Activation of hypoxia-inducible factor-1 in pulmonary arterial smooth muscle cells by endothelin-1

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 8, 2013, Pages

  Pisarcik, Sarah ^a   Maylor, Julie ^a   Lu, Wenju ^a   Yun, Xin ^a   Undem, Clark ^a   Sylvester, J T ^a   Semenza, Gregg L ^a   Shimoda, Larissa A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium; Prolyl hydroxylase; Pulmonary hypertension

Indexed keywords

ENDOTHELIN 1; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; REACTIVE OXYGEN METABOLITE; CALCIUM; CYCLO(TRP ASP PRO VAL LEU); CYCLO(TRP-ASP-PRO-VAL-LEU); CYCLOPEPTIDE; ENDOTHELIN A RECEPTOR; HIF1A PROTEIN, RAT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHD2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; ENZYMATIC DEGRADATION; ENZYME ACTIVATION; ENZYME INDUCTION; IMMUNOBLOTTING; LUNG ALVEOLUS CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERIAL SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; RAT; ANIMAL; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION; GENETICS; MALE; METABOLISM; PHYSIOLOGY; PULMONARY ARTERY; SMOOTH MUSCLE FIBER; WISTAR RAT;

ANIMALS; BASE SEQUENCE; CALCIUM; CELL HYPOXIA; CELLS, CULTURED; ENDOTHELIN-1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MYOCYTES, SMOOTH MUSCLE; PEPTIDES, CYCLIC; PROCOLLAGEN-PROLINE DIOXYGENASE; PULMONARY ARTERY; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTOR, ENDOTHELIN A; RNA, MESSENGER;

MLCS; MLOWN;

EID: 84878634927     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00081.2012     Document Type: Article

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