Consequences of double negative regulatory T cell and antigen presenting cell interaction on immune response suppression

International Immunopharmacology

Volumn 11, Issue 5, 2011, Pages 597-603

  Ford McIntyre, Megan S ^a   Gao, Julia Fang ^a,b   Li, Xujian ^a   Naeini, Bardya M ^a   Zhang, Li ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Antigen presenting cells; B cells; Double negative regulatory T cells

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; LIPOPOLYSACCHARIDE; LYMPHOCYTE ANTIGEN; NK1.1 ANTIGEN; PERFORIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL INTERACTION; CELL TYPE; CONTROLLED STUDY; EFFECTOR CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD; B-LYMPHOCYTES; CELL COMMUNICATION; CELL PROLIFERATION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; IMMUNE TOLERANCE; ISOANTIGENS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; MICE, MUTANT STRAINS; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 79954630416     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.11.015     Document Type: Article

References (42)

1. S. Jung, D. Unutmaz, P. Wong, G. Sano, S.K. De los, Sparwasser T., and Wu S. In vivo depletion of CD11c + dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens Immunity 17 2002 211 220 (Pubitemid 35245963)
2. H.C. Probst, and B.M. van den Priming of CTLs by lymphocytic choriomeningitis virus depends on dendritic cells J Immunol 174 2005 3920 3924 (Pubitemid 40395965)
3. K. Hochweller, and S.M. Anderton Kinetics of costimulatory molecule expression by T cells and dendritic cells during the induction of tolerance versus immunity in vivo Eur J Immunol 35 2005 1086 1096 (Pubitemid 40542215)
4. S.H. Rhee, and D. Hwang Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase J Biol Chem 275 2000 34035 34040
5. A. Poltorak, X. He, I. Smirnova, M.Y. Liu, H.C. Van, and X. Du Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 282 1998 2085 2088 (Pubitemid 29001265)
6. T. Mattern, A. Thanhauser, N. Reiling, K.M. Toellner, M. Duchrow, and S. Kusumoto Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes J Immunol 153 1994 2996 3004 (Pubitemid 24292525)
7. Z. Razi-Wolf, G.J. Freeman, F. Galvin, B. Benacerraf, L. Nadler, and H. Reiser Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells Proc Natl Acad Sci U S A 89 1992 4210 4214
8. U. Kyan-Aung, D.O. Haskard, R.N. Poston, M.H. Thornhill, and T.H. Lee Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo J Immunol 146 1991 521 528
9. G. Siu, S.M. Hedrick, and A.A. Brian Isolation of the murine intercellular adhesion molecule 1 (ICAM-1) gene. ICAM-1 enhances antigen-specific T cell activation J Immunol 143 1989 3813 3820 (Pubitemid 20007059)
10. D.L. Peavy, W.H. Adler, and R.T. Smith The mitogenic effects of endotoxin and staphylococcal enterotoxin B on mouse spleen cells and human peripheral lymphocytes J Immunol 105 1970 1453 1458
11. Z. Fehervari, and S. Sakaguchi Control of Foxp3+ CD25+ CD4+ regulatory cell activation and function by dendritic cells Int Immunol 16 2004 1769 1780 (Pubitemid 40003865)
12. E.A. Moseman, X. Liang, A.J. Dawson, A. Panoskaltsis-Mortari, A.M. Krieg, and Y.J. Liu Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+ CD25+ regulatory T cells J Immunol 173 2004 4433 4442 (Pubitemid 39280673)
13. R.M. Gorczynski Thymocyte/splenocyte-derived CD4+ CD25+ Treg stimulated by anti-CD200R2 derived dendritic cells suppress mixed leukocyte cultures and skin graft rejection Transplantation 81 2006 1027 1034 (Pubitemid 43670437)
14. L.C. Chen, J.C. Delgado, P.E. Jensen, and X. Chen Direct expansion of human allospecific FoxP3+ CD4+ regulatory T cells with allogeneic B cells for therapeutic application J Immunol 183 2009 4094 4102
15. W. Tu, Y.L. Lau, J. Zheng, Y. Liu, P.L. Chan, and H. Mao Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naïve precursors by CD40-activated B cells Blood 112 2008 2554 2562
16. X. Chen, and P.E. Jensen Cutting edge: primary B lymphocytes preferentially expand allogeneic FoxP3+ CD4 T cells J Immunol 179 2007 2046 2050
17. R. Houot, I. Perrot, E. Garcia, I. Durand, and S. Lebecque Human CD4+ CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation J Immunol 176 2006 5293 5298
18. M.L. Fields, B.D. Hondowicz, M.H. Metzgar, S.A. Nish, G.N. Wharton, and C.C. Picca CD4+ CD25+ regulatory T cells inhibit the maturation but not the initiation of an autoantibody response J Immunol 175 2005 4255 4264 (Pubitemid 41361959)
19. L.S. Taams, J.M. van Amelsfort, M.M. Tiemessen, K.M. Jacobs, E.C. de Jong, and A.N. Akbar Modulation of monocyte/macrophage function by human CD4+ CD25+ regulatory T cells Hum Immunol 66 2005 222 230 (Pubitemid 40395242)
20. N. Misra, J. Bayry, S. Lacroix-Desmazes, M.D. Kazatchkine, and S.V. Kaveri Cutting edge: human CD4+ CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells J Immunol 172 2004 4676 4680 (Pubitemid 38456386)
21. L. Cederbom, H. Hall, and F. Ivars CD4 + CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells Eur J Immunol 30 2000 1538 1543 (Pubitemid 30342794)
22. K. Fischer, S. Voelkl, J. Heymann, G.K. Przybylski, K. Mondal, and M. Laumer Isolation and characterization of human antigen-specific TCR alpha beta + CD4(-)CD8- double-negative regulatory T cells Blood 105 2005 2828 2835 (Pubitemid 40446276)
23. Z.X. Zhang, L. Yang, K.J. Young, B. DuTemple, and L. Zhang Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression Nat Med 6 2000 782 789 (Pubitemid 30469427)
24. M.S. Ford, K.J. Young, Z. Zhang, P.S. Ohashi, and L. Zhang The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo J Exp Med 196 2002 261 267 (Pubitemid 34787516)
25. K.J. Young, and L. Zhang The nature and mechanisms of DN regulatory T-cell mediated suppression Hum Immunol 63 2002 926 934 (Pubitemid 35246773)
26. T. Kubo, R.D. Hatton, J. Oliver, X. Liu, C.O. Elson, and C.T. Weaver Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells J Immunol 173 2004 7249 7258 (Pubitemid 39628161)
27. G. Raimondi, I. Zanoni, S. Citterio, P. Ricciardi-Castagnoli, and F. Granucci Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence J Immunol 176 2006 4012 4020 (Pubitemid 44264379)
28. S. Fillatreau, C.H. Sweenie, M.J. McGeachy, D. Gray, and S.M. Anderton B cells regulate autoimmunity by provision of IL-10 Nat Immunol 3 2002 944 950 (Pubitemid 35154008)
29. E.E. Eynon, and D.C. Parker Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens J Exp Med 175 1992 131 138
30. E.J. Fuchs, and P. Matzinger B cells turn off virgin but not memory T cells Science 258 1992 1156 1159
31. B.P. Lee, W. Chen, H. Shi, S.D. Der, R. Forster, and L. Zhang CXCR5/CXCL13 interaction is important for double-negative regulatory T cell homing to cardiac allografts J Immunol 176 2006 5276 5283
32. T. Kadena, G. Matsuzaki, S. Fujise, K. Kishihara, H. Takimoto, and M. Sasaki TCR alpha beta + CD4- CD8- T cells differentiate extrathymically in an lck-independent manner and participate in early response against Listeria monocytogenes infection through interferon-gamma production Immunology 91 1997 511 519 (Pubitemid 27312331)
33. M.S. Hossain, H. Takimoto, T. Ninomiya, H. Yoshida, K. Kishihara, and G. Matsuzaki Characterization of CD4- CD8- CD3+ T-cell receptor-alphabeta + T cells in murine cytomegalovirus infection Immunology 101 2000 19 29
34. M. Johansson, and N. Lycke A unique population of extrathymically derived alpha beta TCR + CD4- CD8- T cells with regulatory functions dominates the mouse female genital tract J Immunol 170 2003 1659 1666 (Pubitemid 36197379)
35. N.D. Mathiot, R. Krueger, M.A. French, and P. Price Percentage of CD3+ CD4- CD8- gammadeltaTCR- T cells is increased HIV disease AIDS Res Hum Retroviruses 17 2001 977 980
36. J.F. Moreau, J.L. Taupin, M. Dupon, J.C. Carron, J.M. Ragnaud, and C. Marimoutou Increases in CD3+ CD4- CD8- T lymphocytes in AIDS patients with disseminated Mycobacterium avium-intracellulare complex infection J Infect Dis 174 1996 969 976 (Pubitemid 26357458)
37. G. Carulli, G. Lagomarsini, A. Azzara, R. Testi, R. Riccioni, and M. Petrini Expansion of TcRalphabeta + CD3 + CD4- CD8- (CD4/CD8 double-negative) T lymphocytes in a case of staphylococcal toxic shock syndrome Acta Haematol 111 2004 163 167 (Pubitemid 38437669)
38. S.C. Cowley, E. Hamilton, J.A. Frelinger, J. Su, J. Forman, and K.L. Elkins CD4- CD8- T cells control intracellular bacterial infections both in vitro and in vivo J Exp Med 202 2005 309 319 (Pubitemid 41043826)
39. W. Chen, J. Diao, S.M. Stepkowski, and L. Zhang Both infiltrating regulatory T cells and insufficient antigen presentation are involved in long-term cardiac xenograft survival J Immunol 179 2007 1542 1548
40. K. Wing, Y. Onishi, P. Prieto-Martin, T. Yamaguchi, M. Miyara, and Z. Fehervari CTLA-4 control over Foxp3+ regulatory T cell function Science 322 2008 271 275
41. Hillhouse E.E., Beauchamp C., Chabot-Roy G., Dugas V., and Lesage S. Interleukin-10 limits the expansion of immunoregulatory CD4(-)CD8(-) T cells in autoimmune-prone non-obese diabetic mice Immunol Cell Biol 2010
42. Z.X. Zhang, Y. Ma, H. Wang, J. Arp, J. Jiang, and X. Huang Double-negative T cells, activated by xenoantigen, lyse autologous B and T cells using a perforin/granzyme-dependent, Fas-Fas ligand-independent pathway J Immunol 177 2006 6920 6929 (Pubitemid 44715058)