The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 19, 2008, Pages 7040-7045

  Shakya, Reena ^a   Szabolcs, Matthias ^a   McCarthy, Ellen ^a   Ospina, Elson ^a   Basso, Katia ^a   Nandula, Subhadra ^a   Murty, Vundavalli ^a   Baer, Richard ^a   Ludwig, Thomas ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

Basal like breast cancer; Mammary carcinogenesis

Indexed keywords

BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA1 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HETERODIMER; PROGESTERONE RECEPTOR; PROTEIN P53; BARD1 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER INHIBITION; CONTROLLED STUDY; FEMALE; GENE INACTIVATION; GENE MUTATION; HISTOPATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; ANTIBODY SPECIFICITY; CHROMOSOMAL INSTABILITY; DIMERIZATION; EXPERIMENTAL NEOPLASM; GENE TARGETING; GENETICS; IMMUNOHISTOCHEMISTRY; KARYOTYPING; METABOLISM; MUTATION; PATHOLOGY; PHENOTYPE; SURVIVAL;

ANIMALIA; MUS;

ANIMALS; BRCA1 PROTEIN; CHROMOSOMAL INSTABILITY; DIMERIZATION; FEMALE; GENE TARGETING; IMMUNOHISTOCHEMISTRY; KARYOTYPING; MAMMARY NEOPLASMS, ANIMAL; MICE; MUTATION; ORGAN SPECIFICITY; PHENOTYPE; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 44349095084     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0711032105     Document Type: Article

References (39)

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