A Loss-of-Function Screen for Phosphatases that Regulate Neurite Outgrowth Identifies PTPN12 as a Negative Regulator of TrkB Tyrosine Phosphorylation

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Ambjørn, Malene ^a   Dubreuil, Véronique ^b   Miozzo, Federico ^b   Nigon, Fabienne ^b   Møller, Bente ^a   Issazadeh Navikas, Shohreh ^a   Berg, Jacob ^c   Lees, Michael ^a   Sap, Jan ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CRK ASSOCIATED SUBSTRATE PROTEIN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; NEUROTROPHIN; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 12; PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL LINE; CRK-ASSOCIATED SUBSTRATE PROTEIN; DRUG EVALUATION, PRECLINICAL; FOCAL ADHESION KINASE 1; GENE KNOCKDOWN TECHNIQUES; HUMANS; NEURITES; NEURONS; PHENOTYPE; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 12; RECEPTOR, TRKB; REPRODUCIBILITY OF RESULTS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRETINOIN;

EID: 84878994412     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065371     Document Type: Article

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