메뉴 건너뛰기




Volumn 4, Issue FRB, 2013, Pages

Pro-inflammatory signaling by IL-10 and IL-22: Bad habit stirred up by interferons?

Author keywords

Inflammation; Interleukin 10; Interleukin 22; Signal transducer and activator of transcription; Type I interferons

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CD4 ANTIGEN; CD8 ANTIGEN; CXCL1 CHEMOKINE; CXCL9 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 22; INTERLEUKIN 6; INTERLEUKIN 8; PLACEBO; RECOMBINANT INTERLEUKIN 10; STAT1 PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84878321565     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00018     Document Type: Article
Times cited : (69)

References (162)
  • 1
    • 33749345768 scopus 로고    scopus 로고
    • Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages
    • Antoniv, T. T., and Ivashkiv, L. B. (2006). Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages. Arthritis Rheum. 54, 2711-2721.
    • (2006) Arthritis Rheum. , vol.54 , pp. 2711-2721
    • Antoniv, T.T.1    Ivashkiv, L.B.2
  • 2
    • 40049098958 scopus 로고    scopus 로고
    • IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
    • Aujla, S. J., Chan, Y. R., Zheng, M., Fei, M., Askew, D. J., Pociask, D. A., et al. (2008). IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med. 14, 275-281.
    • (2008) Nat. Med. , vol.14 , pp. 275-281
    • Aujla, S.J.1    Chan, Y.R.2    Zheng, M.3    Fei, M.4    Askew, D.J.5    Pociask, D.A.6
  • 3
    • 67349275024 scopus 로고    scopus 로고
    • IL-22: a critical mediator in mucosal host defense
    • Aujla, S. J., and Kolls, J. K. (2009). IL-22: a critical mediator in mucosal host defense. J. Mol. Med. 87, 451-454.
    • (2009) J. Mol. Med. , vol.87 , pp. 451-454
    • Aujla, S.J.1    Kolls, J.K.2
  • 4
    • 77950534540 scopus 로고    scopus 로고
    • T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis
    • Axtell, R. C., de Jong, B. A., Boniface, K., van der Voort, L. F., Bhat, R., De Sarno, P., et al. (2010). T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat. Med. 16, 406-412.
    • (2010) Nat. Med. , vol.16 , pp. 406-412
    • Axtell, R.C.1    de Jong, B.A.2    Boniface, K.3    van der Voort, L.F.4    Bhat, R.5    De Sarno, P.6
  • 5
    • 84877608868 scopus 로고    scopus 로고
    • Type I interferons: beneficial in Th1 and detrimental in Th17 autoimmunity
    • (in press)
    • Axtell, R. C., Raman, C., and Steinman, L. (2012). Type I interferons: beneficial in Th1 and detrimental in Th17 autoimmunity. Clin. Rev. Allergy Immunol. (in press).
    • (2012) Clin. Rev. Allergy Immunol.
    • Axtell, R.C.1    Raman, C.2    Steinman, L.3
  • 6
    • 78449251677 scopus 로고    scopus 로고
    • Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1
    • doi:10.1371/journal.ppat.1001144
    • Bachmann, M., Horn, K., Rudloff, I., Goren, I., Holdener, M., Christen, U., et al. (2010). Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1. PLoS Pathog. 6:e1001144. doi:10.1371/journal.ppat.1001144
    • (2010) PLoS Pathog , vol.6
    • Bachmann, M.1    Horn, K.2    Rudloff, I.3    Goren, I.4    Holdener, M.5    Christen, U.6
  • 7
    • 84872675121 scopus 로고    scopus 로고
    • IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets
    • doi:10.1016/j.bcp.2012.11.004
    • Bachmann, M., Ulziibat, S., Härdle, L., Pfeilschifter, J., and Mühl, H. (2012). IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets. Biochem. Pharmacol. doi:10.1016/j.bcp.2012.11.004
    • (2012) Biochem. Pharmacol
    • Bachmann, M.1    Ulziibat, S.2    Härdle, L.3    Pfeilschifter, J.4    Mühl, H.5
  • 8
    • 0036695207 scopus 로고    scopus 로고
    • The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS)
    • Beebe, A. M., Cua, D. J., and de Waal Malefyt, R. (2002). The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS). Cytokine Growth Factor Rev. 13, 403-412.
    • (2002) Cytokine Growth Factor Rev. , vol.13 , pp. 403-412
    • Beebe, A.M.1    Cua, D.J.2    de Waal Malefyt, R.3
  • 9
    • 0345447697 scopus 로고    scopus 로고
    • Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen
    • Berg, R. E., Crossley, E., Murray, S., and Forman, J. (2003). Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen. J. Exp. Med. 198, 1583-1593.
    • (2003) J. Exp. Med. , vol.198 , pp. 1583-1593
    • Berg, R.E.1    Crossley, E.2    Murray, S.3    Forman, J.4
  • 10
    • 3843104695 scopus 로고    scopus 로고
    • Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity
    • Bhattacharyya, S., Sen, P., Wallet, M., Long, B., Baldwin, A. S. Jr., and Tisch, R. (2004). Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. Blood 104, 1100-1109.
    • (2004) Blood , vol.104 , pp. 1100-1109
    • Bhattacharyya, S.1    Sen, P.2    Wallet, M.3    Long, B.4    Baldwin Jr., A.S.5    Tisch, R.6
  • 11
    • 77953537389 scopus 로고    scopus 로고
    • Th17 cytokines and the gut mucosal barrier
    • Blaschitz, C., and Raffatellu, M. (2010). Th17 cytokines and the gut mucosal barrier. J. Clin. Immunol. 30, 196-203.
    • (2010) J. Clin. Immunol. , vol.30 , pp. 196-203
    • Blaschitz, C.1    Raffatellu, M.2
  • 12
    • 14844342604 scopus 로고    scopus 로고
    • IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
    • Boniface, K., Bernard, F. X., Garcia, M., Gurney, A. L., Lecron, J. C., and Morel, F. (2005). IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J. Immunol. 174, 3695-3702.
    • (2005) J. Immunol. , vol.174 , pp. 3695-3702
    • Boniface, K.1    Bernard, F.X.2    Garcia, M.3    Gurney, A.L.4    Lecron, J.C.5    Morel, F.6
  • 14
    • 33645829078 scopus 로고    scopus 로고
    • IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
    • Brand, S., Beigel, F., Olszak, T., Zitzmann, K., Eichhorst, S. T., Otte, J. M., et al. (2006). IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G827-G838.
    • (2006) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.290
    • Brand, S.1    Beigel, F.2    Olszak, T.3    Zitzmann, K.4    Eichhorst, S.T.5    Otte, J.M.6
  • 15
    • 0032705236 scopus 로고    scopus 로고
    • Interleukin 10 and arthritis
    • Brennan, F. M. (1999). Interleukin 10 and arthritis. Rheumatology 38, 293-297.
    • (1999) Rheumatology , vol.38 , pp. 293-297
    • Brennan, F.M.1
  • 16
    • 79952052483 scopus 로고    scopus 로고
    • Recombinant human interleukin 10 for induction of remission in Crohn's disease
    • Buruiana, F. E., Solá, I., and Alonso-Coello, P. (2010). Recombinant human interleukin 10 for induction of remission in Crohn's disease. Cochrane Database Syst. Rev. 2010, CD005109.
    • (2010) Cochrane Database Syst. Rev. , vol.2010
    • Buruiana, F.E.1    Solá, I.2    Alonso-Coello, P.3
  • 17
    • 0033376777 scopus 로고    scopus 로고
    • IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18
    • Cai, G., Kastelein, R. A., and Hunter, C. A. (1999). IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18. Eur. J. Immunol. 29, 2658-2665.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2658-2665
    • Cai, G.1    Kastelein, R.A.2    Hunter, C.A.3
  • 19
    • 35649014170 scopus 로고    scopus 로고
    • Interferon-based therapy of hepatitis C
    • Chevaliez, S., and Pawlotsky, J. M. (2007). Interferon-based therapy of hepatitis C. Adv. Drug Deliv. Rev. 59, 1222-1241.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1222-1241
    • Chevaliez, S.1    Pawlotsky, J.M.2
  • 20
    • 68249137286 scopus 로고    scopus 로고
    • Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity
    • Colonna, M. (2009). Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity. Immunity 31, 15-23.
    • (2009) Immunity , vol.31 , pp. 15-23
    • Colonna, M.1
  • 21
    • 0033958548 scopus 로고    scopus 로고
    • Recombinant human interleukin-10 fails to alter proinflammatory cytokine production or physiologic changes associated with the Jarisch-Herxheimer reaction
    • Cooper, P. J., Fekade, D., Remick, D. G., Grint, P., Wherry, J., and Griffin, G. E. (2000). Recombinant human interleukin-10 fails to alter proinflammatory cytokine production or physiologic changes associated with the Jarisch-Herxheimer reaction. J. Infect. Dis. 181, 203-209.
    • (2000) J. Infect. Dis. , vol.181 , pp. 203-209
    • Cooper, P.J.1    Fekade, D.2    Remick, D.G.3    Grint, P.4    Wherry, J.5    Griffin, G.E.6
  • 22
    • 0035313447 scopus 로고    scopus 로고
    • Regulatory activity of autocrine IL-10 on dendritic cell functions
    • Corinti, S., Albanesi, C., la Sala, A., Pastore, S., and Girolomoni, G. (2001). Regulatory activity of autocrine IL-10 on dendritic cell functions. J. Immunol. 166, 4312-4318.
    • (2001) J. Immunol. , vol.166 , pp. 4312-4318
    • Corinti, S.1    Albanesi, C.2    la Sala, A.3    Pastore, S.4    Girolomoni, G.5
  • 24
    • 39549094473 scopus 로고    scopus 로고
    • Biological agents for ulcerative colitis: hypes and hopes
    • Danese, S., Angelucci, E., Malesci, A., and Caprilli, R. (2008). Biological agents for ulcerative colitis: hypes and hopes. Med. Res. Rev. 28, 201-218.
    • (2008) Med. Res. Rev. , vol.28 , pp. 201-218
    • Danese, S.1    Angelucci, E.2    Malesci, A.3    Caprilli, R.4
  • 25
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., and de Vries, J. E. (1991). Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174, 1209-1220.
    • (1991) J. Exp. Med. , vol.174 , pp. 1209-1220
    • de Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 26
    • 34547116656 scopus 로고    scopus 로고
    • Type I interferon receptors: biochemistry and biological functions
    • de Weerd, N. A., Samarajiwa, S. A., and Hertzog, P. J. (2007). Type I interferon receptors: biochemistry and biological functions. J. Biol. Chem. 282, 20053-20057.
    • (2007) J. Biol. Chem. , vol.282 , pp. 20053-20057
    • de Weerd, N.A.1    Samarajiwa, S.A.2    Hertzog, P.J.3
  • 27
    • 61549132582 scopus 로고    scopus 로고
    • Comprehensive biomarker monitoring in cytokine therapy: heterogeneous, time-dependent, and persisting immune effects of interleukin-10 application in psoriasis
    • Döcke, W. D., Asadullah, K., Belbe, G., Ebeling, M., Höflich, C., Friedrich, M., et al. (2009). Comprehensive biomarker monitoring in cytokine therapy: heterogeneous, time-dependent, and persisting immune effects of interleukin-10 application in psoriasis. J. Leukoc. Biol. 85, 582-593.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 582-593
    • Döcke, W.D.1    Asadullah, K.2    Belbe, G.3    Ebeling, M.4    Höflich, C.5    Friedrich, M.6
  • 28
    • 0033848094 scopus 로고    scopus 로고
    • Exacerbation of psoriasis by interferon-alpha therapy for hepatitis C
    • Downs, A. M., and Dunnill, M. G. (2000). Exacerbation of psoriasis by interferon-alpha therapy for hepatitis C. Clin. Exp. Dermatol. 25, 351-352.
    • (2000) Clin. Exp. Dermatol. , vol.25 , pp. 351-352
    • Downs, A.M.1    Dunnill, M.G.2
  • 29
    • 0029993786 scopus 로고    scopus 로고
    • Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12
    • Duchmann, R., Schmitt, E., Knolle, P., Meyerzum Büschenfelde, K. H., and Neurath, M. (1996). Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur. J. Immunol. 26, 934-938.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 934-938
    • Duchmann, R.1    Schmitt, E.2    Knolle, P.3    Meyerzum Büschenfelde, K.H.4    Neurath, M.5
  • 30
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen, T., Geiger, R., Jarrossay, D., Lanzavecchia, A., and Sallusto, F. (2009). Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol. 10, 857-863.
    • (2009) Nat. Immunol. , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3    Lanzavecchia, A.4    Sallusto, F.5
  • 31
    • 79953066237 scopus 로고    scopus 로고
    • IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality
    • Dumoutier, L., de Heusch, M., Orabona, C., Satoh-Takayama, N., Eberl, G., Sirard, J. C., et al. (2011). IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. Eur. J. Immunol. 41, 1075-1085.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1075-1085
    • Dumoutier, L.1    de Heusch, M.2    Orabona, C.3    Satoh-Takayama, N.4    Eberl, G.5    Sirard, J.C.6
  • 32
    • 0034565220 scopus 로고    scopus 로고
    • IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes
    • Dumoutier, L., Van Roost, E., Ameye, G., Michaux, L., and Renauld, J. C. (2000). IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes. Genes Immun. 1, 488-494.
    • (2000) Genes Immun. , vol.1 , pp. 488-494
    • Dumoutier, L.1    Van Roost, E.2    Ameye, G.3    Michaux, L.4    Renauld, J.C.5
  • 33
    • 84865296753 scopus 로고    scopus 로고
    • Host defenses against bacterial lower respiratory tract infection
    • Eddens, T., and Kolls, J. K. (2012). Host defenses against bacterial lower respiratory tract infection. Curr. Opin. Immunol. 24, 424-430.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 424-430
    • Eddens, T.1    Kolls, J.K.2
  • 34
    • 79960644751 scopus 로고    scopus 로고
    • Interferon-α in the generation of monocyte-derived dendritic cells: recent advances and implications for dermatology
    • Farkas, A., and Kemény, L. (2011). Interferon-α in the generation of monocyte-derived dendritic cells: recent advances and implications for dermatology. Br. J. Dermatol. 165, 247-254.
    • (2011) Br. J. Dermatol. , vol.165 , pp. 247-254
    • Farkas, A.1    Kemény, L.2
  • 35
    • 84862769727 scopus 로고    scopus 로고
    • Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection
    • Feng, D., Kong, X., Weng, H., Park, O., Wang, H., Dooley, S., et al. (2012). Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection. Gastroenterology 143, 188-198.
    • (2012) Gastroenterology , vol.143 , pp. 188-198
    • Feng, D.1    Kong, X.2    Weng, H.3    Park, O.4    Wang, H.5    Dooley, S.6
  • 36
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.
    • Fiorentino, D. F., Bond, M. W., and Mosmann, T. R. (1989). Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170, 2081-2095.
    • (1989) J. Exp. Med. , vol.170 , pp. 2081-2095
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 38
    • 0036224092 scopus 로고    scopus 로고
    • Immunomodulation by interleukin-10 therapy decreases the incidence of relapse and prolongs the relapse-free interval in psoriasis
    • Friedrich, M., Döcke, W. D., Klein, A., Philipp, S., Volk, H. D., Sterry, W., et al. (2002). Immunomodulation by interleukin-10 therapy decreases the incidence of relapse and prolongs the relapse-free interval in psoriasis. J. Invest. Dermatol. 118, 672-677.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 672-677
    • Friedrich, M.1    Döcke, W.D.2    Klein, A.3    Philipp, S.4    Volk, H.D.5    Sterry, W.6
  • 39
    • 0028180701 scopus 로고
    • Role of endogenous interferon-beta in lipopolysaccharide-triggered activation of the inducible nitric-oxide synthase gene in a mouse macrophage cell line, J774
    • Fujihara, M., Ito, N., Pace, J. L., Watanabe, Y., Russell, S. W., and Suzuki, T. (1994). Role of endogenous interferon-beta in lipopolysaccharide-triggered activation of the inducible nitric-oxide synthase gene in a mouse macrophage cell line, J774. J. Biol. Chem. 269, 12773-12778.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12773-12778
    • Fujihara, M.1    Ito, N.2    Pace, J.L.3    Watanabe, Y.4    Russell, S.W.5    Suzuki, T.6
  • 40
    • 59649086053 scopus 로고    scopus 로고
    • Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice
    • Geboes, L., Dumoutier, L., Kelchtermans, H., Schurgers, E., Mitera, T., Renauld, J. C., et al. (2009). Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice. Arthritis Rheum. 60, 390-395.
    • (2009) Arthritis Rheum. , vol.60 , pp. 390-395
    • Geboes, L.1    Dumoutier, L.2    Kelchtermans, H.3    Schurgers, E.4    Mitera, T.5    Renauld, J.C.6
  • 43
    • 84857415635 scopus 로고    scopus 로고
    • Constitutive type I interferon modulates homeostatic balance through tonic signaling
    • Gough, D. J., Messina, N. L., Clarke, C. J., Johnstone, R. W., and Levy, D. E. (2012). Constitutive type I interferon modulates homeostatic balance through tonic signaling. Immunity 36, 166-174.
    • (2012) Immunity , vol.36 , pp. 166-174
    • Gough, D.J.1    Messina, N.L.2    Clarke, C.J.3    Johnstone, R.W.4    Levy, D.E.5
  • 44
    • 77951753459 scopus 로고    scopus 로고
    • Functional crosstalk between type I and II interferon through the regulated expression of STAT1
    • doi:10.1371/journal.pbio.1000361
    • Gough, D. J., Messina, N. L., Hii, L., Gould, J. A., Sabapathy, K., Robertson, A. P., et al. (2010). Functional crosstalk between type I and II interferon through the regulated expression of STAT1. PLoS Biol. 8:e1000361. doi:10.1371/journal.pbio.1000361
    • (2010) PLoS Biol. , vol.8
    • Gough, D.J.1    Messina, N.L.2    Hii, L.3    Gould, J.A.4    Sabapathy, K.5    Robertson, A.P.6
  • 45
    • 79951740151 scopus 로고    scopus 로고
    • Type I interferon inhibits interleukin-1 production and inflammasome activation
    • Guarda, G., Braun, M., Staehli, F., Tardivel, A., Mattmann, C., Förster, I., et al. (2011). Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34, 213-223.
    • (2011) Immunity , vol.34 , pp. 213-223
    • Guarda, G.1    Braun, M.2    Staehli, F.3    Tardivel, A.4    Mattmann, C.5    Förster, I.6
  • 46
    • 43049101640 scopus 로고    scopus 로고
    • The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
    • Guo, B., Chang, E. Y., and Cheng, G. (2008). The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest. 118, 1680-1690.
    • (2008) J. Clin. Invest. , vol.118 , pp. 1680-1690
    • Guo, B.1    Chang, E.Y.2    Cheng, G.3
  • 47
  • 48
    • 0242412335 scopus 로고    scopus 로고
    • Reprogramming of IL-10 activity and signaling by IFN-gamma
    • Herrero, C., Hu, X., Li, W. P., Samuels, S., Sharif, M. N., Kotenko, S., et al. (2003). Reprogramming of IL-10 activity and signaling by IFN-gamma. J. Immunol. 171, 5034-5041.
    • (2003) J. Immunol. , vol.171 , pp. 5034-5041
    • Herrero, C.1    Hu, X.2    Li, W.P.3    Samuels, S.4    Sharif, M.N.5    Kotenko, S.6
  • 49
    • 0033635304 scopus 로고    scopus 로고
    • CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling
    • Hida, S., Ogasawara, K., Sato, K., Abe, M., Takayanagi, H., Yokochi, T., et al. (2000). CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling. Immunity 13, 643-655.
    • (2000) Immunity , vol.13 , pp. 643-655
    • Hida, S.1    Ogasawara, K.2    Sato, K.3    Abe, M.4    Takayanagi, H.5    Yokochi, T.6
  • 51
    • 84859777122 scopus 로고    scopus 로고
    • Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury
    • Hofmann, S. R., Rösen-Wolff, A., Tsokos, G. C., and Hedrich, C. M. (2012). Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury. Clin. Immunol. 143, 116-127.
    • (2012) Clin. Immunol. , vol.143 , pp. 116-127
    • Hofmann, S.R.1    Rösen-Wolff, A.2    Tsokos, G.C.3    Hedrich, C.M.4
  • 52
    • 26444502974 scopus 로고    scopus 로고
    • Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat
    • Hofstetter, C., Flondor, M., Hoegl, S., Muhl, H., and Zwissler, B. (2005). Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat. Crit. Care Med. 33, 2317-2322.
    • (2005) Crit. Care Med. , vol.33 , pp. 2317-2322
    • Hofstetter, C.1    Flondor, M.2    Hoegl, S.3    Muhl, H.4    Zwissler, B.5
  • 53
    • 0021264311 scopus 로고
    • Immune response-associated production of neopterin.Release from macrophages primarily under control of interferon-gamma.
    • Huber, C., Batchelor, J. R., Fuchs, D., Hausen, A., Lang, A., Niederwieser, D., et al. (1984). Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma. J. Exp. Med. 160, 310-316.
    • (1984) J. Exp. Med. , vol.160 , pp. 310-316
    • Huber, C.1    Batchelor, J.R.2    Fuchs, D.3    Hausen, A.4    Lang, A.5    Niederwieser, D.6
  • 54
    • 17244381180 scopus 로고    scopus 로고
    • Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine
    • Ikeuchi, H., Kuroiwa, T., Hiramatsu, N., Kaneko, Y., Hiromura, K., Ueki, K., et al. (2005). Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum. 52, 1037-1046.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1037-1046
    • Ikeuchi, H.1    Kuroiwa, T.2    Hiramatsu, N.3    Kaneko, Y.4    Hiromura, K.5    Ueki, K.6
  • 55
    • 0033071049 scopus 로고    scopus 로고
    • Interleukin-12 production by human alveolar macrophages is controlled by the autocrine production of interleukin-10
    • Isler, P., de Rochemonteix, B. G., Songeon, F., Boehringer, N., and Nicod, L. P. (1999). Interleukin-12 production by human alveolar macrophages is controlled by the autocrine production of interleukin-10. Am. J. Respir. Cell Mol. Biol. 20, 270-278.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.20 , pp. 270-278
    • Isler, P.1    de Rochemonteix, B.G.2    Songeon, F.3    Boehringer, N.4    Nicod, L.P.5
  • 56
    • 0033104946 scopus 로고    scopus 로고
    • Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1
    • Ito, S., Ansari, P., Sakatsume, M., Dickensheets, H., Vazquez, N., Donnelly, R. P., et al. (1999). Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1. Blood 93, 1456-1463.
    • (1999) Blood , vol.93 , pp. 1456-1463
    • Ito, S.1    Ansari, P.2    Sakatsume, M.3    Dickensheets, H.4    Vazquez, N.5    Donnelly, R.P.6
  • 57
    • 0344665752 scopus 로고    scopus 로고
    • Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesis
    • Ivashkiv, L. B. (2003). Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesis. Autoimmunity 36, 473-479.
    • (2003) Autoimmunity , vol.36 , pp. 473-479
    • Ivashkiv, L.B.1
  • 58
    • 0031873471 scopus 로고    scopus 로고
    • IL-10 up-regulates nitric oxide (NO) synthesis by lipopolysaccharide (LPS)-activated macrophages: improved control of Trypanosoma cruzi infection
    • Jacobs, F., Chaussabel, D., Truyens, C., Leclerq, V., Carlier, Y., Goldman, M., et al. (1998). IL-10 up-regulates nitric oxide (NO) synthesis by lipopolysaccharide (LPS)-activated macrophages: improved control of Trypanosoma cruzi infection. Clin. Exp. Immunol. 113, 59-64.
    • (1998) Clin. Exp. Immunol. , vol.113 , pp. 59-64
    • Jacobs, F.1    Chaussabel, D.2    Truyens, C.3    Leclerq, V.4    Carlier, Y.5    Goldman, M.6
  • 59
    • 77954156529 scopus 로고    scopus 로고
    • Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?
    • Jarnicki, A., Putoczki, T., and Ernst, M. (2010). Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling? Cell Div. 5, 14.
    • (2010) Cell Div , vol.5 , pp. 14
    • Jarnicki, A.1    Putoczki, T.2    Ernst, M.3
  • 60
    • 0036138869 scopus 로고    scopus 로고
    • Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis
    • John, M., Oltmanns, U., Fietze, I., Witt, C., and Jung, K. (2002). Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis. Exp. Lung Res. 28, 55-68.
    • (2002) Exp. Lung Res. , vol.28 , pp. 55-68
    • John, M.1    Oltmanns, U.2    Fietze, I.3    Witt, C.4    Jung, K.5
  • 61
    • 78651414618 scopus 로고    scopus 로고
    • Overview of the biology of type I interferons
    • Kalliolias, G. D., and Ivashkiv, L. B. (2010). Overview of the biology of type I interferons. Arthritis Res. Ther. 12(Suppl. 1), :S1.
    • (2010) Arthritis Res. Ther. , vol.12 , Issue.SUPPL. 1
    • Kalliolias, G.D.1    Ivashkiv, L.B.2
  • 62
    • 84856400515 scopus 로고    scopus 로고
    • Interferon signals and monocytic sensitization of the interferon-γ signaling pathway in the peripheral blood of patients with rheumatoid arthritis
    • Karonitsch, T., von Dalwigk, K., Steiner, C. W., Blüml, S., Steiner, G., Kiener, H. P., et al. (2012). Interferon signals and monocytic sensitization of the interferon-γ signaling pathway in the peripheral blood of patients with rheumatoid arthritis. Arthritis Rheum. 64, 400-408.
    • (2012) Arthritis Rheum. , vol.64 , pp. 400-408
    • Karonitsch, T.1    von Dalwigk, K.2    Steiner, C.W.3    Blüml, S.4    Steiner, G.5    Kiener, H.P.6
  • 63
    • 0036379347 scopus 로고    scopus 로고
    • Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients
    • Kaser, A., Novick, D., Rubinstein, M., Siegmund, B., Enrich, B., Koch, R. O., et al. (2002). Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients. Clin. Exp. Immunol. 129, 332-338.
    • (2002) Clin. Exp. Immunol. , vol.129 , pp. 332-338
    • Kaser, A.1    Novick, D.2    Rubinstein, M.3    Siegmund, B.4    Enrich, B.5    Koch, R.O.6
  • 64
    • 14644403009 scopus 로고    scopus 로고
    • Toll-like receptor 9-induced type I IFN protects mice from experimental colitis
    • Katakura, K., Lee, J., Rachmilewitz, D., Li, G., Eckmann, L., and Raz, E. (2005). Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J. Clin. Invest. 115, 695-702.
    • (2005) J. Clin. Invest. , vol.115 , pp. 695-702
    • Katakura, K.1    Lee, J.2    Rachmilewitz, D.3    Li, G.4    Eckmann, L.5    Raz, E.6
  • 65
    • 84866173091 scopus 로고    scopus 로고
    • Interleukin-22 promotes osteoclastogenesis in rheumatoid arthritis through induction of RANKL in human synovial fibroblasts
    • Kim, K. W., Kim, H. R., Park, J. Y., Park, J. S., Oh, H. J., Woo, Y. J., et al. (2012). Interleukin-22 promotes osteoclastogenesis in rheumatoid arthritis through induction of RANKL in human synovial fibroblasts. Arthritis Rheum. 64, 1015-1023.
    • (2012) Arthritis Rheum. , vol.64 , pp. 1015-1023
    • Kim, K.W.1    Kim, H.R.2    Park, J.Y.3    Park, J.S.4    Oh, H.J.5    Woo, Y.J.6
  • 66
    • 0036792808 scopus 로고    scopus 로고
    • Clinical and immunologic assessment of patients with psoriasis in a randomized, double-blind, placebo-controlled trial using recombinant human interleukin 10
    • Kimball, A. B., Kawamura, T., Tejura, K., Boss, C., Hancox, A. R., Vogel, J. C., et al. (2002). Clinical and immunologic assessment of patients with psoriasis in a randomized, double-blind, placebo-controlled trial using recombinant human interleukin 10. Arch. Dermatol. 138, 1341-1346.
    • (2002) Arch. Dermatol. , vol.138 , pp. 1341-1346
    • Kimball, A.B.1    Kawamura, T.2    Tejura, K.3    Boss, C.4    Hancox, A.R.5    Vogel, J.C.6
  • 67
    • 0035898647 scopus 로고    scopus 로고
    • Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology
    • Kontoyiannis, D., Kotlyarov, A., Carballo, E., Alexopoulou, L., Blackshear, P. J., Gaestel, M., et al. (2001). Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO J. 20, 3760-3770.
    • (2001) EMBO J. , vol.20 , pp. 3760-3770
    • Kontoyiannis, D.1    Kotlyarov, A.2    Carballo, E.3    Alexopoulou, L.4    Blackshear, P.J.5    Gaestel, M.6
  • 68
    • 44949253997 scopus 로고    scopus 로고
    • Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity
    • Krumbholz, M., Faber, H., Steinmeyer, F., Hoffmann, L. A., Kümpfel, T., Pellkofer, H., et al. (2008). Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. Brain 131, 1455-1463.
    • (2008) Brain , vol.131 , pp. 1455-1463
    • Krumbholz, M.1    Faber, H.2    Steinmeyer, F.3    Hoffmann, L.A.4    Kümpfel, T.5    Pellkofer, H.6
  • 69
    • 84874203888 scopus 로고    scopus 로고
    • Transcriptional regulation of the anti-inflammatory cytokine IL-10 in acquired immune cells
    • doi:10.3389/fimmu.2012.00275
    • Kubo, M., and Motomura, Y. (2012). Transcriptional regulation of the anti-inflammatory cytokine IL-10 in acquired immune cells. Front. Immunol. 3:275. doi:10.3389/fimmu.2012.00275
    • (2012) Front. Immunol. , vol.3 , pp. 275
    • Kubo, M.1    Motomura, Y.2
  • 70
    • 0029994967 scopus 로고    scopus 로고
    • Suppression of superoxide anion production by interleukin-10 is accompanied by a downregulation of the genes for subunit proteins of NADPH oxidase
    • Kuga, S., Otsuka, T., Niiro, H., Nunoi, H., Nemoto, Y., Nakano, T., et al. (1996). Suppression of superoxide anion production by interleukin-10 is accompanied by a downregulation of the genes for subunit proteins of NADPH oxidase. Exp. Hematol. 24, 151-157.
    • (1996) Exp. Hematol. , vol.24 , pp. 151-157
    • Kuga, S.1    Otsuka, T.2    Niiro, H.3    Nunoi, H.4    Nemoto, Y.5    Nakano, T.6
  • 71
    • 0028982242 scopus 로고
    • Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders
    • Kulkarni, A. B., Ward, J. M., Yaswen, L., Mackall, C. L., Bauer, S. R., Huh, C. G., et al. (1995). Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders. Am. J. Pathol. 146, 264-275.
    • (1995) Am. J. Pathol. , vol.146 , pp. 264-275
    • Kulkarni, A.B.1    Ward, J.M.2    Yaswen, L.3    Mackall, C.L.4    Bauer, S.R.5    Huh, C.G.6
  • 72
    • 84867658823 scopus 로고    scopus 로고
    • IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection
    • Kumar, P., Thakar, M. S., Ouyang, W., and Malarkannan, S. (2013). IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection. Mucosal Immunol. 6, 69-82.
    • (2013) Mucosal Immunol. , vol.6 , pp. 69-82
    • Kumar, P.1    Thakar, M.S.2    Ouyang, W.3    Malarkannan, S.4
  • 73
    • 77955869446 scopus 로고    scopus 로고
    • Psoriasis during interferon beta treatment for multiple sclerosis
    • La Mantia, L., and Capsoni, F. (2010). Psoriasis during interferon beta treatment for multiple sclerosis. Neurol. Sci. 31, 337-339.
    • (2010) Neurol. Sci. , vol.31 , pp. 337-339
    • La Mantia, L.1    Capsoni, F.2
  • 75
    • 0035030376 scopus 로고    scopus 로고
    • Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • Le Bon, A., Schiavoni, G., D'Agostino, G., Gresser, I., Belardelli, F., and Tough, D. F. (2001). Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14, 461-470.
    • (2001) Immunity , vol.14 , pp. 461-470
    • Le Bon, A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, F.5    Tough, D.F.6
  • 76
    • 79959811817 scopus 로고    scopus 로고
    • Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis
    • Leipe, J., Schramm, M. A., Grunke, M., Baeuerle, M., Dechant, C., Nigg, A. P., et al. (2011). Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis. Ann. Rheum. Dis. 70, 1453-1457.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1453-1457
    • Leipe, J.1    Schramm, M.A.2    Grunke, M.3    Baeuerle, M.4    Dechant, C.5    Nigg, A.P.6
  • 77
    • 80053620170 scopus 로고    scopus 로고
    • Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response
    • Li, H. S., Gelbard, A., Martinez, G. J., Esashi, E., Zhang, H., Nguyen-Jackson, H., et al. (2011). Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response. Blood 118, 3879-3889.
    • (2011) Blood , vol.118 , pp. 3879-3889
    • Li, H.S.1    Gelbard, A.2    Martinez, G.J.3    Esashi, E.4    Zhang, H.5    Nguyen-Jackson, H.6
  • 78
    • 84865772924 scopus 로고    scopus 로고
    • Type I and III interferons enhance IL-10R expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12
    • Liu, B. S., Janssen, H. L., and Boonstra, A. (2012). Type I and III interferons enhance IL-10R expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12. Eur. J. Immunol. 42, 2431-2440.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 2431-2440
    • Liu, B.S.1    Janssen, H.L.2    Boonstra, A.3
  • 79
    • 0033883903 scopus 로고    scopus 로고
    • Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus
    • Llorente, L., Richaud-Patin, Y., García-Padilla, C., Claret, E., Jakez-Ocampo, J., Cardiel, M. H., et al. (2000). Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus. Arthritis Rheum. 43, 1790-1800.
    • (2000) Arthritis Rheum. , vol.43 , pp. 1790-1800
    • Llorente, L.1    Richaud-Patin, Y.2    García-Padilla, C.3    Claret, E.4    Jakez-Ocampo, J.5    Cardiel, M.H.6
  • 80
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • Mantovani, A., Cassatella, M. A., Costantini, C., and Jaillon, S. (2011). Neutrophils in the activation and regulation of innate and adaptive immunity. Nat. Rev. Immunol. 11, 519-531.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 81
    • 6344282903 scopus 로고    scopus 로고
    • Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation
    • Martinelli, S., Urosevic, M., Daryadel, A., Oberholzer, P. A., Baumann, C., Fey, M. F., et al. (2004). Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation. J. Biol. Chem. 279, 44123-44132.
    • (2004) J. Biol. Chem. , vol.279 , pp. 44123-44132
    • Martinelli, S.1    Urosevic, M.2    Daryadel, A.3    Oberholzer, P.A.4    Baumann, C.5    Fey, M.F.6
  • 82
    • 0034939227 scopus 로고    scopus 로고
    • IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12
    • Matikainen, S., Paananen, A., Miettinen, M., Kurimoto, M., Timonen, T., Julkunen, I., et al. (2001). IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12. Eur. J. Immunol. 31, 2236-2245.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2236-2245
    • Matikainen, S.1    Paananen, A.2    Miettinen, M.3    Kurimoto, M.4    Timonen, T.5    Julkunen, I.6
  • 83
    • 0032080850 scopus 로고    scopus 로고
    • Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development
    • McRae, B. L., Semnani, R. T., Hayes, M. P., and van Seventer, G. A. (1998). Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development. J. Immunol. 160, 4298-4304.
    • (1998) J. Immunol. , vol.160 , pp. 4298-4304
    • McRae, B.L.1    Semnani, R.T.2    Hayes, M.P.3    van Seventer, G.A.4
  • 84
    • 0032521024 scopus 로고    scopus 로고
    • Production of IL-10 by human natural killer cells stimulated with IL-2 and/or IL-12
    • Mehrotra, P. T., Donnelly, R. P., Wong, S., Kanegane, H., Geremew, A., Mostowski, H. S., et al. (1998). Production of IL-10 by human natural killer cells stimulated with IL-2 and/or IL-12. J. Immunol. 160, 2637-2644.
    • (1998) J. Immunol. , vol.160 , pp. 2637-2644
    • Mehrotra, P.T.1    Donnelly, R.P.2    Wong, S.3    Kanegane, H.4    Geremew, A.5    Mostowski, H.S.6
  • 85
    • 69349093225 scopus 로고    scopus 로고
    • Interleukin-17 and type 17 helper T cells
    • Miossec, P., Korn, T., and Kuchroo, V. K. (2009). Interleukin-17 and type 17 helper T cells. N. Engl. J. Med. 361, 888-898.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 888-898
    • Miossec, P.1    Korn, T.2    Kuchroo, V.K.3
  • 86
    • 0034884781 scopus 로고    scopus 로고
    • Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling
    • Mitani, Y., Takaoka, A., Kim, S. H., Kato, Y., Yokochi, T., Tanaka, N., et al. (2001). Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling. Genes Cells 6, 631-640.
    • (2001) Genes Cells , vol.6 , pp. 631-640
    • Mitani, Y.1    Takaoka, A.2    Kim, S.H.3    Kato, Y.4    Yokochi, T.5    Tanaka, N.6
  • 87
    • 79951471683 scopus 로고    scopus 로고
    • Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity
    • Mühl, H., Bachmann, M., and Pfeilschifter, J. (2011). Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity. Cell. Microbiol. 13, 340-348.
    • (2011) Cell. Microbiol. , vol.13 , pp. 340-348
    • Mühl, H.1    Bachmann, M.2    Pfeilschifter, J.3
  • 88
    • 83455173552 scopus 로고    scopus 로고
    • IL-10 elicits IFNγ-dependent tumor immune surveillance
    • Mumm, J. B., Emmerich, J., Zhang, X., Chan, I., Wu, L., Mauze, S., et al. (2011). IL-10 elicits IFNγ-dependent tumor immune surveillance. Cancer Cell 20, 781-796.
    • (2011) Cancer Cell , vol.20 , pp. 781-796
    • Mumm, J.B.1    Emmerich, J.2    Zhang, X.3    Chan, I.4    Wu, L.5    Mauze, S.6
  • 89
    • 79955897796 scopus 로고    scopus 로고
    • Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18
    • doi:10.1371/journal.pone.0018553
    • Munk, R. B., Sugiyama, K., Ghosh, P., Sasaki, C. Y., Rezanka, L., Banerjee, K., et al. (2011). Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18. PLoS ONE 6:e18553. doi:10.1371/journal.pone.0018553
    • (2011) PLoS ONE , vol.6
    • Munk, R.B.1    Sugiyama, K.2    Ghosh, P.3    Sasaki, C.Y.4    Rezanka, L.5    Banerjee, K.6
  • 91
    • 79960743033 scopus 로고    scopus 로고
    • Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients
    • Nakajima, H., Nakajima, K., Tarutani, M., Morishige, R., and Sano, S. (2011). Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients. Arch. Dermatol. Res. 303, 451-355.
    • (2011) Arch. Dermatol. Res. , vol.303 , pp. 451-355
    • Nakajima, H.1    Nakajima, K.2    Tarutani, M.3    Morishige, R.4    Sano, S.5
  • 92
    • 22344438901 scopus 로고    scopus 로고
    • Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production
    • Nestle, F. O., Conrad, C., Tun-Kyi, A., Homey, B., Gombert, M., Boyman, O., et al. (2005). Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J. Exp. Med. 202, 135-143.
    • (2005) J. Exp. Med. , vol.202 , pp. 135-143
    • Nestle, F.O.1    Conrad, C.2    Tun-Kyi, A.3    Homey, B.4    Gombert, M.5    Boyman, O.6
  • 94
    • 0037274904 scopus 로고    scopus 로고
    • IL-18 initiates release of matrix metalloproteinase-9 from peripheral blood mononuclear cells without affecting tissue inhibitor of matrix metalloproteinases-1: suppression by TNFalpha blockage and modulation by IL-10. Naunyn Schmiedebergs Arch.
    • Nold, M., Goede, A., Eberhardt, W., Pfeilschifter, J., and Mühl, H. (2003). IL-18 initiates release of matrix metalloproteinase-9 from peripheral blood mononuclear cells without affecting tissue inhibitor of matrix metalloproteinases-1: suppression by TNFalpha blockage and modulation by IL-10. Naunyn Schmiedebergs Arch. Pharmacol. 367, 68-75.
    • (2003) Pharmacol. , vol.367 , pp. 68-75
    • Nold, M.1    Goede, A.2    Eberhardt, W.3    Pfeilschifter, J.4    Mühl, H.5
  • 96
    • 0028299340 scopus 로고
    • The human interferon alpha/beta receptor: characterization and molecular cloning
    • Novick, D., Cohen, B., and Rubinstein, M. (1994). The human interferon alpha/beta receptor: characterization and molecular cloning. Cell 77, 391-400.
    • (1994) Cell , vol.77 , pp. 391-400
    • Novick, D.1    Cohen, B.2    Rubinstein, M.3
  • 97
    • 79953048089 scopus 로고    scopus 로고
    • Regulation and functions of the IL-10 family of cytokines in inflammation and disease
    • Ouyang, W., Rutz, S., Crellin, N. K., Valdez, P. A., and Hymowitz, S. G. (2011). Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu. Rev. Immunol. 29, 71-109.
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 71-109
    • Ouyang, W.1    Rutz, S.2    Crellin, N.K.3    Valdez, P.A.4    Hymowitz, S.G.5
  • 98
    • 84858587977 scopus 로고    scopus 로고
    • Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages
    • Paget, C., Ivanov, S., Fontaine, J., Renneson, J., Blanc, F., Pichavant, M., et al. (2012). Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. J. Biol. Chem. 287, 8816-8829.
    • (2012) J. Biol. Chem. , vol.287 , pp. 8816-8829
    • Paget, C.1    Ivanov, S.2    Fontaine, J.3    Renneson, J.4    Blanc, F.5    Pichavant, M.6
  • 99
    • 0033972422 scopus 로고    scopus 로고
    • Synergistic action of pro-inflammatory agents: cellular and molecular aspects
    • Paludan, S. R. (2000). Synergistic action of pro-inflammatory agents: cellular and molecular aspects. J. Leukoc. Biol. 67, 18-25.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 18-25
    • Paludan, S.R.1
  • 100
    • 2342458559 scopus 로고    scopus 로고
    • Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3
    • Pan, H., Hong, F., Radaeva, S., and Gao, B. (2004). Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3. Cell. Mol. Immunol. 1, 43-49.
    • (2004) Cell. Mol. Immunol. , vol.1 , pp. 43-49
    • Pan, H.1    Hong, F.2    Radaeva, S.3    Gao, B.4
  • 101
    • 0037076710 scopus 로고    scopus 로고
    • Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10
    • Parato, K. G., Kumar, A., Badley, A. D., Sanchez-Dardon, J. L., Chambers, K. A., Young, C. D., et al. (2002). Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10. AIDS 16, 1251-1256.
    • (2002) AIDS , vol.16 , pp. 1251-1256
    • Parato, K.G.1    Kumar, A.2    Badley, A.D.3    Sanchez-Dardon, J.L.4    Chambers, K.A.5    Young, C.D.6
  • 102
    • 84855644010 scopus 로고    scopus 로고
    • IL-15-induced IL-10 increases the cytolytic activity of human natural killer cells
    • Park, J. Y., Lee, S. H., Yoon, S. R., Park, Y. J., Jung, H., Kim, T. D., et al. (2001). IL-15-induced IL-10 increases the cytolytic activity of human natural killer cells. Mol. Cells 32, 265-272.
    • (2001) Mol. Cells , vol.32 , pp. 265-272
    • Park, J.Y.1    Lee, S.H.2    Yoon, S.R.3    Park, Y.J.4    Jung, H.5    Kim, T.D.6
  • 103
    • 79955776494 scopus 로고    scopus 로고
    • In vivo consequences of liver-specific interleukin-22 expression in mice: implications for human liver disease progression
    • Park, O., Wang, H., Weng, H., Feigenbaum, L., Li, H., Yin, S., et al. (2011). In vivo consequences of liver-specific interleukin-22 expression in mice: implications for human liver disease progression. Hepatology 54, 252-261.
    • (2011) Hepatology , vol.54 , pp. 252-261
    • Park, O.1    Wang, H.2    Weng, H.3    Feigenbaum, L.4    Li, H.5    Yin, S.6
  • 104
    • 83155172493 scopus 로고    scopus 로고
    • Inflamed gut mucosa: downstream of interleukin-10
    • Paul, G., Khare, V., and Gasche, C. (2012). Inflamed gut mucosa: downstream of interleukin-10. Eur. J. Clin. Invest. 42, 95-109.
    • (2012) Eur. J. Clin. Invest. , vol.42 , pp. 95-109
    • Paul, G.1    Khare, V.2    Gasche, C.3
  • 105
    • 67650474246 scopus 로고    scopus 로고
    • STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
    • Pickert, G., Neufert, C., Leppkes, M., Zheng, Y., Wittkopf, N., Warntjen, M., et al. (2009). STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med. 206, 1465-1472.
    • (2009) J. Exp. Med. , vol.206 , pp. 1465-1472
    • Pickert, G.1    Neufert, C.2    Leppkes, M.3    Zheng, Y.4    Wittkopf, N.5    Warntjen, M.6
  • 106
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon-mediated signalling
    • Platanias, L. C. (2005). Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5, 375-386.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 107
    • 77955423259 scopus 로고    scopus 로고
    • New lessons about old molecules: how type I interferons shape Th1/Th17-mediated autoimmunity in the CNS
    • Prinz, M., and Kalinke, U. (2010). New lessons about old molecules: how type I interferons shape Th1/Th17-mediated autoimmunity in the CNS. Trends Mol. Med. 16, 379-386.
    • (2010) Trends Mol. Med. , vol.16 , pp. 379-386
    • Prinz, M.1    Kalinke, U.2
  • 108
    • 33749355639 scopus 로고    scopus 로고
    • TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation
    • Qian, C., Jiang, X., An, H., Yu, Y., Guo, Z., Liu, S., et al. (2006). TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation. Blood 108, 2307-2315.
    • (2006) Blood , vol.108 , pp. 2307-2315
    • Qian, C.1    Jiang, X.2    An, H.3    Yu, Y.4    Guo, Z.5    Liu, S.6
  • 109
    • 2342462460 scopus 로고    scopus 로고
    • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
    • Radaeva, S., Sun, R., Pan, H. N., Hong, F., and Gao, B. (2004). Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology 39, 1332-1342.
    • (2004) Hepatology , vol.39 , pp. 1332-1342
    • Radaeva, S.1    Sun, R.2    Pan, H.N.3    Hong, F.4    Gao, B.5
  • 111
    • 0031740883 scopus 로고    scopus 로고
    • Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8
    • Reznikov, L. L., Puren, A. J., Fantuzzi, G., Mühl, H., Shapiro, L., Yoon, D. Y., et al. (1998). Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8. J. Interferon Cytokine Res. 18, 897-903.
    • (1998) J. Interferon Cytokine Res. , vol.18 , pp. 897-903
    • Reznikov, L.L.1    Puren, A.J.2    Fantuzzi, G.3    Mühl, H.4    Shapiro, L.5    Yoon, D.Y.6
  • 112
    • 79959700032 scopus 로고    scopus 로고
    • Research in practice: IL-22 and IL-20: significance for epithelial homeostasis and psoriasis pathogenesis
    • Sabat, R., and Wolk, K. (2011). Research in practice: IL-22 and IL-20: significance for epithelial homeostasis and psoriasis pathogenesis. J. Dtsch. Dermatol. Ges. 9, 518-523.
    • (2011) J. Dtsch. Dermatol. Ges. , vol.9 , pp. 518-523
    • Sabat, R.1    Wolk, K.2
  • 113
    • 0033997779 scopus 로고    scopus 로고
    • Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytes
    • Santin, A. D., Hermonat, P. L., Ravaggi, A., Bellone, S., Pecorelli, S., Roman, J. J., et al. (2000). Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytes. J. Virol. 74, 4729-4737.
    • (2000) J. Virol. , vol.74 , pp. 4729-4737
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3    Bellone, S.4    Pecorelli, S.5    Roman, J.J.6
  • 114
    • 0034662994 scopus 로고    scopus 로고
    • IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells
    • Sareneva, T., Julkunen, I., and Matikainen, S. (2000). IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells. J. Immunol. 165, 1933-1938.
    • (2000) J. Immunol. , vol.165 , pp. 1933-1938
    • Sareneva, T.1    Julkunen, I.2    Matikainen, S.3
  • 115
    • 57449118239 scopus 로고    scopus 로고
    • Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
    • Satoh-Takayama, N., Vosshenrich, C. A., Lesjean-Pottier, S., Sawa, S., Lochner, M., Rattis, F., et al. (2008). Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29, 958-970.
    • (2008) Immunity , vol.29 , pp. 958-970
    • Satoh-Takayama, N.1    Vosshenrich, C.A.2    Lesjean-Pottier, S.3    Sawa, S.4    Lochner, M.5    Rattis, F.6
  • 117
    • 84883736635 scopus 로고    scopus 로고
    • Application of interleukin-22 mediates protection in experimental acetaminophen-induced acute liver injury
    • (in press)
    • Scheiermann, P., Bachmann, M., Goren, I., Zwissler, B., Pfeilschifter, J., and Mühl, H. (2012). Application of interleukin-22 mediates protection in experimental acetaminophen-induced acute liver injury. Am. J. Pathol. (in press).
    • (2012) Am. J. Pathol.
    • Scheiermann, P.1    Bachmann, M.2    Goren, I.3    Zwissler, B.4    Pfeilschifter, J.5    Mühl, H.6
  • 118
    • 34547469463 scopus 로고    scopus 로고
    • Development of ulcerative colitis in a patient with multiple sclerosis following treatment with interferon beta 1a
    • Schott, E., Paul, F., Wuerfel, J. T., Zipp, F., Rudolph, B., Wiedenmann, B., et al. (2007). Development of ulcerative colitis in a patient with multiple sclerosis following treatment with interferon beta 1a. World J. Gastroenterol. 13, 3638-3640.
    • (2007) World J. Gastroenterol. , vol.13 , pp. 3638-3640
    • Schott, E.1    Paul, F.2    Wuerfel, J.T.3    Zipp, F.4    Rudolph, B.5    Wiedenmann, B.6
  • 119
    • 0036716702 scopus 로고    scopus 로고
    • Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease
    • Schreiber, S., Rosenstiel, P., Hampe, J., Nikolaus, S., Groessner, B., Schottelius, A., et al. (2002). Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease. Gut 51, 379-385.
    • (2002) Gut , vol.51 , pp. 379-385
    • Schreiber, S.1    Rosenstiel, P.2    Hampe, J.3    Nikolaus, S.4    Groessner, B.5    Schottelius, A.6
  • 120
    • 34248218104 scopus 로고    scopus 로고
    • Sensitization to TLR7 agonist in IFN-beta-preactivated dendritic cells
    • Severa, M., Remoli, M. E., Giacomini, E., Annibali, V., Gafa, V., Lande, R., et al. (2007). Sensitization to TLR7 agonist in IFN-beta-preactivated dendritic cells. J. Immunol. 178, 6208-6216.
    • (2007) J. Immunol. , vol.178 , pp. 6208-6216
    • Severa, M.1    Remoli, M.E.2    Giacomini, E.3    Annibali, V.4    Gafa, V.5    Lande, R.6
  • 121
    • 2442609662 scopus 로고    scopus 로고
    • IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis
    • Sharif, M. N., Tassiulas, I., Hu, Y., Mecklenbräuker, I., Tarakhovsky, A., and Ivashkiv, L. B. (2004). IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis. J. Immunol. 172, 6476-6481.
    • (2004) J. Immunol. , vol.172 , pp. 6476-6481
    • Sharif, M.N.1    Tassiulas, I.2    Hu, Y.3    Mecklenbräuker, I.4    Tarakhovsky, A.5    Ivashkiv, L.B.6
  • 122
    • 0032532305 scopus 로고    scopus 로고
    • Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma
    • Shibata, Y., Foster, L. A., Kurimoto, M., Okamura, H., Nakamura, R. M., Kawajiri, K., et al. (1998). Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma. J. Immunol. 161, 4283-4288.
    • (1998) J. Immunol. , vol.161 , pp. 4283-4288
    • Shibata, Y.1    Foster, L.A.2    Kurimoto, M.3    Okamura, H.4    Nakamura, R.M.5    Kawajiri, K.6
  • 123
    • 79955030498 scopus 로고    scopus 로고
    • Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
    • Sonnenberg, G. F., Fouser, L. A., and Artis, D. (2011). Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat. Immunol. 12, 383-390.
    • (2011) Nat. Immunol. , vol.12 , pp. 383-390
    • Sonnenberg, G.F.1    Fouser, L.A.2    Artis, D.3
  • 124
    • 84861989207 scopus 로고    scopus 로고
    • Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
    • Sonnenberg, G. F., Monticelli, L. A., Alenghat, T., Fung, T. C., Hutnick, N. A., Kunisawa, J., et al. (2012). Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 336, 1321-1325.
    • (2012) Science , vol.336 , pp. 1321-1325
    • Sonnenberg, G.F.1    Monticelli, L.A.2    Alenghat, T.3    Fung, T.C.4    Hutnick, N.A.5    Kunisawa, J.6
  • 125
    • 84862620612 scopus 로고    scopus 로고
    • Natural killer (NK) cells in antibacterial innate immunity: angels or devils? Mol
    • Souza-Fonseca-Guimaraes, F., Adib-Conquy, M., and Cavaillon, J. M. (2012). Natural killer (NK) cells in antibacterial innate immunity: angels or devils? Mol. Med. 18, 270-285.
    • (2012) Med. , vol.18 , pp. 270-285
    • Souza-Fonseca-Guimaraes, F.1    Adib-Conquy, M.2    Cavaillon, J.M.3
  • 126
    • 14544304528 scopus 로고    scopus 로고
    • Acute ulcerative colitis during successful interferon/ribavirin treatment for chronic hepatitis
    • Sprenger, R., Sagmeister, M., and Offner, F. (2005). Acute ulcerative colitis during successful interferon/ribavirin treatment for chronic hepatitis. Gut 54, 438-439.
    • (2005) Gut , vol.54 , pp. 438-439
    • Sprenger, R.1    Sagmeister, M.2    Offner, F.3
  • 127
    • 38849141814 scopus 로고    scopus 로고
    • IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
    • Sugimoto, K., Ogawa, A., Mizoguchi, E., Shimomura, Y., Andoh, A., Bhan, A. K., et al. (2008). IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118, 534-544.
    • (2008) J. Clin. Invest. , vol.118 , pp. 534-544
    • Sugimoto, K.1    Ogawa, A.2    Mizoguchi, E.3    Shimomura, Y.4    Andoh, A.5    Bhan, A.K.6
  • 128
    • 34250203538 scopus 로고    scopus 로고
    • Type I IFN contributes to NK cell homeostasis, activation, and antitumor function
    • Swann, J. B., Hayakawa, Y., Zerafa, N., Sheehan, K. C., Scott, B., Schreiber, R. D., et al. (2007). Type I IFN contributes to NK cell homeostasis, activation, and antitumor function. J. Immunol. 178, 7540-7549.
    • (2007) J. Immunol. , vol.178 , pp. 7540-7549
    • Swann, J.B.1    Hayakawa, Y.2    Zerafa, N.3    Sheehan, K.C.4    Scott, B.5    Schreiber, R.D.6
  • 129
    • 0034733672 scopus 로고    scopus 로고
    • Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains
    • Takaoka, A., Mitani, Y., Suemori, H., Sato, M., Yokochi, T., Noguchi, S., et al. (2000). Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains. Science 288, 2357-2360.
    • (2000) Science , vol.288 , pp. 2357-2360
    • Takaoka, A.1    Mitani, Y.2    Suemori, H.3    Sato, M.4    Yokochi, T.5    Noguchi, S.6
  • 130
    • 33646377870 scopus 로고    scopus 로고
    • Interferon signalling network in innate defence
    • Takaoka, A., and Yanai, H. (2006). Interferon signalling network in innate defence. Cell. Microbiol. 8, 907-922.
    • (2006) Cell. Microbiol. , vol.8 , pp. 907-922
    • Takaoka, A.1    Yanai, H.2
  • 131
    • 0035344461 scopus 로고    scopus 로고
    • A weak signal for strong responses: interferon-alpha/beta revisited
    • Taniguchi, T., and Takaoka, A. (2001). A weak signal for strong responses: interferon-alpha/beta revisited. Nat. Rev. Mol. Cell Biol. 2, 378-386.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 378-386
    • Taniguchi, T.1    Takaoka, A.2
  • 132
    • 0037407587 scopus 로고    scopus 로고
    • IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis
    • Teige, I., Treschow, A., Teige, A., Mattsson, R., Navikas, V., Leanderson, T., et al. (2003). IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis. J. Immunol. 170, 4776-4784.
    • (2003) J. Immunol. , vol.170 , pp. 4776-4784
    • Teige, I.1    Treschow, A.2    Teige, A.3    Mattsson, R.4    Navikas, V.5    Leanderson, T.6
  • 133
    • 0036153395 scopus 로고    scopus 로고
    • Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma
    • Tilg, H., van Montfrans, C., van den Ende, A., Kaser, A., van Deventer, S. J., Schreiber, S., et al. (2002). Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma. Gut 50, 191-195.
    • (2002) Gut , vol.50 , pp. 191-195
    • Tilg, H.1    van Montfrans, C.2    van den Ende, A.3    Kaser, A.4    van Deventer, S.J.5    Schreiber, S.6
  • 134
    • 84862777960 scopus 로고    scopus 로고
    • IFN-α enhances IL-22 receptor expression in keratinocytes: a possible role in the development of psoriasis
    • Tohyama, M., Yang, L., Hanakawa, Y., Dai, X., Shirakata, Y., and Sayama, K. (2012). IFN-α enhances IL-22 receptor expression in keratinocytes: a possible role in the development of psoriasis. J. Invest. Dermatol. 132, 1933-1935.
    • (2012) J. Invest. Dermatol. , vol.132 , pp. 1933-1935
    • Tohyama, M.1    Yang, L.2    Hanakawa, Y.3    Dai, X.4    Shirakata, Y.5    Sayama, K.6
  • 135
    • 29144459002 scopus 로고    scopus 로고
    • Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-beta-deficient mice
    • Treschow, A. P., Teige, I., Nandakumar, K. S., Holmdahl, R., and Issazadeh-Navikas, S. (2005). Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-beta-deficient mice. Arthritis Rheum. 52, 3739-3748.
    • (2005) Arthritis Rheum. , vol.52 , pp. 3739-3748
    • Treschow, A.P.1    Teige, I.2    Nandakumar, K.S.3    Holmdahl, R.4    Issazadeh-Navikas, S.5
  • 136
    • 77957745555 scopus 로고    scopus 로고
    • Type I interferon: friend or foe? J
    • Trinchieri, G. (2010). Type I interferon: friend or foe? J. Exp. Med. 207, 2053-2063.
    • (2010) Exp. Med. , vol.207 , pp. 2053-2063
    • Trinchieri, G.1
  • 137
    • 44849128066 scopus 로고    scopus 로고
    • Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients
    • doi:10.1371/journal.pone.0001927
    • van Baarsen, L. G., Vosslamber, S., Tijssen, M., Baggen, J. M., van der Voort, L. F., Killestein, J., et al. (2008). Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients. PLoS ONE 3:e1927. doi:10.1371/journal.pone.0001927
    • (2008) PLoS ONE , vol.3
    • van Baarsen, L.G.1    Vosslamber, S.2    Tijssen, M.3    Baggen, J.M.4    van der Voort, L.F.5    Killestein, J.6
  • 140
    • 27944510972 scopus 로고    scopus 로고
    • Expression of interferon beta in synovial tissue from patients with rheumatoid arthritis: comparison with patients with osteoarthritis and reactive arthritis
    • van Holten, J., Smeets, T. J., Blankert, P., and Tak, P. P. (2005). Expression of interferon beta in synovial tissue from patients with rheumatoid arthritis: comparison with patients with osteoarthritis and reactive arthritis. Ann. Rheum. Dis. 64, 1780-1782.
    • (2005) Ann. Rheum. Dis. , vol.64 , pp. 1780-1782
    • van Holten, J.1    Smeets, T.J.2    Blankert, P.3    Tak, P.P.4
  • 141
    • 0029959940 scopus 로고    scopus 로고
    • Interleukin-10 inhibition of the progression of established collagen-induced arthritis
    • Walmsley, M., Katsikis, P. D., Abney, E., Parry, S., Williams, R. O., Maini, R. N., et al. (1996). Interleukin-10 inhibition of the progression of established collagen-induced arthritis. Arthritis Rheum. 39, 495-503.
    • (1996) Arthritis Rheum. , vol.39 , pp. 495-503
    • Walmsley, M.1    Katsikis, P.D.2    Abney, E.3    Parry, S.4    Williams, R.O.5    Maini, R.N.6
  • 142
    • 79955756575 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target
    • Wang, H., Lafdil, F., Kong, X., and Gao, B. (2011). Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target. Int. J. Biol. Sci. 7, 536-550.
    • (2011) Int. J. Biol. Sci. , vol.7 , pp. 536-550
    • Wang, H.1    Lafdil, F.2    Kong, X.3    Gao, B.4
  • 143
    • 0037771321 scopus 로고    scopus 로고
    • Inhibition of neutrophil apoptosis by type 1 IFN depends on cross-talk between phosphoinositol 3-kinase, protein kinase C-delta, and NF-kappa B signaling pathways
    • Wang, K., Scheel-Toellner, D., Wong, S. H., Craddock, R., Caamano, J., Akbar, A. N., et al. (2003). Inhibition of neutrophil apoptosis by type 1 IFN depends on cross-talk between phosphoinositol 3-kinase, protein kinase C-delta, and NF-kappa B signaling pathways. J. Immunol. 171, 1035-1041.
    • (2003) J. Immunol. , vol.171 , pp. 1035-1041
    • Wang, K.1    Scheel-Toellner, D.2    Wong, S.H.3    Craddock, R.4    Caamano, J.5    Akbar, A.N.6
  • 144
    • 84865483236 scopus 로고    scopus 로고
    • IL-22 signaling contributes to west nile encephalitis pathogenesis
    • doi:10.1371/journal.pone.0044153
    • Wang, P., Bai, F., Zenewicz, L. A., Dai, J., Gate, D., Cheng, G., et al. (2012). IL-22 signaling contributes to west nile encephalitis pathogenesis. PLoS ONE 7:e44153. doi:10.1371/journal.pone.0044153
    • (2012) PLoS ONE , vol.7
    • Wang, P.1    Bai, F.2    Zenewicz, L.A.3    Dai, J.4    Gate, D.5    Cheng, G.6
  • 145
    • 33750350271 scopus 로고    scopus 로고
    • A case of exacerbation of ulcerative colitis induced by combination therapy with PEG-interferon alpha-2b and ribavirin
    • Watanabe, T., Inoue, M., Harada, K., Homma, N., Uchida, M., Ogata, N., et al. (2006). A case of exacerbation of ulcerative colitis induced by combination therapy with PEG-interferon alpha-2b and ribavirin. Gut 55, 1682-1683.
    • (2006) Gut , vol.55 , pp. 1682-1683
    • Watanabe, T.1    Inoue, M.2    Harada, K.3    Homma, N.4    Uchida, M.5    Ogata, N.6
  • 146
    • 0030046876 scopus 로고    scopus 로고
    • Cutaneous ulcerations and pustular psoriasis flare caused by recombinant interferon beta injections in patients with multiple sclerosis
    • Webster, G. F., Knobler, R. L., Lublin, F. D., Kramer, E. M., and Hochman, L. R. (1996). Cutaneous ulcerations and pustular psoriasis flare caused by recombinant interferon beta injections in patients with multiple sclerosis. J. Am. Acad. Dermatol. 34, 365-367.
    • (1996) J. Am. Acad. Dermatol. , vol.34 , pp. 365-367
    • Webster, G.F.1    Knobler, R.L.2    Lublin, F.D.3    Kramer, E.M.4    Hochman, L.R.5
  • 147
    • 25644435503 scopus 로고    scopus 로고
    • On the role of sIL-2R measurements in rheumatoid arthritis and cancers
    • Witkowska, A. M. (2005). On the role of sIL-2R measurements in rheumatoid arthritis and cancers. Mediators Inflamm. 2005, 121-130.
    • (2005) Mediators Inflamm. , vol.2005 , pp. 121-130
    • Witkowska, A.M.1
  • 148
    • 84863006274 scopus 로고    scopus 로고
    • IL-27 regulates IL-18 binding protein in skin resident cells
    • doi:10.1371/journal.pone.0038751
    • Wittmann, M., Doble, R., Bachmann, M., Pfeilschifter, J., Werfel, T., and Mühl, H. (2012). IL-27 regulates IL-18 binding protein in skin resident cells. PLoS ONE 7:e38751. doi:10.1371/journal.pone.0038751
    • (2012) PLoS ONE , vol.7
    • Wittmann, M.1    Doble, R.2    Bachmann, M.3    Pfeilschifter, J.4    Werfel, T.5    Mühl, H.6
  • 149
    • 67349195975 scopus 로고    scopus 로고
    • IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not
    • Wolk, K., Haugen, H. S., Xu, W., Witte, E., Waggie, K., Anderson, M., et al. (2009). IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not. J. Mol. Med. (Berl.) 87, 523-536.
    • (2009) J. Mol. Med. (Berl.) , vol.87 , pp. 523-536
    • Wolk, K.1    Haugen, H.S.2    Xu, W.3    Witte, E.4    Waggie, K.5    Anderson, M.6
  • 152
    • 0034613201 scopus 로고    scopus 로고
    • Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
    • Xie, M. H., Aggarwal, S., Ho, W. H., Foster, J., Zhang, Z., Stinson, J., et al. (2000). Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275, 31335-31339.
    • (2000) J. Biol. Chem. , vol.275 , pp. 31335-31339
    • Xie, M.H.1    Aggarwal, S.2    Ho, W.H.3    Foster, J.4    Zhang, Z.5    Stinson, J.6
  • 153
    • 79960769980 scopus 로고    scopus 로고
    • Interleukin-22 protects against acute alcohol-induced hepatotoxicity in mice
    • Xing, W. W., Zou, M. J., Liu, S., Xu, T., Wang, J. X., and Xu, D. G. (2011). Interleukin-22 protects against acute alcohol-induced hepatotoxicity in mice. Biosci. Biotechnol. Biochem. 75, 1290-1294.
    • (2011) Biosci. Biotechnol. Biochem. , vol.75 , pp. 1290-1294
    • Xing, W.W.1    Zou, M.J.2    Liu, S.3    Xu, T.4    Wang, J.X.5    Xu, D.G.6
  • 154
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: a leading role for STAT3
    • Yu, H., Pardoll, D., and Jove, R. (2009). STATs in cancer inflammation and immunity: a leading role for STAT3. Nat. Rev. Cancer 9, 798-809.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 155
    • 35348983341 scopus 로고    scopus 로고
    • Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation
    • Zenewicz, L. A., Yancopoulos, G. D., Valenzuela, D. M., Murphy, A. J., Karow, M., and Flavell, R. A. (2007). Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity 27, 647-659.
    • (2007) Immunity , vol.27 , pp. 647-659
    • Zenewicz, L.A.1    Yancopoulos, G.D.2    Valenzuela, D.M.3    Murphy, A.J.4    Karow, M.5    Flavell, R.A.6
  • 157
    • 55149102403 scopus 로고    scopus 로고
    • Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense
    • Zhang, S. Y., Boisson-Dupuis, S., Chapgier, A., Yang, K., Bustamante, J., Puel, A., et al. (2008a). Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol. Rev. 226, 29-40.
    • (2008) Immunol. Rev. , vol.226 , pp. 29-40
    • Zhang, S.Y.1    Boisson-Dupuis, S.2    Chapgier, A.3    Yang, K.4    Bustamante, J.5    Puel, A.6
  • 158
    • 58149183235 scopus 로고    scopus 로고
    • Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts
    • Zhang, W., Chen, Y., Wei, H., Zheng, C., Sun, R., Zhang, J., et al. (2008b). Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts. Clin. Cancer Res. 14, 6432-6439.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6432-6439
    • Zhang, W.1    Chen, Y.2    Wei, H.3    Zheng, C.4    Sun, R.5    Zhang, J.6
  • 159
    • 80054847781 scopus 로고    scopus 로고
    • A proinflammatory role for interleukin-22 in the immune response to hepatitis B virus
    • Zhang, Y., Cobleigh, M. A., Lian, J. Q., Huang, C. X., Booth, C. J., Bai, X. F., et al. (2011). A proinflammatory role for interleukin-22 in the immune response to hepatitis B virus. Gastroenterology 141, 1897-1906.
    • (2011) Gastroenterology , vol.141 , pp. 1897-1906
    • Zhang, Y.1    Cobleigh, M.A.2    Lian, J.Q.3    Huang, C.X.4    Booth, C.J.5    Bai, X.F.6
  • 160
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng, Y., Valdez, P. A., Danilenko, D. M., Hu, Y., Sa, S. M., Gong, Q., et al. (2008). Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat. Med. 14, 282-289.
    • (2008) Nat. Med. , vol.14 , pp. 282-289
    • Zheng, Y.1    Valdez, P.A.2    Danilenko, D.M.3    Hu, Y.4    Sa, S.M.5    Gong, Q.6
  • 161
    • 45749110171 scopus 로고    scopus 로고
    • A critical role for type I IFN-dependent NK cell activation in innate immune elimination of adenoviral vectors in vivo
    • Zhu, J., Huang, X., and Yang, Y. (2008). A critical role for type I IFN-dependent NK cell activation in innate immune elimination of adenoviral vectors in vivo. Mol. Ther. 16, 1300-1307.
    • (2008) Mol. Ther. , vol.16 , pp. 1300-1307
    • Zhu, J.1    Huang, X.2    Yang, Y.3
  • 162
    • 34447521412 scopus 로고    scopus 로고
    • The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells
    • Ziesché, E., Bachmann, M., Kleinert, H., Pfeilschifter, J., and Mühl, H. (2007). The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. J. Biol. Chem. 282, 16006-16015.
    • (2007) J. Biol. Chem. , vol.282 , pp. 16006-16015
    • Ziesché, E.1    Bachmann, M.2    Kleinert, H.3    Pfeilschifter, J.4    Mühl, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.