Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK 1/2 map kinase

Canadian Journal of Physiology and Pharmacology

Volumn 88, Issue 8, 2010, Pages 830-839

  Meoli, David F ^a   White, R James ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Endothelin; MAP kinase; Migration; Vascular smooth muscle cell

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR AGONIST; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N ACETYL 3,3 DIPHENYL DEXTRO ALANYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN; PLATELET DERIVED GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; AORTA; ARTICLE; BLOOD VESSEL; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; EX VIVO STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG; LUNG CIRCULATION; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; RECEPTOR DENSITY; SMOOTH MUSCLE FIBER; VASODILATATION; WESTERN BLOTTING;

ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; CELL LINE; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIN-1; HUMANS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE INHIBITORS; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; SIGNAL TRANSDUCTION; TUNICA MEDIA;

EID: 78650193081     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/Y10-059     Document Type: Article

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