-
1
-
-
0035089779
-
Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways
-
Ai S, Kuzuya M, Koike T, Asai T, Kanda S, Maeda K, Shibata T, Iguchi A. 2001. Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways. Atherosclerosis 155:321-327.
-
(2001)
Atherosclerosis
, vol.155
, pp. 321-327
-
-
Ai, S.1
Kuzuya, M.2
Koike, T.3
Asai, T.4
Kanda, S.5
Maeda, K.6
Shibata, T.7
Iguchi, A.8
-
2
-
-
0142148219
-
Identification of Tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase
-
Amano M, Kaneko T, Maeda A, Nakayama M, Ito M, Yamauchi T, Goto H, Fukata Y, Oshiro N, Shinohara A, Iwamatsu A, Kaibuchi K. 2003. Identification of Tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase. J Neurochem 87:780-790.
-
(2003)
J Neurochem
, vol.87
, pp. 780-790
-
-
Amano, M.1
Kaneko, T.2
Maeda, A.3
Nakayama, M.4
Ito, M.5
Yamauchi, T.6
Goto, H.7
Fukata, Y.8
Oshiro, N.9
Shinohara, A.10
Iwamatsu, A.11
Kaibuchi, K.12
-
3
-
-
0347683437
-
Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neunte outgrowth in PC12 cells
-
Aoki K, Nakamura T, Matsuda M. 2004. Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neunte outgrowth in PC12 cells. J Biol Chem 279:713-719.
-
(2004)
J Biol Chem
, vol.279
, pp. 713-719
-
-
Aoki, K.1
Nakamura, T.2
Matsuda, M.3
-
4
-
-
0037033804
-
Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell-cell adhesion
-
Calautti E, Grossi M, Mammucari C, Aoyama Y, Pirro M, Ono Y, Li J, Dotto GP. 2002. Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell-cell adhesion. J Cell Biol 156(1):137-148.
-
(2002)
J Cell Biol
, vol.156
, Issue.1
, pp. 137-148
-
-
Calautti, E.1
Grossi, M.2
Mammucari, C.3
Aoyama, Y.4
Pirro, M.5
Ono, Y.6
Li, J.7
Dotto, G.P.8
-
5
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351:95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
6
-
-
0036703599
-
Rho signaling pathway targeted to promote spinal cord repair
-
Dergham P, Ellezam B, Essagian C, Avedissian H, Lubell WD, McKerracher L. 2002. Rho signaling pathway targeted to promote spinal cord repair. J Neurosci 22(15):6570-6577.
-
(2002)
J Neurosci
, vol.22
, Issue.15
, pp. 6570-6577
-
-
Dergham, P.1
Ellezam, B.2
Essagian, C.3
Avedissian, H.4
Lubell, W.D.5
McKerracher, L.6
-
7
-
-
0037443069
-
Rho kinase inhibition enhances axonal regeneration in the injured CNS
-
Fournier AE, Takizawa BT, Strittmatter SM. 2003. Rho kinase inhibition enhances axonal regeneration in the injured CNS. J Neurosci 23:1416-1423.
-
(2003)
J Neurosci
, vol.23
, pp. 1416-1423
-
-
Fournier, A.E.1
Takizawa, B.T.2
Strittmatter, S.M.3
-
9
-
-
0035900330
-
NGF induces neurite outgrowth via a decrease in phosphorylation of myosin light chain in PC12 cells
-
Fujita A, Hattori Y, Takeuchi T, Kamata Y, Hata F. 2001. NGF induces neurite outgrowth via a decrease in phosphorylation of myosin light chain in PC12 cells. Neuroreport 12:3599-3602.
-
(2001)
Neuroreport
, vol.12
, pp. 3599-3602
-
-
Fujita, A.1
Hattori, Y.2
Takeuchi, T.3
Kamata, Y.4
Hata, F.5
-
10
-
-
31544464385
-
Regulation of microtubule dynamics in 3T3 fibroblasts by Rho family GTPases
-
Grigoriev I, Borisy G, Vorobjev I. 2006. Regulation of microtubule dynamics in 3T3 fibroblasts by Rho family GTPases. Cell Motil Cytoskel 63:29-40.
-
(2006)
Cell Motil Cytoskel
, vol.63
, pp. 29-40
-
-
Grigoriev, I.1
Borisy, G.2
Vorobjev, I.3
-
11
-
-
0036795318
-
Microtubule capture: IQGAP and CLIP-170 expand the repertoire
-
Gundersen GG. 2002. Microtubule capture: IQGAP and CLIP-170 expand the repertoire. Curr Biol 12:R645-R647.
-
(2002)
Curr Biol
, vol.12
-
-
Gundersen, G.G.1
-
12
-
-
14444288533
-
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma NIE-115 cells
-
Hirose M, Ishizaki T, Watanabe N, Uehata M, Kranenburg O, Moolenaar WH, Matsumura F, Maekawa M, Bito H, Narumiya S. 1998. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma NIE-115 cells. J Cell Biol 141:1625-1636.
-
(1998)
J Cell Biol
, vol.141
, pp. 1625-1636
-
-
Hirose, M.1
Ishizaki, T.2
Watanabe, N.3
Uehata, M.4
Kranenburg, O.5
Moolenaar, W.H.6
Matsumura, F.7
Maekawa, M.8
Bito, H.9
Narumiya, S.10
-
13
-
-
32544454623
-
Myelin-associated inhibitors regulate cofilin phosphorylation and neuronal inhibition through LIM kinase and Slingshot phosphatase
-
Hsieh SH, Ferraro GB, Fournier AE. 2006. Myelin-associated inhibitors regulate cofilin phosphorylation and neuronal inhibition through LIM kinase and Slingshot phosphatase. J Neurosci 26:1006-1015.
-
(2006)
J Neurosci
, vol.26
, pp. 1006-1015
-
-
Hsieh, S.H.1
Ferraro, G.B.2
Fournier, A.E.3
-
14
-
-
0034017744
-
Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases
-
Ishizaki T, Uehata M, Tamechika I, Keel J, Nonomura K, Maekawa M, Narumiya S. 2000. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol Pharmacol 57:976-983.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 976-983
-
-
Ishizaki, T.1
Uehata, M.2
Tamechika, I.3
Keel, J.4
Nonomura, K.5
Maekawa, M.6
Narumiya, S.7
-
15
-
-
0032935495
-
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
-
Itoh K, Yoshioka K, Akedo H, Uehata M, Ishizaki T, Narumiya S. 1999. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med 5:221-225.
-
(1999)
Nat Med
, vol.5
, pp. 221-225
-
-
Itoh, K.1
Yoshioka, K.2
Akedo, H.3
Uehata, M.4
Ishizaki, T.5
Narumiya, S.6
-
16
-
-
26044447158
-
Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase
-
Kaneko T, Maeda A, Takefuji M, Aoyama H, Nakayama M, Kawabata S, Kawano Y, Iwamatsu A, Amano M, Kaibuchi K. 2005. Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase. Genes Cells 10:973-987.
-
(2005)
Genes Cells
, vol.10
, pp. 973-987
-
-
Kaneko, T.1
Maeda, A.2
Takefuji, M.3
Aoyama, H.4
Nakayama, M.5
Kawabata, S.6
Kawano, Y.7
Iwamatsu, A.8
Amano, M.9
Kaibuchi, K.10
-
17
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, et al. 1996. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273:245-248.
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukata, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
-
18
-
-
0033005291
-
The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes-possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy
-
Kuwahara K, Saito Y, Nakagawa O, Kishimoto I, Harada M, Ogawa E, Miyamoto Y, Hamanaka I, Kajiyama N, Takahashi N, et al. 1999. The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes-possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy. FEES Lett 452:314-318.
-
(1999)
FEES Lett
, vol.452
, pp. 314-318
-
-
Kuwahara, K.1
Saito, Y.2
Nakagawa, O.3
Kishimoto, I.4
Harada, M.5
Ogawa, E.6
Miyamoto, Y.7
Hamanaka, I.8
Kajiyama, N.9
Takahashi, N.10
-
19
-
-
0037326055
-
Involvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound models
-
Magdalena J, Millard TH, Etienne-Manneville S, Launay S, Warwick HK, Machesky LM. 2003. Involvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound models. Mol Biol Cell 14:670-684.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 670-684
-
-
Magdalena, J.1
Millard, T.H.2
Etienne-Manneville, S.3
Launay, S.4
Warwick, H.K.5
Machesky, L.M.6
-
20
-
-
0033772834
-
Use and properties of ROCK-specific inhibitor Y-27632
-
Narumiya S, Ishizaki T, Uehata M. 2000. Use and properties of ROCK-specific inhibitor Y-27632. Methods Enzymol 325:273-284.
-
(2000)
Methods Enzymol
, vol.325
, pp. 273-284
-
-
Narumiya, S.1
Ishizaki, T.2
Uehata, M.3
-
21
-
-
0032991828
-
Rho-kinase in human neutrophils: A role in signalling for myosin light chain phosphorylation and cell migration
-
Niggli V. 1999. Rho-kinase in human neutrophils: A role in signalling for myosin light chain phosphorylation and cell migration. FEES Lett 445:69-72.
-
(1999)
FEES Lett
, vol.445
, pp. 69-72
-
-
Niggli, V.1
-
22
-
-
0034907213
-
mDia mediates Rho-regulated formation and orientation of stable microtubules
-
Palazzo AF, Cook TA, Alberts AS, Gundersen GG. 2001. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat Cell Biol 3:723-729.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 723-729
-
-
Palazzo, A.F.1
Cook, T.A.2
Alberts, A.S.3
Gundersen, G.G.4
-
23
-
-
0034141607
-
Regulation of LPA-promoted myofibroblast contraction: Role of Rho, myosin light chain kinase, and myosin light chain phosphatase
-
Parizi M, Howard EW, Tomasek JJ. 2000. Regulation of LPA-promoted myofibroblast contraction: Role of Rho, myosin light chain kinase, and myosin light chain phosphatase. Exp Cell Res 254:210-220.
-
(2000)
Exp Cell Res
, vol.254
, pp. 210-220
-
-
Parizi, M.1
Howard, E.W.2
Tomasek, J.J.3
-
24
-
-
0035422395
-
The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9
-
Piddini E, Schmid JA, de Martin R, Dotti CG. 2001. The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9. EMBO J 20:4076-4087.
-
(2001)
EMBO J
, vol.20
, pp. 4076-4087
-
-
Piddini, E.1
Schmid, J.A.2
de Martin, R.3
Dotti, C.G.4
-
25
-
-
0038024241
-
Rocks: Multifunctional kinases in cell behaviour
-
Riento K, Ridley AJ. 2003. Rocks: Multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 4:446-456.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 446-456
-
-
Riento, K.1
Ridley, A.J.2
-
26
-
-
0033988255
-
Phosphatidylinositol 3-kinase, Cdc42, and Rac1 act downstream of Ras in integrin-dependent neurite outgrowth in N1E-115 neuroblastoma cells
-
Sarner S, Kozma R, Ahmed S, Lim L. 2000. Phosphatidylinositol 3-kinase, Cdc42, and Rac1 act downstream of Ras in integrin-dependent neurite outgrowth in N1E-115 neuroblastoma cells. Mol Cell Biol 20:158-172.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 158-172
-
-
Sarner, S.1
Kozma, R.2
Ahmed, S.3
Lim, L.4
-
27
-
-
20144379401
-
ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles
-
Shimizu Y, Thumkeo D, Keel J, Ishizaki T, Oshima H, Oshima M, Noda Y, Matsumura F, Taketo MM, Narumiya S. 2005. ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol 168:941-953.
-
(2005)
J Cell Biol
, vol.168
, pp. 941-953
-
-
Shimizu, Y.1
Thumkeo, D.2
Keel, J.3
Ishizaki, T.4
Oshima, H.5
Oshima, M.6
Noda, Y.7
Matsumura, F.8
Taketo, M.M.9
Narumiya, S.10
-
28
-
-
29144527049
-
Development of specific Rho-kinase inhibitors and their clinical application
-
Tamura M, Nakao H, Yoshizaki H, Shiratsuchi M, Shigyo H, Yamada H, Ozawa T, Totsuka J, Hidaka H. 2005. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta 1754:245-252.
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 245-252
-
-
Tamura, M.1
Nakao, H.2
Yoshizaki, H.3
Shiratsuchi, M.4
Shigyo, H.5
Yamada, H.6
Ozawa, T.7
Totsuka, J.8
Hidaka, H.9
-
29
-
-
0038450313
-
Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death
-
Thumkeo D, Keel J, Ishizaki T, Hirose M, Nonomura K, Oshima H, Oshima M, Taketo MM, Narumiya S. 2003. Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death. Mol Cell Biol 23:5043-5055.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5043-5055
-
-
Thumkeo, D.1
Keel, J.2
Ishizaki, T.3
Hirose, M.4
Nonomura, K.5
Oshima, H.6
Oshima, M.7
Taketo, M.M.8
Narumiya, S.9
-
30
-
-
23844442551
-
ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo
-
Thumkeo D, Shimizu Y, Sakamoto S, Yamada S, Narumiya S. 2005. ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo. Genes Cells 10:825-834.
-
(2005)
Genes Cells
, vol.10
, pp. 825-834
-
-
Thumkeo, D.1
Shimizu, Y.2
Sakamoto, S.3
Yamada, S.4
Narumiya, S.5
-
31
-
-
18444414614
-
ROCK and mDial antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts
-
Tsuji T, Ishizaki T, Okamoto M, Higashida C, Kimura K, Furuyashiki T, Arakawa Y, Birge RB, Nakamoto T, Hirai H, Narumiya S. 2002. ROCK and mDial antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J Cell Biol 157:819-830.
-
(2002)
J Cell Biol
, vol.157
, pp. 819-830
-
-
Tsuji, T.1
Ishizaki, T.2
Okamoto, M.3
Higashida, C.4
Kimura, K.5
Furuyashiki, T.6
Arakawa, Y.7
Birge, R.B.8
Nakamoto, T.9
Hirai, H.10
Narumiya, S.11
-
32
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, Tamakawa H, Yamagami K, Inui J, Maekawa M, et al. 1997. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389:990-994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
Tamakawa, H.7
Yamagami, K.8
Inui, J.9
Maekawa, M.10
-
33
-
-
0030894714
-
The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization
-
Vincent S, Settleman J. 1997. The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization. Mol Cell Biol 17:2247-2256.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2247-2256
-
-
Vincent, S.1
Settleman, J.2
-
34
-
-
0037092045
-
The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway
-
Ward Y, Yap SF, Ravichandran V, Matsumura F, Ito M, Spinelli B, Kelly K. 2002. The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway. J Cell Biol 157:291-302.
-
(2002)
J Cell Biol
, vol.157
, pp. 291-302
-
-
Ward, Y.1
Yap, S.F.2
Ravichandran, V.3
Matsumura, F.4
Ito, M.5
Spinelli, B.6
Kelly, K.7
-
35
-
-
22344435165
-
Spatial regulation of CLASP affinity for microtubules by Racl and GSK3β in migrating epithelial cells
-
Wittmann T, Waterman-Storer CM. 2005. Spatial regulation of CLASP affinity for microtubules by Racl and GSK3β in migrating epithelial cells. J Cell Biol 169:929-939.
-
(2005)
J Cell Biol
, vol.169
, pp. 929-939
-
-
Wittmann, T.1
Waterman-Storer, C.M.2
-
36
-
-
0038037737
-
RhoA and ROCK promote migration by limiting membrane protrusions
-
Worthylake RA, Burridge K. 2003. RhoA and ROCK promote migration by limiting membrane protrusions. J Biol Chem 278:13578-13584.
-
(2003)
J Biol Chem
, vol.278
, pp. 13578-13584
-
-
Worthylake, R.A.1
Burridge, K.2
-
37
-
-
0035374569
-
RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway
-
Yamaguchi Y, Katoh H, Yasui H, Mori K, Negishi M. 2001. RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway. J Biol Chem 276:18977-18983.
-
(2001)
J Biol Chem
, vol.276
, pp. 18977-18983
-
-
Yamaguchi, Y.1
Katoh, H.2
Yasui, H.3
Mori, K.4
Negishi, M.5
-
38
-
-
23744480002
-
The Rho kinases I and II regulate different aspects of myosin II activity
-
Yoneda A, Multhaupt HA, Couchman JR. 2005. The Rho kinases I and II regulate different aspects of myosin II activity. J Cell Biol 170:443-453.
-
(2005)
J Cell Biol
, vol.170
, pp. 443-453
-
-
Yoneda, A.1
Multhaupt, H.A.2
Couchman, J.R.3
|