메뉴 건너뛰기




Volumn 27, Issue 3, 2013, Pages 155-164

Regulating the regulators in cancer-immunosuppression in multiple myeloma (MM)

Author keywords

Cancer induced immune suppression; Immunotherapy; Myeloma; Regulatory T cells

Indexed keywords

CANCER VACCINE; DENDRITIC CELL VACCINE; ELOTUZUMAB; FLUDARABINE; INTERLEUKIN 2; SUNITINIB; THALIDOMIDE;

EID: 84877146756     PISSN: 0268960X     EISSN: 15321681     Source Type: Journal    
DOI: 10.1016/j.blre.2013.04.004     Document Type: Article
Times cited : (30)

References (185)
  • 1
    • 77950418217 scopus 로고    scopus 로고
    • CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus
    • [Research Support, Non-U.S. Gov't]
    • Krueger A., Willenzon S., Lyszkiewicz M., Kremmer E., Forster R. CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus. Blood Mar 11 2010, 115(10):1906-1912. [Research Support, Non-U.S. Gov't].
    • (2010) Blood , vol.115 , Issue.10 , pp. 1906-1912
    • Krueger, A.1    Willenzon, S.2    Lyszkiewicz, M.3    Kremmer, E.4    Forster, R.5
  • 2
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey D.I., Kennedy J., Suda T., Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol May 15 1993, 150(10):4244-4252.
    • (1993) J Immunol , vol.150 , Issue.10 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 3
    • 77954901331 scopus 로고    scopus 로고
    • Decision checkpoints in the thymus
    • [Research Support, N.I.H., Intramural Review]
    • Carpenter A.C., Bosselut R. Decision checkpoints in the thymus. Nat Immunol Aug 2010, 11(8):666-673. [Research Support, N.I.H., Intramural Review].
    • (2010) Nat Immunol , vol.11 , Issue.8 , pp. 666-673
    • Carpenter, A.C.1    Bosselut, R.2
  • 4
    • 22144487402 scopus 로고    scopus 로고
    • Notch signaling controls the generation and differentiation of early T lineage progenitors
    • [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Sambandam A., Maillard I., Zediak V.P., Xu L., Gerstein R.M., Aster J.C., et al. Notch signaling controls the generation and differentiation of early T lineage progenitors. Nat Immunol Jul 2005, 6(7):663-670. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (2005) Nat Immunol , vol.6 , Issue.7 , pp. 663-670
    • Sambandam, A.1    Maillard, I.2    Zediak, V.P.3    Xu, L.4    Gerstein, R.M.5    Aster, J.C.6
  • 5
    • 42049087865 scopus 로고    scopus 로고
    • The earliest thymic progenitors for T cells possess myeloid lineage potential
    • [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
    • Bell J.J., Bhandoola A. The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature Apr 10 2008, 452(7188):764-767. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't].
    • (2008) Nature , vol.452 , Issue.7188 , pp. 764-767
    • Bell, J.J.1    Bhandoola, A.2
  • 6
    • 77949873622 scopus 로고    scopus 로고
    • An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells
    • [Research Support, Non-U.S. Gov't]
    • Lee W.Y., Moriarty T.J., Wong C.H., Zhou H., Strieter R.M., van Rooijen N., et al. An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat Immunol Apr 2010, 11(4):295-302. [Research Support, Non-U.S. Gov't].
    • (2010) Nat Immunol , vol.11 , Issue.4 , pp. 295-302
    • Lee, W.Y.1    Moriarty, T.J.2    Wong, C.H.3    Zhou, H.4    Strieter, R.M.5    van Rooijen, N.6
  • 7
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Scott E.W., Simon M.C., Anastasi J., Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science Sep 9 1994, 265(5178):1573-1577. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (1994) Science , vol.265 , Issue.5178 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 8
    • 0033135269 scopus 로고    scopus 로고
    • The bHLH gene Hes1 is essential for expansion of early T cell precursors
    • [Research Support, Non-U.S. Gov't]
    • Tomita K., Hattori M., Nakamura E., Nakanishi S., Minato N., Kageyama R. The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev May 1 1999, 13(9):1203-1210. [Research Support, Non-U.S. Gov't].
    • (1999) Genes Dev , vol.13 , Issue.9 , pp. 1203-1210
    • Tomita, K.1    Hattori, M.2    Nakamura, E.3    Nakanishi, S.4    Minato, N.5    Kageyama, R.6
  • 9
    • 73949143689 scopus 로고    scopus 로고
    • GATA-3 is required for early T lineage progenitor development
    • [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
    • Hosoya T., Kuroha T., Moriguchi T., Cummings D., Maillard I., Lim K.C., et al. GATA-3 is required for early T lineage progenitor development. J Exp Med Dec 21 2009, 206(13):2987-3000. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't].
    • (2009) J Exp Med , vol.206 , Issue.13 , pp. 2987-3000
    • Hosoya, T.1    Kuroha, T.2    Moriguchi, T.3    Cummings, D.4    Maillard, I.5    Lim, K.C.6
  • 10
    • 0043239343 scopus 로고    scopus 로고
    • Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb
    • [Research Support, Non-U.S. Gov't]
    • Emambokus N., Vegiopoulos A., Harman B., Jenkinson E., Anderson G., Frampton J. Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. EMBO J Sep 1 2003, 22(17):4478-4488. [Research Support, Non-U.S. Gov't].
    • (2003) EMBO J , vol.22 , Issue.17 , pp. 4478-4488
    • Emambokus, N.1    Vegiopoulos, A.2    Harman, B.3    Jenkinson, E.4    Anderson, G.5    Frampton, J.6
  • 11
    • 0028001362 scopus 로고
    • The Ikaros gene is required for the development of all lymphoid lineages
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Georgopoulos K., Bigby M., Wang J.H., Molnar A., Wu P., Winandy S., et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell Oct 7 1994, 79(1):143-156. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (1994) Cell , vol.79 , Issue.1 , pp. 143-156
    • Georgopoulos, K.1    Bigby, M.2    Wang, J.H.3    Molnar, A.4    Wu, P.5    Winandy, S.6
  • 12
    • 35548939080 scopus 로고    scopus 로고
    • Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors
    • [Research Support, Non-U.S. Gov't]
    • Sitnicka E., Buza-Vidas N., Ahlenius H., Cilio C.M., Gekas C., Nygren J.M., et al. Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors. Blood Oct 15 2007, 110(8):2955-2964. [Research Support, Non-U.S. Gov't].
    • (2007) Blood , vol.110 , Issue.8 , pp. 2955-2964
    • Sitnicka, E.1    Buza-Vidas, N.2    Ahlenius, H.3    Cilio, C.M.4    Gekas, C.5    Nygren, J.M.6
  • 13
    • 52549124338 scopus 로고    scopus 로고
    • Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate
    • [Research Support, Non-U.S. Gov't]
    • Muroi S., Naoe Y., Miyamoto C., Akiyama K., Ikawa T., Masuda K., et al. Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat Immunol Oct 2008, 9(10):1113-1121. [Research Support, Non-U.S. Gov't].
    • (2008) Nat Immunol , vol.9 , Issue.10 , pp. 1113-1121
    • Muroi, S.1    Naoe, Y.2    Miyamoto, C.3    Akiyama, K.4    Ikawa, T.5    Masuda, K.6
  • 14
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • [Comparative Study Research Support, Non-U.S. Gov't]
    • Taniuchi I., Osato M., Egawa T., Sunshine M.J., Bae S.C., Komori T., et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell Nov 27 2002, 111(5):621-633. [Comparative Study Research Support, Non-U.S. Gov't].
    • (2002) Cell , vol.111 , Issue.5 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    Egawa, T.3    Sunshine, M.J.4    Bae, S.C.5    Komori, T.6
  • 15
    • 0014792798 scopus 로고
    • Cell interactions in the induction of tolerance: the role of thymic lymphocytes
    • Gershon R.K., Kondo K. Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology May 1970, 18(5):723-737.
    • (1970) Immunology , vol.18 , Issue.5 , pp. 723-737
    • Gershon, R.K.1    Kondo, K.2
  • 16
    • 0015118452 scopus 로고
    • Genetically determined immune deficiency as the predisposing cause of "autoimmunity" and lymphoid neoplasia
    • [Review]
    • Fudenberg H.H. Genetically determined immune deficiency as the predisposing cause of "autoimmunity" and lymphoid neoplasia. Am J Med Sep 1971, 51(3):295-298. [Review].
    • (1971) Am J Med , vol.51 , Issue.3 , pp. 295-298
    • Fudenberg, H.H.1
  • 17
    • 0016606672 scopus 로고
    • Active suppressor mechanism maintaining tolerance to some self components
    • Cunningham A.J. Active suppressor mechanism maintaining tolerance to some self components. Nature Mar 13 1975, 254(5496):143-144.
    • (1975) Nature , vol.254 , Issue.5496 , pp. 143-144
    • Cunningham, A.J.1
  • 18
    • 0015230357 scopus 로고
    • Cooperating and controlling functions of thymus-derived lymphocytes in relation to autoimmunity
    • [Review]
    • Allison A.C., Denman A.M., Barnes R.D. Cooperating and controlling functions of thymus-derived lymphocytes in relation to autoimmunity. Lancet Jul 17 1971, 2(7716):135-140. [Review].
    • (1971) Lancet , vol.2 , Issue.7716 , pp. 135-140
    • Allison, A.C.1    Denman, A.M.2    Barnes, R.D.3
  • 19
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., Sakaguchi N., Asano M., Itoh M., Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol Aug 1 1995, 155(3):1151-1164.
    • (1995) J Immunol , vol.155 , Issue.3 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 20
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton A., Shevach E. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998, 188(2):287-296.
    • (1998) J Exp Med , vol.188 , Issue.2 , pp. 287-296
    • Thornton, A.1    Shevach, E.2
  • 21
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton A., Shevach E. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 2000, 164(1):183-190.
    • (2000) J Immunol , vol.164 , Issue.1 , pp. 183-190
    • Thornton, A.1    Shevach, E.2
  • 22
    • 0035806323 scopus 로고    scopus 로고
    • Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • Levings M.K., Sangregorio R., Roncarolo M.G. Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med Jun 4 2001, 193(11):1295-1302.
    • (2001) J Exp Med , vol.193 , Issue.11 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 23
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann D., Plottner H., Berchtold S., Berger T., Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001, 193(11):1303-1310.
    • (2001) J Exp Med , vol.193 , Issue.11 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 24
    • 0035413350 scopus 로고    scopus 로고
    • CD4+ CD25high regulatory cells in human peripheral blood
    • Baecher-Allan C., Brown J., Freeman G., Hafler D. CD4+ CD25high regulatory cells in human peripheral blood. J Immunol 2001, 167(3):1245-1253.
    • (2001) J Immunol , vol.167 , Issue.3 , pp. 1245-1253
    • Baecher-Allan, C.1    Brown, J.2    Freeman, G.3    Hafler, D.4
  • 25
    • 84861880306 scopus 로고    scopus 로고
    • Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells
    • Tai X., Van Laethem F., Pobezinsky L., Guinter T., Sharrow S., Adams A., et al. Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells. Blood 2012, 119(22):5155-5163.
    • (2012) Blood , vol.119 , Issue.22 , pp. 5155-5163
    • Tai, X.1    Van Laethem, F.2    Pobezinsky, L.3    Guinter, T.4    Sharrow, S.5    Adams, A.6
  • 26
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J., Yamazaki S., Takahashi T., Ishida Y., Sakaguchi S. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol Feb 2002, 3(2):135-142.
    • (2002) Nat Immunol , vol.3 , Issue.2 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 27
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh R.S., Whitters M.J., Piccirillo C.A., Young D.A., Shevach E.M., Collins M., et al. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity Feb 2002, 16(2):311-323.
    • (2002) Immunity , vol.16 , Issue.2 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3    Young, D.A.4    Shevach, E.M.5    Collins, M.6
  • 28
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin R.S., Ramsdell F., Peake J., Faravelli F., Casanova J.L., Buist N., et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet Jan 2001, 27(1):18-20.
    • (2001) Nat Genet , vol.27 , Issue.1 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3    Faravelli, F.4    Casanova, J.L.5    Buist, N.6
  • 29
    • 44849100619 scopus 로고    scopus 로고
    • Is FOXP3 a bona fide marker for human regulatory T cells?
    • Roncarolo M., Gregori S. Is FOXP3 a bona fide marker for human regulatory T cells?. Eur J Immunol 2008, 38(4):925-927.
    • (2008) Eur J Immunol , vol.38 , Issue.4 , pp. 925-927
    • Roncarolo, M.1    Gregori, S.2
  • 30
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W., Putnam A.L., Xu-Yu Z., Szot G.L., Lee M.R., Zhu S., et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med Jul 10 2006, 203(7):1701-1711.
    • (2006) J Exp Med , vol.203 , Issue.7 , pp. 1701-1711
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3    Szot, G.L.4    Lee, M.R.5    Zhu, S.6
  • 31
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N., Santner-Nanan B., Martinson J., Zaunders J., Sasson S., Landay A., et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006, 203(7):1693-1700.
    • (2006) J Exp Med , vol.203 , Issue.7 , pp. 1693-1700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3    Zaunders, J.4    Sasson, S.5    Landay, A.6
  • 32
  • 33
    • 33644548654 scopus 로고    scopus 로고
    • Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells
    • Raimondi G., Shufesky W.J., Tokita D., Morelli A.E., Thomson A.W. Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells. J Immunol Mar 1 2006, 176(5):2808-2816.
    • (2006) J Immunol , vol.176 , Issue.5 , pp. 2808-2816
    • Raimondi, G.1    Shufesky, W.J.2    Tokita, D.3    Morelli, A.E.4    Thomson, A.W.5
  • 34
    • 34047238442 scopus 로고    scopus 로고
    • CD27 expression discriminates between regulatory and non-regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells
    • Duggleby R.C., Shaw T.N., Jarvis L.B., Kaur G., Gaston J.S. CD27 expression discriminates between regulatory and non-regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells. Immunology May 2007, 121(1):129-139.
    • (2007) Immunology , vol.121 , Issue.1 , pp. 129-139
    • Duggleby, R.C.1    Shaw, T.N.2    Jarvis, L.B.3    Kaur, G.4    Gaston, J.S.5
  • 35
    • 36248976097 scopus 로고    scopus 로고
    • CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells
    • Pandiyan P., Zheng L., Ishihara S., Reed J., Lenardo M.J. CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells. Nat Immunol Dec 2007, 8(12):1353-1362.
    • (2007) Nat Immunol , vol.8 , Issue.12 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 36
    • 33746933828 scopus 로고    scopus 로고
    • TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling
    • Oida T., Xu L., Weiner H.L., Kitani A., Strober W. TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling. J Immunol Aug 15 2006, 177(4):2331-2339.
    • (2006) J Immunol , vol.177 , Issue.4 , pp. 2331-2339
    • Oida, T.1    Xu, L.2    Weiner, H.L.3    Kitani, A.4    Strober, W.5
  • 38
    • 34249701932 scopus 로고    scopus 로고
    • ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells
    • Bodor J., Fehervari Z., Diamond B., Sakaguchi S. ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells. Eur J Immunol 2007, 37(4):884-895.
    • (2007) Eur J Immunol , vol.37 , Issue.4 , pp. 884-895
    • Bodor, J.1    Fehervari, Z.2    Diamond, B.3    Sakaguchi, S.4
  • 39
    • 3142708571 scopus 로고    scopus 로고
    • Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
    • Paust S., Lu L., McCarty N., Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A 2004, 101(28):10398-10403.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.28 , pp. 10398-10403
    • Paust, S.1    Lu, L.2    McCarty, N.3    Cantor, H.4
  • 40
    • 33847337912 scopus 로고    scopus 로고
    • Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta
    • Liu V.C., Wong L.Y., Jang T., Shah A.H., Park I., Yang X., et al. Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J Immunol Mar 1 2007, 178(5):2883-2892.
    • (2007) J Immunol , vol.178 , Issue.5 , pp. 2883-2892
    • Liu, V.C.1    Wong, L.Y.2    Jang, T.3    Shah, A.H.4    Park, I.5    Yang, X.6
  • 41
    • 4744356110 scopus 로고    scopus 로고
    • TGF-beta induces Foxp3+ T-regulatory cells from CD4+CD25- precursors
    • Fu S., Zhang N., Yopp A.C., Chen D., Mao M., Chen D., et al. TGF-beta induces Foxp3+ T-regulatory cells from CD4+CD25- precursors. Am J Transplant Oct 2004, 4(10):1614-1627.
    • (2004) Am J Transplant , vol.4 , Issue.10 , pp. 1614-1627
    • Fu, S.1    Zhang, N.2    Yopp, A.C.3    Chen, D.4    Mao, M.5    Chen, D.6
  • 42
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med Dec 15 2003, 198(12):1875-1886.
    • (2003) J Exp Med , vol.198 , Issue.12 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6
  • 43
    • 34250216635 scopus 로고    scopus 로고
    • A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta
    • Selvaraj R.K., Geiger T.L. A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J Immunol Jun 15 2007, 178(12):7667-7677.
    • (2007) J Immunol , vol.178 , Issue.12 , pp. 7667-7677
    • Selvaraj, R.K.1    Geiger, T.L.2
  • 44
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
    • Fantini M., Becker C., Monteleone G., Pallone F., Galle P., Neurath M. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 2004, 172(9):5149-5153.
    • (2004) J Immunol , vol.172 , Issue.9 , pp. 5149-5153
    • Fantini, M.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.5    Neurath, M.6
  • 45
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H., O'Garra A., Bigler M., Rouleau M., Antonenko S., de Vries J., et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997, 389(6652):737-742.
    • (1997) Nature , vol.389 , Issue.6652 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5    de Vries, J.6
  • 48
    • 0347895101 scopus 로고    scopus 로고
    • Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
    • Kemper C., Chan A.C., Green J.M., Brett K.A., Murphy K.M., Atkinson J.P. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature Jan 23 2003, 421(6921):388-392.
    • (2003) Nature , vol.421 , Issue.6921 , pp. 388-392
    • Kemper, C.1    Chan, A.C.2    Green, J.M.3    Brett, K.A.4    Murphy, K.M.5    Atkinson, J.P.6
  • 49
    • 69249083836 scopus 로고    scopus 로고
    • Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
    • Pot C., Jin H., Awasthi A., Liu S., Lai C., Madan R., et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J Immunol 2009, 183(2):797-801.
    • (2009) J Immunol , vol.183 , Issue.2 , pp. 797-801
    • Pot, C.1    Jin, H.2    Awasthi, A.3    Liu, S.4    Lai, C.5    Madan, R.6
  • 50
    • 12844274909 scopus 로고    scopus 로고
    • Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells
    • Levings M., Gregori S., Tresoldi E., Cazzaniga S., Bonini C., Roncarolo M. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood 2005, 105(3):1162-1169.
    • (2005) Blood , vol.105 , Issue.3 , pp. 1162-1169
    • Levings, M.1    Gregori, S.2    Tresoldi, E.3    Cazzaniga, S.4    Bonini, C.5    Roncarolo, M.6
  • 51
    • 63849205165 scopus 로고    scopus 로고
    • Desmoglein 3-specific T regulatory 1 cells consist of two subpopulations with differential expression of the transcription factor Foxp3
    • Veldman C., Pahl A., Hertl M. Desmoglein 3-specific T regulatory 1 cells consist of two subpopulations with differential expression of the transcription factor Foxp3. Immunology 2009, 127(1):40-49.
    • (2009) Immunology , vol.127 , Issue.1 , pp. 40-49
    • Veldman, C.1    Pahl, A.2    Hertl, M.3
  • 52
    • 79953038851 scopus 로고    scopus 로고
    • Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome
    • Passerini L., Di Nunzio S., Gregori S., Gambineri E., Cecconi M., Seidel M., et al. Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome. Eur J Immunol 2011, 41(4):1120-1131.
    • (2011) Eur J Immunol , vol.41 , Issue.4 , pp. 1120-1131
    • Passerini, L.1    Di Nunzio, S.2    Gregori, S.3    Gambineri, E.4    Cecconi, M.5    Seidel, M.6
  • 53
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
    • Weiner H.L. Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol Rev Aug 2001, 182:207-214.
    • (2001) Immunol Rev , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 54
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
    • Chen Y., Kuchroo V., Inobe J., Hafler D., Weiner H. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994, 265(5176):1237-1240.
    • (1994) Science , vol.265 , Issue.5176 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.2    Inobe, J.3    Hafler, D.4    Weiner, H.5
  • 55
    • 33845662118 scopus 로고    scopus 로고
    • Oral tolerance: therapeutic implications for autoimmune diseases
    • Faria A., Weiner H. Oral tolerance: therapeutic implications for autoimmune diseases. Clin Dev Immunol 2006, 13(2-4):143-157.
    • (2006) Clin Dev Immunol , vol.13 , Issue.2-4 , pp. 143-157
    • Faria, A.1    Weiner, H.2
  • 56
    • 33845915104 scopus 로고    scopus 로고
    • Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice
    • Carrier Y., Yuan J., Kuchroo V.K., Weiner H.L. Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice. J Immunol Jan 1 2007, 178(1):179-185.
    • (2007) J Immunol , vol.178 , Issue.1 , pp. 179-185
    • Carrier, Y.1    Yuan, J.2    Kuchroo, V.K.3    Weiner, H.L.4
  • 57
    • 0023192930 scopus 로고
    • A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family
    • Fowlkes B., Kruisbeek A., Ton-That H., Weston M., Coligan J., Schwartz R., et al. A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family. Nature 1987, 329(6136):251-254.
    • (1987) Nature , vol.329 , Issue.6136 , pp. 251-254
    • Fowlkes, B.1    Kruisbeek, A.2    Ton-That, H.3    Weston, M.4    Coligan, J.5    Schwartz, R.6
  • 58
    • 20144388310 scopus 로고    scopus 로고
    • Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells
    • Fischer K., Voelkl S., Heymann J., Przybylski G.K., Mondal K., Laumer M., et al. Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells. Blood Apr 1 2005, 105(7):2828-2835.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2828-2835
    • Fischer, K.1    Voelkl, S.2    Heymann, J.3    Przybylski, G.K.4    Mondal, K.5    Laumer, M.6
  • 59
    • 33747760388 scopus 로고    scopus 로고
    • Double-negative T regulatory cells can develop outside the thymus and do not mature from CD8+ T cell precursors
    • Ford M.S., Zhang Z.X., Chen W., Zhang L. Double-negative T regulatory cells can develop outside the thymus and do not mature from CD8+ T cell precursors. J Immunol Sep 1 2006, 177(5):2803-2809.
    • (2006) J Immunol , vol.177 , Issue.5 , pp. 2803-2809
    • Ford, M.S.1    Zhang, Z.X.2    Chen, W.3    Zhang, L.4
  • 60
    • 34247359509 scopus 로고    scopus 로고
    • New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses
    • Zhang D., Yang W., Degauque N., Tian Y., Mikita A., Zheng X.X. New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses. Blood May 1 2007, 109(9):4071-4079.
    • (2007) Blood , vol.109 , Issue.9 , pp. 4071-4079
    • Zhang, D.1    Yang, W.2    Degauque, N.3    Tian, Y.4    Mikita, A.5    Zheng, X.X.6
  • 61
    • 37549007140 scopus 로고    scopus 로고
    • Donor double-negative Treg promote allogeneic mixed chimerism and tolerance
    • He K., Ma Y., Wang S., Min W., Zhong R., Jevnikar A., et al. Donor double-negative Treg promote allogeneic mixed chimerism and tolerance. Eur J Immunol 2007, 37(12):3455-3466.
    • (2007) Eur J Immunol , vol.37 , Issue.12 , pp. 3455-3466
    • He, K.1    Ma, Y.2    Wang, S.3    Min, W.4    Zhong, R.5    Jevnikar, A.6
  • 62
    • 79954630416 scopus 로고    scopus 로고
    • Consequences of double negative regulatory T cell and antigen presenting cell interaction on immune response suppression
    • Ford McIntyre M., Gao J., Li X., Naeini B., Zhang L. Consequences of double negative regulatory T cell and antigen presenting cell interaction on immune response suppression. Int Immunopharmacol 2010, 11(5):597-603.
    • (2010) Int Immunopharmacol , vol.11 , Issue.5 , pp. 597-603
    • Ford McIntyre, M.1    Gao, J.2    Li, X.3    Naeini, B.4    Zhang, L.5
  • 63
    • 80052151755 scopus 로고    scopus 로고
    • Regulation of antigen-expressing dendritic cells by double negative regulatory T cells
    • Gao J., McIntyre M., Juvet S., Diao J., Li X., Vanama R., et al. Regulation of antigen-expressing dendritic cells by double negative regulatory T cells. Eur J Immunol 2011, 41(9):2699-2708.
    • (2011) Eur J Immunol , vol.41 , Issue.9 , pp. 2699-2708
    • Gao, J.1    McIntyre, M.2    Juvet, S.3    Diao, J.4    Li, X.5    Vanama, R.6
  • 64
    • 80053329222 scopus 로고    scopus 로고
    • Cell therapy with autologous tolerogenic dendritic cells induces allograft tolerance through interferon-gamma and Epstein-Barr virus-induced gene 3
    • Hill M., Thebault P., Segovia M., Louvet C., Bériou G., Tilly G., et al. Cell therapy with autologous tolerogenic dendritic cells induces allograft tolerance through interferon-gamma and Epstein-Barr virus-induced gene 3. Am J Transplant 2011, 11(10):2036-2045.
    • (2011) Am J Transplant , vol.11 , Issue.10 , pp. 2036-2045
    • Hill, M.1    Thebault, P.2    Segovia, M.3    Louvet, C.4    Bériou, G.5    Tilly, G.6
  • 65
    • 0035932949 scopus 로고    scopus 로고
    • CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice
    • Jiang H., Braunstein N., Yu B., Winchester R., Chess L. CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice. Proc Natl Acad Sci U S A 2001, 98(11):6301-6306.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.11 , pp. 6301-6306
    • Jiang, H.1    Braunstein, N.2    Yu, B.3    Winchester, R.4    Chess, L.5
  • 66
    • 77957855176 scopus 로고    scopus 로고
    • HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes
    • Jiang H., Canfield S., Gallagher M., Jiang H., Jiang Y., Zheng Z., et al. HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes. J Clin Invest 2010, 120(10):3641-3650.
    • (2010) J Clin Invest , vol.120 , Issue.10 , pp. 3641-3650
    • Jiang, H.1    Canfield, S.2    Gallagher, M.3    Jiang, H.4    Jiang, Y.5    Zheng, Z.6
  • 67
    • 20444485236 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma
    • Wei S., Kryczek I., Zou L., Daniel B., Cheng P., Mottram P., et al. Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma. Cancer Res Jun 15 2005, 65(12):5020-5026.
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5020-5026
    • Wei, S.1    Kryczek, I.2    Zou, L.3    Daniel, B.4    Cheng, P.5    Mottram, P.6
  • 68
    • 84865418657 scopus 로고    scopus 로고
    • CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells
    • Suzuki M., Jagger A., Konya C., Shimojima Y., Pryshchep S., Goronzy J., et al. CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells. J Immunol 2012, 189(5):2118-2130.
    • (2012) J Immunol , vol.189 , Issue.5 , pp. 2118-2130
    • Suzuki, M.1    Jagger, A.2    Konya, C.3    Shimojima, Y.4    Pryshchep, S.5    Goronzy, J.6
  • 69
    • 59849119691 scopus 로고    scopus 로고
    • CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1
    • Han Y., Guo Q., Zhang M., Chen Z., Cao X. CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J Immunol 2009, 182(1):111-120.
    • (2009) J Immunol , vol.182 , Issue.1 , pp. 111-120
    • Han, Y.1    Guo, Q.2    Zhang, M.3    Chen, Z.4    Cao, X.5
  • 70
    • 84880920680 scopus 로고    scopus 로고
    • Tumor microenvironment and myeloid-derived suppressor cells
    • (in press)
    • Umansky V., Sevko A. Tumor microenvironment and myeloid-derived suppressor cells. Cancer Micrenviron Dec 2012, (in press). 10.1007/s12307-012-0126-7.
    • (2012) Cancer Micrenviron
    • Umansky, V.1    Sevko, A.2
  • 71
    • 78649586268 scopus 로고    scopus 로고
    • The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity
    • Youn J., Gabrilovich D. The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur J Immunol 2010, 40(11):2969-2975.
    • (2010) Eur J Immunol , vol.40 , Issue.11 , pp. 2969-2975
    • Youn, J.1    Gabrilovich, D.2
  • 72
    • 84865552100 scopus 로고    scopus 로고
    • Immuno-oncology: understanding the function and dysfunction of the immune system in cancer
    • Finn O. Immuno-oncology: understanding the function and dysfunction of the immune system in cancer. Ann Oncol 2012, 23(Suppl. 8):viii6-viii9.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 8
    • Finn, O.1
  • 73
    • 34247261531 scopus 로고    scopus 로고
    • Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • Bates G.J., Fox S.B., Han C., Leek R.D., Garcia J.F., Harris A.L., et al. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol Dec 1 2006, 24(34):5373-5380.
    • (2006) J Clin Oncol , vol.24 , Issue.34 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3    Leek, R.D.4    Garcia, J.F.5    Harris, A.L.6
  • 74
    • 84862318552 scopus 로고    scopus 로고
    • Regulatory T cells increase in breast cancer and in stage IV breast cancer
    • Wang Z., Yang B., Liu H., Hu Y., Yang J., Wu L., et al. Regulatory T cells increase in breast cancer and in stage IV breast cancer. Cancer Immunol Immunother 2012, 61(6):911-916.
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.6 , pp. 911-916
    • Wang, Z.1    Yang, B.2    Liu, H.3    Hu, Y.4    Yang, J.5    Wu, L.6
  • 75
    • 79952193038 scopus 로고    scopus 로고
    • Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
    • Tan W., Zhang W., Strasner A., Grivennikov S., Cheng J., Hoffman R., et al. Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature 2011, 470(7335):548-553.
    • (2011) Nature , vol.470 , Issue.7335 , pp. 548-553
    • Tan, W.1    Zhang, W.2    Strasner, A.3    Grivennikov, S.4    Cheng, J.5    Hoffman, R.6
  • 76
    • 84865519693 scopus 로고    scopus 로고
    • Monocyte-derived dendritic cells from breast cancer patients are biased to induce CD4+CD25+Foxp3+ regulatory T cells
    • Ramos R., Chin L., Dos Santos A., Bergami-Santos P., Laginha F., Barbuto J. Monocyte-derived dendritic cells from breast cancer patients are biased to induce CD4+CD25+Foxp3+ regulatory T cells. J Leukoc Biol 2012, 92(3):673-682.
    • (2012) J Leukoc Biol , vol.92 , Issue.3 , pp. 673-682
    • Ramos, R.1    Chin, L.2    Dos Santos, A.3    Bergami-Santos, P.4    Laginha, F.5    Barbuto, J.6
  • 77
    • 80052214987 scopus 로고    scopus 로고
    • Skewing the balance of regulatory T-cells and T-helper 17 cells in breast cancer patients
    • Wang J., Cai D., Ma B., Wu G., Wu J. Skewing the balance of regulatory T-cells and T-helper 17 cells in breast cancer patients. J Int Med Res 2011, 39(3):691-701.
    • (2011) J Int Med Res , vol.39 , Issue.3 , pp. 691-701
    • Wang, J.1    Cai, D.2    Ma, B.3    Wu, G.4    Wu, J.5
  • 78
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel T.J., Coukos G., Zou L., Alvarez X., Cheng P., Mottram P., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med Sep 2004, 10(9):942-949.
    • (2004) Nat Med , vol.10 , Issue.9 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6
  • 79
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
    • Wolf D., Wolf A., Rumpold H., Fiegl H., Zeimet A., Muller-Holzner E., et al. The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res 2005, 11(23):8326-8331.
    • (2005) Clin Cancer Res , vol.11 , Issue.23 , pp. 8326-8331
    • Wolf, D.1    Wolf, A.2    Rumpold, H.3    Fiegl, H.4    Zeimet, A.5    Muller-Holzner, E.6
  • 80
    • 84872872011 scopus 로고    scopus 로고
    • Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
    • Fialová A., Partlová S., Sojka L., Hromádková H., Brtnický T., Fučíková J., et al. Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells. Int J Cancer 2012, 10.1002/ijc.27759.
    • (2012) Int J Cancer
    • Fialová, A.1    Partlová, S.2    Sojka, L.3    Hromádková, H.4    Brtnický, T.5    Fučíková, J.6
  • 81
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
    • Kryczek I., Banerjee M., Cheng P., Vatan L., Szeliga W., Wei S., et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009, 114(6):1141-1149.
    • (2009) Blood , vol.114 , Issue.6 , pp. 1141-1149
    • Kryczek, I.1    Banerjee, M.2    Cheng, P.3    Vatan, L.4    Szeliga, W.5    Wei, S.6
  • 82
    • 33750807427 scopus 로고    scopus 로고
    • CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
    • Miller A.M., Lundberg K., Ozenci V., Banham A.H., Hellstrom M., Egevad L., et al. CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. J Immunol Nov 15 2006, 177(10):7398-7405.
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 7398-7405
    • Miller, A.M.1    Lundberg, K.2    Ozenci, V.3    Banham, A.H.4    Hellstrom, M.5    Egevad, L.6
  • 83
    • 39749142196 scopus 로고    scopus 로고
    • Enhanced functionality of CD4+CD25(high)FoxP3+ regulatory T cells in the peripheral blood of patients with prostate cancer
    • Yokokawa J., Cereda V., Remondo C., Gulley J., Arlen P., Schlom J., et al. Enhanced functionality of CD4+CD25(high)FoxP3+ regulatory T cells in the peripheral blood of patients with prostate cancer. Clin Cancer Res 2008, 14(4):1032-1040.
    • (2008) Clin Cancer Res , vol.14 , Issue.4 , pp. 1032-1040
    • Yokokawa, J.1    Cereda, V.2    Remondo, C.3    Gulley, J.4    Arlen, P.5    Schlom, J.6
  • 84
    • 79151474414 scopus 로고    scopus 로고
    • Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre- versus post-vaccination
    • Vergati M., Cereda V., Madan R., Gulley J., Huen N., Rogers C., et al. Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre- versus post-vaccination. Cancer Immunol Immunother 2011, 60(2):197-206.
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.2 , pp. 197-206
    • Vergati, M.1    Cereda, V.2    Madan, R.3    Gulley, J.4    Huen, N.5    Rogers, C.6
  • 85
    • 84871718282 scopus 로고    scopus 로고
    • Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer
    • Zhao E., Wang L., Dai J., Kryczek I., Wei S., Vatan L., et al. Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer. Oncoimmunology 2012, 1(2):152-161.
    • (2012) Oncoimmunology , vol.1 , Issue.2 , pp. 152-161
    • Zhao, E.1    Wang, L.2    Dai, J.3    Kryczek, I.4    Wei, S.5    Vatan, L.6
  • 86
    • 34047141055 scopus 로고    scopus 로고
    • Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients
    • Ling K.L., Pratap S.E., Bates G.J., Singh B., Mortensen N.J., George B.D., et al. Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients. Cancer Immun 2007, 7:7.
    • (2007) Cancer Immun , vol.7 , pp. 7
    • Ling, K.L.1    Pratap, S.E.2    Bates, G.J.3    Singh, B.4    Mortensen, N.J.5    George, B.D.6
  • 87
    • 84872932778 scopus 로고    scopus 로고
    • Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer
    • [Epub ahead of print]
    • Lin Y., Mahalingam J., Chiang J., Su P., Chu Y., Lai H., et al. Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer. Int J Cancer 2012, [Epub ahead of print]. 10.1002/ijc.27784.
    • (2012) Int J Cancer
    • Lin, Y.1    Mahalingam, J.2    Chiang, J.3    Su, P.4    Chu, Y.5    Lai, H.6
  • 88
    • 34548162594 scopus 로고    scopus 로고
    • Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival
    • Griffiths R.W., Elkord E., Gilham D.E., Ramani V., Clarke N., Stern P.L., et al. Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival. Cancer Immunol Immunother Nov 2007, 56(11):1743-1753.
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.11 , pp. 1743-1753
    • Griffiths, R.W.1    Elkord, E.2    Gilham, D.E.3    Ramani, V.4    Clarke, N.5    Stern, P.L.6
  • 89
    • 58149179532 scopus 로고    scopus 로고
    • Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients
    • Finke J., Rini B., Ireland J., Rayman P., Richmond A., Golshayan A., et al. Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients. Clin Cancer Res 2008, 14(20):6674-6682.
    • (2008) Clin Cancer Res , vol.14 , Issue.20 , pp. 6674-6682
    • Finke, J.1    Rini, B.2    Ireland, J.3    Rayman, P.4    Richmond, A.5    Golshayan, A.6
  • 90
    • 78149281950 scopus 로고    scopus 로고
    • A decrease of regulatory T cells correlates with overall survival after sunitinib-based antiangiogenic therapy in metastatic renal cancer patients
    • Adotevi O., Pere H., Ravel P., Haicheur N., Badoual C., Merillon N., et al. A decrease of regulatory T cells correlates with overall survival after sunitinib-based antiangiogenic therapy in metastatic renal cancer patients. J Immunother 2010, 33(9):991-998.
    • (2010) J Immunother , vol.33 , Issue.9 , pp. 991-998
    • Adotevi, O.1    Pere, H.2    Ravel, P.3    Haicheur, N.4    Badoual, C.5    Merillon, N.6
  • 91
    • 61349195299 scopus 로고    scopus 로고
    • Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma
    • Jensen H., Donskov F., Nordsmark M., Marcussen N., von der Maase H. Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma. Clin Cancer Res 2009, 15(3):1052-1058.
    • (2009) Clin Cancer Res , vol.15 , Issue.3 , pp. 1052-1058
    • Jensen, H.1    Donskov, F.2    Nordsmark, M.3    Marcussen, N.4    von der Maase, H.5
  • 92
    • 34250198303 scopus 로고    scopus 로고
    • Melanoma induces immunosuppression by up-regulating FOXP3(+) regulatory T cells
    • Baumgartner J., Wilson C., Palmer B., Richter D., Banerjee A., McCarter M. Melanoma induces immunosuppression by up-regulating FOXP3(+) regulatory T cells. J Surg Res Jul 2007, 141(1):72-77.
    • (2007) J Surg Res , vol.141 , Issue.1 , pp. 72-77
    • Baumgartner, J.1    Wilson, C.2    Palmer, B.3    Richter, D.4    Banerjee, A.5    McCarter, M.6
  • 93
    • 3142737258 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • Viguier M., Lemaitre F., Verola O., Cho M.S., Gorochov G., Dubertret L., et al. Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol Jul 15 2004, 173(2):1444-1453.
    • (2004) J Immunol , vol.173 , Issue.2 , pp. 1444-1453
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3    Cho, M.S.4    Gorochov, G.5    Dubertret, L.6
  • 94
    • 58149399352 scopus 로고    scopus 로고
    • FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions
    • Ahmadzadeh M., Felipe-Silva A., Heemskerk B., Powell D.J., Wunderlich J.R., Merino M.J., et al. FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions. Blood Sep 26 2008, 112(13):4953-4960.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4953-4960
    • Ahmadzadeh, M.1    Felipe-Silva, A.2    Heemskerk, B.3    Powell, D.J.4    Wunderlich, J.R.5    Merino, M.J.6
  • 95
    • 78649941232 scopus 로고    scopus 로고
    • Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells
    • Martin-Orozco N., Li Y., Wang Y., Liu S., Hwu P., Liu Y., et al. Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells. Cancer Res 2010, 70(23):9581-9590.
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9581-9590
    • Martin-Orozco, N.1    Li, Y.2    Wang, Y.3    Liu, S.4    Hwu, P.5    Liu, Y.6
  • 96
    • 36348953150 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival
    • Gjerdrum L.M., Woetmann A., Odum N., Burton C.M., Rossen K., Skovgaard G.L., et al. FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival. Leukemia Dec 2007, 21(12):2512-2518.
    • (2007) Leukemia , vol.21 , Issue.12 , pp. 2512-2518
    • Gjerdrum, L.M.1    Woetmann, A.2    Odum, N.3    Burton, C.M.4    Rossen, K.5    Skovgaard, G.L.6
  • 97
    • 38849133434 scopus 로고    scopus 로고
    • Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis
    • Lee N., Song E., Jang K., Choi H., Moon W., Kwon K., et al. Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis. Leuk Lymphoma 2008, 49(2):247-256.
    • (2008) Leuk Lymphoma , vol.49 , Issue.2 , pp. 247-256
    • Lee, N.1    Song, E.2    Jang, K.3    Choi, H.4    Moon, W.5    Kwon, K.6
  • 98
    • 40849126992 scopus 로고    scopus 로고
    • Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma
    • Tzankov A., Meier C., Hirschmann P., Went P., Pileri S.A., Dirnhofer S. Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma. Haematologica 2008, 93:193-200.
    • (2008) Haematologica , vol.93 , pp. 193-200
    • Tzankov, A.1    Meier, C.2    Hirschmann, P.3    Went, P.4    Pileri, S.A.5    Dirnhofer, S.6
  • 99
    • 33749576080 scopus 로고    scopus 로고
    • Immunoregulatory T cells in the peripheral blood of patients with Hodgkin's lymphoma
    • Barath S., Aleksza M., Keresztes K., Toth J., Sipka S., Szegedi G., et al. Immunoregulatory T cells in the peripheral blood of patients with Hodgkin's lymphoma. Acta Haematol 2006, 116(3):181-185.
    • (2006) Acta Haematol , vol.116 , Issue.3 , pp. 181-185
    • Barath, S.1    Aleksza, M.2    Keresztes, K.3    Toth, J.4    Sipka, S.5    Szegedi, G.6
  • 100
    • 33947275359 scopus 로고    scopus 로고
    • The relationships between Epstein-Barr virus latent membrane protein 1 and regulatory T cells in Hodgkin's lymphoma
    • Marshall N.A., Culligan D.J., Tighe J., Johnston P.W., Barker R.N., Vickers M.A. The relationships between Epstein-Barr virus latent membrane protein 1 and regulatory T cells in Hodgkin's lymphoma. Exp Hematol Apr 2007, 35(4):596-604.
    • (2007) Exp Hematol , vol.35 , Issue.4 , pp. 596-604
    • Marshall, N.A.1    Culligan, D.J.2    Tighe, J.3    Johnston, P.W.4    Barker, R.N.5    Vickers, M.A.6
  • 101
    • 46749136862 scopus 로고    scopus 로고
    • Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates up-regulation of CCL20 and the migration of regulatory T cells
    • Baumforth K., Birgersdotter A., Reynolds G., Wei W., Kapatai G., Flavell J., et al. Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates up-regulation of CCL20 and the migration of regulatory T cells. Am J Pathol 2008, 173(1):195-204.
    • (2008) Am J Pathol , vol.173 , Issue.1 , pp. 195-204
    • Baumforth, K.1    Birgersdotter, A.2    Reynolds, G.3    Wei, W.4    Kapatai, G.5    Flavell, J.6
  • 102
    • 65249135978 scopus 로고    scopus 로고
    • Prognostic impact of tumour-infiltrating Th2 and regulatory T cells in classical Hodgkin lymphoma
    • Schreck S., Friebel D., Buettner M., Distel L., Grabenbauer G., Young L., et al. Prognostic impact of tumour-infiltrating Th2 and regulatory T cells in classical Hodgkin lymphoma. Hematol Oncol 2009, 17(1):31-39.
    • (2009) Hematol Oncol , vol.17 , Issue.1 , pp. 31-39
    • Schreck, S.1    Friebel, D.2    Buettner, M.3    Distel, L.4    Grabenbauer, G.5    Young, L.6
  • 103
    • 44749086828 scopus 로고    scopus 로고
    • Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma
    • Mittal S., Marshall N., Duncan L., Culligan D., Barker R., Vickers M. Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma. Blood 2008, 111(1):5359-5370.
    • (2008) Blood , vol.111 , Issue.1 , pp. 5359-5370
    • Mittal, S.1    Marshall, N.2    Duncan, L.3    Culligan, D.4    Barker, R.5    Vickers, M.6
  • 104
    • 83055164370 scopus 로고    scopus 로고
    • Malignant B cells induce the conversion of CD4+CD25- T cells to regulatory T cells in B-cell non-Hodgkin lymphoma
    • Han Y., Wu J., Bi L., Xiong S., Gao S., Yin L., et al. Malignant B cells induce the conversion of CD4+CD25- T cells to regulatory T cells in B-cell non-Hodgkin lymphoma. PLoS One 2011, 6(12):e28649.
    • (2011) PLoS One , vol.6 , Issue.12
    • Han, Y.1    Wu, J.2    Bi, L.3    Xiong, S.4    Gao, S.5    Yin, L.6
  • 105
    • 34249785092 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model
    • Elpek K., Lacelle C., Singh N., Yolcu E., Shirwan H. CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model. J Immunol 2007, 178(11):6840-6848.
    • (2007) J Immunol , vol.178 , Issue.11 , pp. 6840-6848
    • Elpek, K.1    Lacelle, C.2    Singh, N.3    Yolcu, E.4    Shirwan, H.5
  • 106
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini P., Mgebroff S., Noonan K., Borrello I. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res 2008, 68(13):5439-5449.
    • (2008) Cancer Res , vol.68 , Issue.13 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 107
    • 67650446560 scopus 로고    scopus 로고
    • Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma
    • Yang Z., Novak A., Ziesmer S., Witzig T., Ansell S. Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma. Cancer Res 2009, 69(13):5522-5530.
    • (2009) Cancer Res , vol.69 , Issue.13 , pp. 5522-5530
    • Yang, Z.1    Novak, A.2    Ziesmer, S.3    Witzig, T.4    Ansell, S.5
  • 108
    • 59449108329 scopus 로고    scopus 로고
    • Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study
    • Di Nicola M., Zappasodi R., Carlo-Stella C., Mortarini R., Pupa S., Magni M., et al. Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study. Blood 2009, 113(1):18-27.
    • (2009) Blood , vol.113 , Issue.1 , pp. 18-27
    • Di Nicola, M.1    Zappasodi, R.2    Carlo-Stella, C.3    Mortarini, R.4    Pupa, S.5    Magni, M.6
  • 109
    • 78649439306 scopus 로고    scopus 로고
    • T regulatory cells control T-cell proliferation partly by the release of soluble CD25 in patients with B-cell malignancies
    • Lindqvist C., Christiansson L., Simonsson B., Enblad G., Olsson-Strömberg U., Loskog A. T regulatory cells control T-cell proliferation partly by the release of soluble CD25 in patients with B-cell malignancies. Immunology 2010, 131(3):371-376.
    • (2010) Immunology , vol.131 , Issue.3 , pp. 371-376
    • Lindqvist, C.1    Christiansson, L.2    Simonsson, B.3    Enblad, G.4    Olsson-Strömberg, U.5    Loskog, A.6
  • 110
    • 83055181891 scopus 로고    scopus 로고
    • The four types of Tregs in malignant lymphomas
    • Wang J., Ke X. The four types of Tregs in malignant lymphomas. J Hematol Oncol 2011, 4(50). 10.1186/756-8722-4-50.
    • (2011) J Hematol Oncol , vol.4 , Issue.50
    • Wang, J.1    Ke, X.2
  • 111
    • 24744432528 scopus 로고    scopus 로고
    • Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
    • Beyer M., Kochanek M., Darabi K., Popov A., Jensen M., Endl E., et al. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood Sep 15 2005, 106(6):2018-2025.
    • (2005) Blood , vol.106 , Issue.6 , pp. 2018-2025
    • Beyer, M.1    Kochanek, M.2    Darabi, K.3    Popov, A.4    Jensen, M.5    Endl, E.6
  • 112
    • 79952100710 scopus 로고    scopus 로고
    • Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease
    • D'Arena G., Laurenti L., Minervini M., Deaglio S., Bonello L., De Martino L., et al. Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease. Leuk Res 2011, 35(3):363-368.
    • (2011) Leuk Res , vol.35 , Issue.3 , pp. 363-368
    • D'Arena, G.1    Laurenti, L.2    Minervini, M.3    Deaglio, S.4    Bonello, L.5    De Martino, L.6
  • 113
    • 68449093742 scopus 로고    scopus 로고
    • Enhanced formation and survival of CD4+ CD25hi Foxp3+ T-cells in chronic lymphocytic leukemia
    • Jak M., Mous R., Remmerswaal E., Spijker R., Jaspers A., Yagüe A., et al. Enhanced formation and survival of CD4+ CD25hi Foxp3+ T-cells in chronic lymphocytic leukemia. Leuk Lymphoma 2009, 50(5):788-801.
    • (2009) Leuk Lymphoma , vol.50 , Issue.5 , pp. 788-801
    • Jak, M.1    Mous, R.2    Remmerswaal, E.3    Spijker, R.4    Jaspers, A.5    Yagüe, A.6
  • 114
    • 46749132717 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug
    • [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
    • Ramsay A.G., Johnson A.J., Lee A.M., Gorgun G., Le Dieu R., Blum W., et al. Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug. J Clin Invest Jul 2008, 118(7):2427-2437. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't].
    • (2008) J Clin Invest , vol.118 , Issue.7 , pp. 2427-2437
    • Ramsay, A.G.1    Johnson, A.J.2    Lee, A.M.3    Gorgun, G.4    Le Dieu, R.5    Blum, W.6
  • 115
    • 34547957665 scopus 로고    scopus 로고
    • CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS)
    • Kordasti S.Y., Ingram W., Hayden J., Darling D., Barber L., Afzali B., et al. CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS). Blood Aug 1 2007, 110(3):847-850.
    • (2007) Blood , vol.110 , Issue.3 , pp. 847-850
    • Kordasti, S.Y.1    Ingram, W.2    Hayden, J.3    Darling, D.4    Barber, L.5    Afzali, B.6
  • 116
    • 58849142953 scopus 로고    scopus 로고
    • Clinical significance of regulatory T cells in patients with myelodysplastic syndrome
    • Hamdi W., Ogawara H., Handa H., Tsukamoto N., Nojima Y., Murakami H. Clinical significance of regulatory T cells in patients with myelodysplastic syndrome. Eur J Haematol 2009, 82(3):201-207.
    • (2009) Eur J Haematol , vol.82 , Issue.3 , pp. 201-207
    • Hamdi, W.1    Ogawara, H.2    Handa, H.3    Tsukamoto, N.4    Nojima, Y.5    Murakami, H.6
  • 117
    • 79960898228 scopus 로고    scopus 로고
    • Elevated frequencies of CD4+ CD25+ CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia
    • Shenghui Z., Yixiang H., Jianbo W., Kang Y., Laixi B., Yan Z., et al. Elevated frequencies of CD4+ CD25+ CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia. Int J Cancer 2010, 129(6):1373-1381.
    • (2010) Int J Cancer , vol.129 , Issue.6 , pp. 1373-1381
    • Shenghui, Z.1    Yixiang, H.2    Jianbo, W.3    Kang, Y.4    Laixi, B.5    Yan, Z.6
  • 118
    • 66149179122 scopus 로고    scopus 로고
    • Increased frequency and suppression by regulatory T cells in patients with acute myelogenous leukemia
    • Szczepanski M., Szajnik M., Czystowska M., Mandapathil M., Strauss L., Welsh A., et al. Increased frequency and suppression by regulatory T cells in patients with acute myelogenous leukemia. Clin Cancer Res 2009, 15(10):3325-3332.
    • (2009) Clin Cancer Res , vol.15 , Issue.10 , pp. 3325-3332
    • Szczepanski, M.1    Szajnik, M.2    Czystowska, M.3    Mandapathil, M.4    Strauss, L.5    Welsh, A.6
  • 119
    • 33947593164 scopus 로고    scopus 로고
    • Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells
    • Curti A., Pandolfi S., Valzasina B., Aluigi M., Isidori A., Ferri E., et al. Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells. Blood Apr 1 2007, 109(7):2871-2877.
    • (2007) Blood , vol.109 , Issue.7 , pp. 2871-2877
    • Curti, A.1    Pandolfi, S.2    Valzasina, B.3    Aluigi, M.4    Isidori, A.5    Ferri, E.6
  • 120
    • 78751526006 scopus 로고    scopus 로고
    • Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells
    • Kanakry C., Hess A., Gocke C., Thoburn C., Kos F., Meyer C., et al. Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells. Blood 2011, 117(2):608-617.
    • (2011) Blood , vol.117 , Issue.2 , pp. 608-617
    • Kanakry, C.1    Hess, A.2    Gocke, C.3    Thoburn, C.4    Kos, F.5    Meyer, C.6
  • 121
    • 24944449622 scopus 로고    scopus 로고
    • Immunotherapy in multiple myeloma - possibility or probability?
    • Harrison S.J., Cook G. Immunotherapy in multiple myeloma - possibility or probability?. Br J Haematol Aug 2005, 130(3):344-362.
    • (2005) Br J Haematol , vol.130 , Issue.3 , pp. 344-362
    • Harrison, S.J.1    Cook, G.2
  • 122
    • 0034017680 scopus 로고    scopus 로고
    • Immunogenicity of vaccination against influenza, Streptococcus pneumoniae and Haemophilus influenzae type B in patients with multiple myeloma
    • Robertson J.D., Nagesh K., Jowitt S.N., Dougal M., Anderson H., Mutton K., et al. Immunogenicity of vaccination against influenza, Streptococcus pneumoniae and Haemophilus influenzae type B in patients with multiple myeloma. Br J Cancer Apr 2000, 82(7):1261-1265.
    • (2000) Br J Cancer , vol.82 , Issue.7 , pp. 1261-1265
    • Robertson, J.D.1    Nagesh, K.2    Jowitt, S.N.3    Dougal, M.4    Anderson, H.5    Mutton, K.6
  • 123
    • 0032873880 scopus 로고    scopus 로고
    • Immune regulation in multiple myeloma: the host-tumour conflict
    • Cook G., Campbell J.D. Immune regulation in multiple myeloma: the host-tumour conflict. Blood Rev Sep 1999, 13(3):151-162.
    • (1999) Blood Rev , vol.13 , Issue.3 , pp. 151-162
    • Cook, G.1    Campbell, J.D.2
  • 124
    • 0033454740 scopus 로고    scopus 로고
    • Transforming growth factor beta from multiple myeloma cells inhibits proliferation and IL-2 responsiveness in T lymphocytes
    • Cook G., Campbell J.D., Carr C.E., Boyd K.S., Franklin I.M. Transforming growth factor beta from multiple myeloma cells inhibits proliferation and IL-2 responsiveness in T lymphocytes. J Leukoc Biol Dec 1999, 66(6):981-988.
    • (1999) J Leukoc Biol , vol.66 , Issue.6 , pp. 981-988
    • Cook, G.1    Campbell, J.D.2    Carr, C.E.3    Boyd, K.S.4    Franklin, I.M.5
  • 125
    • 33748750051 scopus 로고    scopus 로고
    • Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity
    • Kim R., Emi M., Tanabe K. Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity. Immunology Oct 2006, 119(2):254-264.
    • (2006) Immunology , vol.119 , Issue.2 , pp. 254-264
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 126
    • 0036659945 scopus 로고    scopus 로고
    • Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6
    • [Research Support, Non-U.S. Gov't]
    • Ratta M., Fagnoni F., Curti A., Vescovini R., Sansoni P., Oliviero B., et al. Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6. Blood Jul 1 2002, 100(1):230-237. [Research Support, Non-U.S. Gov't].
    • (2002) Blood , vol.100 , Issue.1 , pp. 230-237
    • Ratta, M.1    Fagnoni, F.2    Curti, A.3    Vescovini, R.4    Sansoni, P.5    Oliviero, B.6
  • 127
    • 0035892109 scopus 로고    scopus 로고
    • Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10
    • [Research Support, Non-U.S. Gov't]
    • Brown R.D., Pope B., Murray A., Esdale W., Sze D.M., Gibson J., et al. Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10. Blood Nov 15 2001, 98(10):2992-2998. [Research Support, Non-U.S. Gov't].
    • (2001) Blood , vol.98 , Issue.10 , pp. 2992-2998
    • Brown, R.D.1    Pope, B.2    Murray, A.3    Esdale, W.4    Sze, D.M.5    Gibson, J.6
  • 128
    • 3042691752 scopus 로고    scopus 로고
    • Either interleukin-12 or interferon-gamma can correct the dendritic cell defect induced by transforming growth factor beta in patients with myeloma
    • [Research Support, Non-U.S. Gov't]
    • Brown R., Murray A., Pope B., Sze D.M., Gibson J., Ho P.J., et al. Either interleukin-12 or interferon-gamma can correct the dendritic cell defect induced by transforming growth factor beta in patients with myeloma. Br J Haematol Jun 2004, 125(6):743-748. [Research Support, Non-U.S. Gov't].
    • (2004) Br J Haematol , vol.125 , Issue.6 , pp. 743-748
    • Brown, R.1    Murray, A.2    Pope, B.3    Sze, D.M.4    Gibson, J.5    Ho, P.J.6
  • 129
    • 78149270433 scopus 로고    scopus 로고
    • -/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
    • -/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma. Scand J Immunol 2010, 72(6):540-547.
    • (2010) Scand J Immunol , vol.72 , Issue.6 , pp. 540-547
    • Brimnes, M.1    Vangsted, A.2    Knudsen, L.3    Gimsing, P.4    Gang, A.5    Johnsen, H.6
  • 130
    • 33644757687 scopus 로고    scopus 로고
    • Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma
    • Wang S., Yang J., Qian J., Wezeman M., Kwak L.W., Yi Q. Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma. Blood Mar 15 2006, 107(6):2432-2439.
    • (2006) Blood , vol.107 , Issue.6 , pp. 2432-2439
    • Wang, S.1    Yang, J.2    Qian, J.3    Wezeman, M.4    Kwak, L.W.5    Yi, Q.6
  • 131
    • 25444439797 scopus 로고    scopus 로고
    • A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function
    • [Research Support, Non-U.S. Gov't]
    • Okunishi K., Dohi M., Nakagome K., Tanaka R., Mizuno S., Matsumoto K., et al. A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function. J Immunol Oct 1 2005, 175(7):4745-4753. [Research Support, Non-U.S. Gov't].
    • (2005) J Immunol , vol.175 , Issue.7 , pp. 4745-4753
    • Okunishi, K.1    Dohi, M.2    Nakagome, K.3    Tanaka, R.4    Mizuno, S.5    Matsumoto, K.6
  • 132
    • 80052781601 scopus 로고    scopus 로고
    • A novel role for Bruton's tyrosine kinase in hepatocyte growth factor-mediated immunoregulation of dendritic cells
    • [Research Support, Non-U.S. Gov't]
    • Singhal E., Kumar P., Sen P. A novel role for Bruton's tyrosine kinase in hepatocyte growth factor-mediated immunoregulation of dendritic cells. J Biol Chem Sep 16 2011, 286(37):32054-32063. [Research Support, Non-U.S. Gov't].
    • (2011) J Biol Chem , vol.286 , Issue.37 , pp. 32054-32063
    • Singhal, E.1    Kumar, P.2    Sen, P.3
  • 133
    • 77956581743 scopus 로고    scopus 로고
    • The cytokine/chemokine pattern in the bone marrow environment of multiple myeloma patients
    • [Research Support, Non-U.S. Gov't]
    • Cao Y., Luetkens T., Kobold S., Hildebrandt Y., Gordic M., Lajmi N., et al. The cytokine/chemokine pattern in the bone marrow environment of multiple myeloma patients. Exp Hematol Oct 2010, 38(10):860-867. [Research Support, Non-U.S. Gov't].
    • (2010) Exp Hematol , vol.38 , Issue.10 , pp. 860-867
    • Cao, Y.1    Luetkens, T.2    Kobold, S.3    Hildebrandt, Y.4    Gordic, M.5    Lajmi, N.6
  • 134
    • 33745616804 scopus 로고    scopus 로고
    • Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features
    • [Research Support, Non-U.S. Gov't]
    • Rutella S., Bonanno G., Procoli A., Mariotti A., de Ritis D.G., Curti A., et al. Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features. Blood Jul 1 2006, 108(1):218-227. [Research Support, Non-U.S. Gov't].
    • (2006) Blood , vol.108 , Issue.1 , pp. 218-227
    • Rutella, S.1    Bonanno, G.2    Procoli, A.3    Mariotti, A.4    de Ritis, D.G.5    Curti, A.6
  • 135
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • [Research Support, U.S. Gov't, P.H.S.]
    • Gabrilovich D., Ishida T., Oyama T., Ran S., Kravtsov V., Nadaf S., et al. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood Dec 1 1998, 92(11):4150-4166. [Research Support, U.S. Gov't, P.H.S.].
    • (1998) Blood , vol.92 , Issue.11 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3    Ran, S.4    Kravtsov, V.5    Nadaf, S.6
  • 136
    • 0038264409 scopus 로고    scopus 로고
    • Beta 2-microglobulin as a negative regulator of the immune system: high concentrations of the protein inhibit in vitro generation of functional dendritic cells
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Xie J., Wang Y., Freeman M.E., Barlogie B., Yi Q. Beta 2-microglobulin as a negative regulator of the immune system: high concentrations of the protein inhibit in vitro generation of functional dendritic cells. Blood May 15 2003, 101(10):4005-4012. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (2003) Blood , vol.101 , Issue.10 , pp. 4005-4012
    • Xie, J.1    Wang, Y.2    Freeman, M.E.3    Barlogie, B.4    Yi, Q.5
  • 137
    • 14044259353 scopus 로고    scopus 로고
    • Augmented induction of CD4+CD25+ Treg using monoclonal antibodies to CD200R
    • Gorczynski R.M., Lee L., Boudakov I. Augmented induction of CD4+CD25+ Treg using monoclonal antibodies to CD200R. Transplantation May 15 2005, 79(9):1180-1183.
    • (2005) Transplantation , vol.79 , Issue.9 , pp. 1180-1183
    • Gorczynski, R.M.1    Lee, L.2    Boudakov, I.3
  • 138
    • 33845510301 scopus 로고    scopus 로고
    • CD200 is a new prognostic factor in multiple myeloma
    • [Comparative Study Research Support, Non-U.S. Gov't]
    • Moreaux J., Hose D., Reme T., Jourdan E., Hundemer M., Legouffe E., et al. CD200 is a new prognostic factor in multiple myeloma. Blood Dec 15 2006, 108(13):4194-4197. [Comparative Study Research Support, Non-U.S. Gov't].
    • (2006) Blood , vol.108 , Issue.13 , pp. 4194-4197
    • Moreaux, J.1    Hose, D.2    Reme, T.3    Jourdan, E.4    Hundemer, M.5    Legouffe, E.6
  • 139
    • 84863733413 scopus 로고    scopus 로고
    • Immunophenotypic stability of CD200 expression in plasma cell myeloma
    • [Comment Letter]
    • Olteanu H., Harrington A.M., Kroft S.H. Immunophenotypic stability of CD200 expression in plasma cell myeloma. Am J Clin Pathol Jun 2012, 137(6):1013-1014. [Comment Letter].
    • (2012) Am J Clin Pathol , vol.137 , Issue.6 , pp. 1013-1014
    • Olteanu, H.1    Harrington, A.M.2    Kroft, S.H.3
  • 140
    • 33750614944 scopus 로고    scopus 로고
    • Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients
    • Banerjee D.K., Dhodapkar M.V., Matayeva E., Steinman R.M., Dhodapkar K.M. Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients. Blood Oct 15 2006, 108(8):2655-2661.
    • (2006) Blood , vol.108 , Issue.8 , pp. 2655-2661
    • Banerjee, D.K.1    Dhodapkar, M.V.2    Matayeva, E.3    Steinman, R.M.4    Dhodapkar, K.M.5
  • 141
    • 80051616648 scopus 로고    scopus 로고
    • CD28 expressed on malignant plasma cells induces a prosurvival and immunosuppressive microenvironment
    • Nair J., Carlson L., Koorella C., Rozanski C., Byrne G., Bergsagel P., et al. CD28 expressed on malignant plasma cells induces a prosurvival and immunosuppressive microenvironment. J Immunol 2011, 187(3):1243-1253.
    • (2011) J Immunol , vol.187 , Issue.3 , pp. 1243-1253
    • Nair, J.1    Carlson, L.2    Koorella, C.3    Rozanski, C.4    Byrne, G.5    Bergsagel, P.6
  • 142
    • 0020673510 scopus 로고
    • Abnormal monoclonal antibody-defined helper/suppressor T-cell subpopulations in multiple myeloma: relationship to treatment and clinical stage
    • Mills K., Cawley J. Abnormal monoclonal antibody-defined helper/suppressor T-cell subpopulations in multiple myeloma: relationship to treatment and clinical stage. Br J Haematol 1983, 53(2):271-275.
    • (1983) Br J Haematol , vol.53 , Issue.2 , pp. 271-275
    • Mills, K.1    Cawley, J.2
  • 144
    • 0026540493 scopus 로고
    • Lymphoid subsets and prognostic factors in multiple myeloma. Cooperative Group for the Study of Monoclonal Gammopathies
    • San Miguel J., González M., Gascón A., Moro M., Hernández J., Ortega F., et al. Lymphoid subsets and prognostic factors in multiple myeloma. Cooperative Group for the Study of Monoclonal Gammopathies. Br J Haematol 1992, 80(3):305-309.
    • (1992) Br J Haematol , vol.80 , Issue.3 , pp. 305-309
    • San Miguel, J.1    González, M.2    Gascón, A.3    Moro, M.4    Hernández, J.5    Ortega, F.6
  • 145
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties
    • [Review]
    • Mosmann T.R., Coffman R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989, 7:145-173. [Review].
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 146
    • 0034945969 scopus 로고    scopus 로고
    • Severe and long-lasting disruption of T-cell receptor diversity in human myeloma after high-dose chemotherapy and autologous peripheral blood progenitor cell infusion
    • [Comparative Study Research Support, Non-U.S. Gov't]
    • Mariani S., Coscia M., Even J., Peola S., Foglietta M., Boccadoro M., et al. Severe and long-lasting disruption of T-cell receptor diversity in human myeloma after high-dose chemotherapy and autologous peripheral blood progenitor cell infusion. Br J Haematol Jun 2001, 113(4):1051-1059. [Comparative Study Research Support, Non-U.S. Gov't].
    • (2001) Br J Haematol , vol.113 , Issue.4 , pp. 1051-1059
    • Mariani, S.1    Coscia, M.2    Even, J.3    Peola, S.4    Foglietta, M.5    Boccadoro, M.6
  • 147
    • 0035525736 scopus 로고    scopus 로고
    • Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8(+)CD57(+)CD28(-) compartment
    • [Research Support, Non-U.S. Gov't]
    • Sze D.M., Giesajtis G., Brown R.D., Raitakari M., Gibson J., Ho J., et al. Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8(+)CD57(+)CD28(-) compartment. Blood Nov 1 2001, 98(9):2817-2827. [Research Support, Non-U.S. Gov't].
    • (2001) Blood , vol.98 , Issue.9 , pp. 2817-2827
    • Sze, D.M.1    Giesajtis, G.2    Brown, R.D.3    Raitakari, M.4    Gibson, J.5    Ho, J.6
  • 148
    • 27644457376 scopus 로고    scopus 로고
    • TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
    • [Research Support, Non-U.S. Gov't]
    • Thomas D.A., Massague J. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell Nov 2005, 8(5):369-380. [Research Support, Non-U.S. Gov't].
    • (2005) Cancer Cell , vol.8 , Issue.5 , pp. 369-380
    • Thomas, D.A.1    Massague, J.2
  • 149
    • 0842265594 scopus 로고    scopus 로고
    • Signalling molecules and cytokine production in T cells of multiple myeloma-increased abnormalities with advancing stage
    • [Research Support, Non-U.S. Gov't]
    • Mozaffari F., Hansson L., Kiaii S., Ju X., Rossmann E.D., Rabbani H., et al. Signalling molecules and cytokine production in T cells of multiple myeloma-increased abnormalities with advancing stage. Br J Haematol Feb 2004, 124(3):315-324. [Research Support, Non-U.S. Gov't].
    • (2004) Br J Haematol , vol.124 , Issue.3 , pp. 315-324
    • Mozaffari, F.1    Hansson, L.2    Kiaii, S.3    Ju, X.4    Rossmann, E.D.5    Rabbani, H.6
  • 150
    • 0028929845 scopus 로고
    • Idiotype-specific T cells in multiple myeloma stage I: an evaluation by four different functional tests
    • [Research Support, Non-U.S. Gov't]
    • Osterborg A., Yi Q., Bergenbrant S., Holm G., Lefvert A.K., Mellstedt H. Idiotype-specific T cells in multiple myeloma stage I: an evaluation by four different functional tests. Br J Haematol Jan 1995, 89(1):110-116. [Research Support, Non-U.S. Gov't].
    • (1995) Br J Haematol , vol.89 , Issue.1 , pp. 110-116
    • Osterborg, A.1    Yi, Q.2    Bergenbrant, S.3    Holm, G.4    Lefvert, A.K.5    Mellstedt, H.6
  • 151
    • 0345599884 scopus 로고    scopus 로고
    • Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Dhodapkar M.V., Krasovsky J., Osman K., Geller M.D. Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy. J Exp Med Dec 1 2003, 198(11):1753-1757. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (2003) J Exp Med , vol.198 , Issue.11 , pp. 1753-1757
    • Dhodapkar, M.V.1    Krasovsky, J.2    Osman, K.3    Geller, M.D.4
  • 152
    • 0035869383 scopus 로고    scopus 로고
    • Idiotype-specific cytotoxic T lymphocytes in multiple myeloma: evidence for their capacity to lyse autologous primary tumor cells
    • [Research Support, Non-U.S. Gov't]
    • Wen Y.J., Barlogie B., Yi Q. Idiotype-specific cytotoxic T lymphocytes in multiple myeloma: evidence for their capacity to lyse autologous primary tumor cells. Blood Mar 15 2001, 97(6):750-755. [Research Support, Non-U.S. Gov't].
    • (2001) Blood , vol.97 , Issue.6 , pp. 750-755
    • Wen, Y.J.1    Barlogie, B.2    Yi, Q.3
  • 153
    • 33745802534 scopus 로고    scopus 로고
    • Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research
    • Bogen B., Ruffini P.A., Corthay A., Fredriksen A.B., Froyland M., Lundin K., et al. Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research. Haematologica Jul 2006, 91(7):941-948.
    • (2006) Haematologica , vol.91 , Issue.7 , pp. 941-948
    • Bogen, B.1    Ruffini, P.A.2    Corthay, A.3    Fredriksen, A.B.4    Froyland, M.5    Lundin, K.6
  • 154
    • 0032100486 scopus 로고    scopus 로고
    • Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Haslett P.A., Corral L.G., Albert M., Kaplan G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset. J Exp Med Jun 1 1998, 187(11):1885-1892. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (1998) J Exp Med , vol.187 , Issue.11 , pp. 1885-1892
    • Haslett, P.A.1    Corral, L.G.2    Albert, M.3    Kaplan, G.4
  • 155
    • 0034667620 scopus 로고    scopus 로고
    • Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells
    • Li Y., Bendandi M., Deng Y., Dunbar C., Munshi N., Jagannath S., et al. Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells. Blood Oct 15 2000, 96(8):2828-2833.
    • (2000) Blood , vol.96 , Issue.8 , pp. 2828-2833
    • Li, Y.1    Bendandi, M.2    Deng, Y.3    Dunbar, C.4    Munshi, N.5    Jagannath, S.6
  • 156
    • 28844462429 scopus 로고    scopus 로고
    • CD8+ T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden
    • [Research Support, Non-U.S. Gov't]
    • Goodyear O., Piper K., Khan N., Starczynski J., Mahendra P., Pratt G., et al. CD8+ T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden. Blood Dec 15 2005, 106(13):4217-4224. [Research Support, Non-U.S. Gov't].
    • (2005) Blood , vol.106 , Issue.13 , pp. 4217-4224
    • Goodyear, O.1    Piper, K.2    Khan, N.3    Starczynski, J.4    Mahendra, P.5    Pratt, G.6
  • 157
    • 20144383847 scopus 로고    scopus 로고
    • Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma
    • Choi C., Witzens M., Bucur M., Feuerer M., Sommerfeldt N., Trojan A., et al. Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma. Blood Mar 1 2005, 105(5):2132-2134.
    • (2005) Blood , vol.105 , Issue.5 , pp. 2132-2134
    • Choi, C.1    Witzens, M.2    Bucur, M.3    Feuerer, M.4    Sommerfeldt, N.5    Trojan, A.6
  • 158
    • 34247339604 scopus 로고    scopus 로고
    • Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy
    • [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
    • Spisek R., Kukreja A., Chen L.C., Matthews P., Mazumder A., Vesole D., et al. Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy. J Exp Med Apr 16 2007, 204(4):831-840. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't].
    • (2007) J Exp Med , vol.204 , Issue.4 , pp. 831-840
    • Spisek, R.1    Kukreja, A.2    Chen, L.C.3    Matthews, P.4    Mazumder, A.5    Vesole, D.6
  • 159
    • 33646575622 scopus 로고    scopus 로고
    • In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma
    • Beyer M., Kochanek M., Giese T., Endl E., Weihrauch M.R., Knolle P.A., et al. In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma. Blood May 15 2006, 107(10):3940-3949.
    • (2006) Blood , vol.107 , Issue.10 , pp. 3940-3949
    • Beyer, M.1    Kochanek, M.2    Giese, T.3    Endl, E.4    Weihrauch, M.R.5    Knolle, P.A.6
  • 160
    • 58849093606 scopus 로고    scopus 로고
    • CD4(+)CD25(+)FoxP3(+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-)alphabetaTCR(+) double negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden
    • [Comparative Study Research Support, Non-U.S. Gov't]
    • Feyler S., von Lilienfeld-Toal M., Jarmin S., Marles L., Rawstron A., Ashcroft A.J., et al. CD4(+)CD25(+)FoxP3(+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-)alphabetaTCR(+) double negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden. Br J Haematol Mar 2009, 144(5):686-695. [Comparative Study Research Support, Non-U.S. Gov't].
    • (2009) Br J Haematol , vol.144 , Issue.5 , pp. 686-695
    • Feyler, S.1    von Lilienfeld-Toal, M.2    Jarmin, S.3    Marles, L.4    Rawstron, A.5    Ashcroft, A.J.6
  • 161
    • 20244386558 scopus 로고    scopus 로고
    • Exposure to myeloma cell lysates affects the immune competence of dendritic cells and favors the induction of Tr1-like regulatory T cells
    • Fiore F., Nuschak B., Peola S., Mariani S., Muraro M., Foglietta M., et al. Exposure to myeloma cell lysates affects the immune competence of dendritic cells and favors the induction of Tr1-like regulatory T cells. Eur J Immunol Apr 2005, 35(4):1155-1163.
    • (2005) Eur J Immunol , vol.35 , Issue.4 , pp. 1155-1163
    • Fiore, F.1    Nuschak, B.2    Peola, S.3    Mariani, S.4    Muraro, M.5    Foglietta, M.6
  • 162
    • 40849141379 scopus 로고    scopus 로고
    • CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation
    • Atanackovic D., Cao Y., Luetkens T., Panse J., Faltz C., Arfsten J., et al. CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation. Haematologica 2008, 93(3):423-430.
    • (2008) Haematologica , vol.93 , Issue.3 , pp. 423-430
    • Atanackovic, D.1    Cao, Y.2    Luetkens, T.3    Panse, J.4    Faltz, C.5    Arfsten, J.6
  • 163
    • 0042591467 scopus 로고    scopus 로고
    • Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Mellor A.L., Baban B., Chandler P., Marshall B., Jhaver K., Hansen A., et al. Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J Immunol Aug 15 2003, 171(4):1652-1655. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (2003) J Immunol , vol.171 , Issue.4 , pp. 1652-1655
    • Mellor, A.L.1    Baban, B.2    Chandler, P.3    Marshall, B.4    Jhaver, K.5    Hansen, A.6
  • 164
    • 34547098277 scopus 로고    scopus 로고
    • Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression
    • [Research Support, Non-U.S. Gov't]
    • Borsellino G., Kleinewietfeld M., Di Mitri D., Sternjak A., Diamantini A., Giometto R., et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood Aug 15 2007, 110(4):1225-1232. [Research Support, Non-U.S. Gov't].
    • (2007) Blood , vol.110 , Issue.4 , pp. 1225-1232
    • Borsellino, G.1    Kleinewietfeld, M.2    Di Mitri, D.3    Sternjak, A.4    Diamantini, A.5    Giometto, R.6
  • 165
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • [Research Support, U.S. Gov't, P.H.S. Review]
    • von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol Apr 2005, 6(4):338-344. [Research Support, U.S. Gov't, P.H.S. Review].
    • (2005) Nat Immunol , vol.6 , Issue.4 , pp. 338-344
    • von Boehmer, H.1
  • 166
    • 84861538114 scopus 로고    scopus 로고
    • Tumour cell generation of inducible regulatory T-cells in multiple myeloma is contact-dependent and antigen-presenting cell-independent
    • Feyler S., Scott G.B., Parrish C., Jarmin S., Evans P., Short M., et al. Tumour cell generation of inducible regulatory T-cells in multiple myeloma is contact-dependent and antigen-presenting cell-independent. PLoS One 2012, 7(5):e35981.
    • (2012) PLoS One , vol.7 , Issue.5
    • Feyler, S.1    Scott, G.B.2    Parrish, C.3    Jarmin, S.4    Evans, P.5    Short, M.6
  • 167
    • 84866156002 scopus 로고    scopus 로고
    • CD86+ or HLA-G+ myeloma cells are associated with poor prognosis and once acquired by trogocytosis create novel Tregacq cells
    • Brown R., Kabani K., Favaloro J., Yang S., Ho P.J., Gibson J., et al. CD86+ or HLA-G+ myeloma cells are associated with poor prognosis and once acquired by trogocytosis create novel Tregacq cells. Blood Jun 15 2012, 120(10):2055-2063.
    • (2012) Blood , vol.120 , Issue.10 , pp. 2055-2063
    • Brown, R.1    Kabani, K.2    Favaloro, J.3    Yang, S.4    Ho, P.J.5    Gibson, J.6
  • 168
    • 33646869754 scopus 로고    scopus 로고
    • Functional regulatory T cells are collected in stem cell autografts by mobilization with high-dose cyclophosphamide and granulocyte colony-stimulating factor
    • Condomines M., Quittet P., Lu Z.Y., Nadal L., Latry P., Lopez E., et al. Functional regulatory T cells are collected in stem cell autografts by mobilization with high-dose cyclophosphamide and granulocyte colony-stimulating factor. J Immunol Jun 1 2006, 176(11):6631-6639.
    • (2006) J Immunol , vol.176 , Issue.11 , pp. 6631-6639
    • Condomines, M.1    Quittet, P.2    Lu, Z.Y.3    Nadal, L.4    Latry, P.5    Lopez, E.6
  • 169
    • 40849141379 scopus 로고    scopus 로고
    • CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation
    • Atanackovic D., Cao Y., Luetkens T., Panse J., Faltz C., Arfsten J., et al. CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation. Haematologica Mar 2008, 93(3):423-430.
    • (2008) Haematologica , vol.93 , Issue.3 , pp. 423-430
    • Atanackovic, D.1    Cao, Y.2    Luetkens, T.3    Panse, J.4    Faltz, C.5    Arfsten, J.6
  • 170
    • 59549087977 scopus 로고    scopus 로고
    • In pursuit of the allo-immune response in multiple myeloma: where do we go from here?
    • Cook G., Bird J.M., Marks D.I. In pursuit of the allo-immune response in multiple myeloma: where do we go from here?. Bone Marrow Transplant Jan 2009, 43(2):91-99.
    • (2009) Bone Marrow Transplant , vol.43 , Issue.2 , pp. 91-99
    • Cook, G.1    Bird, J.M.2    Marks, D.I.3
  • 171
    • 78751510278 scopus 로고    scopus 로고
    • Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma
    • [Clinical Trial, Phase I Research Support, N.I.H., Extramural]
    • Rosenblatt J., Vasir B., Uhl L., Blotta S., Macnamara C., Somaiya P., et al. Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma. Blood Jan 13 2011, 117(2):393-402. [Clinical Trial, Phase I Research Support, N.I.H., Extramural].
    • (2011) Blood , vol.117 , Issue.2 , pp. 393-402
    • Rosenblatt, J.1    Vasir, B.2    Uhl, L.3    Blotta, S.4    Macnamara, C.5    Somaiya, P.6
  • 172
    • 30744454570 scopus 로고    scopus 로고
    • Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer
    • [Clinical Trial, Phase I Clinical Trial, Phase II Comparative Study Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
    • Rapoport A.P., Stadtmauer E.A., Aqui N., Badros A., Cotte J., Chrisley L., et al. Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer. Nat Med Nov 2005, 11(11):1230-1237. [Clinical Trial, Phase I Clinical Trial, Phase II Comparative Study Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't].
    • (2005) Nat Med , vol.11 , Issue.11 , pp. 1230-1237
    • Rapoport, A.P.1    Stadtmauer, E.A.2    Aqui, N.3    Badros, A.4    Cotte, J.5    Chrisley, L.6
  • 173
    • 84867656722 scopus 로고    scopus 로고
    • Depletion of regulatory T lymphocytes reverses the imbalance between pro- and anti-tumor immunities via enhancing antigen-specific T cell immune responses
    • [Research Support, Non-U.S. Gov't]
    • Chen Y.L., Chang M.C., Chen C.A., Lin H.W., Cheng W.F., Chien C.L. Depletion of regulatory T lymphocytes reverses the imbalance between pro- and anti-tumor immunities via enhancing antigen-specific T cell immune responses. PLoS One 2012, 7(10):e47190. [Research Support, Non-U.S. Gov't].
    • (2012) PLoS One , vol.7 , Issue.10
    • Chen, Y.L.1    Chang, M.C.2    Chen, C.A.3    Lin, H.W.4    Cheng, W.F.5    Chien, C.L.6
  • 174
    • 84856540469 scopus 로고    scopus 로고
    • Upfront denileukin diftitox as in vivo regulatory T-cell depletion in order to enhance vaccination effects in a canine allogeneic hematopoietic stem cell transplantation model
    • [Research Support, Non-U.S. Gov't]
    • Knueppel A., Lange S., Altmann S., Sekora A., Knuebel G., Vogel H., et al. Upfront denileukin diftitox as in vivo regulatory T-cell depletion in order to enhance vaccination effects in a canine allogeneic hematopoietic stem cell transplantation model. Vet Immunol Immunopathol Jan 15 2012, 145(1-2):233-240. [Research Support, Non-U.S. Gov't].
    • (2012) Vet Immunol Immunopathol , vol.145 , Issue.1-2 , pp. 233-240
    • Knueppel, A.1    Lange, S.2    Altmann, S.3    Sekora, A.4    Knuebel, G.5    Vogel, H.6
  • 175
    • 84868555330 scopus 로고    scopus 로고
    • Depletion of T regulatory cells through selection of CD127-positive cells results in a population enriched in memory T cells: implications for anti-tumor cell therapy
    • [Research Support, Non-U.S. Gov't]
    • Touil S., Rosenzwajg M., Landau D.A., Le Corvoisier P., Frederic C., Klatzmann D., et al. Depletion of T regulatory cells through selection of CD127-positive cells results in a population enriched in memory T cells: implications for anti-tumor cell therapy. Haematologica Nov 2012, 97(11):1678-1685. [Research Support, Non-U.S. Gov't].
    • (2012) Haematologica , vol.97 , Issue.11 , pp. 1678-1685
    • Touil, S.1    Rosenzwajg, M.2    Landau, D.A.3    Le Corvoisier, P.4    Frederic, C.5    Klatzmann, D.6
  • 176
    • 84872130879 scopus 로고    scopus 로고
    • Transient Foxp3(+) regulatory T-cell depletion enhances therapeutic anticancer vaccination targeting the immune-stimulatory properties of NKT cells
    • Mattarollo S.R., Steegh K., Li M., Duret H., Foong Ngiow S., Smyth M.J. Transient Foxp3(+) regulatory T-cell depletion enhances therapeutic anticancer vaccination targeting the immune-stimulatory properties of NKT cells. Immunol Cell Biol Jan 2013, 91(1):105-114.
    • (2013) Immunol Cell Biol , vol.91 , Issue.1 , pp. 105-114
    • Mattarollo, S.R.1    Steegh, K.2    Li, M.3    Duret, H.4    Foong Ngiow, S.5    Smyth, M.J.6
  • 177
    • 84863919927 scopus 로고    scopus 로고
    • Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma
    • [Clinical Trial, Phase I Research Support, Non-U.S. Gov't
    • Lonial S., Vij R., Harousseau J.L., Facon T., Moreau P., Mazumder A., et al. Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma. J Clin Oncol Jun 1 2012, 30(16):1953-1959. [Clinical Trial, Phase I Research Support, Non-U.S. Gov't.
    • (2012) J Clin Oncol , vol.30 , Issue.16 , pp. 1953-1959
    • Lonial, S.1    Vij, R.2    Harousseau, J.L.3    Facon, T.4    Moreau, P.5    Mazumder, A.6
  • 179
    • 0033840388 scopus 로고    scopus 로고
    • A single oral dose of thalidomide enhances the capacity of lymphocytes to secrete gamma interferon in healthy humans
    • [Clinical Trial Research Support, Non-U.S. Gov't]
    • Verbon A., Juffermans N.P., Speelman P., van Deventer S.J., ten Berge I.J., Guchelaar H.J., et al. A single oral dose of thalidomide enhances the capacity of lymphocytes to secrete gamma interferon in healthy humans. Antimicrob Agents Chemother Sep 2000, 44(9):2286-2290. [Clinical Trial Research Support, Non-U.S. Gov't].
    • (2000) Antimicrob Agents Chemother , vol.44 , Issue.9 , pp. 2286-2290
    • Verbon, A.1    Juffermans, N.P.2    Speelman, P.3    van Deventer, S.J.4    ten Berge, I.J.5    Guchelaar, H.J.6
  • 180
    • 0035412366 scopus 로고    scopus 로고
    • Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
    • Davies F., Raje N., Hideshima T., Lentzsch S., Young G., Tai Y., et al. Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma. Blood 2001, 98(1):210-216.
    • (2001) Blood , vol.98 , Issue.1 , pp. 210-216
    • Davies, F.1    Raje, N.2    Hideshima, T.3    Lentzsch, S.4    Young, G.5    Tai, Y.6
  • 181
    • 0036381106 scopus 로고    scopus 로고
    • Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells
    • Marriott J., Clarke I., Dredge K., Muller G., Stirling D., Dalgleish A. Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells. Clin Exp Immunol 2002, 130(1):75-84.
    • (2002) Clin Exp Immunol , vol.130 , Issue.1 , pp. 75-84
    • Marriott, J.1    Clarke, I.2    Dredge, K.3    Muller, G.4    Stirling, D.5    Dalgleish, A.6
  • 182
    • 10744231369 scopus 로고    scopus 로고
    • Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.]
    • LeBlanc R., Hideshima T., Catley L.P., Shringarpure R., Burger R., Mitsiades N., et al. Immunomodulatory drug costimulates T cells via the B7-CD28 pathway. Blood Mar 1 2004, 103(5):1787-1790. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.].
    • (2004) Blood , vol.103 , Issue.5 , pp. 1787-1790
    • LeBlanc, R.1    Hideshima, T.2    Catley, L.P.3    Shringarpure, R.4    Burger, R.5    Mitsiades, N.6
  • 183
    • 19944430437 scopus 로고    scopus 로고
    • Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application
    • [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
    • Hayashi T., Hideshima T., Akiyama M., Podar K., Yasui H., Raje N., et al. Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application. Br J Haematol Jan 2005, 128(2):192-203. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.].
    • (2005) Br J Haematol , vol.128 , Issue.2 , pp. 192-203
    • Hayashi, T.1    Hideshima, T.2    Akiyama, M.3    Podar, K.4    Yasui, H.5    Raje, N.6
  • 184
    • 33745961875 scopus 로고    scopus 로고
    • Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implications
    • [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
    • Chang D.H., Liu N., Klimek V., Hassoun H., Mazumder A., Nimer S.D., et al. Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implications. Blood Jul 15 2006, 108(2):618-621. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't].
    • (2006) Blood , vol.108 , Issue.2 , pp. 618-621
    • Chang, D.H.1    Liu, N.2    Klimek, V.3    Hassoun, H.4    Mazumder, A.5    Nimer, S.D.6
  • 185
    • 84872481628 scopus 로고    scopus 로고
    • Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma
    • Richter J., Neparidze N., Zhang L., Nair S., Monesmith T., Sundaram R., et al. Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma. Blood 2013 Jan 17, 121(3):423-430.
    • (2013) Blood , vol.121 , Issue.3 , pp. 423-430
    • Richter, J.1    Neparidze, N.2    Zhang, L.3    Nair, S.4    Monesmith, T.5    Sundaram, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.