Antigen-independent IFN-γ production by human naïve CD4+ T cells activated by IL-12 plus IL-18

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Munk, Rachel B ^a   Sugiyama, Katsuki ^a   Ghosh, Paritosh ^a   Sasaki, Carl Y ^a   Rezanka, Louis ^a   Banerjee, Kasturi ^a   Takahashi, Hidenori ^a   Sen, Ranjan ^a   Longo, Dan L ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CD45RA ANTIGEN; CD45RO ANTIGEN; GAMMA INTERFERON; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 18; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; RAPAMYCIN; STAT4 PROTEIN; TRANSCRIPTION FACTOR REL; DIFFERENTIATION ANTIGEN; GADD45B PROTEIN, HUMAN; GADD45G PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; MTOR PROTEIN, HUMAN; PYRIDINE DERIVATIVE; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MALE; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; POLYMERASE CHAIN REACTION;

ANIMALS; ANTIGENS, DIFFERENTIATION; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; HUMANS; IMIDAZOLES; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-18; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PYRIDINES; SIROLIMUS; STAT4 TRANSCRIPTION FACTOR; TOR SERINE-THREONINE KINASES;

EID: 79955897796     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018553     Document Type: Article

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