-
1
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart C.M. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70:2001;503-533.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
2
-
-
0034256031
-
Ubiquitin and its kin: How close are the family ties?
-
Jentsch S., Pyrowolakis G. Ubiquitin and its kin: how close are the family ties? Trends Cell Biol. 10:2000;335-342.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 335-342
-
-
Jentsch, S.1
Pyrowolakis, G.2
-
3
-
-
0034253588
-
Evolution and function of ubiquitin-like protein-conjugation systems
-
Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat. Cell Biol. 2:2000;E153-E157.
-
(2000)
Nat. Cell Biol.
, vol.2
-
-
Hochstrasser, M.1
-
4
-
-
0034730745
-
Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila
-
Pham A.D., Sauer F. Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila. Science. 289:2000;2357-2360.
-
(2000)
Science
, vol.289
, pp. 2357-2360
-
-
Pham, A.D.1
Sauer, F.2
-
5
-
-
0037131567
-
The UCH-L1 gene encodes two opposing enzymatic activities that affect α-synuclein degradation and Parkinson's disease susceptibility
-
Liu Y., et al. The UCH-L1 gene encodes two opposing enzymatic activities that affect α-synuclein degradation and Parkinson's disease susceptibility. Cell. 111:2002;209-218.
-
(2002)
Cell
, vol.111
, pp. 209-218
-
-
Liu, Y.1
-
6
-
-
0035877693
-
The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification
-
Sampson D.A., et al. The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification. J. Biol. Chem. 276:2001;21664-21669.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21664-21669
-
-
Sampson, D.A.1
-
7
-
-
0036177128
-
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
-
Bernier-Villamor V., et al. Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell. 108:2002;345-356.
-
(2002)
Cell
, vol.108
, pp. 345-356
-
-
Bernier-Villamor, V.1
-
8
-
-
0037389970
-
Structural insights into the U-box, a domain associated with multi-ubiquitination
-
Ohi M.D., et al. Structural insights into the U-box, a domain associated with multi-ubiquitination. Nat. Struct. Biol. 10:2003;250-255.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 250-255
-
-
Ohi, M.D.1
-
9
-
-
0035887277
-
A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matα2 repressor degradation
-
Swanson R., et al. A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matα2 repressor degradation. Genes Dev. 15:2001;2660-2674.
-
(2001)
Genes Dev.
, vol.15
, pp. 2660-2674
-
-
Swanson, R.1
-
10
-
-
0037059619
-
The nucleoporin RanBP2 has SUMO1 E3 ligase activity
-
Pichler A., et al. The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell. 108:2002;109-120.
-
(2002)
Cell
, vol.108
, pp. 109-120
-
-
Pichler, A.1
-
12
-
-
0036682364
-
Gene silencing: Trans-histone regulatory pathway in chromatin
-
Briggs S.D., et al. Gene silencing: trans-histone regulatory pathway in chromatin. Nature. 418:2002;498.
-
(2002)
Nature
, vol.418
, pp. 498
-
-
Briggs, S.D.1
-
13
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun Z.W., Allis C.D. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature. 418:2002;104-108.
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
14
-
-
0038795645
-
Signals for sorting of transmembrane proteins to endosomes and lysosomes
-
Bonifacino J.S., Traub L.M. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu. Rev. Biochem. 72:2003;395-447.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 395-447
-
-
Bonifacino, J.S.1
Traub, L.M.2
-
15
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C., et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 412:2001;346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
-
16
-
-
0037068455
-
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
-
Hoege C., et al. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature. 419:2002;135-141.
-
(2002)
Nature
, vol.419
, pp. 135-141
-
-
Hoege, C.1
-
17
-
-
0034791090
-
Ubiquitin enters the new millennium
-
Pickart C.M. Ubiquitin enters the new millennium. Mol. Cell. 8:2001;499-504.
-
(2001)
Mol. Cell
, vol.8
, pp. 499-504
-
-
Pickart, C.M.1
-
19
-
-
0023644679
-
Structure of ubiquitin refined at 1.8 Å resolution
-
Vijay-Kumar S., et al. Structure of ubiquitin refined at 1.8 Å resolution. J. Mol. Biol. 194:1987;531-544.
-
(1987)
J. Mol. Biol.
, vol.194
, pp. 531-544
-
-
Vijay-Kumar, S.1
-
20
-
-
0030028574
-
Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26S proteasome subunit 5
-
Baboshina O.V., Haas A.L. Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26S proteasome subunit 5. J. Biol. Chem. 271:1996;2823-2831.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2823-2831
-
-
Baboshina, O.V.1
Haas, A.L.2
-
21
-
-
0035286622
-
SUMO, ubiquitin's mysterious cousin
-
Muller S., et al. SUMO, ubiquitin's mysterious cousin. Nat. Rev. Mol. Cell Biol. 2:2001;202-210.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 202-210
-
-
Muller, S.1
-
22
-
-
0037005133
-
Autophagy in yeast: A review of the molecular machinery
-
Huang W., Klionsky D.J. Autophagy in yeast: a review of the molecular machinery. Cell Struct. Funct. 27:2002;409-420.
-
(2002)
Cell Struct. Funct.
, vol.27
, pp. 409-420
-
-
Huang, W.1
Klionsky, D.J.2
-
23
-
-
0037147318
-
A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast
-
Stade K., et al. A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. J. Biol. Chem. 277:2002;49554-49561.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49554-49561
-
-
Stade, K.1
-
24
-
-
0035969102
-
SUMO: Of branched proteins and nuclear bodies
-
Seeler J.S., Dejean A. SUMO: of branched proteins and nuclear bodies. Oncogene. 20:2001;7243-7249.
-
(2001)
Oncogene
, vol.20
, pp. 7243-7249
-
-
Seeler, J.S.1
Dejean, A.2
-
25
-
-
0036792683
-
Transcription factor Sp3 is silenced through SUMO modification by PIAS1
-
Sapetschnig A., et al. Transcription factor Sp3 is silenced through SUMO modification by PIAS1. EMBO J. 21:2002;5206-5215.
-
(2002)
EMBO J.
, vol.21
, pp. 5206-5215
-
-
Sapetschnig, A.1
-
26
-
-
0036809115
-
SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization
-
Ross S., et al. SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Mol. Cell. 10:2002;831-842.
-
(2002)
Mol. Cell
, vol.10
, pp. 831-842
-
-
Ross, S.1
-
27
-
-
0034993496
-
The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family
-
Hari K.L., et al. The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family. Genes Dev. 15:2001;1334-1348.
-
(2001)
Genes Dev.
, vol.15
, pp. 1334-1348
-
-
Hari, K.L.1
-
28
-
-
0036291014
-
The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II
-
Bachant J., et al. The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol. Cell. 9:2002;1169-1182.
-
(2002)
Mol. Cell
, vol.9
, pp. 1169-1182
-
-
Bachant, J.1
-
29
-
-
0036080376
-
Regulated SUMOylation and ubiquitination of DdMEK1 is required for proper chemotaxis
-
Sobko A., et al. Regulated SUMOylation and ubiquitination of DdMEK1 is required for proper chemotaxis. Dev. Cell. 2:2002;745-756.
-
(2002)
Dev. Cell
, vol.2
, pp. 745-756
-
-
Sobko, A.1
-
30
-
-
17844411190
-
NEDD8 recruits E2-ubiquitin to SCF E3 ligase
-
Kawakami T., et al. NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J. 20:2001;4003-4012.
-
(2001)
EMBO J.
, vol.20
, pp. 4003-4012
-
-
Kawakami, T.1
-
31
-
-
0037016754
-
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34
-
Wu K., et al. The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34. J. Biol. Chem. 277:2002;516-527.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 516-527
-
-
Wu, K.1
-
32
-
-
0036929129
-
CAND1, an inhibitor of CUL1-SKP1 binding and SCF ligases
-
CAND1, an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol. Cell. 10:2002;1511-1518.
-
(2002)
Mol. Cell
, vol.10
, pp. 1511-1518
-
-
Liu, J.1
-
33
-
-
0036924046
-
CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex
-
Zheng J., et al. CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Mol. Cell. 10:2002;1519-1526.
-
(2002)
Mol. Cell
, vol.10
, pp. 1519-1526
-
-
Zheng, J.1
-
34
-
-
0032993486
-
Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human
-
Wei N., Deng X.W. Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human. Trends Genet. 15:1999;98-103.
-
(1999)
Trends Genet.
, vol.15
, pp. 98-103
-
-
Wei, N.1
Deng, X.W.2
-
35
-
-
0037131242
-
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
-
Cope G.A., et al. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science. 298:2002;608-611.
-
(2002)
Science
, vol.298
, pp. 608-611
-
-
Cope, G.A.1
-
36
-
-
0035907047
-
Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response
-
Schwechheimer C., et al. Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science. 292:2001;1379-1382.
-
(2001)
Science
, vol.292
, pp. 1379-1382
-
-
Schwechheimer, C.1
-
37
-
-
0035906430
-
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome
-
Lyapina S., et al. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science. 292:2001;1382-1385.
-
(2001)
Science
, vol.292
, pp. 1382-1385
-
-
Lyapina, S.1
-
38
-
-
0023160888
-
Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin
-
Haas A.L., et al. Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. J. Biol. Chem. 262:1987;11315-11323.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 11315-11323
-
-
Haas, A.L.1
-
39
-
-
0037155882
-
UBP43 (USP18) specifically removes ISG15 from conjugated proteins
-
Malakhov M.P., et al. UBP43 (USP18) specifically removes ISG15 from conjugated proteins. J. Biol. Chem. 277:2002;9976-9981.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9976-9981
-
-
Malakhov, M.P.1
-
40
-
-
0035253852
-
Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein
-
Yuan W., Krug R.M. Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein. EMBO J. 20:2001;362-371.
-
(2001)
EMBO J.
, vol.20
, pp. 362-371
-
-
Yuan, W.1
Krug, R.M.2
-
41
-
-
0037443090
-
Protein ISGylation modulates the JAK-STAT signaling pathway
-
Malakhova O.A., et al. Protein ISGylation modulates the JAK-STAT signaling pathway. Genes Dev. 17:2003;455-460.
-
(2003)
Genes Dev.
, vol.17
, pp. 455-460
-
-
Malakhova, O.A.1
-
42
-
-
0036714980
-
Dysregulation of protein modification by ISG15 results in brain cell injury
-
Ritchie K.J., et al. Dysregulation of protein modification by ISG15 results in brain cell injury. Genes Dev. 16:2002;2207-2212.
-
(2002)
Genes Dev.
, vol.16
, pp. 2207-2212
-
-
Ritchie, K.J.1
-
43
-
-
0032934989
-
A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation
-
Liu L.Q., et al. A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation. Mol. Cell. Biol. 19:1999;3029-3038.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3029-3038
-
-
Liu, L.Q.1
-
44
-
-
0034011422
-
The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines
-
McLaughlin P.M., et al. The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines. Int. J. Cancer. 85:2000;871-876.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 871-876
-
-
McLaughlin, P.M.1
-
45
-
-
0034682843
-
Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p
-
Paz Y., et al. Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p. J. Biol. Chem. 275:2000;25445-25450.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25445-25450
-
-
Paz, Y.1
-
46
-
-
0032567528
-
Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes
-
Whitby F.G., et al. Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes. J. Biol. Chem. 273:1998;34983-34991.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34983-34991
-
-
Whitby, F.G.1
-
47
-
-
0035824559
-
Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1
-
Kamitani T., et al. Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1. J. Biol. Chem. 276:2001;46655-46660.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46655-46660
-
-
Kamitani, T.1
-
48
-
-
0037023716
-
Recognition of specific ubiquitin conjugates is important for the proteolytic functions of the ubiquitin-associated domain proteins Dsk2 and Rad23
-
Rao H., Sastry A. Recognition of specific ubiquitin conjugates is important for the proteolytic functions of the ubiquitin-associated domain proteins Dsk2 and Rad23. J. Biol. Chem. 277:2002;11691-11695.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11691-11695
-
-
Rao, H.1
Sastry, A.2
-
49
-
-
0037449715
-
Proteasomes modulate conjugation to the ubiquitin-like protein, ISG15
-
Liu M., et al. Proteasomes modulate conjugation to the ubiquitin-like protein, ISG15. J. Biol. Chem. 278:2003;1594-1602.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1594-1602
-
-
Liu, M.1
-
50
-
-
0036753547
-
Control of Smad7 stability by competition between acetylation and ubiquitination
-
Gronroos E., et al. Control of Smad7 stability by competition between acetylation and ubiquitination. Mol. Cell. 10:2002;483-493.
-
(2002)
Mol. Cell
, vol.10
, pp. 483-493
-
-
Gronroos, E.1
-
51
-
-
0035293622
-
Protein regulation by monoubiquitin
-
Hicke L. Protein regulation by monoubiquitin. Nat. Rev. Mol. Cell Biol. 2:2001;195-201.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 195-201
-
-
Hicke, L.1
-
52
-
-
0037193469
-
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation
-
Lindsten K., et al. Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation. J. Cell Biol. 157:2002;417-427.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 417-427
-
-
Lindsten, K.1
-
53
-
-
0035292759
-
Themes and variations on ubiquitylation
-
Weissman A.M. Themes and variations on ubiquitylation. Nat. Rev. Mol. Cell Biol. 2:2001;169-178.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 169-178
-
-
Weissman, A.M.1
-
54
-
-
0038128204
-
High-throughput immunoblotting: Ubiquitin-like protein ISG15 modifies key regulators of signal transduction
-
Malakhov M.P., et al. High-throughput immunoblotting: ubiquitin-like protein ISG15 modifies key regulators of signal transduction. J. Biol. Chem. 278:2003;16608-16613.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16608-16613
-
-
Malakhov, M.P.1
-
55
-
-
0037192523
-
Role of a ubiquitin-like modification in polarized morphogenesis
-
Dittmar G.A., et al. Role of a ubiquitin-like modification in polarized morphogenesis. Science. 295:2002;2442-2446.
-
(2002)
Science
, vol.295
, pp. 2442-2446
-
-
Dittmar, G.A.1
-
56
-
-
0035929607
-
The ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosis
-
Raasi S., et al. The ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosis. J. Biol. Chem. 276:2001;35334-35343.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35334-35343
-
-
Raasi, S.1
-
57
-
-
0032032399
-
Ubiquitin-like polypeptide conjugates to acceptor proteins in concanavalin A- and interferon γ-stimulated T-cells
-
Nakamura M., Tanigawa Y. Ubiquitin-like polypeptide conjugates to acceptor proteins in concanavalin A- and interferon γ-stimulated T-cells. Biochem. J. 330:1998;683-688.
-
(1998)
Biochem. J.
, vol.330
, pp. 683-688
-
-
Nakamura, M.1
Tanigawa, Y.2
-
58
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
Tatham M.H., et al. Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. 276:2001;35368-35374.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
-
59
-
-
18344391432
-
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
-
Zheng N., et al. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature. 416:2002;703-709.
-
(2002)
Nature
, vol.416
, pp. 703-709
-
-
Zheng, N.1
-
60
-
-
0032567404
-
The rub family of ubiquitin-like proteins. Crystal structure of Arabidopsis rub1 and expression of multiple rubs in Arabidopsis
-
Rao-Naik C., et al. The rub family of ubiquitin-like proteins. Crystal structure of Arabidopsis rub1 and expression of multiple rubs in Arabidopsis. J. Biol. Chem. 273:1998;34976-34982.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34976-34982
-
-
Rao-Naik, C.1
|