Mouse models of BRCA1 and their application to breast cancer research

Cancer and Metastasis Reviews

Volumn 32, Issue 1-2, 2013, Pages 25-37

  Dine, Jennifer ^a   Deng, Chu Xia ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

BRCA1; Breast cancer; Disease mechanism; Modeling; Therapy

Indexed keywords

AG 14361; BARDOXOLONE METHYL; BRCA1 PROTEIN; CARBOPLATIN; CISPLATIN; DOCETAXEL; DOXORUBICIN; ESTROGEN RECEPTOR; GENISTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OLAPARIB; RESVERATROL; TOPOTECAN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GRADING; CANCER PREVENTION; CANCER RESEARCH; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DRUG EFFICACY; EXON; FEMALE; GENE DISRUPTION; GENE FREQUENCY; GENE MUTATION; GENETIC PREDISPOSITION; HOMOLOGOUS RECOMBINATION; LOSS OF FUNCTION MUTATION; MISSENSE MUTATION; MOUSE; NONHUMAN; ONCOGENE; OVARIECTOMY; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ANIMALS; BREAST NEOPLASMS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, NEOPLASM; FEMALE; GENES, BRCA1; GERM-LINE MUTATION; HUMANS; MICE; ORGAN SPECIFICITY; PHENOTYPE; RESEARCH; SEX FACTORS;

EID: 84878115409     PISSN: 01677659     EISSN: 15737233     Source Type: Journal    
DOI: 10.1007/s10555-012-9403-7     Document Type: Article

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