Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail

Structure

Volumn 9, Issue 10, 2001, Pages 897-904

  Hamilton, Katherine S ^a   Ellison, Michael J ^a   Barber, Kathryn R ^b   Williams, R Scott ^a   Huzil, John T ^a   McKenna, Sean ^a   Ptak, Christopher ^a   Glover, Mark ^a   Shaw, Gary S ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Covalent complex; NMR spectroscopy; Protein degradation; Protein protein interactions; Ubiquitination; X ray crystallography

Indexed keywords

THIOESTER; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME STRUCTURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; STRUCTURE ANALYSIS;

COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; LIGASES; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN FOOTPRINTING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SULFHYDRYL COMPOUNDS; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES;

SACCHAROMYCES CEREVISIAE;

EID: 0034788322     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00657-8     Document Type: Article

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