Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist

Science

Volumn 314, Issue 5804, 2006, Pages 1467-1470

  Poole, Aleksandra Jovanovic ^a,b   Li, Ying ^a,b   Kim, Yoon ^a,b   Lin, Suh Chin J ^a,b   Lee, Wen Hwa ^a   Lee, Eva Y H P ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; PROTEINS; TUMORS;

ANTIPROGESTERONE TREATMENT; EPITHELIAL CELLS; PROGESTERONE ANTAGONIST MIFEPRISTONE;

HORMONES;

ANTIGESTAGEN; ESTROGEN RECEPTOR; MIFEPRISTONE; PROGESTERONE RECEPTOR; PROTEASOME;

BIOASSAY; CANCER; DISEASE TREATMENT; HORMONE; RODENT; TUMOR; WOMENS HEALTH;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CANCER INHIBITION; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DEGRADATION; GENE MUTATION; GENE OVEREXPRESSION; HORMONE SENSITIVITY; MOUSE; MUTANT; NONHUMAN; NULLIPARA; ONCOGENE; OVARY CANCER; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; TISSUE SPECIFICITY; TREATMENT OUTCOME; TUMOR SUPPRESSOR GENE; WILD TYPE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; EPITHELIAL CELLS; ESTRADIOL; ESTROUS CYCLE; FEMALE; GENES, BRCA1; GENES, P53; HORMONE ANTAGONISTS; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MICE; MIFEPRISTONE; MUTATION; PHOSPHORYLATION; PROGESTERONE; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RNA, SMALL INTERFERING; UBIQUITIN;

EID: 33845315093     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1130471     Document Type: Article

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