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Volumn 17, Issue 3, 1997, Pages 1522-1534

Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; NUCLEAR FACTOR; TRANSCRIPTION FACTOR;

EID: 0031034051     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.3.1522     Document Type: Article
Times cited : (110)

References (71)
  • 1
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis clement recognized by a TPA-modulated trans-acting factor
    • Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis clement recognized by a TPA-modulated trans-acting factor. Cell 49:729-739.
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 2
    • 0029080794 scopus 로고
    • Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: Regulation upon CD16 ligand binding
    • Aramburu, J., L. Azzoni, A. Rao, and B. Perussia. 1995. Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding. J. Exp. Med. 182:801-810.
    • (1995) J. Exp. Med. , vol.182 , pp. 801-810
    • Aramburu, J.1    Azzoni, L.2    Rao, A.3    Perussia, B.4
  • 3
    • 85035187756 scopus 로고    scopus 로고
    • Aune, T., and R. A. Flavell. Unpublished data
    • Aune, T., and R. A. Flavell. Unpublished data.
  • 6
    • 0026781801 scopus 로고
    • Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major
    • Bretscher, P. A., G. Wei, J. N. Menon, and H. Bielefeldt-Ohmann. 1992. Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. Science 257:539-542.
    • (1992) Science , vol.257 , pp. 539-542
    • Bretscher, P.A.1    Wei, G.2    Menon, J.N.3    Bielefeldt-Ohmann, H.4
  • 8
    • 0027390139 scopus 로고
    • Molecular basis for developmental changes in interleukin-2 gene inducibility
    • Chen, D., and E. V. Rothenberg. 1993. Molecular basis for developmental changes in interleukin-2 gene inducibility. Mol. Cell. Biol. 13:228-237.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 228-237
    • Chen, D.1    Rothenberg, E.V.2
  • 9
    • 0028450096 scopus 로고
    • Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4
    • Choi, M. S. K., R. D. Brines, M. J. Holman, and G. G. B. Klaus. 1994. Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. Immunity 1:179-187.
    • (1994) Immunity , vol.1 , pp. 179-187
    • Choi, M.S.K.1    Brines, R.D.2    Holman, M.J.3    Klaus, G.G.B.4
  • 11
    • 0026643141 scopus 로고
    • Identification of calcineurin as a key signaling enzyme in T cell activation
    • Clipstone, N. A., and G. R. Crabtree. 1992. Identification of calcineurin as a key signaling enzyme in T cell activation. Nature 357:695-697.
    • (1992) Nature , vol.357 , pp. 695-697
    • Clipstone, N.A.1    Crabtree, G.R.2
  • 13
    • 0028316562 scopus 로고
    • Naive versus memory CD4 T cell response to antigen
    • Croft, M., L. M. Bradley, and S. L. Swain. 1994. Naive versus memory CD4 T cell response to antigen. J. Immunol. 152:2675-2685.
    • (1994) J. Immunol. , vol.152 , pp. 2675-2685
    • Croft, M.1    Bradley, L.M.2    Swain, S.L.3
  • 14
  • 15
    • 0024833664 scopus 로고
    • Cyclosporin a specifically inhibits function of nuclear proteins involved in T cell activation
    • Emmel, E. A., C. L. Verweij, D. B. Durand, K. M. Higgins, E. Lacy, and G. R. Crabtree. 1989. Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. Science 246:1617-1620.
    • (1989) Science , vol.246 , pp. 1617-1620
    • Emmel, E.A.1    Verweij, C.L.2    Durand, D.B.3    Higgins, K.M.4    Lacy, E.5    Crabtree, G.R.6
  • 16
    • 0025084605 scopus 로고
    • Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor
    • Fiering, S., J. P. Northrop, G. P. Nolan, P. S. Mattila, G. R. Crabtree, and L. A. Herzenberg. 1990. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes Dev. 4:1823-1834.
    • (1990) Genes Dev. , vol.4 , pp. 1823-1834
    • Fiering, S.1    Northrop, J.P.2    Nolan, G.P.3    Mattila, P.S.4    Crabtree, G.R.5    Herzenberg, L.A.6
  • 17
    • 0025871394 scopus 로고
    • Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A
    • Flanagan, W. F., B. Corthesy, R. J. Bram, and G. R. Crabtree. 1991. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 352:803-807.
    • (1991) Nature , vol.352 , pp. 803-807
    • Flanagan, W.F.1    Corthesy, B.2    Bram, R.J.3    Crabtree, G.R.4
  • 19
    • 0024444165 scopus 로고
    • B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells
    • Freeman, G. J., A. S. Freedman, J. M. Segil, G. Lee, J. L. Whitman, and L. M. Nadler. 1989. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143:2714-2722.
    • (1989) J. Immunol. , vol.143 , pp. 2714-2722
    • Freeman, G.J.1    Freedman, A.S.2    Segil, J.M.3    Lee, G.4    Whitman, J.L.5    Nadler, L.M.6
  • 20
    • 0018174365 scopus 로고
    • T cell growth factor: Parameters of production and quantitative microassay for activity
    • Gillis, S., M. N. Ferm, and K. A. Smith. 1978. T cell growth factor: parameters of production and quantitative microassay for activity. J. Immunol. 120:1109-1113.
    • (1978) J. Immunol. , vol.120 , pp. 1109-1113
    • Gillis, S.1    Ferm, M.N.2    Smith, K.A.3
  • 21
    • 0025967751 scopus 로고
    • Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB
    • Gonzalez, G. A., P. Menzel, J. Leonard, W. H. Fischer, and M. Montminy. 1991. Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol. Cell. Biol. 11:1306-1312.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1306-1312
    • Gonzalez, G.A.1    Menzel, P.2    Leonard, J.3    Fischer, W.H.4    Montminy, M.5
  • 22
    • 0029125831 scopus 로고
    • NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity
    • Ho, S. N., D. J. Thomas, L. A. Timmerman, X. Li, V. Francke, and G. R. Crabtree. 1995. NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity. J. Biol. Chem. 270:19898-19907.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19898-19907
    • Ho, S.N.1    Thomas, D.J.2    Timmerman, L.A.3    Li, X.4    Francke, V.5    Crabtree, G.R.6
  • 24
    • 0029053852 scopus 로고
    • Isolation of two new members of the NFAT gene family and functional characterization of the NFAT proteins
    • Hoey, T., Y.-L. Sun, K. Williamson, and X. Xiang. 1995. Isolation of two new members of the NFAT gene family and functional characterization of the NFAT proteins. Immunity 2:461-472.
    • (1995) Immunity , vol.2 , pp. 461-472
    • Hoey, T.1    Sun, Y.-L.2    Williamson, K.3    Xiang, X.4
  • 27
    • 0027491776 scopus 로고
    • The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
    • Jain, J., P. G. McCaffrey, A. Miner, T. K. Kerppola, J. N. Lambert, G. L. Verdine, T. Curram, and A. Rao. 1993. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365:352-355.
    • (1993) Nature , vol.365 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, A.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curram, T.7    Rao, A.8
  • 28
    • 0026596383 scopus 로고
    • Nuclear factor of activated T cells contains Fos and Jun
    • Jain, J., P. G. McCaffrey, V. E. Valge-Archer, and A. Rao. 1992. Nuclear factor of activated T cells contains Fos and Jun. Nature 356:801-804.
    • (1992) Nature , vol.356 , pp. 801-804
    • Jain, J.1    McCaffrey, P.G.2    Valge-Archer, V.E.3    Rao, A.4
  • 29
    • 0023143676 scopus 로고
    • Antigen presentation by chemical modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • Jenkins, M. K., and R. H. Schwartz. 1987. Antigen presentation by chemical modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 165:302.
    • (1987) J. Exp. Med. , vol.165 , pp. 302
    • Jenkins, M.K.1    Schwartz, R.H.2
  • 30
    • 0027788043 scopus 로고
    • The relationship of IL-4 and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells
    • Kamogawa, Y., L.-A. E. Minasi, S. Carding, K. Bottomly, and R. A. Flavell. 1993. The relationship of IL-4 and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells. Cell 75:985-995.
    • (1993) Cell , vol.75 , pp. 985-995
    • Kamogawa, Y.1    Minasi, L.-A.E.2    Carding, S.3    Bottomly, K.4    Flavell, R.A.5
  • 31
    • 0024444304 scopus 로고
    • Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restrictcd antigen receptor
    • Kaye, J., M.-L. Hsu, M.-E. Sauron, S. C. Jameson, N. R. J. Gascoigne, and S. M. Hedrick. 1989. Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restrictcd antigen receptor. Nature 341:746-749.
    • (1989) Nature , vol.341 , pp. 746-749
    • Kaye, J.1    Hsu, M.-L.2    Sauron, M.-E.3    Jameson, S.C.4    Gascoigne, N.R.J.5    Hedrick, S.M.6
  • 32
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo, V. K., M. Prabhu Das, J. A. Brown, A. M. Ranger, S. S. Zamvil, R. A. Sobel, H. L. Weiner, N. Nabavi, and L. H. Glimcher. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80:707-718.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Prabhu Das, M.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6    Weiner, H.L.7    Nabavi, N.8    Glimcher, L.H.9
  • 33
    • 0023611441 scopus 로고
    • Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
    • Lee, W., P. Mitchell, and R. Tjian. 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49:741-752.
    • (1987) Cell , vol.49 , pp. 741-752
    • Lee, W.1    Mitchell, P.2    Tjian, R.3
  • 34
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitrol: IL-2 and IL-4 are required for in vitro generation of IL-4 producing cells
    • Le Gros, G., S. Z. Ben-Sasson, R. Seder, F. D. Finkelman, and W. E. Paul. 1990. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitrol: IL-2 and IL-4 are required for in vitro generation of IL-4 producing cells. J. Exp. Med. 172:921-929.
    • (1990) J. Exp. Med. , vol.172 , pp. 921-929
    • Le Gros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkelman, F.D.4    Paul, W.E.5
  • 35
    • 0028900297 scopus 로고
    • Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
    • Lenschow, D. J., S. C. Ho, H. Sattar, L. Rhee, G. Gray, N. Nabavi, K. C. Herold, and J. A. Bluestone. 1995. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J. Exp. Med. 181:1145-1155.
    • (1995) J. Exp. Med. , vol.181 , pp. 1145-1155
    • Lenschow, D.J.1    Ho, S.C.2    Sattar, H.3    Rhee, L.4    Gray, G.5    Nabavi, N.6    Herold, K.C.7    Bluestone, J.A.8
  • 36
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
    • Linsley, P. S., W. Brady, L. Grosmaire, A. Aruffo, N. K. Damle, and J. A. Ledbetter. 1991. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J. Exp. Med. 173:721-730.
    • (1991) J. Exp. Med. , vol.173 , pp. 721-730
    • Linsley, P.S.1    Brady, W.2    Grosmaire, L.3    Aruffo, A.4    Damle, N.K.5    Ledbetter, J.A.6
  • 37
    • 0027403299 scopus 로고
    • The role of the CD28 receptor during T cell responses
    • Linsley, P. S., and J. A. Ledbetter. 1993. The role of the CD28 receptor during T cell responses. Annu. Rev. Immunol. 11:191-212.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 191-212
    • Linsley, P.S.1    Ledbetter, J.A.2
  • 38
    • 0028930843 scopus 로고
    • NFATx, a novel member of the nuclear factor of activated-T-cell family that is predominantly expressed in thymus
    • Masuda, E. S., Y. Naito, H. Tokumitsu, D. Campbell, F. Saito, C. Hannum, K.-I. Arai, and N. Arai. 1995. NFATx, a novel member of the nuclear factor of activated-T-cell family that is predominantly expressed in thymus. Mol. Cell. Biol. 15:2697-2707.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2697-2707
    • Masuda, E.S.1    Naito, Y.2    Tokumitsu, H.3    Campbell, D.4    Saito, F.5    Hannum, C.6    Arai, K.-I.7    Arai, N.8
  • 40
    • 0023198109 scopus 로고
    • Binding of nuclear protein to the cyclic-AMP response element of the somatostatin gene
    • Montminy, M. R., and L. M. Bilezikijan. 1986. Binding of nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 328:175-178.
    • (1986) Nature , vol.328 , pp. 175-178
    • Montminy, M.R.1    Bilezikijan, L.M.2
  • 41
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 42
    • 0024327899 scopus 로고
    • Clonal expansion vs functional clonal inactivation: A costimulatory pathway determines the outcome of T cell receptor occupancy
    • Mueller, D. L., M. K. Jenkins, and R. H. Schwartz. 1989. Clonal expansion vs functional clonal inactivation: a costimulatory pathway determines the outcome of T cell receptor occupancy. Annu. Rev. Immunol. 7:445-480.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 43
    • 85035185974 scopus 로고    scopus 로고
    • Nakamura, T. Unpublished data
    • Nakamura, T. Unpublished data.
  • 44
    • 0028114712 scopus 로고
    • Functional roles and signal-induced modulation of proteins recognizing the conserved TCATTT-containing promoter elements in the murine IL-5 and GM-CSF genes in T lymphocytes
    • Naora, H., B. H. van Leeuwen, P. F. Bourke, and I. G. Young. 1994. Functional roles and signal-induced modulation of proteins recognizing the conserved TCATTT-containing promoter elements in the murine IL-5 and GM-CSF genes in T lymphocytes. J. Immunol. 153:3466-3475.
    • (1994) J. Immunol. , vol.153 , pp. 3466-3475
    • Naora, H.1    Van Leeuwen, B.H.2    Bourke, P.F.3    Young, I.G.4
  • 45
    • 0028361589 scopus 로고
    • NF-AT components define a family of transcription factors targeted in T-cell activation
    • Northrop, J. P., S. N. Ho, L. Chen, D. J. Thomas, G. P. Nolan, A. Admon, and G. R. Crabtree. 1994. NF-AT components define a family of transcription factors targeted in T-cell activation. Nature 369:497-502.
    • (1994) Nature , vol.369 , pp. 497-502
    • Northrop, J.P.1    Ho, S.N.2    Chen, L.3    Thomas, D.J.4    Nolan, G.P.5    Admon, A.6    Crabtree, G.R.7
  • 46
    • 0027518679 scopus 로고
    • Characterization of nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT)
    • Northrop, J. P., K. S. Ullman, and G. R. Crabtree. 1993. Characterization of nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT). J. Biol. Chem. 268:2917-2923.
    • (1993) J. Biol. Chem. , vol.268 , pp. 2917-2923
    • Northrop, J.P.1    Ullman, K.S.2    Crabtree, G.R.3
  • 47
    • 0026632557 scopus 로고
    • FK506 and cyclosporin A-sensitive activation of the interleukin-2 promoter by calcineurin
    • O'Keefe, S. J., J. Tamura, R. L. Kincaid, M. J. Tocci, and E. A. O'Neill. 1992. FK506 and cyclosporin A-sensitive activation of the interleukin-2 promoter by calcineurin. Nature 357:692-694.
    • (1992) Nature , vol.357 , pp. 692-694
    • O'Keefe, S.J.1    Tamura, J.2    Kincaid, R.L.3    Tocci, M.J.4    O'Neill, E.A.5
  • 48
    • 0028179006 scopus 로고
    • Lymphocyte response and cytokines
    • Paul, W. E., and R. A. Seder. 1994. Lymphocyte response and cytokines. Cell 76:241-251.
    • (1994) Cell , vol.76 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2
  • 49
    • 0027364319 scopus 로고
    • Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells
    • Penix, L., W. M. Weaver, Y. Pang, H. A. Young, and C. B. Wilson. 1993. Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells. J. Exp. Med. 178:1483-1496.
    • (1993) J. Exp. Med. , vol.178 , pp. 1483-1496
    • Penix, L.1    Weaver, W.M.2    Pang, Y.3    Young, H.A.4    Wilson, C.B.5
  • 51
    • 0028300431 scopus 로고
    • NF-ATp: A transcription factor required for the co-ordinate induction of several cytokine genes
    • Rao, A. 1994. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunol. Today 15:274-281.
    • (1994) Immunol. Today , vol.15 , pp. 274-281
    • Rao, A.1
  • 52
    • 85035183361 scopus 로고    scopus 로고
    • Reprogramming the signaling requirement for AP-1 activation during differentiation of precursor CD4+ T cells to effector Th1 and Th2 cells
    • in press
    • Rincón, M., B. Dérijard, C.-W. Chow, R. J. Davis, and R. A. Flavell. Reprogramming the signaling requirement for AP-1 activation during differentiation of precursor CD4+ T cells to effector Th1 and Th2 cells. Genes Funct., in press.
    • Genes Funct.
    • Rincón, M.1    Dérijard, B.2    Chow, C.-W.3    Davis, R.J.4    Flavell, R.A.5
  • 53
    • 0027936441 scopus 로고
    • AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes
    • Rincón, M., and R. A. Flavell. 1994. AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J. 13:4370-4381.
    • (1994) EMBO J. , vol.13 , pp. 4370-4381
    • Rincón, M.1    Flavell, R.A.2
  • 54
    • 0030059827 scopus 로고    scopus 로고
    • Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells
    • Rincón, M., and R. A. Flavell. 1996. Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells. Mol. Cell. Biol. 16:1074-1084.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1074-1084
    • Rincón, M.1    Flavell, R.A.2
  • 55
    • 0028157768 scopus 로고
    • A common factor regulates both Th1- and Th2-specific cytokine gene expression
    • Rooney, J. W., M. R. Hodge, P. G. McCaffrey, A. Rao, and L. H. Glimcher. 1994. A common factor regulates both Th1- and Th2-specific cytokine gene expression. EMBO J. 13:625-633.
    • (1994) EMBO J. , vol.13 , pp. 625-633
    • Rooney, J.W.1    Hodge, M.R.2    McCaffrey, P.G.3    Rao, A.4    Glimcher, L.H.5
  • 56
    • 0029030775 scopus 로고
    • Coordinate and cooperative roles for NFAT and AP-1 in the regulation of murine IL-4 gene
    • Rooney, J. W., T. Hoey, and L. H. Glimcher. 1995. Coordinate and cooperative roles for NFAT and AP-1 in the regulation of murine IL-4 gene. Immunity 2:473-483.
    • (1995) Immunity , vol.2 , pp. 473-483
    • Rooney, J.W.1    Hoey, T.2    Glimcher, L.H.3
  • 57
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini'-extracts prepared from a small number of cells
    • Schreiber, E., P. Matthias, M. M. Müller, and W. Shaffner. 1989. Rapid detection of octamer binding proteins with 'mini'-extracts prepared from a small number of cells. Nucleic Acids Res. 17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Müller, M.M.3    Shaffner, W.4
  • 58
    • 0026575932 scopus 로고
    • The mechanism of action of cyclosporin a and K506
    • Schreiber, S. L., and G. R. Crabtree. 1992. The mechanism of action of cyclosporin A and K506. Immunol. Today 13:136-142.
    • (1992) Immunol. Today , vol.13 , pp. 136-142
    • Schreiber, S.L.1    Crabtree, G.R.2
  • 59
    • 0027491655 scopus 로고
    • + T cells to enhance priming for IFNγ production and diminish IL-4 inhibition of such priming
    • + T cells to enhance priming for IFNγ production and diminish IL-4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90:10188-10192.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 60
    • 0024330265 scopus 로고
    • Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes
    • Serfling, E., R. Bsrthelmäs, I. Pfeuffer, B. Schenk, S. Zarius, R. Swoboda, F. Mercurio, and M. Karin. 1989. Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes. EMBO J. 8:465-473.
    • (1989) EMBO J. , vol.8 , pp. 465-473
    • Serfling, E.1    Bsrthelmäs, R.2    Pfeuffer, I.3    Schenk, B.4    Zarius, S.5    Swoboda, R.6    Mercurio, F.7    Karin, M.8
  • 61
    • 0023821516 scopus 로고
    • Identification of a putative regulator of early T cell activation genes
    • Shaw, J.-P., P. J. Utz, D. B. Durand, J. J. Toole, E. A. Emmel, and G. R. Crabtree. 1988. Identification of a putative regulator of early T cell activation genes. Science 241:202-205.
    • (1988) Science , vol.241 , pp. 202-205
    • Shaw, J.-P.1    Utz, P.J.2    Durand, D.B.3    Toole, J.J.4    Emmel, E.A.5    Crabtree, G.R.6
  • 62
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727-736.
    • (1994) Cell , vol.77 , pp. 727-736
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 63
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145:3796-3806.
    • (1990) J. Immunol. , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 64
    • 0027305687 scopus 로고
    • Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: Roles for NF-Y and NF-ATc
    • Szabo, S. J., J. S. Gold, T. L. Murphy, and K. M. Murphy. 1993. Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. Mol. Cell. Biol. 13:4793-4805.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4793-4805
    • Szabo, S.J.1    Gold, J.S.2    Murphy, T.L.3    Murphy, K.M.4
  • 65
    • 0029008237 scopus 로고
    • Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element
    • Tara, D., D. L. Weiss, and M. A. Brown. 1995. Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element. J. Immunol. 154:4592-4602.
    • (1995) J. Immunol. , vol.154 , pp. 4592-4602
    • Tara, D.1    Weiss, D.L.2    Brown, M.A.3
  • 67
    • 0026550073 scopus 로고
    • Human T cell activation through the activation-inducer molecule/CD69 enhances the activity of transcription factor AP-1
    • Tugores, A., M. A. Alonso, F. Sánchez-Madrid, and M. O. de Landázuri. 1992. Human T cell activation through the activation-inducer molecule/CD69 enhances the activity of transcription factor AP-1. J. Immunol. 148: 2300-2306.
    • (1992) J. Immunol. , vol.148 , pp. 2300-2306
    • Tugores, A.1    Alonso, M.A.2    Sánchez-Madrid, F.3    De Landázuri, M.O.4
  • 69
    • 0025127909 scopus 로고
    • Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor
    • Verweij, C. L., C. Guidos, and G. R. Crabtree. 1990. Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor. J. Biol. Chem. 265:15788-15795.
    • (1990) J. Biol. Chem. , vol.265 , pp. 15788-15795
    • Verweij, C.L.1    Guidos, C.2    Crabtree, G.R.3
  • 71
    • 0027315713 scopus 로고
    • Comparative analysis of NFAT (nuclear factor of activated T cells) complex in human T and B lymphocytes
    • Yaseen, N. R., A. L. Maizel, F. Wang, and S. Sharma. 1993. Comparative analysis of NFAT (nuclear factor of activated T cells) complex in human T and B lymphocytes. J. Biol. Chem. 268:14285-14293.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14285-14293
    • Yaseen, N.R.1    Maizel, A.L.2    Wang, F.3    Sharma, S.4


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