-
2
-
-
0018992813
-
ATPdependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation
-
Ciechanover, A., Heller, H., Elias, S., Haas, A. L., and Hershko, A. ATPdependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation. Proc. Natl. Acad. Sci. USA 1980, 77, 1365-68.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1365-1368
-
-
Ciechanover, A.1
Heller, H.2
Elias, S.3
Haas, A.L.4
Hershko, A.5
-
3
-
-
0019000271
-
Proposed role of ATP in protein breakdown: conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis
-
Hershko, A., Ciechanover, A., Heller, H., Haas, A. L., and Rose, I. A. Proposed role of ATP in protein breakdown: conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc. Natl. Acad. Sci. USA 1980, 77, 1783-86.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1783-1786
-
-
Hershko, A.1
Ciechanover, A.2
Heller, H.3
Haas, A.L.4
Rose, I.A.5
-
4
-
-
0020478717
-
Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation
-
Haas, A. L., Warms, J. V. B., Hershko, A., and Rose, I. A. Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation. J. Biol. Chem. 1982, 257, 2543-48.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 2543-2548
-
-
Haas, A.L.1
Warms, J.V.B.2
Hershko, A.3
Rose, I.A.4
-
5
-
-
0033485280
-
The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases
-
Cane, D. E. and Walsh, C. T. The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases. Chem. Biol. 1999, 6, R319-R25.
-
(1999)
Chem. Biol.
, vol.6
-
-
Cane, D.E.1
Walsh, C.T.2
-
6
-
-
0021099710
-
Components of ubiquitin-protein ligase system
-
Hershko, A., Heller, H., Elias, S., and Ciechanover, A. Components of ubiquitin-protein ligase system. J. Biol. Chem. 1983, 258, 8206-14.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 8206-8214
-
-
Hershko, A.1
Heller, H.2
Elias, S.3
Ciechanover, A.4
-
7
-
-
0021996450
-
Functional heterogeneity of ubiquitin carrier proteins
-
Pickart, C. M. and Rose, I. A. Functional heterogeneity of ubiquitin carrier proteins. J. Biol. Chem. 1985, 260, 1573-81.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 1573-1581
-
-
Pickart, C.M.1
Rose, I.A.2
-
8
-
-
0023236126
-
The yeast DNA repair gene RAD6 encodes a ubiquitinconjugating enzyme
-
Jentsch, S., McGrath, J. P., and Varshavsky, A. The yeast DNA repair gene RAD6 encodes a ubiquitinconjugating enzyme. Nature 1987, 329, 131-34.
-
(1987)
Nature
, vol.329
, pp. 131-134
-
-
Jentsch, S.1
McGrath, J.P.2
Varshavsky, A.3
-
9
-
-
0023722309
-
The yeast cell cycle gene CDC34 encodes a ubiquitinconjugating enzyme
-
Goebl, M. G., Yochem, J., Jentsch, S., McGrath, J. P., Varshavsky, A., and Byers, B. The yeast cell cycle gene CDC34 encodes a ubiquitinconjugating enzyme. Science 1988, 241, 1331-35.
-
(1988)
Science
, vol.241
, pp. 1331-1335
-
-
Goebl, M.G.1
Yochem, J.2
Jentsch, S.3
McGrath, J.P.4
Varshavsky, A.5
Byers, B.6
-
10
-
-
0021925909
-
RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartates
-
Reynolds, P., Weber, S., and Prakash, L. RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartates. Proc. Natl. Acad. Sci. USA 1985, 82, 168-72.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 168-172
-
-
Reynolds, P.1
Weber, S.2
Prakash, L.3
-
11
-
-
0025952497
-
Stable ester conjugate between the Saccharomyces cerevisiae RAD6 protein and ubiquitin has no biological activity
-
Sung, P., Prakash, S., and Prakash, L. Stable ester conjugate between the Saccharomyces cerevisiae RAD6 protein and ubiquitin has no biological activity. J. Mol. Biol. 1991, 221, 745-49.
-
(1991)
J. Mol. Biol.
, vol.221
, pp. 745-749
-
-
Sung, P.1
Prakash, S.2
Prakash, L.3
-
12
-
-
0028859433
-
Characterization of a dominant negative mutant of the cell cycle ubiquitin-conjugating enzyme Cdc34
-
Banerjee, A., Deshaies, R. J., and Chau, V. Characterization of a dominant negative mutant of the cell cycle ubiquitin-conjugating enzyme Cdc34. J. Biol. Chem. 1995, 270, 26209-15.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26209-26215
-
-
Banerjee, A.1
Deshaies, R.J.2
Chau, V.3
-
13
-
-
0037673562
-
The comparative proteomics of ubiquitination in mouse
-
Semple, C. A. The comparative proteomics of ubiquitination in mouse. Genome Res 2003, 13, 1389-94.
-
(2003)
Genome Res
, vol.13
, pp. 1389-1394
-
-
Semple, C.A.1
-
14
-
-
0042934147
-
Drug discovery in the ubiquitin regulatory pathway
-
Wong, B. R., Parlati, F., Quk, K., Demo, S., Pray, T., Huang, J., Payan, D. G., and Bennett, M. K. Drug discovery in the ubiquitin regulatory pathway. Drug Discov. Today 2003, 8, 746-54.
-
(2003)
Drug Discov. Today
, vol.8
, pp. 746-754
-
-
Wong, B.R.1
Parlati, F.2
Quk, K.3
Demo, S.4
Pray, T.5
Huang, J.6
Payan, D.G.7
Bennett, M.K.8
-
15
-
-
0026776440
-
Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzyme
-
Kolman, C. J., Toth, J., and Gonda, D. K. Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzyme. EMBO J. 1992, 11, 3081-90.
-
(1992)
EMBO J.
, vol.11
, pp. 3081-3090
-
-
Kolman, C.J.1
Toth, J.2
Gonda, D.K.3
-
16
-
-
0026772161
-
A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function, and evolution of the E2s
-
Silver, E. T., Gwozd, T. J., Ptak, C., Goebl, M. G., and Ellison, M. J. A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function, and evolution of the E2s. EMBO J. 1992, 11, 3091-98.
-
(1992)
EMBO J.
, vol.11
, pp. 3091-3098
-
-
Silver, E.T.1
Gwozd, T.J.2
Ptak, C.3
Goebl, M.G.4
Ellison, M.J.5
-
17
-
-
0027970881
-
Functional and physical characterization of the cell cycle ubiquitin-conjugating enzyme CDC34 (UBC3)
-
Ptak, C., Prendergast, J. A., Hodgins, R., Kay, C. M., Chau, V., and Ellison, M. J. Functional and physical characterization of the cell cycle ubiquitin-conjugating enzyme CDC34 (UBC3). J. Biol. Chem. 1994, 269, 26539-45.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26539-26545
-
-
Ptak, C.1
Prendergast, J.A.2
Hodgins, R.3
Kay, C.M.4
Chau, V.5
Ellison, M.J.6
-
18
-
-
0029821534
-
The tail of a ubiquitin-conjugating enzyme redirects multi-ubiquitin chain synthesis from the lysine 48-linked configuration to a novel nonlysine-linked form
-
Hodgins, R., Gwozd, C., Arnason, T., Cummings, M., and Ellison, M. J. The tail of a ubiquitin-conjugating enzyme redirects multi-ubiquitin chain synthesis from the lysine 48-linked configuration to a novel nonlysine-linked form. J. Biol. Chem. 1996, 271, 28766-71.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28766-28771
-
-
Hodgins, R.1
Gwozd, C.2
Arnason, T.3
Cummings, M.4
Ellison, M.J.5
-
19
-
-
0032512737
-
An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiae
-
Mathias, N., Steussy, C. N., and Goebl, M. G. An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiae. J. Biol. Chem. 1998, 273, 4040-45.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4040-4045
-
-
Mathias, N.1
Steussy, C.N.2
Goebl, M.G.3
-
20
-
-
0026653834
-
Threedimensional structure of a ubiquitinconjugating enzyme (E2)
-
Cook, W. J., Jeffrey, L. C., Sullivan, M. L., and Vierstra, R. D. Threedimensional structure of a ubiquitinconjugating enzyme (E2). J. Biol. Chem. 1992, 267, 15116-21.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15116-15121
-
-
Cook, W.J.1
Jeffrey, L.C.2
Sullivan, M.L.3
Vierstra, R.D.4
-
21
-
-
0027788114
-
Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4
-
Cook, W. J., Jeffrey, L. C., Xu, Y., and Chau, V. Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4. Biochemistry 1993, 32, 13809-17.
-
(1993)
Biochemistry
, vol.32
, pp. 13809-13817
-
-
Cook, W.J.1
Jeffrey, L.C.2
Xu, Y.3
Chau, V.4
-
22
-
-
0030457014
-
Ubiquitindependent protein degradation
-
Hochstrasser, M. Ubiquitindependent protein degradation. Annu. Rev. Genet. 1996, 30, 405-39.
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
23
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart, C. M. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 2001, 70, 503-33.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
24
-
-
0025164762
-
Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins
-
Seufert, W. and Jentsch, S. Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins. EMBO J. 1990, 9, 543-50.
-
(1990)
EMBO J.
, vol.9
, pp. 543-550
-
-
Seufert, W.1
Jentsch, S.2
-
25
-
-
0027511214
-
Resistance to cadmium mediated by ubiquitin-dependent proteolysis
-
Jungmann, J., Reins, H.-A., Schobert, C., and Jentsch, S. Resistance to cadmium mediated by ubiquitin-dependent proteolysis. Nature 1993, 361, 369-71.
-
(1993)
Nature
, vol.361
, pp. 369-371
-
-
Jungmann, J.1
Reins, H.-A.2
Schobert, C.3
Jentsch, S.4
-
26
-
-
0025980627
-
Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival
-
Heinemeyer, W., Kleinschmidt, J. A., Saidowsky, J., Escher, C., and Wolf, D. H. Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival. EMBO J. 1991, 10, 555-62.
-
(1991)
EMBO J.
, vol.10
, pp. 555-562
-
-
Heinemeyer, W.1
Kleinschmidt, J.A.2
Saidowsky, J.3
Escher, C.4
Wolf, D.H.5
-
27
-
-
0029119522
-
A proteolytic pathway that recognizes ubiquitin as a degradation signal
-
Johnson, E. S., Ma, P. C., Ota, I. M., and Varshavsky, A. A proteolytic pathway that recognizes ubiquitin as a degradation signal. J. Biol. Chem. 1995, 270, 17442-56.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17442-17456
-
-
Johnson, E.S.1
Ma, P.C.2
Ota, I.M.3
Varshavsky, A.4
-
28
-
-
0025632969
-
UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation
-
Seufert, W., McGrath, J. P., and Jentsch, S. UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation. EMBO J. 1990, 9, 4535-41.
-
(1990)
EMBO J.
, vol.9
, pp. 4535-4541
-
-
Seufert, W.1
McGrath, J.P.2
Jentsch, S.3
-
29
-
-
0033591363
-
Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkBa
-
Gonen, H., Bercovich, B., Orian, A., Carrano, A., Takizawa, C., Yamanaka, K., Pagano, M., Iwai, K., and Ciechanover, A. Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkBa. J. Biol. Chem. 1999, 274, 14823-30.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14823-14830
-
-
Gonen, H.1
Bercovich, B.2
Orian, A.3
Carrano, A.4
Takizawa, C.5
Yamanaka, K.6
Pagano, M.7
Iwai, K.8
Ciechanover, A.9
-
30
-
-
0033279836
-
SCF and cullin/RING H2-based ubiquitin ligases
-
Deshaies, R. J. SCF and cullin/RING H2-based ubiquitin ligases. Annu. Rev. Cell Devel. Biol. 1999, 15, 435-67.
-
(1999)
Annu. Rev. Cell Devel. Biol.
, vol.15
, pp. 435-467
-
-
Deshaies, R.J.1
-
31
-
-
0028114987
-
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae
-
Schwob, E., Bohm, T., Mendenhall, M. D., and Nasmyth, K. The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 1994, 79, 233-44.
-
(1994)
Cell
, vol.79
, pp. 233-244
-
-
Schwob, E.1
Bohm, T.2
Mendenhall, M.D.3
Nasmyth, K.4
-
32
-
-
0030695025
-
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
-
Feldman, R. M. R., Correll, C. C., Kaplan, K. B., and Deshaies, R. J. A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 1997, 91, 221-30.
-
(1997)
Cell
, vol.91
, pp. 221-230
-
-
Feldman, R.M.R.1
Correll, C.C.2
Kaplan, K.B.3
Deshaies, R.J.4
-
33
-
-
0030662523
-
Fbox proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
-
Skowyra, D., Craig, K. L., Tyers, M., Elledge, S. J., and Harper, J. W. Fbox proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 1997, 91, 209-19.
-
(1997)
Cell
, vol.91
, pp. 209-219
-
-
Skowyra, D.1
Craig, K.L.2
Tyers, M.3
Elledge, S.J.4
Harper, J.W.5
-
34
-
-
0032031607
-
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/Fbox protein complexes that regulate cell division and methionine biosynthesis in yeast
-
Patton, E. E., Willems, A. R., Sa, D., Kuras, L., Thomas, D., Craig, K. L., and Tyers, M. Cdc53 is a scaffold protein for multiple Cdc34/Skp1/Fbox protein complexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev. 1998, 12, 692-705.
-
(1998)
Genes Dev.
, vol.12
, pp. 692-705
-
-
Patton, E.E.1
Willems, A.R.2
Sa, D.3
Kuras, L.4
Thomas, D.5
Craig, K.L.6
Tyers, M.7
-
35
-
-
0034308251
-
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
-
Jackson, P. K., Eldridge, A. G., Freed, E., Furstenthal, L., Hsu, J. Y., Kaiser, B. K., and Reimann, J. D. R. The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Trends Cell Biol. 2000, 10, 429-39.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 429-439
-
-
Jackson, P.K.1
Eldridge, A.G.2
Freed, E.3
Furstenthal, L.4
Hsu, J.Y.5
Kaiser, B.K.6
Reimann, J.D.R.7
-
36
-
-
1042268088
-
Functional interactions of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro
-
Kus, B., Caldon, C. E., Andorn-Broza, R., and Edwards, A. M. Functional interactions of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins: Structure, Function, and Bioinformatics 2004, 54, 455-67.
-
(2004)
Proteins: Structure, Function, and Bioinformatics
, vol.54
, pp. 455-467
-
-
Kus, B.1
Caldon, C.E.2
Andorn-Broza, R.3
Edwards, A.M.4
-
37
-
-
0030666729
-
Role of Cue1p in ubiq-uitination and degradation at the ER surface
-
Biederer, T., Volkwein, C., and Sommer, T. Role of Cue1p in ubiq-uitination and degradation at the ER surface. Science 1997, 278, 1806-09.
-
(1997)
Science
, vol.278
, pp. 1806-1809
-
-
Biederer, T.1
Volkwein, C.2
Sommer, T.3
-
38
-
-
0037566901
-
For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection
-
Kostova, Z. and Wolf, D. H. For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection. EMBO J. 2003, 22, 2309-17.
-
(2003)
EMBO J.
, vol.22
, pp. 2309-2317
-
-
Kostova, Z.1
Wolf, D.H.2
-
39
-
-
0035144199
-
Hrd1p/Der3p is a membraneanchored ubiquitin ligase required for ER-associated degradation
-
Bays, N. W., Gardner, R. G., Seelig, L. P., Joazeiro, C. A., and Hampton, R. Y. Hrd1p/Der3p is a membraneanchored ubiquitin ligase required for ER-associated degradation. Nature Cell Biol. 2000, 3, 24-29.
-
(2000)
Nature Cell Biol.
, vol.3
, pp. 24-29
-
-
Bays, N.W.1
Gardner, R.G.2
Seelig, L.P.3
Joazeiro, C.A.4
Hampton, R.Y.5
-
40
-
-
0033780610
-
A regulatory link between ER-associated protein degradation and the unfoldedprotein response
-
Friedlander, R., Jarosch, E., Urban, J., Volkwein, C., and Sommer, T. A regulatory link between ER-associated protein degradation and the unfoldedprotein response. Nature Cell Biol. 2000, 2, 379-84.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 379-384
-
-
Friedlander, R.1
Jarosch, E.2
Urban, J.3
Volkwein, C.4
Sommer, T.5
-
41
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
Travers, K. J., Patil, C. K., Wodicka, L., Lockhart, D. J., Weissman, J. S., and Walter, P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 2000, 101, 249-58.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
Patil, C.K.2
Wodicka, L.3
Lockhart, D.J.4
Weissman, J.S.5
Walter, P.6
-
42
-
-
0035887277
-
A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Mata2 repressor degradation
-
Swanson, R., Locher, M., and Hochstrasser, M. A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Mata2 repressor degradation. Genes Dev. 2001, 15, 2660-74.
-
(2001)
Genes Dev.
, vol.15
, pp. 2660-2674
-
-
Swanson, R.1
Locher, M.2
Hochstrasser, M.3
-
43
-
-
0035844139
-
Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits
-
Tiwari, S. and Weissman, A. M. Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. J. Biol. Chem. 2001, 276, 16193-200.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16193-16200
-
-
Tiwari, S.1
Weissman, A.M.2
-
44
-
-
0141532211
-
Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2{thorn}
-
Webster, J. M., Tiwari, S., Weissman, A. M., and Wojcikiewicz, R. J. H. Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2{thorn}. J. Biol. Chem. 2003, 278, 38238-46.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38238-38246
-
-
Webster, J.M.1
Tiwari, S.2
Weissman, A.M.3
Wojcikiewicz, R.J.H.4
-
45
-
-
0035807839
-
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum
-
Fang, S., Ferrone, M., Yang, C., Jensen, J. P., Tiwari, S., and Weissman, A. M. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 2001, 98, 14422-27.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14422-14427
-
-
Fang, S.1
Ferrone, M.2
Yang, C.3
Jensen, J.P.4
Tiwari, S.5
Weissman, A.M.6
-
46
-
-
0027327659
-
A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum
-
Sommer, T. and Jentsch, S. A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum. Nature 1993, 365, 176-79.
-
(1993)
Nature
, vol.365
, pp. 176-179
-
-
Sommer, T.1
Jentsch, S.2
-
47
-
-
0029985369
-
Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway
-
Biederer, T., Volkwein, C., and Sommer, T. Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J. 1996, 15, 2069-76.
-
(1996)
EMBO J.
, vol.15
, pp. 2069-2076
-
-
Biederer, T.1
Volkwein, C.2
Sommer, T.3
-
48
-
-
0029838640
-
ER degradation of a misfolded luminal protein by the cytosolic ubiuqitinproteasome pathway
-
Hiller, M. M., Finger, A., Schweiger, M., and Wolf, D. H. ER degradation of a misfolded luminal protein by the cytosolic ubiuqitinproteasome pathway. Science 1996, 273, 1725-28.
-
(1996)
Science
, vol.273
, pp. 1725-1728
-
-
Hiller, M.M.1
Finger, A.2
Schweiger, M.3
Wolf, D.H.4
-
49
-
-
0027198563
-
Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATa2 repressor
-
Chen, P., Johnson, P., Sommer, T., Jentsch, S., and Hochstrasser, M. Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATa2 repressor. Cell 1993, 74, 357-69.
-
(1993)
Cell
, vol.74
, pp. 357-369
-
-
Chen, P.1
Johnson, P.2
Sommer, T.3
Jentsch, S.4
Hochstrasser, M.5
-
50
-
-
0035875921
-
Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p
-
Walter, J., Urban, J., Volkwein, C., and Sommer, T. Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. EMBO J. 2001, 20, 3124-31.
-
(2001)
EMBO J.
, vol.20
, pp. 3124-3131
-
-
Walter, J.1
Urban, J.2
Volkwein, C.3
Sommer, T.4
-
51
-
-
0035912183
-
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
-
Rao, H., Uhlmann, F., Nasmyth, K., and Varshavsky, A. Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 2001, 410, 955-59.
-
(2001)
Nature
, vol.410
, pp. 955-959
-
-
Rao, H.1
Uhlmann, F.2
Nasmyth, K.3
Varshavsky, A.4
-
52
-
-
0032472322
-
The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor
-
Byrd, C., Turner, G. C., and Varshavsky, A. The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. EMBO J. 1998, 17, 269-77.
-
(1998)
EMBO J.
, vol.17
, pp. 269-277
-
-
Byrd, C.1
Turner, G.C.2
Varshavsky, A.3
-
53
-
-
0034730134
-
Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome pathway
-
Kaplun, L., Ivantsiv, Y., Kornitzer, D., and Raveh, D. Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome pathway. Proc. Natl. Acad. Sci. USA 2000, 97, 10077-82.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10077-10082
-
-
Kaplun, L.1
Ivantsiv, Y.2
Kornitzer, D.3
Raveh, D.4
-
54
-
-
0030021770
-
Expression of the ubiquitinconjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification
-
Koken, M. H. M., Hoogerbrugge, J. W., Jaspers-Dekker, I., de Wit, J., Willemsen, R., Roest, H. P., Grootegoed, J. A., and Hoeijmakers, J. H. J. Expression of the ubiquitinconjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification. Dev. Biol. 1996, 173, 119-32.
-
(1996)
Dev. Biol.
, vol.173
, pp. 119-132
-
-
Koken, M.H.M.1
Hoogerbrugge, J.W.2
Jaspers-Dekker, I.3
De Wit, J.4
Willemsen, R.5
Roest, H.P.6
Grootegoed, J.A.7
Hoeijmakers, J.H.J.8
-
55
-
-
16044372544
-
Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification
-
Roest, H. P., van Klaveren, J., de Wit, J., van Gurp, C. G., Koken, M. H. M., Vermey, M., van Roijen, J. H., Hoogerbrugge, J. W., Vreeberg, M. T. M., Baarends, W. M., Bootsma, D., Grootegoed, J. A., and Hoeijmakers, J. H. J. Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. Cell 1996, 86, 799-810.
-
(1996)
Cell
, vol.86
, pp. 799-810
-
-
Roest, H.P.1
Van Klaveren, J.2
De Wit, J.3
Van Gurp, C.G.4
Koken, M.H.M.5
Vermey, M.6
Van Roijen, J.H.7
Hoogerbrugge, J.W.8
Vreeberg, M.T.M.9
Baarends, W.M.10
Bootsma, D.11
Grootegoed, J.A.12
Hoeijmakers, J.H.J.13
-
56
-
-
0037025163
-
An essential role of N-terminal arginylation in cardovascular development
-
Kwon, Y. T., Kashina, A. S., Davydov, I. V., Hu, R.-G., An, J. Y., Seo, J. W., Du, F., and Varshavsky, A. An essential role of N-terminal arginylation in cardovascular development. Science 2002, 297, 96-99.
-
(2002)
Science
, vol.297
, pp. 96-99
-
-
Kwon, Y.T.1
Kashina, A.S.2
Davydov, I.V.3
Hu, R.-G.4
An, J.Y.5
Seo, J.W.6
Du, F.7
Varshavsky, A.8
-
57
-
-
0343570543
-
Ubc8p functions in catabolite degradation of fructose-1,6-bisphosphatase in yeast
-
Schule, T., Rose, M., Entian, K.-D., Thumm, M., and Wolf, D. H. Ubc8p functions in catabolite degradation of fructose-1,6-bisphosphatase in yeast. EMBO J. 2000, 19, 2161-67.
-
(2000)
EMBO J.
, vol.19
, pp. 2161-2167
-
-
Schule, T.1
Rose, M.2
Entian, K.-D.3
Thumm, M.4
Wolf, D.H.5
-
58
-
-
0037711091
-
TNF-a increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220K
-
Li, Y.-P., Lecker, S. H., Chen, Y., Waddell, I. D., Goldberg, A. L., and Reid, M. B. TNF-a increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220K. FASEB J. 2003, 17, 1048-57.
-
(2003)
FASEB J.
, vol.17
, pp. 1048-1057
-
-
Li, Y.-P.1
Lecker, S.H.2
Chen, Y.3
Waddell, I.D.4
Goldberg, A.L.5
Reid, M.B.6
-
59
-
-
0029065710
-
Inducation of ubiquitinconjugating enzymes during terminal erythroid differentiation
-
Wefes, I., Mastrandrea, L. D., Haldeman, M., Koury, S. T., Tamburlin, J., Pickart, C. M., and Finley, D. Inducation of ubiquitinconjugating enzymes during terminal erythroid differentiation. Proc. Natl. Acad. Sci. USA 1995, 92, 4982-86.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4982-4986
-
-
Wefes, I.1
Mastrandrea, L.D.2
Haldeman, M.3
Koury, S.T.4
Tamburlin, J.5
Pickart, C.M.6
Finley, D.7
-
60
-
-
0141994845
-
A cytosolic domain of the yeast Zrt1 zinc transporter is required for its post-translational inactivation in response to zinc and cadmium
-
Gitan, R. S., Shababi, M., Kramer, M., and Eide, D. J. A cytosolic domain of the yeast Zrt1 zinc transporter is required for its post-translational inactivation in response to zinc and cadmium. J. Biol. Chem. 2003, 278, 39558-64.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39558-39564
-
-
Gitan, R.S.1
Shababi, M.2
Kramer, M.3
Eide, D.J.4
-
61
-
-
0030054178
-
Ubiquitination of a yeast plasma membrane receptor signals its ligandstimulated endocytosis
-
Hicke, L. and Riezman, H. Ubiquitination of a yeast plasma membrane receptor signals its ligandstimulated endocytosis. Cell 1996, 84, 277-87.
-
(1996)
Cell
, vol.84
, pp. 277-287
-
-
Hicke, L.1
Riezman, H.2
-
62
-
-
0035149694
-
Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis
-
Dunn, R. and Hicke, L. Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis. Mol. Biol. Cell 2001, 12, 421-35.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 421-435
-
-
Dunn, R.1
Hicke, L.2
-
63
-
-
0141442586
-
Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins
-
Hicke, L. and Dunn, R. Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu. Rev. Cell Devel. Biol. 2003, 19, 141-72.
-
(2003)
Annu. Rev. Cell Devel. Biol.
, vol.19
, pp. 141-172
-
-
Hicke, L.1
Dunn, R.2
-
64
-
-
0036463909
-
Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatin
-
Ulrich, H. D. Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatin. Eukaryotic Cell 2002, 1, 1-10.
-
(2002)
Eukaryotic Cell
, vol.1
, pp. 1-10
-
-
Ulrich, H.D.1
-
65
-
-
0037068455
-
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
-
Hoege, C., Pfander, B., Moldovan, G.-L., Pyrowolakis, G., and Jentsch, S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 2002, 419, 135-41.
-
(2002)
Nature
, vol.419
, pp. 135-141
-
-
Hoege, C.1
Pfander, B.2
Moldovan, G.-L.3
Pyrowolakis, G.4
Jentsch, S.5
-
66
-
-
0141831006
-
Control of spontaneous and damageinduced mutagenesis by SUMO and ubiquitin conjugation
-
Stelter, P. and Ulrich, H. D. Control of spontaneous and damageinduced mutagenesis by SUMO and ubiquitin conjugation. Nature 2003, 425, 188-91.
-
(2003)
Nature
, vol.425
, pp. 188-191
-
-
Stelter, P.1
Ulrich, H.D.2
-
67
-
-
0037248593
-
A conserved RING finger protein required for histone H2B monoubiquitination and cell size control
-
Hwang, W. W., Venkatasubrahmanyam, S., Ianculescu, A. G., Tong, A., Boone, C., and Madhani, H. D. A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Mol. Cell 2003, 11, 261-66.
-
(2003)
Mol. Cell
, vol.11
, pp. 261-266
-
-
Hwang, W.W.1
Venkatasubrahmanyam, S.2
Ianculescu, A.G.3
Tong, A.4
Boone, C.5
Madhani, H.D.6
-
68
-
-
0034695456
-
Rad6-dependent ubiquitination of histone H2B in yeast
-
Robzyk, K., Recht, J., and Osley, M. A. Rad6-dependent ubiquitination of histone H2B in yeast. Science 2000, 287, 501-04.
-
(2000)
Science
, vol.287
, pp. 501-504
-
-
Robzyk, K.1
Recht, J.2
Osley, M.A.3
-
69
-
-
0037248944
-
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter
-
Wood, A., Krogan, N. J., Dover, J., Schneider, J., Heidt, J., Boateng, M. A., Dean, K., Golshani, A., Zhang, Y., Greenblatt, J. F., Johnston, M., and Shilatifard, A. Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol. Cell 2003, 11, 267-74.
-
(2003)
Mol. Cell
, vol.11
, pp. 267-274
-
-
Wood, A.1
Krogan, N.J.2
Dover, J.3
Schneider, J.4
Heidt, J.5
Boateng, M.A.6
Dean, K.7
Golshani, A.8
Zhang, Y.9
Greenblatt, J.F.10
Johnston, M.11
Shilatifard, A.12
-
70
-
-
0038434056
-
A superfamily of protein tags: ubiquitin, SUMO and related modifiers
-
Schwartz, D. C. and Hochstrasser, M. A superfamily of protein tags: ubiquitin, SUMO and related modifiers. Trends Biochem. Sci. 2003, 28, 321-28.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 321-328
-
-
Schwartz, D.C.1
Hochstrasser, M.2
-
71
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun, Z.-W. and Allis, C. D. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 2002, 418, 104-08.
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.-W.1
Allis, C.D.2
-
72
-
-
0033525582
-
Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
-
Hofmann, R. M. and Pickart, C. M. Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 1999, 96, 645-53.
-
(1999)
Cell
, vol.96
, pp. 645-653
-
-
Hofmann, R.M.1
Pickart, C.M.2
-
73
-
-
0034600851
-
Two RING finger proteins mediate cooperation between ubiquitinconjugating enzymes in DNA repair
-
Ulrich, H. D. and Jentsch, S. Two RING finger proteins mediate cooperation between ubiquitinconjugating enzymes in DNA repair. EMBO J. 2000, 19, 3388-97.
-
(2000)
EMBO J.
, vol.19
, pp. 3388-3397
-
-
Ulrich, H.D.1
Jentsch, S.2
-
74
-
-
2342477917
-
The novel functions of ubiquitination in signaling
-
Sun, L. and Chen, Z. J. The novel functions of ubiquitination in signaling. Curr. Opin. Cell Biol. 2004, 16, 119-26.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 119-126
-
-
Sun, L.1
Chen, Z.J.2
-
75
-
-
0026782393
-
The Pas2 protein essential for peroxisome biogenesis is related to ubiquitinconjugating enzymes
-
Wiebel, F. F. and Kunau, W. H. The Pas2 protein essential for peroxisome biogenesis is related to ubiquitinconjugating enzymes. Nature 1992, 359, 73-76.
-
(1992)
Nature
, vol.359
, pp. 73-76
-
-
Wiebel, F.F.1
Kunau, W.H.2
-
76
-
-
0032127487
-
The ubiquitin-conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery
-
van der Klei, I. J., Hilbrands, R. E., Kiel, J. A. K. W., Rasmussen, S. W., Cregg, J. M., and Veenhuis, M. The ubiquitin-conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery. EMBO J. 1998, 17, 3608-18.
-
(1998)
EMBO J.
, vol.17
, pp. 3608-3618
-
-
Van Der Klei, I.J.1
Hilbrands, R.E.2
Kiel, J.A.K.W.3
Rasmussen, S.W.4
Cregg, J.M.5
Veenhuis, M.6
-
77
-
-
0033549487
-
Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane
-
Koller, A., Snyder, W. B., Faber, K. N., Wenzel, T. J., Rangell, L., Keller, G. A., and Subramani, S. Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane. J. Cell Biol. 1999, 146, 99-112.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 99-112
-
-
Koller, A.1
Snyder, W.B.2
Faber, K.N.3
Wenzel, T.J.4
Rangell, L.5
Keller, G.A.6
Subramani, S.7
-
78
-
-
0041827355
-
Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome
-
Eckert, J. H. and Johnsson, N. Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome. J. Cell Sci. 2003, 116, 3623-34.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3623-3634
-
-
Eckert, J.H.1
Johnsson, N.2
-
79
-
-
0029863734
-
E2-C a cyclinselective ubiquitin carrier protein required for the destruction of mitotic cyclins
-
Aristarkhov, A., Eytan, E., Moghe, A., Admon, A., Hershko, A., and Ruderman, J. V. E2-C a cyclinselective ubiquitin carrier protein required for the destruction of mitotic cyclins. Proc. Natl. Acad. Sci. USA 1996, 93, 4294-99.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4294-4299
-
-
Aristarkhov, A.1
Eytan, E.2
Moghe, A.3
Admon, A.4
Hershko, A.5
Ruderman, J.V.6
-
80
-
-
0036284778
-
The anaphase-promoting complex: proteolysis in mitosis and beyond
-
Peters, J. M. The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol. Cell 2002, 9, 931-43.
-
(2002)
Mol. Cell
, vol.9
, pp. 931-943
-
-
Peters, J.M.1
-
81
-
-
0030113930
-
Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation
-
Yu, H., King, R. W., Peters, J.-M., and Kirschner, M. W. Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation. Curr. Biol. 1996, 6, 455-66.
-
(1996)
Curr. Biol.
, vol.6
, pp. 455-466
-
-
Yu, H.1
King, R.W.2
Peters, J.-M.3
Kirschner, M.W.4
-
82
-
-
0037965786
-
Two ubiquitinconjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin
-
Seino, H., Kishi, T., Nishitani, H., and Yamao, F. Two ubiquitinconjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin. Mol. Cell. Biol. 2003, 23, 3497-505.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3497-3505
-
-
Seino, H.1
Kishi, T.2
Nishitani, H.3
Yamao, F.4
-
83
-
-
0030909599
-
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
-
Townsley, F. M., Aristarkhov, A., Beck, S., Hershko, A., and Ruderman, J. V. Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase. Proc. Natl. Acad. Sci. USA 1997, 94, 2362-67.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2362-2367
-
-
Townsley, F.M.1
Aristarkhov, A.2
Beck, S.3
Hershko, A.4
Ruderman, J.V.5
-
84
-
-
0032526671
-
Functional analysis of the Saccharomyces cerevisiae UBC11 gene
-
Townsley, F. M. and Ruderman, J. V. Functional analysis of the Saccharomyces cerevisiae UBC11 gene. Yeast 1998, 14, 747-57.
-
(1998)
Yeast
, vol.14
, pp. 747-757
-
-
Townsley, F.M.1
Ruderman, J.V.2
-
85
-
-
0036900880
-
Mechanisms of enveloped RNA virus budding
-
Pornillos, O., Garrus, J. E., and Sundquist, W. I. Mechanisms of enveloped RNA virus budding. Trends Cell Biol. 2002, 12, 569-79.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 569-579
-
-
Pornillos, O.1
Garrus, J.E.2
Sundquist, W.I.3
-
86
-
-
0036790444
-
Lessons from viral manipulation of protein disposal pathways
-
Furman, M. H. and Ploegh, H. L. Lessons from viral manipulation of protein disposal pathways. J. Clin. Invest. 2002, 110, 875-79.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 875-879
-
-
Furman, M.H.1
Ploegh, H.L.2
-
87
-
-
0026594934
-
A ubiquitin conjugating enzyme encoded by African swine fever virus
-
Hingamp, P. M., Arnold, J. E., Mayer, R. J., and Dixon, L. K. A ubiquitin conjugating enzyme encoded by African swine fever virus. EMBO. J. 1992, 11, 361-66.
-
(1992)
EMBO. J.
, vol.11
, pp. 361-366
-
-
Hingamp, P.M.1
Arnold, J.E.2
Mayer, R.J.3
Dixon, L.K.4
-
88
-
-
0026542277
-
Genes homologous to ubiquitin-conjugating proteins and eukaryotic transcription factor SII in African swine fever virus
-
Rodriguez, J. M., Salas, M. L., and Vinuela, E. Genes homologous to ubiquitin-conjugating proteins and eukaryotic transcription factor SII in African swine fever virus. Virology 1992, 186, 40-52.
-
(1992)
Virology
, vol.186
, pp. 40-52
-
-
Rodriguez, J.M.1
Salas, M.L.2
Vinuela, E.3
-
89
-
-
0037062483
-
Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0
-
Hagglund, R. and Roizman, B. Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0. Proc. Natl. Acad. Sci. USA 2002, 99, 7889-94.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7889-7894
-
-
Hagglund, R.1
Roizman, B.2
-
90
-
-
0141638441
-
Essential role of E2-25K/Hip-2 in mediating amyloid-b toxicity
-
Song, S., Kim, S.-Y., Hong, Y.-M., Jo, D.-G., Lee, J.-Y., Shim, S. M., Chung, C.-W., Seo, S. J., Yoo, Y. J., Koh, J.-Y., Lee, M. C., Yates, A. J., Ichijo, H., and Jung, Y.-K. Essential role of E2-25K/Hip-2 in mediating amyloid-b toxicity. Mol. Cell 2003, 12, 553-63.
-
(2003)
Mol. Cell
, vol.12
, pp. 553-563
-
-
Song, S.1
Kim, S.-Y.2
Hong, Y.-M.3
Jo, D.-G.4
Lee, J.-Y.5
Shim, S.M.6
Chung, C.-W.7
Seo, S.J.8
Yoo, Y.J.9
Koh, J.-Y.10
Lee, M.C.11
Yates, A.J.12
Ichijo, H.13
Jung, Y.-K.14
-
91
-
-
0034730172
-
Inhibition of the ubiquitin-proteasome system in Alzheimer's disease
-
Lam, Y. A., Pickart, C. M., Alban, A., Landon, M., Jamieson, C., ramage, R., Mayer, R. J., and Layfield, R. Inhibition of the ubiquitin-proteasome system in Alzheimer's disease. Proc. Natl. Acad. Sci. USA 2000, 97, 9902-06.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9902-9906
-
-
Lam, Y.A.1
Pickart, C.M.2
Alban, A.3
Landon, M.4
Jamieson, C.5
Ramage, R.6
Mayer, R.J.7
Layfield, R.8
-
92
-
-
0042674162
-
UbcH10 is the cancer-related E2 ubiquitinconjugating enzyme
-
Okamoto, Y., Ozaki, T., Miyazaki, K., Aoyama, M., Miyazaki, M., and Nakagawara, A. UbcH10 is the cancer-related E2 ubiquitinconjugating enzyme. Cancer Res. 2003, 63, 4167-73.
-
(2003)
Cancer Res.
, vol.63
, pp. 4167-4173
-
-
Okamoto, Y.1
Ozaki, T.2
Miyazaki, K.3
Aoyama, M.4
Miyazaki, M.5
Nakagawara, A.6
-
93
-
-
0036532135
-
Rad6 over-expression induces multinucleation, centrosom amplification, abnormal mitosis, aneuploidy, and transformation
-
Shekhar, M. P. V., Lyakhovich, A., Visscher, D. W., Heng, H., and Kondrat, N. Rad6 over-expression induces multinucleation, centrosom amplification, abnormal mitosis, aneuploidy, and transformation. Cancer Res. 2002, 62, 2115-24.
-
(2002)
Cancer Res.
, vol.62
, pp. 2115-2124
-
-
Shekhar, M.P.V.1
Lyakhovich, A.2
Visscher, D.W.3
Heng, H.4
Kondrat, N.5
-
94
-
-
0035286622
-
SUMO, ubiquitin's mysterious cousin.
-
Muller, S., Hoege, C., Pyrowolakis, G., and Jentsch, S. SUMO, ubiquitin's mysterious cousin. Nature Rev. Mol. Cell Biol. 2001, 2, 202-10.
-
(2001)
Nature Rev. Mol. Cell Biol.
, vol.2
, pp. 202-210
-
-
Muller, S.1
Hoege, C.2
Pyrowolakis, G.3
Jentsch, S.4
-
95
-
-
0034253588
-
Evolution and function of ubiquitin-like proteinconjugation systems
-
Hochstrasser, M. Evolution and function of ubiquitin-like proteinconjugation systems. Nature Cell Biol. 2000, 2, E153-E57.
-
(2000)
Nature Cell Biol.
, vol.2
-
-
Hochstrasser, M.1
-
96
-
-
0037456828
-
Insights into the ubiquitin transfer cascade from the structure of the E1 for NEDD8
-
Walden, H., Podgorski, M. S., and Schulman, B. A. Insights into the ubiquitin transfer cascade from the structure of the E1 for NEDD8. Nature 2003, 422, 330-34.
-
(2003)
Nature
, vol.422
, pp. 330-334
-
-
Walden, H.1
Podgorski, M.S.2
Schulman, B.A.3
-
97
-
-
0037033071
-
Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation
-
Bencsath, K. P., Podgorski, M. S., Pagala, V. R., Slaughter, C. A., and Schulman, B. A. Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation. J. Biol. Chem. 2002, 277, 47938-45.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47938-47945
-
-
Bencsath, K.P.1
Podgorski, M.S.2
Pagala, V.R.3
Slaughter, C.A.4
Schulman, B.A.5
-
98
-
-
0026325730
-
Cloning of a 16-kDa ubiquitin carrier protein from wheat and Arabidopsis thaliana. Identification of functional domains by in vitro mutagenesis
-
Sullivan, M. L. and Vierstra, R. D. Cloning of a 16-kDa ubiquitin carrier protein from wheat and Arabidopsis thaliana. Identification of functional domains by in vitro mutagenesis. J. Biol. Chem. 1991, 266, 23878-85.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 23878-23885
-
-
Sullivan, M.L.1
Vierstra, R.D.2
-
99
-
-
0023789174
-
Functional diversity among putative E2 isozymes in the mechanism of ubiquitin-histone ligation
-
Haas, A. L., Bright, P. M., and Jackson, V. E. Functional diversity among putative E2 isozymes in the mechanism of ubiquitin-histone ligation. J. Biol. Chem. 1988, 163, 13268-75.
-
(1988)
J. Biol. Chem.
, vol.163
, pp. 13268-13275
-
-
Haas, A.L.1
Bright, P.M.2
Jackson, V.E.3
-
100
-
-
0038526241
-
Protein interactions within the N-end rule ubiquitin ligation pathway
-
Siepmann, T. J., Bohnsack, R. N., Tokgoz, Z., Baboshina, O., and Haas, A. L. Protein interactions within the N-end rule ubiquitin ligation pathway. J. Biol. Chem. 2003, 278, 9448-57.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9448-9457
-
-
Siepmann, T.J.1
Bohnsack, R.N.2
Tokgoz, Z.3
Baboshina, O.4
Haas, A.L.5
-
101
-
-
0033516511
-
Characterization of the binding interface between ubiquitin and class I human ubiquitin-conjugating enzyme 2b by multidimensional heteronuclear NMR spectroscopy in solution
-
Miura, T., Klaus, W., Gsell, B., Miyamoto, C., and Senn, H. Characterization of the binding interface between ubiquitin and class I human ubiquitin-conjugating enzyme 2b by multidimensional heteronuclear NMR spectroscopy in solution. J. Mol. Biol. 1999, 290, 213-28.
-
(1999)
J. Mol. Biol.
, vol.290
, pp. 213-228
-
-
Miura, T.1
Klaus, W.2
Gsell, B.3
Miyamoto, C.4
Senn, H.5
-
102
-
-
0034788322
-
Structure of a conjugating enzymeubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail
-
Hamilton, K. S., Ellison, M. J., Barber, K. R., Williams, R. S., Huzil, J. T., Mckenna, S., Ptak, C., Glover, M., and Shaw, G. S. Structure of a conjugating enzymeubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail. Structure 2001, 9, 897-904.
-
(2001)
Structure
, vol.9
, pp. 897-904
-
-
Hamilton, K.S.1
Ellison, M.J.2
Barber, K.R.3
Williams, R.S.4
Huzil, J.T.5
Mckenna, S.6
Ptak, C.7
Glover, M.8
Shaw, G.S.9
-
103
-
-
0038579251
-
An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis
-
McKenna, S., Moraes, T., Pastushok, L., Ptak, C., Xiao, W., Spyracopoulos, L., and Ellison, M. J. An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis. J. Biol. Chem. 2003, 278, 13151-58.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13151-13158
-
-
McKenna, S.1
Moraes, T.2
Pastushok, L.3
Ptak, C.4
Xiao, W.5
Spyracopoulos, L.6
Ellison, M.J.7
-
104
-
-
0034602928
-
RING domains: master builders of molecular scaffolds?
-
Borden, K. L. RING domains: master builders of molecular scaffolds? J. Mol. Biol. 2000, 295, 1103-12.
-
(2000)
J. Mol. Biol.
, vol.295
, pp. 1103-1112
-
-
Borden, K.L.1
-
105
-
-
0032463343
-
RING fingers and Bboxes: zinc-binding protein-protein interaction domains
-
Borden, K. L. RING fingers and Bboxes: zinc-binding protein-protein interaction domains. Biochem. Cell Biol. 1998, 76, 351-58.
-
(1998)
Biochem. Cell Biol.
, vol.76
, pp. 351-358
-
-
Borden, K.L.1
-
106
-
-
0034682718
-
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases
-
Zheng, N., Wang, P., Jeffrey, P. D., and Pavletich, N. P. Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell 2000, 102, 533-39.
-
(2000)
Cell
, vol.102
, pp. 533-539
-
-
Zheng, N.1
Wang, P.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
107
-
-
0037610801
-
Binding and recognition in the assembly of an active BRCA1-BARD1 ubiquitin ligase complex
-
Brzovic, P. S., Keeffe, J. R., Nishikawa, H., Mayamoto, K., Fox, D., Fukuda, M., Ohta, T., and Klevit, R. Binding and recognition in the assembly of an active BRCA1-BARD1 ubiquitin ligase complex. Proc. Natl. Acad. Sci. USA 2003, 100, 5646-51.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5646-5651
-
-
Brzovic, P.S.1
Keeffe, J.R.2
Nishikawa, H.3
Mayamoto, K.4
Fox, D.5
Fukuda, M.6
Ohta, T.7
Klevit, R.8
-
108
-
-
0032741446
-
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade
-
Huang, L., Kinnucan, E., Wang, G., Beaudenon, S., Howley, P. M., Huibregtse, J. M., and Pavletich, N. P. Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science 1999, 286, 1321-26.
-
(1999)
Science
, vol.286
, pp. 1321-1326
-
-
Huang, L.1
Kinnucan, E.2
Wang, G.3
Beaudenon, S.4
Howley, P.M.5
Huibregtse, J.M.6
Pavletich, N.P.7
-
109
-
-
0037756787
-
Structure of a b-TrCP1-Skp1-b-catenin complex: destruction motif binding and lysine specificity of the SCFb-TrCP1 ubiquitin ligase
-
Wu, G., Xu, G., Schulman, B. A., Jeffrey, P. D., Harper, J. W., and Pavletich, N. P. Structure of a b-TrCP1-Skp1-b-catenin complex: destruction motif binding and lysine specificity of the SCFb-TrCP1 ubiquitin ligase. Mol. Cell 2003, 11, 1145-456.
-
(2003)
Mol. Cell
, vol.11
, pp. 1145-1456
-
-
Wu, G.1
Xu, G.2
Schulman, B.A.3
Jeffrey, P.D.4
Harper, J.W.5
Pavletich, N.P.6
-
110
-
-
0034804672
-
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
-
Brzovic, P. S., Rajagopal, P., Hoyt, D. W., King, M.-C., and Klevit, R. E. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nature Struct. Biol. 2001, 8, 833-37.
-
(2001)
Nature Struct. Biol.
, vol.8
, pp. 833-837
-
-
Brzovic, P.S.1
Rajagopal, P.2
Hoyt, D.W.3
King, M.-C.4
Klevit, R.E.5
-
111
-
-
0036383262
-
The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription
-
Conaway, R. C. and Conaway, J. W. The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription. Adv. Cancer Res. 2002, 85, 1-12.
-
(2002)
Adv. Cancer Res.
, vol.85
, pp. 1-12
-
-
Conaway, R.C.1
Conaway, J.W.2
-
112
-
-
18344391432
-
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
-
Zheng, N., Schulman, B. A., Song, L., Miller, J. J., Jeffrey, P. D., Wang, P., Chu, C., Koepp, D. M., Elledge, S. J., Pagano, M., Conaway, R. C., Conaway, J. W., Harper, J. W., and Pavletich, N. P. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 2002, 416, 703-09.
-
(2002)
Nature
, vol.416
, pp. 703-709
-
-
Zheng, N.1
Schulman, B.A.2
Song, L.3
Miller, J.J.4
Jeffrey, P.D.5
Wang, P.6
Chu, C.7
Koepp, D.M.8
Elledge, S.J.9
Pagano, M.10
Conaway, R.C.11
Conaway, J.W.12
Harper, J.W.13
Pavletich, N.P.14
-
113
-
-
17844411190
-
NEDD8 recruits E2-ubiquitin to SCF E3 ligase
-
Kawakami, T., Chiba, T., Suzuki, T., Iwai, K., Yamanaka, K., Minato, N., Suzuki, H., Shimbara, N., Hidaka, Y., Osaka, F., Omata, M., and Tanaka, K. NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J. 2001, 20, 4003-12.
-
(2001)
EMBO J.
, vol.20
, pp. 4003-4012
-
-
Kawakami, T.1
Chiba, T.2
Suzuki, T.3
Iwai, K.4
Yamanaka, K.5
Minato, N.6
Suzuki, H.7
Shimbara, N.8
Hidaka, Y.9
Osaka, F.10
Omata, M.11
Tanaka, K.12
-
114
-
-
0037016754
-
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34
-
Wu, K., Chen, A., Tan, P., and Pan, Z.-Q. The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34. J. Biol. Chem. 2002, 277, 516-27.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 516-527
-
-
Wu, K.1
Chen, A.2
Tan, P.3
Pan, Z.-Q.4
-
115
-
-
0037462424
-
Structural basis for phosphodependent substrate selection and orientation by the SDFCdc4 ubiquitin ligase
-
Orlicky, S., Tang, X., Willems, A., Tyers, M., and Sicheri, F. Structural basis for phosphodependent substrate selection and orientation by the SDFCdc4 ubiquitin ligase. Cell 2003, 112, 243-56.
-
(2003)
Cell
, vol.112
, pp. 243-256
-
-
Orlicky, S.1
Tang, X.2
Willems, A.3
Tyers, M.4
Sicheri, F.5
-
116
-
-
0141522457
-
Release of ubiquitincharged Cdc34-S@Ub from the RING domain is essential for ubiquitination of the SCFCdc4-bound substrate Sic1
-
Deffenbaugh, A. E., Scaglione, K. M., Buranda, T., Sklar, L. A., and Skowyra, D. Release of ubiquitincharged Cdc34-S@Ub from the RING domain is essential for ubiquitination of the SCFCdc4-bound substrate Sic1. Cell 2003, 114, 611-22.
-
(2003)
Cell
, vol.114
, pp. 611-622
-
-
Deffenbaugh, A.E.1
Scaglione, K.M.2
Buranda, T.3
Sklar, L.A.4
Skowyra, D.5
-
117
-
-
0037756792
-
Context of multiubiquitin chain attachment influences the rate of Sic1 degradation
-
Petroski, M. D. and Deshaies, R. J. Context of multiubiquitin chain attachment influences the rate of Sic1 degradation. Mol. Cell 2003, 11, 1435-44.
-
(2003)
Mol. Cell
, vol.11
, pp. 1435-1444
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
118
-
-
0041706156
-
A proteomics approach to understanding protein ubiquitination
-
Peng, J., Schwartz, D., Elias, J. E., Thoreen, C. C., Cheng, D., Marsischky, G., Roelofs, J., Finley, D., and Gygi, S. P. A proteomics approach to understanding protein ubiquitination. Nature Biotechnol. 2003, 21, 921-26.
-
(2003)
Nature Biotechnol.
, vol.21
, pp. 921-926
-
-
Peng, J.1
Schwartz, D.2
Elias, J.E.3
Thoreen, C.C.4
Cheng, D.5
Marsischky, G.6
Roelofs, J.7
Finley, D.8
Gygi, S.P.9
-
119
-
-
0035375052
-
Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes
-
Pringa, E., Martinez-Noel, G., Muller, U., and Harbers, K. Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes. J. Biol. Chem. 2001, 276, 19617-23.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19617-19623
-
-
Pringa, E.1
Martinez-Noel, G.2
Muller, U.3
Harbers, K.4
-
120
-
-
0033525589
-
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly
-
Koegl, M., Hoppe, T., Schlenker, S., Ulrich, H. D., Mayer, T. U., and Jentsch, S. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell 1999, 96, 635-44.
-
(1999)
Cell
, vol.96
, pp. 635-644
-
-
Koegl, M.1
Hoppe, T.2
Schlenker, S.3
Ulrich, H.D.4
Mayer, T.U.5
Jentsch, S.6
-
121
-
-
0035900793
-
CHIP is a U-boxdependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation
-
Jiang, J., Ballinger, C. A., Wu, Y., Dai, Q., Cyr, D. M., Hohfeld, J., and Patterson, C. CHIP is a U-boxdependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation. J. Biol. Chem. 2001, 276, 42938-44.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42938-42944
-
-
Jiang, J.1
Ballinger, C.A.2
Wu, Y.3
Dai, Q.4
Cyr, D.M.5
Hohfeld, J.6
Patterson, C.7
-
122
-
-
0035684430
-
CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein
-
Murata, S., Minami, Y., Minami, M., Chiba, T., and Tanaka, K. CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein. EMBO Rep. 2001, 2, 1133-8.
-
(2001)
EMBO Rep.
, vol.2
, pp. 1133-1138
-
-
Murata, S.1
Minami, Y.2
Minami, M.3
Chiba, T.4
Tanaka, K.5
-
123
-
-
0037389970
-
Structural insights into the U-box, a domain associated with multi-ubiquitination
-
Ohi, M. D., Vander Kooi, C. W., Rosenberg, J. A., Chazin, W. J., and Gould, K. L. Structural insights into the U-box, a domain associated with multi-ubiquitination. Nature Struct. Biol. 2003, 10, 250-55.
-
(2003)
Nature Struct. Biol.
, vol.10
, pp. 250-255
-
-
Ohi, M.D.1
Van Kooi, C.W.2
Rosenberg, J.A.3
Chazin, W.J.4
Gould, K.L.5
-
124
-
-
0034708216
-
The U box is a modified RING finger-a common domain in ubiquitination
-
Aravind, L. and Koonin, E. V. The U box is a modified RING finger-a common domain in ubiquitination. Curr. Biol. 2000, 10, R132-R24.
-
(2000)
Curr. Biol.
, vol.10
-
-
Aravind, L.1
Koonin, E.V.2
-
125
-
-
0035980094
-
U box proteins as a new family of ubiquitin-protein ligases
-
Hatakeyama, S., Yada, M., Matsumoto, M., Ishida, N., and Nakayama, K. I. U box proteins as a new family of ubiquitin-protein ligases. J. Biol. Chem. 2001, 276, 33111-20.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33111-33120
-
-
Hatakeyama, S.1
Yada, M.2
Matsumoto, M.3
Ishida, N.4
Nakayama, K.I.5
-
126
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse, J. M., Scheffner, M., Beaudenon, S., and Howley, P. M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 1995, 92, 2563-67.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2563-2567
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
127
-
-
0025932933
-
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
-
Huibregtse, J. M., Scheffner, M., and Howley, P. M. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J. 1991, 10, 4129-35.
-
(1991)
EMBO J.
, vol.10
, pp. 4129-4135
-
-
Huibregtse, J.M.1
Scheffner, M.2
Howley, P.M.3
-
128
-
-
0028898424
-
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
-
Scheffner, M., Nuber, U., and Huibregtse, J. M. Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 1995, 373, 81-83.
-
(1995)
Nature
, vol.373
, pp. 81-83
-
-
Scheffner, M.1
Nuber, U.2
Huibregtse, J.M.3
-
129
-
-
0037249354
-
Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase
-
Verdecia, M. A., Joazeiro, C. A. P., Wells, N. J., Ferrer, J.-L., Bowman, M. E., Hunter, T., and Noel, J. P. Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase. Mol. Cell 2003, 11, 249-59.
-
(2003)
Mol. Cell
, vol.11
, pp. 249-259
-
-
Verdecia, M.A.1
Joazeiro, C.A.P.2
Wells, N.J.3
Ferrer, J.-L.4
Bowman, M.E.5
Hunter, T.6
Noel, J.P.7
-
130
-
-
0036177128
-
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitinconjugating enzyme Ubc9 and RanGAP1
-
Bernier-Villamor, V., Sampson, D. A., Matunis, M. J., and Lima, C. D. Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitinconjugating enzyme Ubc9 and RanGAP1. Cell 2002, 108, 345-56.
-
(2002)
Cell
, vol.108
, pp. 345-356
-
-
Bernier-Villamor, V.1
Sampson, D.A.2
Matunis, M.J.3
Lima, C.D.4
-
131
-
-
0035875079
-
Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer
-
VanDemark, A. P., Hofmann, R. M., Tsui, C., Pickart, C. M., and Wolberger, C. Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell 2001, 105, 711-20.
-
(2001)
Cell
, vol.105
, pp. 711-720
-
-
VanDemark, A.P.1
Hofmann, R.M.2
Tsui, C.3
Pickart, C.M.4
Wolberger, C.5
-
132
-
-
0034644474
-
Activation of the IkB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., and Chen, Z. J. Activation of the IkB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 2000, 103, 351-61.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
Slaughter, C.7
Pickart, C.8
Chen, Z.J.9
-
133
-
-
0024280501
-
Dissecting the catalytic triad of a serine protease
-
Carter, P. and Wells, J. A. Dissecting the catalytic triad of a serine protease. Nature 1988, 332, 564-68.
-
(1988)
Nature
, vol.332
, pp. 564-568
-
-
Carter, P.1
Wells, J.A.2
-
134
-
-
0028673327
-
Families of cysteine peptidases
-
Rawlings, N. D. and Barrett, A. J. Families of cysteine peptidases. Meth. Enzymol. 1994, 244, 461-86.
-
(1994)
Meth. Enzymol.
, vol.244
, pp. 461-486
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
135
-
-
0030772385
-
Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system
-
Tong, H., Hateboer, G., Perrakis, A., Bernards, R., and Sixma, T. K. Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system. J. Biol. Chem. 1997, 272, 21381-87.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21381-21387
-
-
Tong, H.1
Hateboer, G.2
Perrakis, A.3
Bernards, R.4
Sixma, T.K.5
-
136
-
-
0141753130
-
A conserved catalytic residue in the E2 enzyme family
-
Wu, P.-Y., Hanlon, M., Eddins, M., Tsui, C., Rogers, R., Jensen, J. P., Matunis, M. J., Weissman, A. M., Wolberger, C., and Pickart, C. M. A conserved catalytic residue in the E2 enzyme family. EMBO J. 2003, 22, 5241-50.
-
(2003)
EMBO J.
, vol.22
, pp. 5241-5250
-
-
Wu, P.-Y.1
Hanlon, M.2
Eddins, M.3
Tsui, C.4
Rogers, R.5
Jensen, J.P.6
Matunis, M.J.7
Weissman, A.M.8
Wolberger, C.9
Pickart, C.M.10
-
137
-
-
0037184947
-
Crystal structure of a UBPfamily deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
-
Hu, M., Li, P., Li, M., Li, W., Yao, T., Wu, J.-W., Gu, W., Cohen, R. E., and Shi, Y. Crystal structure of a UBPfamily deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell 2002, 111, 1041-54.
-
(2002)
Cell
, vol.111
, pp. 1041-1054
-
-
Hu, M.1
Li, P.2
Li, M.3
Li, W.4
Yao, T.5
Wu, J.-W.6
Gu, W.7
Cohen, R.E.8
Shi, Y.9
-
138
-
-
0033638223
-
Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast
-
Mossessova, E. and Lima, C. D. Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast. Mol. Cell 2000, 5, 865-76.
-
(2000)
Mol. Cell
, vol.5
, pp. 865-876
-
-
Mossessova, E.1
Lima, C.D.2
-
139
-
-
0033565867
-
Structural basis for the specificity of ubiquitin C-terminal hydrolases
-
Johnston, S. C., Riddle, S. M., Cohen, R. E., and Hill, C. P. Structural basis for the specificity of ubiquitin C-terminal hydrolases. EMBO J. 1999, 18, 3877-87.
-
(1999)
EMBO J.
, vol.18
, pp. 3877-3887
-
-
Johnston, S.C.1
Riddle, S.M.2
Cohen, R.E.3
Hill, C.P.4
-
140
-
-
0030065766
-
Mechanism of ubiquitin conjugating enzyme E2-230K: catalysis involving a thiol relay?
-
Berleth, E. S. and Pickart, C. M. Mechanism of ubiquitin conjugating enzyme E2-230K: catalysis involving a thiol relay? Biochemistry 1995, 35, 1664-71.
-
(1995)
Biochemistry
, vol.35
, pp. 1664-1671
-
-
Berleth, E.S.1
Pickart, C.M.2
-
141
-
-
0032526948
-
A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors
-
Hauser, H.-P., Bardroff, M., Pyrowolakis, G., and Jentsch, S. A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. J. Cell Biol. 1998, 141, 1415-22.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1415-1422
-
-
Hauser, H.-P.1
Bardroff, M.2
Pyrowolakis, G.3
Jentsch, S.4
-
142
-
-
0031962188
-
Role of UEV-1, an inactive variant of the E2 ubiquitinconjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells
-
Sancho, E., Vila, M. R., Sanchez-Pulido, L., Lozano, J. J., Paciucci, R., Nadal, M., Fox, M., Harvey, C., Bercovich, B., Loukili, N., Ciechanover, A., Lin, S. L., Sanz, F., Estivill, X., Valencia, A., and Thomson, T. M. Role of UEV-1, an inactive variant of the E2 ubiquitinconjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells. Mol. Cell Biol. 1998, 18, 576-89.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 576-589
-
-
Sancho, E.1
Vila, M.R.2
Sanchez-Pulido, L.3
Lozano, J.J.4
Paciucci, R.5
Nadal, M.6
Fox, M.7
Harvey, C.8
Bercovich, B.9
Loukili, N.10
Ciechanover, A.11
Lin, S.L.12
Sanz, F.13
Estivill, X.14
Valencia, A.15
Thomson, T.M.16
-
143
-
-
0035913278
-
TAK1 is a ubiquitindependent kinase of MKK and IKK
-
Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J.-I., and Chen, Z. J. TAK1 is a ubiquitindependent kinase of MKK and IKK. Nature 2001, 412, 346-51.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.-I.5
Chen, Z.J.6
-
144
-
-
0034881624
-
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
-
Moraes, T. F., Edwards, R. A., McKenna, S., Pastushok, L., Xiao, W., Glover, J. N., and Ellison, M. J. Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13. Nature Struct. Biol. 2001, 8, 669-73.
-
(2001)
Nature Struct. Biol.
, vol.8
, pp. 669-673
-
-
Moraes, T.F.1
Edwards, R.A.2
McKenna, S.3
Pastushok, L.4
Xiao, W.5
Glover, J.N.6
Ellison, M.J.7
-
145
-
-
0037470244
-
Protein-protein interactions in an E2-RING finger complex: implications for ubiquitindependent DNA damage repair
-
Ulrich, H. D. Protein-protein interactions in an E2-RING finger complex: implications for ubiquitindependent DNA damage repair. J. Biol. Chem. 2003, 278, 7051-58.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7051-7058
-
-
Ulrich, H.D.1
-
146
-
-
0036902646
-
Receptor downregulation and multivesticular-body sorting
-
Katzmann, D. J., Odorizzi, G., and Emr, S. D. Receptor downregulation and multivesticular-body sorting. Nature Rev. Mol. Cell Biol. 2002, 3, 893-905.
-
(2002)
Nature Rev. Mol. Cell Biol.
, vol.3
, pp. 893-905
-
-
Katzmann, D.J.1
Odorizzi, G.2
Emr, S.D.3
-
147
-
-
0035958546
-
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
-
Katzmann, D. J., Babst, M., and Emr, S. D. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 2001, 106, 145-55.
-
(2001)
Cell
, vol.106
, pp. 145-155
-
-
Katzmann, D.J.1
Babst, M.2
Emr, S.D.3
-
148
-
-
17944363138
-
Tsg101 and the vaculolar protein sorting pathway are essential for HIV-1 budding
-
Garrus, J. E., von Schwedler, U. K., Pornillos, O. W., Morham, S. G., Zavitz, K. H., Wang, H. E., Wettstein, D. A., Stray, K. M., Cote, M., Rich, R. L., Myszka, D. G., and Sundquist, W. I. Tsg101 and the vaculolar protein sorting pathway are essential for HIV-1 budding. Cell 2001, 107, 55-65.
-
(2001)
Cell
, vol.107
, pp. 55-65
-
-
Garrus, J.E.1
Von Schwedler, U.K.2
Pornillos, O.W.3
Morham, S.G.4
Zavitz, K.H.5
Wang, H.E.6
Wettstein, D.A.7
Stray, K.M.8
Cote, M.9
Rich, R.L.10
Myszka, D.G.11
Sundquist, W.I.12
-
149
-
-
0035658023
-
HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress
-
Martin-Serrano, J., Zang, T., and Bieniasz, P. D. HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nature Med. 2001, 7, 1313-19.
-
(2001)
Nature Med.
, vol.7
, pp. 1313-1319
-
-
Martin-Serrano, J.1
Zang, T.2
Bieniasz, P.D.3
-
150
-
-
0036568729
-
Tsg101: HIV-1's ticket to ride
-
Carter, C. A. Tsg101: HIV-1's ticket to ride. Trends Microbiol. 2002, 10, 203-05.
-
(2002)
Trends Microbiol.
, vol.10
, pp. 203-205
-
-
Carter, C.A.1
-
151
-
-
0036829172
-
Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
-
Pornillos, W., alam, S. L., Davis, D. R., and Sundquist, W. I. Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein. Nature Struct. Biol. 2002, 9, 812-17.
-
(2002)
Nature Struct. Biol.
, vol.9
, pp. 812-817
-
-
Pornillos, W.1
Alam, S.L.2
Davis, D.R.3
Sundquist, W.I.4
-
152
-
-
0037093316
-
Structure and functional interactions of the Tsg101 UEV domain
-
Pornillos, O., Alam, S. L., Rich, R. L., Myszka, D. G., Davis, D. R., and Sundquist, W. I. Structure and functional interactions of the Tsg101 UEV domain. EMBO J. 2002, 21, 2397-406.
-
(2002)
EMBO J.
, vol.21
, pp. 2397-2406
-
-
Pornillos, O.1
Alam, S.L.2
Rich, R.L.3
Myszka, D.G.4
Davis, D.R.5
Sundquist, W.I.6
-
153
-
-
0041888375
-
Tsg101 control of human immunodeficiency virus type 1 Gag trafficking and release
-
Goff, A., Ehrlich, L. S., Cohen, S. N., and Carter, C. A. Tsg101 control of human immunodeficiency virus type 1 Gag trafficking and release. J. Virol. 2003, 77, 9173-82.
-
(2003)
J. Virol.
, vol.77
, pp. 9173-9182
-
-
Goff, A.1
Ehrlich, L.S.2
Cohen, S.N.3
Carter, C.A.4
-
154
-
-
0031201741
-
TSG101 may be the prototype of a class of dominant negative ubiquitin regulators
-
Koonin, E. V. and Abagyan, R. A. TSG101 may be the prototype of a class of dominant negative ubiquitin regulators. Nature Genet. 1997, 16, 330-31.
-
(1997)
Nature Genet.
, vol.16
, pp. 330-331
-
-
Koonin, E.V.1
Abagyan, R.A.2
-
155
-
-
85047669941
-
The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway
-
Hofmann, K. and Bucher, P. The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway. Trends Biochem. Sci. 1996, 21, 172-73.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 172-173
-
-
Hofmann, K.1
Bucher, P.2
-
156
-
-
0025913944
-
The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme
-
Dohmen, R. J., Madura, K., Bartel, B., and Varshavsky, A. The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme. Proc. Natl. Acad. Sci. USA 1991, 88, 7351-55.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7351-7355
-
-
Dohmen, R.J.1
Madura, K.2
Bartel, B.3
Varshavsky, A.4
-
157
-
-
0028314007
-
Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites
-
Bailly, V., Lamb, J., Sung, P., Prakash, S., and Prakash, L. Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites. Genes Dev. 1994, 8, 811-20.
-
(1994)
Genes Dev.
, vol.8
, pp. 811-820
-
-
Bailly, V.1
Lamb, J.2
Sung, P.3
Prakash, S.4
Prakash, L.5
-
158
-
-
0030632048
-
The N-end rule pathway of protein degradation
-
Varshavsky, A. The N-end rule pathway of protein degradation. Genes Cells 1997, 2, 13-28.
-
(1997)
Genes Cells
, vol.2
, pp. 13-28
-
-
Varshavsky, A.1
-
159
-
-
0037084028
-
Role of the ubiquitin-selective CDC48UFD1=NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates
-
Braun, S., Matuschewski, K., Rape, M., Thoms, S., and Jentsch, S. Role of the ubiquitin-selective CDC48UFD1=NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J. 2002, 21, 615-21.
-
(2002)
EMBO J.
, vol.21
, pp. 615-621
-
-
Braun, S.1
Matuschewski, K.2
Rape, M.3
Thoms, S.4
Jentsch, S.5
-
160
-
-
0025874685
-
Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family
-
Qin, S., Nakajima, B., Nomura, M., and Arfin, S. M. Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family. J. Biol. Chem. 1991, 266, 15549-54.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15549-15554
-
-
Qin, S.1
Nakajima, B.2
Nomura, M.3
Arfin, S.M.4
-
161
-
-
0028967267
-
Role of a ubiquitinconjugating enzyme in degradation of S-and M-phase cyclins
-
Seufert, W., Futcher, B., and Jentsch, S. Role of a ubiquitinconjugating enzyme in degradation of S-and M-phase cyclins. Nature 1995, 373, 78-81.
-
(1995)
Nature
, vol.373
, pp. 78-81
-
-
Seufert, W.1
Futcher, B.2
Jentsch, S.3
-
162
-
-
0035929279
-
An E3-like factor that promotes SUMO conjugation to the yeast septins
-
Johnson, E. S. and Gupta, A. A. An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 2001, 106, 735-44.
-
(2001)
Cell
, vol.106
, pp. 735-744
-
-
Johnson, E.S.1
Gupta, A.A.2
-
163
-
-
0030826334
-
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p
-
Johnson, E. S. and Blobel, G. Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p. J. Biol. Chem. 1997, 272, 26799-802.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26799-26802
-
-
Johnson, E.S.1
Blobel, G.2
-
164
-
-
0032522382
-
A novel protein modification pathway related to the ubiquitin system
-
Liakopoulos, D., Doenges, G., Matuschewski, K., and Jentsch, S. A novel protein modification pathway related to the ubiquitin system. EMBO J. 1998, 17, 2208-14.
-
(1998)
EMBO J.
, vol.17
, pp. 2208-2214
-
-
Liakopoulos, D.1
Doenges, G.2
Matuschewski, K.3
Jentsch, S.4
-
165
-
-
0032053829
-
Modification of yeast Cdc53p by the ubiquitin-related protein Rub1p affects function of the SCFCdc4 complex
-
Lammer, D., Mathias, N., Laplaza, J. M., Jiang, W., Liu, Y., Callis, J., Goebl, M., and Estelle, M. Modification of yeast Cdc53p by the ubiquitin-related protein Rub1p affects function of the SCFCdc4 complex. Genes Dev. 1998, 12, 914-26.
-
(1998)
Genes Dev.
, vol.12
, pp. 914-926
-
-
Lammer, D.1
Mathias, N.2
Laplaza, J.M.3
Jiang, W.4
Liu, Y.5
Callis, J.6
Goebl, M.7
Estelle, M.8
|