropke, C., Skov, S., & Ødum, N. (2004). In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3. Leukemia, 18, 1288-1295.
-
(2004)
Leukemia
, vol.18
, pp. 1288-1295
-
-
Sommer, V.H.1
Clemmensen, O.J.2
Nielsen, O.3
Wasik, M.4
Lovato, P.5
Brender, C.6
Eriksen, K.W.7
Woetmann, A.8
Kaestel, C.G.9
Nissen, M.H.10
Ropke, C.11
Skov, S.12
Ødum, N.13
-
68
-
-
33846966636
-
A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
-
Steinman, L. (2007). A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat. Med., 13, 139-145.
-
(2007)
Nat. Med.
, vol.13
, pp. 139-145
-
-
Steinman, L.1
-
69
-
-
8044250881
-
Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
Szabo, S. J., Dighe, A. S., Gubler, U., & Murphy, K. M. (1997). Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med., 185, 817-824.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 817-824
-
-
Szabo, S.J.1
Dighe, A.S.2
Gubler, U.3
Murphy, K.M.4
-
70
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G., & Glimcher, L. H. (2000). A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell, 100, 655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
71
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder, W. E., van Deursen, J. M., Yamamoto, K., Tripp, R. A., Sarawar, S. R., Carson, R. T., Sangster, M. Y., Vignali, D. A., Doherty, P. C., Grosveld, G. C., & Ihle, J. N. (1996). Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature, 382, 171-174.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.8
Doherty, P.C.9
Grosveld, G.C.10
Ihle, J.N.11
-
72
-
-
0007712725
-
Multistationarity, the basis of cell differentiation and memory. I. Structural conditions of multistationarity and other nontrivial behavior
-
Thomas, R., & Kaufman, M. (2001a). Multistationarity, the basis of cell differentiation and memory. I. Structural conditions of multistationarity and other nontrivial behavior. Chaos, 11, 170-179.
-
(2001)
Chaos
, vol.11
, pp. 170-179
-
-
Thomas, R.1
Kaufman, M.2
-
73
-
-
0035582202
-
Multistationarity, the basis of cell differentiation and memory. II. Logical analysis of regulatory networks in terms of feedback circuits
-
Thomas, R., & Kaufman, M. (2001b). Multistationarity, the basis of cell differentiation and memory. II. Logical analysis of regulatory networks in terms of feedback circuits. Chaos, 11, 180-195.
-
(2001)
Chaos
, vol.11
, pp. 180-195
-
-
Thomas, R.1
Kaufman, M.2
-
74
-
-
0037342749
-
GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rβ2 chain or T-bet
-
Usui, T., Nishikomori, R., Kitani, A., & Strober, W. (2003). GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rβ2 chain or T-bet. Immunity, 18, 415-428.
-
(2003)
Immunity
, vol.18
, pp. 415-428
-
-
Usui, T.1
Nishikomori, R.2
Kitani, A.3
Strober, W.4
-
75
-
-
32244442562
-
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006). TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity, 24, 179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
76
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan, Y. Y., & Flavell, R. A. (2007). Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature, 445, 766-770.
-
(2007)
Nature
, vol.445
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
77
-
-
77449090327
-
How diverse-CD4 effector T cells and their functions
-
Wan, Y. Y., & Flavell, R. A. (2009). How diverse-CD4 effector T cells and their functions. Mol. Cell. Biol., 1, 20-36.
-
(2009)
Mol. Cell. Biol.
, vol.1
, pp. 20-36
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
78
-
-
33744984785
-
Th17: An effector CD4 T cell lineage with regulatory T cell ties
-
Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M., & Murphy, K. M. (2006). Th17: An effector CD4 T cell lineage with regulatory T cell ties. Immunity, 24, 677-688.
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
79
-
-
84879181252
-
Building qualitative models of plant regulatory networks with SQUAD
-
Weinstein, N., & Mendoza, L. (2012). Building qualitative models of plant regulatory networks with SQUAD. Front. Plant Sci., 3, 72.
-
(2012)
Front. Plant Sci.
, vol.3
, pp. 72
-
-
Weinstein, N.1
Mendoza, L.2
-
80
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams, L. M., & Rudensky, A. Y. (2007). Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol., 8, 277-284.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
81
-
-
70449481350
-
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
-
Wittmann, D. M., Krumsiek, J., Saez-Rodriguez, J., Lauffenburger, D. A., Klamt, S., & Theis, F. J. (2009). Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling. BMC Syst. Biol., 3, 98.
-
(2009)
BMC Syst. Biol.
, vol.3
, pp. 98
-
-
Wittmann, D.M.1
Krumsiek, J.2
Saez-Rodriguez, J.3
Lauffenburger, D.A.4
Klamt, S.5
Theis, F.J.6
-
82
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
Yang, X. O., Panopoulos, A. D., Nurieva, R., Chang, S. H., Wang, D., Watowich, S. S., & Dong, C. (2007). STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J. Biol. Chem., 282, 9358-9363.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9358-9363
-
-
Yang, X.O.1
Panopoulos, A.D.2
Nurieva, R.3
Chang, S.H.4
Wang, D.5
Watowich, S.S.6
Dong, C.7
-
83
-
-
34548742977
-
Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells
-
Zhong, X., Gao, W., Degauque, N., Bai, C., Lu, Y., Kenny, J., Oukka, M., Strom, T. B., & Rothstein, T. L. (2007). Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells. Eur. J. Immunol., 37, 2400-2404.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 2400-2404
-
-
Zhong, X.1
Gao, W.2
Degauque, N.3
Bai, C.4
Lu, Y.5
Kenny, J.6
Oukka, M.7
Strom, T.B.8
Rothstein, T.L.9
-
84
-
-
43449135305
-
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
-
Zhou, L., Lopes, J. E., Chong, M. M. W., Ivanov, I. I., Min, R., Victora, G. D., Shen, Y., Du, J., Rubtsov, Y. P., Rudensky, A. Y., Ziegler, S. F., & Littman, D. R. (2008). TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function. Nature, 453, 236-240.
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.W.3
Ivanov, I.I.4
Min, R.5
Victora, G.D.6
Shen, Y.7
Du, J.8
Rubtsov, Y.P.9
Rudensky, A.Y.10
Ziegler, S.F.11
Littman, D.R.12
-
85
-
-
65549115862
-
Plasticity of CD4+ T cell lineage differentiation
-
Zhou, L., Chong, M. M. W., & Littman, D. R. (2009). Plasticity of CD4+ T cell lineage differentiation. Immunity, 30, 646-655.
-
(2009)
Immunity
, vol.30
, pp. 646-655
-
-
Zhou, L.1
Chong, M.M.W.2
Littman, D.R.3
|