Cross talk of the interferon-α/β signalling complex with gp130 for effective interleukin-6 signalling

Genes to Cells

Volumn 6, Issue 7, 2001, Pages 631-640

  Mitani, Y ^a   Takaoka, A ^a   Kim, S H ^a   Kato, Y ^a   Yokochi, T ^a   Tanaka, N ^a   Taniguchi, T ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CYTOKINE; CYTOKINE RECEPTOR; DIMER; GAMMA INTERFERON; GLYCOPROTEIN GP 130; INTERFERON ALPHA RECEPTOR SUBUNIT 1; INTERFERON BETA RECEPTOR SUBUNIT 1; INTERFERON RECEPTOR; INTERLEUKIN 6; RECEPTOR SUBUNIT; STAT1 PROTEIN; STAT3 PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; MODULATION; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; DIMERIZATION; EMBRYO; FIBROBLASTS; GENE EXPRESSION REGULATION; INTERFERON TYPE I; INTERFERON-ALPHA; INTERFERON-BETA; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; NEURAL CELL ADHESION MOLECULES; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; RECEPTOR CROSS-TALK; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0034884781     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.2001.00448.x     Document Type: Article

References (45)

1. Interferon regulatory factor 1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: Role in growth inhibition
2. Targeted disruption of the IL-6 related genes: gp130 and NF-IL-6
3. The caveolae membrane system
4. Functions of lipid rafts in biological membranes
5. Transcriptional regulation of the junB promoter: Analysis of STAT-mediated signal transduction
6. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
7. Signaling takes shape in the immune system
8. The molecular cell biology of interferon-γ and its receptor
9. Signal transduction through cytokine receptors
10. Interleukin-6
11. Absence of antiviral activity in recombinant B cell stimulatory factor 2 (BSF-2)
12. Jaks and Stats in signaling by the cytokine receptor superfamily
13. IL-6-inducible complexes on an IL-6 response element of the junB promoter contain Stat3 and 36 kDa CRE-like site binding protein(s)
14. Pleiotropic defects of IL-6-deficient mice including early hematopoiesis, T and B cell function, and acute phase responses
15. Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598
16. Membrane rafts and signaling by the multichain immune recognition receptors
17. Functional sub-domains of STAT2 required for preassociation with the a interferon receptor and for signaling
18. Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane
19. Cytokine receptors and signal transduction
20. Functional role of type I and type II interferons in antiviral defense
21. Type 1 IFNs and regulation of TH1 responses: Enigmas both resolved and emerge
22. Lymphocyte responses and cytokines
23. STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor
24. Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells
25. Antiviral action of tumor necrosis factor in human fibroblasts is not mediated by B cell stimulatory factor 2/IFN-β2, and is inhibited by specific antibodies to IFN-β
26. A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
27. IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: Demonstration of a novel role for c-myc
28. Functional rafts in cell membranes
29. A detergent-free method for purifying caveolae membrane from tissue culture cells
30. The acute phase protein response during parasitic infection
31. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
32. Distinct mechanisms of STAT phosphorylation via the interferon-α/β receptor. Selective inhibition of STAT3 and STAT5 by piceatannol
33. Gp130 and the interleukin-6 family of cytokines
34. Cross talk between interferon-γ and -α/β signaling components in caveolar membrane domains
35. Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-γ, but not IFN-α, signaling
36. Cytokine signaling through nonreceptor protein tyrosine kinases
37. Transcriptional activation: A complex puzzle with few easy pieces
38. Activation of IFN-β element by IRF-1 requires a posttranslational event in addition to IRF-1 synthesis
39. The interleukin-6-activated acute-phase response factor is anti-genically and functionally related to members of the signal transducer and activator of transcription (STAT) family
40. Interaction of the erythropoietin and stem-cell-factor receptors
41. Membrane compartmentation is required for efficient T cell activation
42. Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor
43. Requirement of serine phosphorylation for formation of STAT-promoter complexes