Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

Arthritis and Rheumatism

Volumn 60, Issue 2, 2009, Pages 390-395

  Geboes, Lies ^a,c   Dumoutier, Laure ^b   Kelchtermans, Hilde ^a   Schurgers, Evelien ^a   Mitera, Tania ^a   Renauld, Jean Christophe ^b   Matthys, Patrick ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; INTERLEUKIN 22; INTERLEUKIN 22 RECEPTOR 1; INTERLEUKIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; HUMORAL IMMUNITY; LYMPHOID TISSUE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PANNUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SPLEEN CELL;

ACID PHOSPHATASE; ANIMALS; ARTHRITIS, EXPERIMENTAL; CELL LINE; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN G; INTERLEUKINS; ISOENZYMES; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOCLASTS; RECEPTORS, INTERLEUKIN; RECOMBINANT PROTEINS; RNA, MESSENGER; SPLEEN;

EID: 59649086053     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24220     Document Type: Article

References (15)

1. Renauld JC. Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators. Nat Rev Immunol 2003;3:667-76.
2. Liang SC, Tan XY, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, Collins M, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006;203:2271-9.
3. Wolk K, Sabat R. Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells. Cytokine Growth Factor Rev 2006;17:367-80.
4. Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, et al. Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rβ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J Biol Chem 2001;276:2725-32.
5. Ikeuchi H, Kuroiwa T, Hiramatsu N, Kaneko Y, Hiromura K, Ueki K, et al. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum 2005;52:1037-46.
6. Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Q, et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 2008;14:282-9.
7. Ma HL, Liang S, Li J, Napierata L, Brown T, Benoit S, et al. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest 2008;118:597-607.
8. Kreymborg K, Etzensperger R, Dumoutier L, Haak S, Rebollo A, Buch T, et al. IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol 2007;179:8098-104.
9. Campbell IK, Hamilton JA, Wicks IP. Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis. Eur J Immunol 2000;30:1568-75.
10. Inglis JJ, Simelyte E, McCann FE, Criado G, Williams RO. Protocol for the induction of arthritis in C57BL/6 mice. Nat Protoc 2008;3:612-8.
11. De Klerck B, Geboes L, Hatse S, Kelchtermans H, Meyvis Y, Vermeire K, et al. Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis. Arthritis Res Ther 2005;7:R1208-20.
12. Dumoutier L, Louahed J, Renauld JC. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J Immunol 2000;164:1814-9.
13. Geboes L, De Klerck B, Van Balen M, Kelchtermans H, Mitera T, Boon L, et al. Freund's complete adjuvant induces arthritis in mice lacking a functional interferon-γ receptor by triggering tumor necrosis factor α-driven osteoclastogenesis. Arthritis Rheum 2007;56:2595-607.
14. Modderman WE, Tuinenburg-Bol Raap AC, Nijweide PJ. Tartrate-resistant acid phosphatase is not an exclusive marker for mouse osteoclasts in cell culture. Bone 1991;12:81-7.
15. Martin RM, Brady JL, Lew AM. The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice. J Immunol Methods 1998;212:187-92.