Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis

Experimental Lung Research

Volumn 28, Issue 1, 2002, Pages 55-68

  John, M ^a   Oltmanns, U ^a   Fietze, I ^a   Witt, C ^a   Jung, K ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

IL 10; MMP 2; MMP 9; Pulmonary inflammatory diseases

Indexed keywords

CATHEPSIN B; CATHEPSIN L; GELATINASE A; GELATINASE B; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FLUOROMETRY; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG LAVAGE; LUNG SARCOIDOSIS; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; ZYMOGRAPHY;

ADULT; AGED; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; CATHEPSIN B; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; HUMANS; INTERLEUKIN-10; MACROPHAGES, ALVEOLAR; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; PNEUMONIA, BACTERIAL; PULMONARY FIBROSIS; SARCOIDOSIS, PULMONARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036138869     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.1080/019021402753355535     Document Type: Article

References (35)

1. Role of matrix metalloproteinases in models of macrophage-dependent acute lung injury. Evidence for alveolar macrophage as source of proteinases
2. Characterization of matrix metalloproteinases produced by rat alveolar macrophages
3. Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma
4. Cysteine proteinases and their endogenous inhibitors: Target proteins for prognosis, diagnosis and therapy in cancer
5. Prognostic impact of cathepsin B and matrix metalloproteinase-9 in pulmonary adenocarcinomas by immunohistochemical study
6. Cathepsins B, H, L and cysteine protease inhibitors in malignant prostate cell lines, primary cultured prostatic cells and prostatic tissue
7. Proteinases and proteinase inhibitors during the development of pulmonary fibrosis in rat
8. Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: Effects of steroid and immunosuppressive treatment
9. Increased expression of proinflammatory chemokines in bronchoalveolar lavage cells of patients with progressing idiopathic pulmonary fibrosis, and sarcoidosis
10. Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases
11. Interstitial lung diseases of unknown cause
12. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee
13. Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1α, granulocyte-macrophage colony-stimulating factor, and interferon-γ release from alveolar macrophages in asthma
14. Inhibition of macrophage inflammatory protein-1α by interleukin-10: Differential sensitivities in human blood monocytes and alveolar macrophages
15. Quantification of matrix metalloproteinases in tissue samples
16. Cathepsin B, cathepsin H, and cathepsin L
17. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD
18. Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema
19. Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis
20. Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury
21. Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury
22. Contribution of 92 kDa gelatinase/type IV collagenase in bronchial inflammation during status asthmaticus
23. Subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation
24. Collagenase and gelatinase activities in bronchoalveolar lavage fluids during bleomycin-induced lung injury
25. Cytokine mRNA gene expression in active and nonactive pulmonary sarcoidosis
26. Interleukin-10 secretion by alveolar macrophages and monocytes in sarcoidosis
27. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An auto-regulatory role of IL-10 produced by monocytes
28. IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells
29. Two types of mouse helper T cells. IV. Th 2 clones secrete a factor that inhibits cytokine production by Th 1 clones
30. Direct effects of IL-10 on subsets of human CD4+ T cell clones and resting T cells
31. IL-10 inhibition of human prostate PC-3 ML cell metastases in SCID mice: IL-10 stimulation of TIMP-1 and inhibition of MMP-2/MMP-9 expression
32. Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion
33. IL-10 is an autocrine inhibitor of human placental cytotrophoblast MMP-9 production and invasion
34. Expression of matrix metalloproteinases in human glioma cell lines in the presence of IL-10
35. Comparative effects of betamethasone, cyclosporin and nedocromil sodium in acute pulmonary inflammation and metalloproteinase activities in bronchoalveolar lavage fluid from mice exposed to lipopolysaccharide