메뉴 건너뛰기




Volumn 28, Issue 6, 2012, Pages 858-866

A Boolean network model of the FA/BRCA pathway

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; FANCONI ANEMIA PROTEIN;

EID: 84859054645     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/bts036     Document Type: Article
Times cited : (38)

References (53)
  • 1
    • 67650451108 scopus 로고    scopus 로고
    • Fanconi anemia and its diagnosis
    • Auerbach, A. D. (2009) Fanconi anemia and its diagnosis. Mutat. Res., 668, 4-10.
    • (2009) Mutat. Res. , vol.668 , pp. 4-10
    • Auerbach, A.D.1
  • 2
    • 33847737716 scopus 로고    scopus 로고
    • DNA damage checkpoints: from initiation to recovery or adaptation
    • Bartek, J. and Lukas, J. (2007) DNA damage checkpoints: from initiation to recovery or adaptation. Curr. Opin. Cell Biol., 19, 238-245.
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 238-245
    • Bartek, J.1    Lukas, J.2
  • 3
    • 33646117239 scopus 로고    scopus 로고
    • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
    • Bekker-Jensen, S. et al. (2006) Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Biol. Chem., 173, 195-206.
    • (2006) J. Biol. Chem. , vol.173 , pp. 195-206
    • Bekker-Jensen, S.1
  • 4
    • 71949083551 scopus 로고    scopus 로고
    • XPF-ERCC1 participates in the Fanconi Anemia pathway of cross-link repair
    • Bhagwat, N. et al. (2009) XPF-ERCC1 participates in the Fanconi Anemia pathway of cross-link repair. Mol. Cell. Biol., 29, 6427-6437.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 6427-6437
    • Bhagwat, N.1
  • 5
    • 33847784791 scopus 로고    scopus 로고
    • Multiple levels of cyclin specificity in cell-cycle control
    • Bloom, J. and Cross, F. R. (2007) Multiple levels of cyclin specificity in cell-cycle control. Nat. Rev. Mol. Cell Biol., 8, 149-160.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 149-160
    • Bloom, J.1    Cross, F.R.2
  • 6
    • 77950958141 scopus 로고    scopus 로고
    • 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
    • Bunting, S. F. et al. (2010) 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell, 141, 243-254.
    • (2010) Cell , vol.141 , pp. 243-254
    • Bunting, S.F.1
  • 7
    • 77955665512 scopus 로고    scopus 로고
    • Aprotein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNAdamage
    • Carlessi, L. et al. (2010)Aprotein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNAdamage. Biochim. Biophys. Acta, 1803, 1213-1223.
    • (2010) Biochim. Biophys. Acta , vol.1803 , pp. 1213-1223
    • Carlessi, L.1
  • 8
    • 58249109379 scopus 로고    scopus 로고
    • DNA damage tolerance: when it's OK to make mistakes
    • Chang, D. J. and Cimprich, K. A. (2009) DNA damage tolerance: when it's OK to make mistakes. Nat. Chem. Biol., 5, 82-90.
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 82-90
    • Chang, D.J.1    Cimprich, K.A.2
  • 9
    • 18844380444 scopus 로고    scopus 로고
    • Robustness and fragility of Boolean models for genetic regulatory networks
    • Chaves, M. et al. (2005) Robustness and fragility of Boolean models for genetic regulatory networks. J. Theor. Biol., 235, 431-449.
    • (2005) J. Theor. Biol. , vol.235 , pp. 431-449
    • Chaves, M.1
  • 10
    • 33947628597 scopus 로고    scopus 로고
    • Albert systems-level insights into cellular regulation: inferring, analysing, and modelling intracellular networks
    • Christensen, C. et al. (2007) Albert systems-level insights into cellular regulation: inferring, analysing, and modelling intracellular networks. IET Syst. Biol., 1, 61-77.
    • (2007) IET Syst. Biol. , vol.1 , pp. 61-77
    • Christensen, C.1
  • 11
    • 64149129169 scopus 로고    scopus 로고
    • UAF1 is a subunit of multiple deubiquitinating enzyme complexes
    • Cohn, M. A. et al. (2009) UAF1 is a subunit of multiple deubiquitinating enzyme complexes. J. Biol. Chem., 284, 5343-5351.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5343-5351
    • Cohn, M.A.1
  • 12
    • 79960086346 scopus 로고    scopus 로고
    • A mathematical model for DNA damage and repair
    • 2010, pii: 352603
    • Crooke, P. S. and Parl, F. F. (2010) A mathematical model for DNA damage and repair. J. Nucleic Acids., 2010, pii: 352603.
    • (2010) J. Nucleic Acids.
    • Crooke, P.S.1    Parl, F.F.2
  • 13
    • 79251624412 scopus 로고    scopus 로고
    • Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia
    • Crossan, G. P. et al. (2011) Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nat. Genet., 43, 147-154.
    • (2011) Nat. Genet. , vol.43 , pp. 147-154
    • Crossan, G.P.1
  • 14
    • 77952600845 scopus 로고    scopus 로고
    • Susceptibility pathways in Fanconi's Anemia and breast cancer
    • D'Andrea, A. (2010) Susceptibility pathways in Fanconi's Anemia and breast cancer. N. Engl. J. Med., 362, 1909-1919.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1909-1919
    • D'Andrea, A.1
  • 15
    • 45849093636 scopus 로고    scopus 로고
    • Boolean network model predicts cell cycle sequence of fission yeast
    • Davidich, M. I. and Bornholdt, S. (2008) Boolean network model predicts cell cycle sequence of fission yeast. PLoS One, 3, e1672.
    • (2008) PLoS One , vol.3
    • Davidich, M.I.1    Bornholdt, S.2
  • 16
    • 67650500593 scopus 로고    scopus 로고
    • The genetic and molecular basis of Fanconi anemia
    • de Winter, J. P. and Joenje, H. (2009) The genetic and molecular basis of Fanconi anemia. Mutat. Res., 668, 11-19.
    • (2009) Mutat. Res. , vol.668 , pp. 11-19
    • de Winter, J.P.1    Joenje, H.2
  • 17
    • 77749334700 scopus 로고    scopus 로고
    • Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX
    • Douglas, P. et al. (2010) Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. Mol. Cell. Biol., 30, 1368-1381.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 1368-1381
    • Douglas, P.1
  • 18
    • 33747874092 scopus 로고    scopus 로고
    • Dynamical analysis of a generic Boolean model for the control of the mammalian cell cycle
    • Fauré, A. et al. (2006) Dynamical analysis of a generic Boolean model for the control of the mammalian cell cycle. Bioinformatics, 22, e124-e131.
    • (2006) Bioinformatics , vol.22
    • Fauré, A.1
  • 19
    • 0030925222 scopus 로고    scopus 로고
    • Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependentmanner
    • Fiscella, M. et al. (1997) Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependentmanner. Proc. Natl Acad. Sci. USA, 94, 6048-6053.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 6048-6053
    • Fiscella, M.1
  • 20
    • 29444454665 scopus 로고    scopus 로고
    • Ubiquitinated proliferating cell nuclear antigen activates translation DNA polymerases eta and REV1
    • Garg, P. and Burgers, P. M. (2005) Ubiquitinated proliferating cell nuclear antigen activates translation DNA polymerases eta and REV1. Proc. Natl Acad. Sci. USA, 102, 18361-18366.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 18361-18366
    • Garg, P.1    Burgers, P.M.2
  • 21
    • 55849133052 scopus 로고    scopus 로고
    • Remodeling of DNA replication structures by the branch point translocase FANCM
    • Gari, K. et al. (2008) Remodeling of DNA replication structures by the branch point translocase FANCM. Proc. Natl Acad. Sci. USA, 104, 16107-16112.
    • (2008) Proc. Natl Acad. Sci. USA , vol.104 , pp. 16107-16112
    • Gari, K.1
  • 22
    • 75949092280 scopus 로고    scopus 로고
    • BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control
    • Gong, Z. et al. (2010) BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Mol. Cell, 37, 438-446.
    • (2010) Mol. Cell , vol.37 , pp. 438-446
    • Gong, Z.1
  • 23
    • 33750206776 scopus 로고    scopus 로고
    • The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNAcrosslinks into double-strands breaks
    • Hanada, K. et al. (2006) The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNAcrosslinks into double-strands breaks. EMBO J., 25, 4921-4932.
    • (2006) EMBO J , vol.25 , pp. 4921-4932
    • Hanada, K.1
  • 24
    • 0031985201 scopus 로고    scopus 로고
    • DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function
    • Heinrich, M. C. et al. (1998) DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function. Blood, 91, 275-287.
    • (1998) Blood , vol.91 , pp. 275-287
    • Heinrich, M.C.1
  • 25
    • 13444270410 scopus 로고    scopus 로고
    • Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM
    • Hirano, S. et al. (2005) Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J., 24, 418-427.
    • (2005) EMBO J , vol.24 , pp. 418-427
    • Hirano, S.1
  • 26
    • 33646196532 scopus 로고    scopus 로고
    • Regulation of DNA repair by ubiquitylation
    • Huang, T. T. and D'Andrea, A. D. (2006) Regulation of DNA repair by ubiquitylation. Nat. Rev. Mol. Cell Biol., 7, 323-334.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 323-334
    • Huang, T.T.1    D'Andrea, A.D.2
  • 27
    • 77955841149 scopus 로고    scopus 로고
    • Collaboration and competition between DNA doublestrand break repair pathways
    • Kass, E. M. and Jasin, M. (2010) Collaboration and competition between DNA doublestrand break repair pathways. FEBS Lett., 584, 3703-3708.
    • (2010) FEBS Lett , vol.584 , pp. 3703-3708
    • Kass, E.M.1    Jasin, M.2
  • 28
    • 77955889790 scopus 로고    scopus 로고
    • Expanded roles of the Fanconi anemia pathway in preserving genomic stability
    • Kee, Y. and D'Andrea, A. D. (2010) Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev., 24, 1680-1694.
    • (2010) Genes Dev , vol.24 , pp. 1680-1694
    • Kee, Y.1    D'Andrea, A.D.2
  • 29
    • 46749106037 scopus 로고    scopus 로고
    • Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24
    • Kim, J. M. et al. (2008) Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24. Blood, 111, 5215-5222.
    • (2008) Blood , vol.111 , pp. 5215-5222
    • Kim, J.M.1
  • 30
    • 79251611165 scopus 로고    scopus 로고
    • Mutations of the SLX4 gene in Fanconi anemia
    • Kim, Y. et al. (2011) Mutations of the SLX4 gene in Fanconi anemia. Nat. Genet., 43, 142-143.
    • (2011) Nat. Genet. , vol.43 , pp. 142-143
    • Kim, Y.1
  • 31
    • 0034714401 scopus 로고    scopus 로고
    • Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease
    • Kuraoka, I. et al. (2000) Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease. J. Biol. Chem., 275, 26632-26636.
    • (2000) J. Biol. Chem. , vol.275 , pp. 26632-26636
    • Kuraoka, I.1
  • 32
    • 0016720309 scopus 로고
    • Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia
    • Latt, S. A. et al. (1975) Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia. Proc. Natl Acad. Sci. USA, 72, 4066-4070.
    • (1975) Proc. Natl Acad. Sci. USA , vol.72 , pp. 4066-4070
    • Latt, S.A.1
  • 33
    • 77954274685 scopus 로고    scopus 로고
    • Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
    • MacKay, C. et al. (2010) Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell, 142, 65-76.
    • (2010) Cell , vol.142 , pp. 65-76
    • MacKay, C.1
  • 34
    • 33646345600 scopus 로고    scopus 로고
    • A network model for the control of the differentiation process in Th cells
    • Mendoza, L. (2006) A network model for the control of the differentiation process in Th cells. BioSystems, 84, 101-114.
    • (2006) BioSystems , vol.84 , pp. 101-114
    • Mendoza, L.1
  • 35
    • 78149362061 scopus 로고    scopus 로고
    • A robust model to describe the differentiation of T-helper cells
    • Mendoza, L. and Pardo, F. (2010) A robust model to describe the differentiation of T-helper cells. Theory Biosci., 129, 283-293.
    • (2010) Theory Biosci , vol.129 , pp. 283-293
    • Mendoza, L.1    Pardo, F.2
  • 36
    • 0032879544 scopus 로고    scopus 로고
    • Genetic control of flower morphogenesis in Arabidopsis thaliana: a logical analysis
    • Mendoza, L. et al. (1999) Genetic control of flower morphogenesis in Arabidopsis thaliana: a logical analysis. Bioinformatics, 15, 593-606.
    • (1999) Bioinformatics , vol.15 , pp. 593-606
    • Mendoza, L.1
  • 37
    • 77952851181 scopus 로고    scopus 로고
    • BoolNet-an R package for generation, reconstruction and analysis of Boolean networks
    • Müssel, C. et al. (2010) BoolNet-an R package for generation, reconstruction and analysis of Boolean networks. Bioinformatics, 26, 1378-1380.
    • (2010) Bioinformatics , vol.26 , pp. 1378-1380
    • Müssel, C.1
  • 38
    • 67650403821 scopus 로고    scopus 로고
    • Genotype-phenotype correlations in Fanconi anemia
    • Neveling, K. et al. (2009) Genotype-phenotype correlations in Fanconi anemia. Mutat. Res., 668, 73-91.
    • (2009) Mutat. Res. , vol.668 , pp. 73-91
    • Neveling, K.1
  • 39
    • 55849091416 scopus 로고    scopus 로고
    • Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells
    • Niimi, A. et al. (2008) Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proc. Natl Acad. Sci. USA, 105, 16125-16130.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 16125-16130
    • Niimi, A.1
  • 40
    • 13244291457 scopus 로고    scopus 로고
    • The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
    • Nijman, S. M. B. et al. (2005) The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol. Cell, 17, 331-339.
    • (2005) Mol. Cell , vol.17 , pp. 331-339
    • Nijman, S.M.B.1
  • 41
    • 77953879925 scopus 로고    scopus 로고
    • Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway
    • Pace, P. et al. (2010) Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway. Science, 329, 219-223.
    • (2010) Science , vol.329 , pp. 219-223
    • Pace, P.1
  • 42
    • 69249216420 scopus 로고    scopus 로고
    • MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair
    • Roques, C. et al. (2009) MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair. EMBO J., 28, 2400-2413.
    • (2009) EMBO J , vol.28 , pp. 2400-2413
    • Roques, C.1
  • 43
    • 0347624597 scopus 로고    scopus 로고
    • Repair kinetics of genomic interstrand DNAcrosslinks: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway
    • Rothfuss, A. and Grompe, M. (2004) Repair kinetics of genomic interstrand DNAcrosslinks: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol. Cell. Biol., 24, 123-134.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 123-134
    • Rothfuss, A.1    Grompe, M.2
  • 44
    • 33744950933 scopus 로고    scopus 로고
    • Recombination mediator and Rad51 targeting activities of a Human BRCA2 polypeptide
    • San Filippo, J. et al. (2006) Recombination mediator and Rad51 targeting activities of a Human BRCA2 polypeptide. J. Biol. Chem., 281, 11649-11657.
    • (2006) J. Biol. Chem. , vol.281 , pp. 11649-11657
    • San Filippo, J.1
  • 45
    • 77954286076 scopus 로고    scopus 로고
    • A genetic screen identifies FAN1, a Fanconi anemiaassociated nuclease necessary for DNA interstrand crosslink repair
    • Smogorzewska, A. et al. (2010) A genetic screen identifies FAN1, a Fanconi anemiaassociated nuclease necessary for DNA interstrand crosslink repair. Mol. Cell, 39, 36-47.
    • (2010) Mol. Cell , vol.39 , pp. 36-47
    • Smogorzewska, A.1
  • 46
    • 0032999346 scopus 로고    scopus 로고
    • Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells
    • Sonoda, E. et al. (1999) Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells. Mol. Cell. Biol., 19, 5166-5169.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5166-5169
    • Sonoda, E.1
  • 47
    • 0035083172 scopus 로고    scopus 로고
    • Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs
    • Takata, M. et al. (2001) Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol. Cell. Biol., 21, 2858-2866.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2858-2866
    • Takata, M.1
  • 48
    • 77951747926 scopus 로고    scopus 로고
    • Mutation of the RAD51C gene in a Fanconi anemia-like disorder
    • Vaz, F. et al. (2010) Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat. Genet., 42, 406-411.
    • (2010) Nat. Genet. , vol.42 , pp. 406-411
    • Vaz, F.1
  • 49
    • 0035688468 scopus 로고    scopus 로고
    • The chinease hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous chromatid exchange
    • Wilson, J. B. et al. (2001) The chinease hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous chromatid exchange. Carcinogenesis, 22, 1939-1946.
    • (2001) Carcinogenesis , vol.22 , pp. 1939-1946
    • Wilson, J.B.1
  • 50
    • 77949531986 scopus 로고    scopus 로고
    • A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach
    • Wu, M. et al. (2009) A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach. PLoS One, 4, e8040.
    • (2009) PLoS One , vol.4
    • Wu, M.1
  • 51
    • 33846601829 scopus 로고    scopus 로고
    • Fanconi anemia is associated with a defect in the BRCA2 partner PALB2
    • Xia, B. et al. (2007) Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat. Genet., 39, 159-161.
    • (2007) Nat. Genet. , vol.39 , pp. 159-161
    • Xia, B.1
  • 52
    • 55849100058 scopus 로고    scopus 로고
    • Network model of survival signaling in large granular lymphocyte leukemia
    • Zhang, R. et al. (2009a) Network model of survival signaling in large granular lymphocyte leukemia. Proc. Natl Acad. Sci. USA, 105, 16308-16313.
    • (2009) Proc. Natl Acad. Sci. USA , vol.105 , pp. 16308-16313
    • Zhang, R.1
  • 53
    • 62549115236 scopus 로고    scopus 로고
    • PALB2 links BRCA1 and BRCA2 in the DNA-damage response
    • Zhang, F. et al. (2009b) PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr. Biol., 19, 524-529.
    • (2009) Curr. Biol. , vol.19 , pp. 524-529
    • Zhang, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.