-
1
-
-
0034008242
-
Systemic enzyme therapy in oncology: Effect and mode of action
-
Leipner J, Saller R. Systemic enzyme therapy in oncology: effect and mode of action. Drugs 2000;59:769-780. (Pubitemid 30232319)
-
(2000)
Drugs
, vol.59
, Issue.4
, pp. 769-780
-
-
Leipner, J.1
Saller, R.2
-
2
-
-
58149195294
-
Proteolytic enzyme therapy in evidence-based complementary oncology: Fact or fiction
-
Beuth J. Proteolytic enzyme therapy in evidence-based complementary oncology: fact or fiction Integr Cancer Ther 2008;7:311-316.
-
(2008)
Integr Cancer Ther
, vol.7
, pp. 311-316
-
-
Beuth, J.1
-
3
-
-
33845889257
-
Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: A randomized placebo-controlled pilot study
-
DOI 10.1093/qjmed/hcl118
-
Brien S, Lewith G, Walker AF, Middleton R, Prescott P, Bundy R. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-850. (Pubitemid 46024095)
-
(2006)
QJM
, vol.99
, Issue.12
, pp. 841-850
-
-
Brien, S.1
Lewith, G.2
Walker, A.F.3
Middleton, R.4
Prescott, P.5
Bundy, R.6
-
4
-
-
33645061272
-
Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip.A double-blind, randomised study comparing oral enzymes with non-steroidal anti-inflammatory drugs
-
Klein G, KullichW, Schnitker J, Schwann H. Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A double-blind, randomised study comparing oral enzymes with non-steroidal anti-inflammatory drugs. Clin Exp Rheumatol 2006;24:25-30.
-
(2006)
Clin Exp Rheumatol
, vol.24
, pp. 25-30
-
-
Klein, G.1
Kullich, W.2
Schnitker, J.3
Schwann, H.4
-
5
-
-
0036526826
-
Efficacy and safety of phlogenzym-A protease formulation, in sepsis in children
-
Shahid SK, Turakhia NH, Kundra M, Shanbag P, Daftary GV, Schiess W. Efficacy and safety of phlogenzym-a protease formulation, in sepsis in children. J Assoc Physicians India 2002;50:527-531.
-
(2002)
J Assoc Physicians India
, vol.50
, pp. 527-531
-
-
Shahid, S.K.1
Turakhia, N.H.2
Kundra, M.3
Shanbag, P.4
Daftary, G.V.5
Schiess, W.6
-
6
-
-
0034843751
-
Bromelain: Biochemistry, pharmacology and medical use
-
Maurer HR. Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci 2001;58:1234-1245. (Pubitemid 32850918)
-
(2001)
Cellular and Molecular Life Sciences
, vol.58
, Issue.9
, pp. 1234-1245
-
-
Maurer, H.R.1
-
7
-
-
0033227511
-
Effects of oral bromelain administration on the impaired immunocytotoxicity of mononuclear cells from mammary tumor patients
-
Eckert K, Grabowska E, Stange R, Schneider U, Eschmann K, Maurer HR. Effects of oral bromelain administration on the impaired immunocytotoxicity of mononuclear cells from mammary tumor patients. Oncol Rep 1999;6:1191-1199.
-
(1999)
Oncol Rep
, vol.6
, pp. 1191-1199
-
-
Eckert, K.1
Grabowska, E.2
Stange, R.3
Schneider, U.4
Eschmann, K.5
Maurer, H.R.6
-
8
-
-
0022353891
-
Inhibition of tumour growth in vitro by bromelain, an extract of the pineapple plant (Ananas comosus)
-
Taussig SJ, Szekerczes J, Batkin S. Inhibition of tumour growth in vitro by bromelain, an extract of the pineapple plant (Ananas comosus). Planta Med 1985;51:538-539. (Pubitemid 16176666)
-
(1985)
Planta Medica
, vol.NO. 6
, pp. 538-539
-
-
Taussig, S.J.1
Szekerczes, J.2
Batkin, S.3
-
9
-
-
67649968417
-
Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NFkappa B against skin tumor-initiation triggering mitochondrial death pathway
-
Bhui K, Prasad S, George J, Shukla Y. Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NFkappa B against skin tumor-initiation triggering mitochondrial death pathway. Cancer Lett 2009;282:167-176.
-
(2009)
Cancer Lett
, vol.282
, pp. 167-176
-
-
Bhui, K.1
Prasad, S.2
George, J.3
Shukla, Y.4
-
10
-
-
78650078659
-
Pineapple bromelain induces autophagy, facilitating apoptotic response in mammary carcinoma cells
-
Bhui K, Tyagi S, Prakash B, Shukla Y. Pineapple bromelain induces autophagy, facilitating apoptotic response in mammary carcinoma cells. Biofactors 2010;36:474-482.
-
(2010)
Biofactors
, vol.36
, pp. 474-482
-
-
Bhui, K.1
Tyagi, S.2
Prakash, B.3
Shukla, Y.4
-
11
-
-
39149095242
-
Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro
-
Onken JE, Greer PK, Calingaert B, Hale LP. Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro. Clin Immunol 2008;126:345-352.
-
(2008)
Clin Immunol
, vol.126
, pp. 345-352
-
-
Onken, J.E.1
Greer, P.K.2
Calingaert, B.3
Hale, L.P.4
-
12
-
-
84855853564
-
Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 andmelanoma A375 cells through G(2)/M arrest to apoptosis
-
Bhui K, Tyagi S, Srivastava AK, Singh M, Roy P, Singh R, Shukla Y. Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 andmelanoma A375 cells through G(2)/M arrest to apoptosis. Mol Carcinog 2012;51:231-243.
-
(2012)
Mol Carcinog
, vol.51
, pp. 231-243
-
-
Bhui, K.1
Tyagi, S.2
Srivastava, A.K.3
Singh, M.4
Roy, P.5
Singh, R.6
Shukla, Y.7
-
13
-
-
36048972997
-
In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain
-
DOI 10.1055/s-2007-990221
-
Baez R, Lopes MT, Salas CE, Hernandez M. In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain. Planta Med 2007;73:1377-1383. (Pubitemid 350084456)
-
(2007)
Planta Medica
, vol.73
, Issue.13
, pp. 1377-1383
-
-
Beez, R.1
Lopes, M.T.P.2
Salas, C.E.3
Hernandez, M.4
-
14
-
-
0036972429
-
Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults
-
DOI 10.1078/094471102321621269
-
Walker AF, Bundy R, Hicks SM, Middleton RW. Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults. Phytomedicine 2002;9:681-686. (Pubitemid 36152125)
-
(2002)
Phytomedicine
, vol.9
, Issue.8
, pp. 681-686
-
-
Walker, A.F.1
Bundy, R.2
Hicks, S.M.3
Middleton, R.W.4
-
15
-
-
0029913698
-
Drug therapy of activated arthrosis: On the effectiveness of an enzyme mixture versus diclofenac
-
Singer F, Oberleitner H. Drug therapy of activated arthrosis: on the effectiveness of an enzyme mixture versus diclofenac. Wien MedWochenschr 1996;146:55-58.
-
(1996)
Wien MedWochenschr
, vol.146
, pp. 55-58
-
-
Singer, F.1
Oberleitner, H.2
-
16
-
-
0024268463
-
Validation study of WOMAC: A health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee
-
Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988;15:1833-1840. (Pubitemid 19037656)
-
(1988)
Journal of Rheumatology
, vol.15
, Issue.12
, pp. 1833-1840
-
-
Bellamy, N.1
Buchanan, W.W.2
Goldsmith, C.H.3
Campbell, J.4
Stitt, L.W.5
-
17
-
-
0027484026
-
Controlled clinical studies of nimesulide in the treatment of urogenital inflammation
-
Lotti T, Mirone V, Imbimbo C, Corrado F, Corrado G, Garofalo F, Scaricabarozzi I. Controlled clinical studies of nimesulide in the treatment of urogenital inflammation. Drugs 1993;46 (Suppl. 1):144-146. (Pubitemid 23324635)
-
(1993)
Drugs
, vol.46
, Issue.SUPPL.1
, pp. 144-146
-
-
Lotti, T.1
Mirone, V.2
Imbimbo, C.3
Corrado, F.4
Corrado, G.5
Garofalo, F.6
Scaricabarozzi, I.7
-
18
-
-
33748986863
-
Herbal medicines for the treatment of rhinosinusitis: A systematic review
-
DOI 10.1016/j.otohns.2006.06.1254, PII S0194599806026684
-
GuoR, Canter PH,Ernst E.Herbalmedicines for the treatment of rhinosinusitis: a systematic review. Otolaryngol Head Neck Surg 2006;135:496-506. (Pubitemid 44441648)
-
(2006)
Otolaryngology - Head and Neck Surgery
, vol.135
, Issue.4
, pp. 496-506
-
-
Guo, R.1
Canter, P.H.2
Ernst, E.3
-
20
-
-
33947687854
-
Inflammation in prostate carcinogenesis
-
DOI 10.1038/nrc2090, PII NRC2090
-
De Marzo AM, Platz EA, Sutcliffe S, Xu J, Gronberg H, Drake CG, Nakai Y, Isaacs WB, Nelson WG. Inflammation in prostate carcinogenesis. Nat Rev Cancer 2007;7:256-269. (Pubitemid 46486616)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.4
, pp. 256-269
-
-
De Marzo, A.M.1
Platz, E.A.2
Sutcliffe, S.3
Xu, J.4
Gronberg, H.5
Drake, C.G.6
Nakai, Y.7
Isaacs, W.B.8
Nelson, W.G.9
-
21
-
-
34447120115
-
Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy
-
DOI 10.2174/138955707780859431
-
Sarkar FH, Adsule S, Li Y, Padhye S. Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy. Mini Rev Med Chem 2007;7:599-608. (Pubitemid 47099180)
-
(2007)
Mini-Reviews in Medicinal Chemistry
, vol.7
, Issue.6
, pp. 599-608
-
-
Sarkar, F.H.1
Adsule, S.2
Li, Y.3
Padhye, S.4
-
22
-
-
32544442362
-
COX inhibitors and breast cancer
-
DOI 10.1038/sj.bjc.6602942, PII 6602942
-
Mazhar D, Ang R,Waxman J. COX inhibitors and breast cancer. Br J Cancer 2006;94:346-350. (Pubitemid 43237558)
-
(2006)
British Journal of Cancer
, vol.94
, Issue.3
, pp. 346-350
-
-
Mazhar, D.1
Ang, R.2
Waxman, J.3
-
23
-
-
36849030829
-
Regulation of p53, nuclear factor κB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin
-
DOI 10.1016/j.taap.2007.08.012, PII S0041008X07003754
-
Kalra N, Bhui K, Roy P, Srivastava S, George J, Prasad S, Shukla Y Regulation of p53, nuclear factor kappaB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin. Toxicol Appl Pharmacol 2008;226:30-37. (Pubitemid 350235577)
-
(2008)
Toxicology and Applied Pharmacology
, vol.226
, Issue.1
, pp. 30-37
-
-
Kalra, N.1
Bhui, K.2
Roy, P.3
Srivastava, S.4
George, J.5
Prasad, S.6
Shukla, Y.7
-
24
-
-
84859049029
-
Bromelain-induced apoptosis in GI-101A breast cancer cells
-
Dhandayuthapani S, Perez HD, Paroulek A, Chinnakkannu P, Kandalam U, Jaffe M, Rathinavelu A. Bromelain-induced apoptosis in GI-101A breast cancer cells. J Med Food 2012;15: 344-349.
-
(2012)
J Med Food
, vol.15
, pp. 344-349
-
-
Dhandayuthapani, S.1
Perez, H.D.2
Paroulek, A.3
Chinnakkannu, P.4
Kandalam, U.5
Jaffe, M.6
Rathinavelu, A.7
-
25
-
-
0028672814
-
Pineapple cysteine endopeptidases
-
Rowan AD, Buttle DJ. Pineapple cysteine endopeptidases.Methods Enzymol 1994;244:555-568.
-
(1994)
Methods Enzymol
, vol.244
, pp. 555-568
-
-
Rowan, A.D.1
Buttle, D.J.2
-
26
-
-
0029918951
-
Solution structure of bromelain inhibitor IV from pineapple stem: Structural similarity with Bowman-Birk trypsin/chymotrypsin inhibitor from soybean
-
Hatano K, Kojima M, Tanokura M, Takahashi K. Solution structure of bromelain inhibitor IV from pineapple stem: structural similarity with Bowman-Birk trypsin/chymotrypsin inhibitor from soybean. Biochemistry 1996;35:5379-5384.
-
(1996)
Biochemistry
, vol.35
, pp. 5379-5384
-
-
Hatano, K.1
Kojima, M.2
Tanokura, M.3
Takahashi, K.4
-
27
-
-
33645082924
-
Characterization of the acidic and basic limbs of a bell-shaped pH profile in the inhibitory activity of bromelain inhibitor VI
-
Hatano K, Sawano Y, Miyakawa T, Tanokura M. Characterization of the acidic and basic limbs of a bell-shaped pH profile in the inhibitory activity of bromelain inhibitor VI. Biopolymers 2006;81:309-319.
-
(2006)
Biopolymers
, vol.81
, pp. 309-319
-
-
Hatano, K.1
Sawano, Y.2
Miyakawa, T.3
Tanokura, M.4
-
28
-
-
13844289324
-
Proteinase activity and stability of natural bromelain preparations
-
DOI 10.1016/j.intimp.2004.12.007
-
Hale LP, Greer PK, Trinh CT, James CL. Proteinase activity and stability of natural bromelain preparations. Int Immunopharmacol 2005;5:783-793. (Pubitemid 40248332)
-
(2005)
International Immunopharmacology
, vol.5
, Issue.4
, pp. 783-793
-
-
Hale, L.P.1
Greer, P.K.2
Trinh, C.T.3
James, C.L.4
-
29
-
-
0030878648
-
Intestinal absorption of undegraded proteins in men: Presence of bromelain in plasma after oral intake
-
Castell JV, Friedrich G, Kuhn CS, Poppe GE. Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake. Am J Physiol 1997;273:G139-G146.
-
(1997)
Am J Physiol
, vol.273
-
-
Castell, J.V.1
Friedrich, G.2
Kuhn, C.S.3
Poppe, G.E.4
-
30
-
-
0028918590
-
Isolation and partial characterization of basic proteinases from stem bromelain
-
Harrach T, Eckert K, Schulze-Forster K, Nuck R, Grunow D, Maurer HR. Isolation and partial characterization of basic proteinases from stem bromelain. J Protein Chem 1995;14:41-52.
-
(1995)
J Protein Chem
, vol.14
, pp. 41-52
-
-
Harrach, T.1
Eckert, K.2
Schulze-Forster, K.3
Nuck, R.4
Grunow, D.5
Maurer, H.R.6
-
31
-
-
0031745660
-
Isolation and characterization of two forms of an acidic bromelain stem proteinase
-
DOI 10.1023/A:1022507316434
-
Harrach T, Eckert K, Maurer HR, Machleidt I, Machleidt W, Nuck R. Isolation and characterization of two forms of an acidic bromelain stem proteinase. J Protein Chem 1998;17:351-361. (Pubitemid 28242305)
-
(1998)
Journal of Protein Chemistry
, vol.17
, Issue.4
, pp. 351-361
-
-
Harrach, T.1
Eckert, K.2
Maurer, H.R.3
Machleidt, I.4
Machleidt, W.5
Nuck, R.6
-
32
-
-
0028109020
-
Purification and characterization of multiple forms of the pineapple-stem-derived cysteine proteinases ananain and comosain
-
Napper AD, Bennett SP, Borowski M, Holdridge MB, Leonard MJ, Rogers EE, Duan Y, Laursen RA, Reinhold B, Shames SL. Purification and characterization of multiple forms of the pineapple-stem-derived cysteine proteinases ananain and comosain. Biochem J 1994;301(Pt 3):727-735. (Pubitemid 24239305)
-
(1994)
Biochemical Journal
, vol.301
, Issue.3
, pp. 727-735
-
-
Napper, A.D.1
Bennet, S.P.2
Borowski, M.3
Holdridge, M.B.4
Leonard, M.J.C.5
Rogers, E.E.6
Duan, Y.7
Laursen, R.A.8
Reinhold, B.9
Shames, S.L.10
-
33
-
-
0025818591
-
Inactivation kinetics of enzyme pharmaceuticals in aqueous solution
-
Yoshioka S, Izutsu K, Aso Y, Takeda Y. Inactivation kinetics of enzyme pharmaceuticals in aqueous solution. Pharm Res 1991;8:480-484.
-
(1991)
Pharm Res
, vol.8
, pp. 480-484
-
-
Yoshioka, S.1
Izutsu, K.2
Aso, Y.3
Takeda, Y.4
-
34
-
-
77649180336
-
Bromelains activity and potential as an anti-cancer agent: Current evidence and perspectives
-
Chobotova K, Vernallis AB, Majid FA. Bromelains activity and potential as an anti-cancer agent: Current evidence and perspectives. Cancer Lett 2010;290:148-156.
-
(2010)
Cancer Lett
, vol.290
, pp. 148-156
-
-
Chobotova, K.1
Vernallis, A.B.2
Majid, F.A.3
-
35
-
-
0022353891
-
Inhibition of tumour growth in vitro by bromelain, an extract of the pineapple plant (Ananas comosus)
-
Taussig SJ, Szekerczes J, Batkin S. Inhibition of tumour growth in vitro by bromelain, an extract of the pineapple plant (Ananas comosus). Planta Med 1985;51(6):538-539. (Pubitemid 16176666)
-
(1985)
Planta Medica
, vol.NO. 6
, pp. 538-539
-
-
Taussig, S.J.1
Szekerczes, J.2
Batkin, S.3
-
36
-
-
0023720671
-
Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity
-
Batkin S, Taussig SJ, Szekerezes J. Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity. J Cancer Res Clin Oncol 1988;114:507-508.
-
(1988)
J Cancer Res Clin Oncol
, vol.114
, pp. 507-508
-
-
Batkin, S.1
Taussig, S.J.2
Szekerezes, J.3
-
37
-
-
0030440888
-
Selective modulation of cell adhesion molecules on lymphocytes by bromelain protease 5
-
Kleef R, Delohery TM, Bovbjerg DH. Selective modulation of cell adhesion molecules on lymphocytes by bromelain protease Pathobiology 1996;64:339-346. (Pubitemid 27174324)
-
(1996)
Pathobiology
, vol.64
, Issue.6
, pp. 339-346
-
-
Kleef, R.1
Delohery, T.M.2
Bovbjerg, D.H.3
-
38
-
-
0035946838
-
Bromelain activates murine macrophages and natural killer cells in vitro
-
DOI 10.1006/cimm.2001.1793
-
Engwerda CR, Andrew D,MurphyM,Mynott TL. Bromelain activates murine macrophages and natural killer cells in vitro. Cell Immunol 2001;210:5-10. (Pubitemid 32756936)
-
(2001)
Cellular Immunology
, vol.210
, Issue.1
, pp. 5-10
-
-
Engwerda, C.R.1
Andrew, D.2
Murphy, M.3
Mynott, T.L.4
-
39
-
-
20444421293
-
Fibroblast activation protein-α and dipeptidyl peptidase IV (CD26): Cell-surface proteases that activate cell signaling and are potential targets for cancer therapy
-
DOI 10.1016/j.drup.2005.03.002, PII S1368764605000257
-
Kelly T. Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy. Drug Resist Updat 2005;8:51-58. (Pubitemid 40797956)
-
(2005)
Drug Resistance Updates
, vol.8
, Issue.1-2
, pp. 51-58
-
-
Kelly, T.1
-
40
-
-
84876911612
-
Characterization of disease-associated Nlinked glycoproteins
-
Tian Y, Zhang H. Characterization of disease-associated Nlinked glycoproteins. Proteomics 2012.
-
(2012)
Proteomics
-
-
Tian, Y.1
Zhang, H.2
-
41
-
-
84863206749
-
Application of glycoproteomics for the discovery of biomarkers in lung cancer
-
Li QK, Gabrielson E, Zhang H. Application of glycoproteomics for the discovery of biomarkers in lung cancer. Proteomics Clin Appl 2012;6:244-256.
-
(2012)
Proteomics Clin Appl
, vol.6
, pp. 244-256
-
-
Li, Q.K.1
Gabrielson, E.2
Zhang, H.3
-
42
-
-
84873711075
-
The multidrug transporter P-glycoprotein in pharmacoresistance to antiepileptic drugs
-
Stepien KM, Tomaszewski M, Tomaszewska J, Czuczwar SJ.The multidrug transporter P-glycoprotein in pharmacoresistance to antiepileptic drugs. Pharmacol Rep 2012;64:1011-1019.
-
(2012)
Pharmacol Rep
, vol.64
, pp. 1011-1019
-
-
Stepien, K.M.1
Tomaszewski, M.2
Tomaszewska, J.3
Czuczwar, S.J.4
-
43
-
-
0035937526
-
Glycosylation and the immune system
-
DOI 10.1126/science.291.5512.2370
-
Rudd PM, Elliott T, Cresswell P, Wilson IA, Dwek RA. Glycosylation and the immune system. Science 2001;291: 2370-2376. (Pubitemid 32231792)
-
(2001)
Science
, vol.291
, Issue.5512
, pp. 2370-2376
-
-
Rudd, P.M.1
Elliott, T.2
Cresswell, P.3
Wilson, I.A.4
Dwek, R.A.5
-
44
-
-
0026655996
-
Structures and functions of the sugar chains of glycoproteins
-
Kobata A. Structures and functions of the sugar chains of glycoproteins. Eur J Biochem 1992;209:483-501.
-
(1992)
Eur J Biochem
, vol.209
, pp. 483-501
-
-
Kobata, A.1
-
45
-
-
0001094662
-
Glycobiology: Toward understanding the function of sugars
-
Dwek RA. Glycobiology: toward understanding the function of sugars. Chem Rev 1996;96:683-720. (Pubitemid 126649163)
-
(1996)
Chemical Reviews
, vol.96
, Issue.2
, pp. 683-720
-
-
Dwek, R.A.1
-
46
-
-
0030745147
-
Perspectives on the significance of altered glycosylation of glycoproteins in cancer
-
DOI 10.1023/A:1018580324971
-
Kim YJ, Varki A. Perspectives on the significance of altered glycosylation of glycoproteins in cancer. Glycoconj J 1997;14:569-576. (Pubitemid 27353200)
-
(1997)
Glycoconjugate Journal
, vol.14
, Issue.5
, pp. 569-576
-
-
Kim, Y.J.1
Varki, A.2
-
47
-
-
0036676975
-
Roles of Fc receptors in autoimmunity
-
Takai T. Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2002;2:580-592. (Pubitemid 37328733)
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.8
, pp. 580-592
-
-
Takai, T.1
-
48
-
-
84876927692
-
Identification of potential glycoprotein biomarkers in estrogen receptor positive (ER+) and negative (ER-) human breast cancer tissues by LCLTQ/FT-ICR mass spectrometry
-
Semaan SM, Wang X, Marshall AG, Sang QX. Identification of potential glycoprotein biomarkers in estrogen receptor positive (ER+) and negative (ER-) human breast cancer tissues by LCLTQ/FT-ICR mass spectrometry. J Cancer 2012;3:269-284.
-
(2012)
J Cancer
, vol.3
, pp. 269-284
-
-
Semaan, S.M.1
Wang, X.2
Marshall, A.G.3
Sang, Q.X.4
-
49
-
-
33745913025
-
Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer
-
DOI 10.1021/pr060010k
-
An HJ, Miyamoto S, Lancaster KS, Kirmiz C, Li B, Lam KS, Leiserowitz GS, Lebrilla CB. Profiling of glycans in serumfor the discovery of potential biomarkers for ovarian cancer. J Proteome Res 2006;5:1626-1635. (Pubitemid 44043097)
-
(2006)
Journal of Proteome Research
, vol.5
, Issue.7
, pp. 1626-1635
-
-
An, H.J.1
Miyamoto, S.2
Lancaster, K.S.3
Kirmiz, C.4
Li, B.5
Lam, K.S.6
Leiserowitz, G.S.7
Lebrilla, C.B.8
-
50
-
-
33846542649
-
A serum glycomics approach to breast cancer biomarkers
-
DOI 10.1074/mcp.M600171-MCP200
-
Kirmiz C, Li B, An HJ, Clowers BH, Chew HK, Lam KS, Ferrige A, Alecio R, Borowsky AD, Sulaimon S, Lebrilla CB, Miyamoto S. A serum glycomics approach to breast cancer biomarkers.Mol Cell Proteomics 2007;6:43-55. (Pubitemid 46152690)
-
(2007)
Molecular and Cellular Proteomics
, vol.6
, Issue.1
, pp. 43-55
-
-
Kirmiz, C.1
Li, B.2
An, H.J.3
Clowers, B.H.4
Chew, H.K.5
Lam, K.S.6
Ferrige, A.7
Alecio, R.8
Borowsky, A.D.9
Sulaimon, S.10
Lebrilla, C.B.11
Miyamoto, S.12
-
51
-
-
79960723943
-
A multiplexed bead assay for profiling glycosylation patterns on serum protein biomarkers of pancreatic cancer
-
Li C, Zolotarevsky E, Thompson I, Anderson MA, Simeone DM, Casper JM, Mullenix MC, Lubman DM. A multiplexed bead assay for profiling glycosylation patterns on serum protein biomarkers of pancreatic cancer. Electrophoresis 2011;32:2028-2035.
-
(2011)
Electrophoresis
, vol.32
, pp. 2028-2035
-
-
Li, C.1
Zolotarevsky, E.2
Thompson, I.3
Anderson, M.A.4
Simeone, D.M.5
Casper, J.M.6
Mullenix, M.C.7
Lubman, D.M.8
-
52
-
-
20044377211
-
Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans
-
DOI 10.1073/pnas.0408928102
-
Block TM, Comunale MA, Lowman M, Steel LF, Romano PR, Fimmel C, Tennant BC, London WT, Evans AA, Blumberg BS, Dwek RA, Mattu TS, Mehta AS. Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans. Proc Natl Acad Sci USA 2005;102:779-784. (Pubitemid 40282742)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.3
, pp. 779-784
-
-
Block, T.M.1
Comunale, M.A.2
Lowman, M.3
Steel, L.F.4
Romano, P.R.5
Fimmel, C.6
Tennant, B.C.7
London, W.T.8
Evans, A.A.9
Blumberg, B.S.10
Dwek, R.A.11
Mattu, T.S.12
Mehta, A.S.13
-
53
-
-
42549092735
-
Targeting the human MUC1 oncoprotein: A tale of two proteins
-
KufeDW. Targeting the human MUC1 oncoprotein: a tale of two proteins. Cancer BiolTher 2008;7:81-84.
-
(2008)
Cancer BiolTher
, vol.7
, pp. 81-84
-
-
Kufe, D.W.1
-
54
-
-
18544362183
-
Molecular-pathological prognostic factors of gastric cancer: A review
-
DOI 10.1007/s10120-005-0320-0
-
Yasui W, Oue N, Aung PP, Matsumura S, Shutoh M, Nakayama H.Molecular-pathological prognostic factors of gastric cancer: a review. Gastric Cancer 2005;8:86-94. (Pubitemid 40655517)
-
(2005)
Gastric Cancer
, vol.8
, Issue.2
, pp. 86-94
-
-
Yasui, W.1
Oue, N.2
Phyu, P.A.3
Matsumura, S.4
Shutoh, M.5
Nakayama, H.6
-
55
-
-
18644377457
-
The role of EGF-R expression on patient survival in lung cancer: A systematic review with meta-analysis
-
DOI 10.1183/09031936.02.00296502
-
Meert AP, Martin B, Delmotte P, Moriya T, Niikura H, Terada Y, Sato S,Okamura K, Yaegashi N.The role of EGF-R expression on patient survival in lung cancer: a systematic reviewwithmetaanalysis. Eur Respir J 2002;20:975-981. (Pubitemid 35175137)
-
(2002)
European Respiratory Journal
, vol.20
, Issue.4
, pp. 975-981
-
-
Meert, A.-P.1
Martin, B.2
Delmotte, P.3
Berghmans, T.4
Lafitte, J.-J.5
Mascaux, C.6
Paesmans, M.7
Steels, E.8
Verdebout, J.-M.9
Sculier, J.-P.10
-
56
-
-
2942511574
-
Role of osteopontin in tumour progression
-
DOI 10.1038/sj.bjc.6601839
-
Rittling SR, Chambers AF. Role of osteopontin in tumour progression. Br J Cancer 2004;90:1877-1881. (Pubitemid 38746324)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.10
, pp. 1877-1881
-
-
Rittling, S.R.1
Chambers, A.F.2
-
57
-
-
17644405761
-
Ber-EP4 and anti-calretinin antibodies: A useful combination for differential diagnosis of various histological types of ovarian cancer cells and mesothelial cells
-
DOI 10.1620/tjem.206.31
-
Okamoto S, Ito K, Sasano H, Moriya T, Niikura H, Terada Y, Sato S, OkamuraK, YaegashiN. Ber-EP4 and anti-calretinin antibodies: a useful combination for differential diagnosis of various histological types of ovarian cancer cells and mesothelial cells. Tohoku J Exp Med 2005;206:31-40. (Pubitemid 40568161)
-
(2005)
Tohoku Journal of Experimental Medicine
, vol.206
, Issue.1
, pp. 31-40
-
-
Okamoto, S.1
Ito, K.2
Sasano, H.3
Moriya, T.4
Niikura, H.5
Terada, Y.6
Sato, S.7
Okamura, K.8
Yaegashi, N.9
-
58
-
-
0141921933
-
The role of HER-2/neu expression on the survival of patients with lung cancer: A systematic review of the literature
-
DOI 10.1038/sj.bjc.6601252
-
Meert AP, Martin B, Paesmans M, Berghmans T, Mascaux C, Verdebout JM,Delmotte P, Lafitte JJ, Sculier JP.Therole of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature. Br J Cancer 2003;89:959-965. (Pubitemid 37239194)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.6
, pp. 959-965
-
-
Meert, A.-P.1
Martin, B.2
Paesmans, M.3
Berghmans, T.4
Mascaux, C.5
Verdebout, J.-M.6
Delmotte, P.7
Lafitte, J.-J.8
Sculier, J.-P.9
-
59
-
-
84863711486
-
Context dependent role of the CD36-thrombospondin-histidine-rich glycoprotein axis in tumor angiogenesis and growth
-
Hale JS, Li M, Sinyuk M, Jahnen-Dechent W, Lathia JD, Silverstein RL. Context dependent role of the CD36-thrombospondin-histidine-rich glycoprotein axis in tumor angiogenesis and growth. PLoS One 2012;7:e40033.
-
(2012)
PLoS One
, vol.7
-
-
Hale, J.S.1
Li, M.2
Sinyuk, M.3
Jahnen-Dechent, W.4
Lathia, J.D.5
Silverstein, R.L.6
-
60
-
-
0038182549
-
Glycoprotein hormone receptors: Determinants in leucine-rich repeats responsible for ligand specificity
-
DOI 10.1093/emboj/cdg260
-
Smits G, Campillo M, Govaerts C, Janssens V, Richter C, Vassart G, Pardo L, Costagliola S. Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity. EMBO J 2003;22:2692-2703. (Pubitemid 36712366)
-
(2003)
EMBO Journal
, vol.22
, Issue.11
, pp. 2692-2703
-
-
Smits, G.1
Campillo, M.2
Govaerts, C.3
Janssens, V.4
Richter, C.5
Vassart, G.6
Pardo, L.7
Costagliola, S.8
-
61
-
-
0023735002
-
The glycoprotein hormones: Recent studies of structure-function relationships
-
Ryan RJ, Charlesworth MC, McCormick DJ, Milius RP, Keutmann HT. The glycoprotein hormones: recent studies of structure-function relationships. FASEB J 1988;2:2661-2669.
-
(1988)
FASEB J
, vol.2
, pp. 2661-2669
-
-
Ryan, R.J.1
Charlesworth, M.C.2
McCormick, D.J.3
Milius, R.P.4
Keutmann, H.T.5
-
62
-
-
48949089988
-
Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides
-
Stadlmann J, Pabst M, Kolarich D, Kunert R, Altmann F. Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides. Proteomics 2008;8:2858-2871.
-
(2008)
Proteomics
, vol.8
, pp. 2858-2871
-
-
Stadlmann, J.1
Pabst, M.2
Kolarich, D.3
Kunert, R.4
Altmann, F.5
-
65
-
-
34547678389
-
MUC1 cell surface mucin is a critical element of the mucosal barrier to infection
-
DOI 10.1172/JCI26705
-
McAuley JL, Linden SK, Png CW, King RM, Pennington HL, Gendler SJ, Florin TH, Hill GR, Korolik V, McGuckin MA. MUC1 cell surfacemucin is a critical element of themucosal barrier to infection. J Clin Invest 2007;117:2313-2324. (Pubitemid 47219576)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2313-2324
-
-
McAuley, J.L.1
Linden, S.K.2
Chin, W.P.3
King, R.M.4
Pennington, H.L.5
Gendler, S.J.6
Florin, T.H.7
Hill, G.R.8
Korolik, V.9
McGuckin, M.A.10
-
66
-
-
0030984471
-
Mucin antigen expression in gastric carcinomas of young and old adults
-
DOI 10.1016/S0046-8177(97)90059-9
-
Sakamoto H, Yonezawa S,Utsunomiya T, Tanaka S, Kim YS, Sato E. Mucin antigen expression in gastric carcinomas of young and old adults. Hum Pathol 1997;28:1056-1065. (Pubitemid 27388107)
-
(1997)
Human Pathology
, vol.28
, Issue.9
, pp. 1056-1065
-
-
Sakamoto, H.1
Yonezawa, S.2
Utsunomiya, T.3
Tanaka, S.4
Kim, Y.S.5
Sato, E.6
-
67
-
-
75149124701
-
MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1
-
Sachdeva M, Mo YY. MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res 2010;70:378-387.
-
(2010)
Cancer Res
, vol.70
, pp. 378-387
-
-
Sachdeva, M.1
Mo, Y.Y.2
-
68
-
-
2442693937
-
L pathways in rat 3Y1 fibroblasts
-
DOI 10.1074/jbc.M310538200
-
Raina D, Kharbanda S, Kufe D. The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J Biol Chem 2004;279:20607-20612. (Pubitemid 38656454)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 20607-20612
-
-
Raina, D.1
Kharbanda, S.2
Kufe, D.3
-
69
-
-
7944230166
-
MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress
-
DOI 10.1074/jbc.M408027200
-
Yin L, Huang L, Kufe D. MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem 2004;279:45721-45727. (Pubitemid 39491562)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.44
, pp. 45721-45727
-
-
Yin, L.1
Huang, L.2
Kufe, D.3
-
70
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
-
DOI 10.1016/S1535-6108(04)00020-0, PII S1535610804000200
-
Ren J, Agata N, Chen D, Li Y, Yu WH, Huang L, Raina D, Chen W, Kharbanda S, Kufe D. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell 2004;5:163-175. (Pubitemid 38283802)
-
(2004)
Cancer Cell
, vol.5
, Issue.2
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
Li, Y.4
Yu, W.-H.5
Huang, L.6
Raina, D.7
Chen, W.8
Kharbanda, S.9
Kufe, D.10
-
71
-
-
25144504517
-
Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer
-
DOI 10.1038/modpathol.3800445, PII 3800445
-
Rakha EA, Boyce RW, Abd El-Rehim D, Kurien T, Green AR, Paish EC, Robertson JF, Ellis IO. Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer.Mod Pathol 2005;18:1295-1304. (Pubitemid 41348648)
-
(2005)
Modern Pathology
, vol.18
, Issue.10
, pp. 1295-1304
-
-
Rakha, E.A.1
Boyce, R.W.G.2
El-Rehim, D.A.3
Kurien, T.4
Green, A.R.5
Paish, E.C.6
Robertson, J.F.R.7
Ellis, I.O.8
-
72
-
-
34548565758
-
MUC-1 gene is associated with prostate cancer death: A 20-year follow-up of a population-based study in Sweden
-
DOI 10.1038/sj.bjc.6603944, PII 6603944
-
Andren O, Fall K, Andersson SO, Rubin MA, Bismar TA, Karlsson M, Johansson JE, Mucci LA. MUC-1 gene is associated with prostate cancer death: a 20-year follow-up of a populationbased study in Sweden. Br J Cancer 2007;97:730-734. (Pubitemid 47396290)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.6
, pp. 730-734
-
-
Andren, O.1
Fall, K.2
Andersson, S.-O.3
Rubin, M.A.4
Bismar, T.A.5
Karlsson, M.6
Johansson, J.-E.7
Mucci, L.A.8
-
73
-
-
77951791725
-
MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients
-
MacDermed DM, Khodarev NN, Pitroda SP, Edwards DC, Pelizzari CA, Huang L, Kufe DW, Weichselbaum RR. MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients. BMC Med Genomics 2010;3:16.
-
(2010)
BMC Med Genomics
, vol.3
, pp. 16
-
-
MacDermed, D.M.1
Khodarev, N.N.2
Pitroda, S.P.3
Edwards, D.C.4
Pelizzari, C.A.5
Huang, L.6
Kufe, D.W.7
Weichselbaum, R.R.8
-
74
-
-
79959716214
-
Soluble MUC1 and serum MUC1-specific antibodies are potential prognostic biomarkers for platinum-resistant ovarian cancer
-
Budiu RA, Mantia-Smaldone G, Elishaev E, Chu T, Thaller J, McCabe K, Lenzner D, Edwards RP, Vlad AM. Soluble MUC1 and serum MUC1-specific antibodies are potential prognostic biomarkers for platinum-resistant ovarian cancer. Cancer Immunol Immunother 2011;60:975-984.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 975-984
-
-
Budiu, R.A.1
Mantia-Smaldone, G.2
Elishaev, E.3
Chu, T.4
Thaller, J.5
McCabe, K.6
Lenzner, D.7
Edwards, R.P.8
Vlad, A.M.9
-
75
-
-
51549099068
-
MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma
-
Tinder TL, Subramani DB, Basu GD, Bradley JM, Schettini J, Million A, Skaar T, Mukherjee P. MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma. J Immunol 2008;181:3116-3125.
-
(2008)
J Immunol
, vol.181
, pp. 3116-3125
-
-
Tinder, T.L.1
Subramani, D.B.2
Basu, G.D.3
Bradley, J.M.4
Schettini, J.5
Million, A.6
Skaar, T.7
Mukherjee, P.8
-
76
-
-
84859494423
-
Downregulation of MUC1 expression and its recognition by CD8(+) T cells on the surface of malignant pleural mesothelioma cells treated with HDACi
-
Roulois D, Blanquart C, Panterne C, Gueugnon F, Gregoire M, Fonteneau JF. Downregulation of MUC1 expression and its recognition by CD8(+) T cells on the surface of malignant pleural mesothelioma cells treated with HDACi. Eur J Immunol 2012;42:783-789.
-
(2012)
Eur J Immunol
, vol.42
, pp. 783-789
-
-
Roulois, D.1
Blanquart, C.2
Panterne, C.3
Gueugnon, F.4
Gregoire, M.5
Fonteneau, J.F.6
-
77
-
-
43249083136
-
Overexpression and altered glycosylation of MUC1 in malignant mesothelioma
-
DOI 10.1038/sj.bjc.6604340, PII 6604340
-
Creaney J, Segal A, Sterrett G, Platten MA, Baker E, Murch AR, Nowak AK, Robinson BW,MillwardMJ. Overexpression and altered glycosylation of MUC1 in malignant mesothelioma. Br J Cancer 2008;98:1562-1569. (Pubitemid 351652333)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.9
, pp. 1562-1569
-
-
Creaney, J.1
Segal, A.2
Sterrett, G.3
Platten, M.A.4
Baker, E.5
Murch, A.R.6
Nowak, A.K.7
Robinson, B.W.S.8
Millward, M.J.9
-
78
-
-
0024361527
-
Structural analysis of the DF3 human breast carcinoma-associated protein
-
Abe M, Kufe D. Structural analysis of the DF3 human breast carcinoma-associated protein. Cancer Res 1989;49:2834-2839. (Pubitemid 19148611)
-
(1989)
Cancer Research
, vol.49
, Issue.11
, pp. 2834-2839
-
-
Abe, M.1
Kufe, D.2
-
79
-
-
0035918199
-
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
-
Schroeder JA, Thompson MC, Gardner MM, Gendler SJ. Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J Biol Chem 2001;276:13057-13064.
-
(2001)
J Biol Chem
, vol.276
, pp. 13057-13064
-
-
Schroeder, J.A.1
Thompson, M.C.2
Gardner, M.M.3
Gendler, S.J.4
-
80
-
-
34347230948
-
Platelet-derived growth factor receptor β-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells
-
DOI 10.1158/0008-5472.CAN-06-4647
-
Singh PK, Wen Y, Swanson BJ, Shanmugam K, Kazlauskas A, Cerny RL, Gendler SJ, Hollingsworth MA. Platelet-derived growth factor receptor beta-mediated phosphorylation ofMUC1 enhances invasiveness in pancreatic adenocarcinoma cells. Cancer Res 2007;67:5201-5210. (Pubitemid 46997258)
-
(2007)
Cancer Research
, vol.67
, Issue.11
, pp. 5201-5210
-
-
Singh, P.K.1
Wen, Y.2
Swanson, B.J.3
Shanmugam, K.4
Kazlauskas, A.5
Cerny, R.L.6
Gendler, S.J.7
Hollingsworth, M.A.8
-
81
-
-
33845296622
-
MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling
-
DOI 10.1158/1541-7786.MCR-06-0204
-
Ren J, Raina D, Chen W, Li G,Huang L, KufeD.MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling. Mol Cancer Res 2006;4:873-883. (Pubitemid 44877017)
-
(2006)
Molecular Cancer Research
, vol.4
, Issue.11
, pp. 873-883
-
-
Ren, J.1
Raina, D.2
Chen, W.3
Li, G.4
Huang, L.5
Kufe, D.6
-
82
-
-
0041828907
-
Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein
-
Li Y, Yu WH, Ren J, Chen W, Huang L, Kharbanda S, Loda M, Kufe D. Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein. Mol Cancer Res 2003;1:765-775. (Pubitemid 37025595)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.10
, pp. 765-775
-
-
Li, Y.1
Yu, W.-H.2
Ren, J.3
Chen, W.4
Huang, L.5
Kharbanda, S.6
Loda, M.7
Kufe, D.8
-
83
-
-
0141459073
-
Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail
-
DOI 10.1016/j.bbrc.2003.09.030
-
Wang H, Lillehoj EP, Kim KC. Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail. Biochem Biophys Res Commun 2003;310:341-346. (Pubitemid 37163669)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.310
, Issue.2
, pp. 341-346
-
-
Wang, H.1
Lillehoj, E.P.2
Kim, K.C.3
-
84
-
-
0035794215
-
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinomaassociated antigen withGSK3 beta and beta-catenin
-
Li Y, Kuwahara H, Ren J, Wen G, Kufe D. The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinomaassociated antigen withGSK3 beta and beta-catenin. J Biol Chem 2001;276:6061-6064.
-
(2001)
J Biol Chem
, vol.276
, pp. 6061-6064
-
-
Li, Y.1
Kuwahara, H.2
Ren, J.3
Wen, G.4
Kufe, D.5
-
85
-
-
0037124099
-
Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling
-
DOI 10.1074/jbc.M200436200
-
Ren J, Li Y, Kufe D. Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling. J Biol Chem 2002;277:17616-17622. (Pubitemid 34967564)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.20
, pp. 17616-17622
-
-
Ren, J.1
Li, Y.2
Kufe, D.3
-
86
-
-
0141733054
-
Nuclear association of the cytoplasmic tail of MUC1 and β-catenin
-
DOI 10.1074/jbc.M304333200
-
Wen Y, Caffrey TC,WheelockMJ, Johnson KR, Hollingsworth MA. Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin. J Biol Chem 2003;278:38029-38039. (Pubitemid 37175334)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 38029-38039
-
-
Wen, Y.1
Caffrey, T.C.2
Wheelock, M.J.3
Johnson, K.R.4
Hollingsworth, M.A.5
-
87
-
-
1542722230
-
MUC1 can interact with adenomatous polyposis coli in breast cancer
-
DOI 10.1016/j.bbrc.2004.02.072, PII S0006291X04003201
-
Hattrup CL, Fernandez-Rodriguez J, Schroeder JA, Hansson GC, Gendler SJ. MUC1 can interact with adenomatous polyposis coli in breast cancer. Biochem Biophys Res Commun 2004;316:364-369. (Pubitemid 38338601)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.316
, Issue.2
, pp. 364-369
-
-
Hattrup, C.L.1
Fernandez-Rodriguez, J.2
Schroeder, J.A.3
Hansson, G.C.4
Gendler, S.J.5
-
88
-
-
13844262819
-
Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
-
DOI 10.1016/j.ccr.2005.01.008
-
Wei X, Xu H, Kufe D. Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 2005;7:167-178. (Pubitemid 40248342)
-
(2005)
Cancer Cell
, vol.7
, Issue.2
, pp. 167-178
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
89
-
-
0034812739
-
ctn
-
DOI 10.1006/bbrc.2001.4383
-
Li Y, Kufe D. The Human DF3/MUC1 carcinoma-associated antigen signals nuclear localization of the catenin p120(ctn). Biochem Biophys Res Commun 2001;281:440-443. (Pubitemid 32928175)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.281
, Issue.2
, pp. 440-443
-
-
Li, Y.1
Kufe, D.2
-
90
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501. (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
91
-
-
0032560796
-
Akt activation by growth factors is a multiple-step process: The role of the PH domain
-
Bellacosa A, Chan TO, Ahmed NN, Datta K,MalstromS, Stokoe D,McCormick F, Feng J, Tsichlis P. Akt activationby growthfactors is a multiple-step process: the role of the PH domain. Oncogene 1998;17:313-325. (Pubitemid 28383008)
-
(1998)
Oncogene
, vol.17
, Issue.3
, pp. 313-325
-
-
Bellacosa, A.1
Chan, T.O.2
Ahmed, N.N.3
Datta, K.4
Malstrom, S.5
Stokoe, D.6
McCormick, F.7
Feng, J.8
Tsichlis, P.9
-
92
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
DOI 10.1126/science.277.5325.567
-
Stokoe D, Stephens LR, Copeland T, Gaffney PR, Reese CB, Painter GF, Holmes AB, McCormick F, Hawkins PT. Dual role of phosphatidylinositol-3,4,5- trisphosphate in the activation of protein kinase B. Science 1997;277:567-570. (Pubitemid 27369005)
-
(1997)
Science
, vol.277
, Issue.5325
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.J.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
93
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery
-
DOI 10.1016/S0092-8674(00)80405-5
-
Datta SR,DudekH, TaoX,Masters S, FuH, GotohY,Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241. (Pubitemid 27456390)
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Xu, T.3
Masters, S.4
Haian, F.5
Gotoh, Y.6
Greenberg, M.E.7
-
94
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, Reed JC. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998;282:1318-1321. (Pubitemid 28524494)
-
(1998)
Science
, vol.282
, Issue.5392
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
96
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
DOI 10.1038/ncb1101-973
-
Zhou BP, Liao Y, Xia W, Zou Y, Spohn B,HungMC.HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol 2001;3:973-982. (Pubitemid 34428742)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.11
, pp. 973-982
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Zou, Y.4
Spohn, B.5
Hung, M.-C.6
-
97
-
-
0021874349
-
Monoclonal antibody DF3 correlates with tumor differentiation and hormone receptor status in breast cancer patients
-
DOI 10.1007/BF01806021
-
Lundy J, Thor A, Maenza R, Schlom J, Forouhar F, Testa M, Kufe D. Monoclonal antibody DF3 correlates with tumor differentiation and hormone receptor status in breast cancer patients. Breast Cancer Res Treat 1985;5:269-276. (Pubitemid 15060454)
-
(1985)
Breast Cancer Research and Treatment
, vol.5
, Issue.3
, pp. 269-276
-
-
Lundy, J.1
Thor, A.2
Maenza, R.3
-
98
-
-
33751328591
-
MUC1 gene overexpressed in breast cancer: Structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERalpha) in regulation of the MUC1 gene expression
-
Zaretsky JZ, Barnea I, Aylon Y, Gorivodsky M, Wreschner DH, Keydar I. MUC1 gene overexpressed in breast cancer: structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERalpha) in regulation of the MUC1 gene expression. Mol Cancer 2006;5:57.
-
(2006)
Mol Cancer
, vol.5
, pp. 57
-
-
Zaretsky, J.Z.1
Barnea, I.2
Aylon, Y.3
Gorivodsky, M.4
Wreschner, D.H.5
Keydar, I.6
-
99
-
-
30744474431
-
MUC1 oncoprotein stabilizes and activates estrogen receptor α
-
DOI 10.1016/j.molcel.2005.11.030, PII S1097276505019015
-
Wei X, XuH, Kufe D. MUC1 oncoprotein stabilizes and activates estrogen receptor alpha. Mol Cell 2006;21:295-305. (Pubitemid 43099944)
-
(2006)
Molecular Cell
, vol.21
, Issue.2
, pp. 295-305
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
100
-
-
0042818006
-
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
-
DOI 10.1074/jbc.M301987200
-
Yin L, Li Y, Ren J, Kuwahara H, Kufe D. Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J Biol Chem 2003;278:35458-35464. (Pubitemid 37102316)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.37
, pp. 35458-35464
-
-
Yin, L.1
Li, Y.2
Ren, J.3
Kuwahara, H.4
Kufe, D.5
-
101
-
-
34948826922
-
Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: Overcoming cellular barriers for therapeutic gain
-
DOI 10.1038/sj.bjc.6603972, PII 6603972
-
Kalra AV, Campbell RB.Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer 2007;97:910-918. (Pubitemid 47519315)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.7
, pp. 910-918
-
-
Kalra, A.V.1
Campbell, R.B.2
-
102
-
-
34249878202
-
Mucin expression profile in pancreatic cancer and the precursor lesions
-
DOI 10.1007/s00534-006-1169-2
-
Nagata K, Horinouchi M, Saitou M, Higashi M, Nomoto M, Goto M, Yonezawa S. Mucin expression profile in pancreatic cancer and the precursor lesions. J Hepatobiliary Pancreat Surg 2007;14:243-254. (Pubitemid 46863913)
-
(2007)
Journal of Hepato-Biliary-Pancreatic Surgery
, vol.14
, Issue.3
, pp. 243-254
-
-
Nagata, K.1
Horinouchi, M.2
Saitou, M.3
Higashi, M.4
Nomoto, M.5
Goto, M.6
Yonezawa, S.7
-
103
-
-
23444448425
-
MUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas
-
DOI 10.1136/jcp.2004.023572
-
Saitou M, Goto M, Horinouchi M, Tamada S, Nagata K, Hamada T, Osako M, Takao S, Batra SK, Aikou T, Imai K, Yonezawa S. MUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas. J Clin Pathol 2005;58:845-852. (Pubitemid 41113392)
-
(2005)
Journal of Clinical Pathology
, vol.58
, Issue.8
, pp. 845-852
-
-
Saitou, M.1
Goto, M.2
Horinouchi, M.3
Tamada, S.4
Nagata, K.5
Hamada, T.6
Osako, M.7
Takao, S.8
Batra, S.K.9
Aikou, T.10
Imai, K.11
Yonezawa, S.12
-
104
-
-
0000533014
-
A plant protease for potentiation of and possible replacement of antibiotics
-
Neubauer RA. A plant protease for potentiation of and possible replacement of antibiotics. Exp Med Surg 1961;19:143-160.
-
(1961)
Exp Med Surg
, vol.19
, pp. 143-160
-
-
Neubauer, R.A.1
-
105
-
-
0028058867
-
Bromelain proteinase F9 augments human lymphocyte-mediated growth inhibition of various tumor cells in vitro
-
Garbin F,Harrach T, Eckert K,MaurerH. Bromelain proteinasef9 augments human lymphocyte-mediated growth-inhibition of various tumor-cells in-vitro. Int J Oncol 1994;5:197-203. (Pubitemid 24231845)
-
(1994)
International Journal of Oncology
, vol.5
, Issue.2
, pp. 197-203
-
-
Garbin, F.1
Harrach, T.2
Eckert, K.3
Maurer, H.R.4
-
106
-
-
0035215944
-
Bromelain reversibly inhibits invasive properties of glioma cells
-
DOI 10.1038/sj.neo.7900196
-
Tysnes BB,MaurerHR, Porwol T, Probst B, Bjerkvig R,Hoover F. Bromelain reversibly inhibits invasive properties of glioma cells. Neoplasia 2001;3:469-479. (Pubitemid 33151013)
-
(2001)
Neoplasia
, vol.3
, Issue.6
, pp. 469-479
-
-
Tysnes, B.B.1
Maurer, H.R.2
Porwol, T.3
Probst, B.4
Bjerkvig, R.5
Hoover, F.6
-
107
-
-
34948835723
-
Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa
-
DOI 10.1593/neo.07427
-
Guimaraes-Ferreira CA, Rodrigues EG, Mortara RA, Cabral H, Serrano FA, Ribeiro-dos-Santos R, Travassos LR. Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa. Neoplasia 2007;9:723-733. (Pubitemid 47523234)
-
(2007)
Neoplasia
, vol.9
, Issue.9
, pp. 723-733
-
-
Guimaraes-Ferreira, C.A.1
Rodrigues, E.G.2
Mortara, R.A.3
Cabral, H.4
Serrano, F.A.5
Ribeiro-Dos-Santos, R.6
Travassos, L.R.7
-
108
-
-
0033197918
-
Bromelain, from pineapple stems, proteolytically blocks activation of extracellular regulated kinase-2 in T cells
-
Mynott TL, Ladhams A, Scarmato P, Engwerda CR. Bromelain, from pineapple stems, proteolytically blocks activation of extracellular regulated kinase-2 in T cells. J Immunol 1999;163:2568-2575. (Pubitemid 29399179)
-
(1999)
Journal of Immunology
, vol.163
, Issue.5
, pp. 2568-2575
-
-
Mynott, T.L.1
Ladhams, A.2
Scarmato, P.3
Engwerda, C.R.4
-
109
-
-
57649171078
-
Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours
-
Kalra AV, Campbell RB. Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours. Eur J Cancer 2009;45:164-173.
-
(2009)
Eur J Cancer
, vol.45
, pp. 164-173
-
-
Kalra, A.V.1
Campbell, R.B.2
-
110
-
-
0015452986
-
Anticancer treatment and bromelains
-
Gerard G. Anticancer treatment and bromelains. Agressologie 1972;13:261-274.
-
(1972)
Agressologie
, vol.13
, pp. 261-274
-
-
Gerard, G.1
-
112
-
-
0018424516
-
DIE RESORPTION EINES PROTEOLYTISCHEN ENZYMS PFLANZLICHEN URSPRUNGES AUS DEM MAGEN-DARM-TRAKT IN DAS BLUT UND IN DIE LYMPHE VON ERWACHSENEN RATTEN
-
Seifert J, Ganser R, Brendel W. Absorption of a proteolytic enzyme originating from plants out of the gastro-intestinal tract into blood and lymph of rats (authors transl). Z Gastroenterol 1979;17:1-8. (Pubitemid 9084659)
-
(1979)
Zeitschrift fur Gastroenterologie
, vol.17
, Issue.1
, pp. 1-8
-
-
Seifert, J.1
Ganser, R.2
Brendel, W.3
-
113
-
-
0031915998
-
Prognostic and predictive factors in breast cancer by immunohistochemical analysis
-
Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol 1998;11:155-168. (Pubitemid 28144151)
-
(1998)
Modern Pathology
, vol.11
, Issue.2
, pp. 155-168
-
-
Allred, D.C.1
Harvey, J.M.2
Berardo, M.3
Clark, G.M.4
-
114
-
-
35648983903
-
Inflammation and cancer: An ancient link with novel potentials
-
DOI 10.1002/ijc.23173
-
Hussain SP,Harris CC. Inflammation and cancer: an ancient link with novel potentials. Int J Cancer 2007;121:2373-2380. (Pubitemid 350022405)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.11
, pp. 2373-2380
-
-
Hussain, S.P.1
Harris, C.C.2
-
115
-
-
36148978529
-
Cyclooxygenases, prostanoids, and tumor progression
-
DOI 10.1007/s10555-007-9096-5, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
-
Wang MT, Honn KV, Nie D. Cyclooxygenases, prostanoids, and tumor progression. Cancer Metastasis Rev 2007;26:525-534. (Pubitemid 350115125)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.3-4
, pp. 525-534
-
-
Wang, M.-T.1
Honn, K.V.2
Nie, D.3
-
116
-
-
33645794044
-
Cross-linked bromelain inhibits lipopolysaccharide-induced cytokine production involving cellular signaling suppression in rats
-
Hou RC, Chen YS, Huang JR, Jeng KC. Cross-linked bromelain inhibits lipopolysaccharide-induced cytokine production involving cellular signaling suppression in rats. J Agric Food Chem 2006;54:2193-2198.
-
(2006)
J Agric Food Chem
, vol.54
, pp. 2193-2198
-
-
Hou, R.C.1
Chen, Y.S.2
Huang, J.R.3
Jeng, K.C.4
-
117
-
-
17644394616
-
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
-
DOI 10.1016/j.ccr.2005.02.013
-
Balkwill F, Charles KA,Mantovani A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005;7:211-217. (Pubitemid 40568680)
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 211-217
-
-
Balkwill, F.1
Charles, K.A.2
Mantovani, A.3
-
118
-
-
33744548730
-
Signal transduction of inflammatory cytokines and tumor development
-
DOI 10.1111/j.1349-7006.2006.00197.x
-
Yoshimura A. Signal transduction of inflammatory cytokines and tumor development. Cancer Sci 2006;97:439-447. (Pubitemid 43811583)
-
(2006)
Cancer Science
, vol.97
, Issue.6
, pp. 439-447
-
-
Yoshimura, A.1
-
119
-
-
0033662405
-
CD4+ T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells
-
Qin Z, Blankenstein T. CD4+ T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells. Immunity 2000;12:677-686.
-
(2000)
Immunity
, vol.12
, pp. 677-686
-
-
Qin, Z.1
Blankenstein, T.2
-
120
-
-
0027496317
-
Cytokine synthesis in human peripheral blood mononuclear cells after oral administration of polyenzyme preparations
-
Desser L, Rehberger A, Kokron E, Paukovits W. Cytokine synthesis in human peripheral blood mononuclear cells after oral administration of polyenzyme preparations. Oncology 1993;50:403-407. (Pubitemid 23323706)
-
(1993)
Oncology
, vol.50
, Issue.6
, pp. 403-407
-
-
Desser, L.1
Rehberger, A.2
Kokron, E.3
Paukovits, W.4
-
121
-
-
0028171487
-
Proteolytic enzymes and amylase induce cytokine production in human peripheral blood mononuclear cells in vitro
-
Desser L, Rehberger A, Paukovits W. Proteolytic enzymes and amylase induce cytokine production in human peripheral blood mononuclear cells in vitro. Cancer Biother 1994;9:253-263.
-
(1994)
Cancer Biother
, vol.9
, pp. 253-263
-
-
Desser, L.1
Rehberger, A.2
Paukovits, W.3
-
122
-
-
24144442688
-
In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans
-
Barth H, Guseo A, Klein R. In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans. Eur J Med Res 2005;10:325-331. (Pubitemid 41226978)
-
(2005)
European Journal of Medical Research
, vol.10
, Issue.8
, pp. 325-331
-
-
Barth, H.1
Guseo, A.2
Klein, R.3
-
123
-
-
39549098128
-
RAGE signaling sustains inflammation and promotes tumor development
-
DOI 10.1084/jem.20070679
-
Gebhardt C, Riehl A, Durchdewald M, Nemeth J, Furstenberger G, Muller-Decker K, Enk A, Arnold B, Bierhaus A, Nawroth PP, Hess J, Angel P. RAGE signaling sustains inflammation and promotes tumor development. J Exp Med 2008;205: 275-285. (Pubitemid 351281593)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.2
, pp. 275-285
-
-
Gebhardt, C.1
Riehl, A.2
Durchdewald, M.3
Nemeth, J.4
Furstenberger, G.5
Muller-Decker, K.6
Enk, A.7
Arnold, B.8
Bierhaus, A.9
Nawroth, P.P.10
Hess, J.11
Angel, P.12
-
124
-
-
0035526694
-
Chemistry and pathobiology of advanced glycation end products
-
Schleicher ED, Bierhaus A, Haring HU, Nawroth PP, Lehmann R. Chemistry and pathobiology of advanced glycation end products. Contrib Nephrol 2001;1-9. (Pubitemid 33816224)
-
(2001)
Contributions to Nephrology
, vol.131
, pp. 1-9
-
-
Schleicher, E.D.1
Bierhaus, A.2
Haring, H.-U.3
Nawroth, P.P.4
Lehmann, R.5
-
125
-
-
0037455982
-
Genotoxicity of advanced glycation end products in mammalian cells
-
DOI 10.1016/S0304-3835(02)00626-2
-
Stopper H, Schinzel R, Sebekova K, Heidland A. Genotoxicity of advanced glycation end products in mammalian cells. Cancer Lett 2003;190:151-156. (Pubitemid 36136013)
-
(2003)
Cancer Letters
, vol.190
, Issue.2
, pp. 151-156
-
-
Stopper, H.1
Schinzel, R.2
Sebekova, K.3
Heidland, A.4
-
126
-
-
44449097168
-
AGE-RAGE system and carcinogenesis
-
DOI 10.2174/138161208784139765
-
Abe R, Yamagishi S. AGE-RAGE system and carcinogenesis. Curr Pharm Des 2008;14:940-945. (Pubitemid 351753280)
-
(2008)
Current Pharmaceutical Design
, vol.14
, Issue.10
, pp. 940-945
-
-
Abe, R.1
Yamagishi, S.-I.2
-
127
-
-
0842286500
-
CD44 family and gynaecological cancer
-
Makrydimas G, Zagorianakou N, Zagorianakou P, Agnantis NJ. CD44 family and gynaecological cancer. In Vivo 2003;17: 633-640. (Pubitemid 38165466)
-
(2003)
Vivo
, vol.17
, Issue.6
, pp. 633-640
-
-
Makrydimas, G.1
Zagorianakou, N.2
Zagorianakou, P.3
Agnantis, N.J.4
-
128
-
-
53749085227
-
Increased soluble CD44 concentrations are associated with larger tumor size and lymph node metastasis in breast cancer patients
-
Mayer S, zur Hausen A, Watermann DO, Stamm S, Jager M, Gitsch G, Stickeler E. Increased soluble CD44 concentrations are associated with larger tumor size and lymph node metastasis in breast cancer patients. J Cancer Res Clin Oncol 2008;134:1229-1235.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 1229-1235
-
-
Mayer, S.1
Zur Hausen, A.2
Watermann, D.O.3
Stamm, S.4
Jager, M.5
Gitsch, G.6
Stickeler, E.7
-
129
-
-
44749091840
-
Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
-
Naor D, Wallach-Dayan SB, Zahalka MA, Sionov RV. Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol 2008;18:260-267.
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 260-267
-
-
Naor, D.1
Wallach-Dayan, S.B.2
Zahalka, M.A.3
Sionov, R.V.4
-
130
-
-
0027077553
-
Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation
-
Hale LP, Haynes BF. Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation. J Immunol 1992;149:3809-3816. (Pubitemid 23068859)
-
(1992)
Journal of Immunology
, vol.149
, Issue.12
, pp. 3809-3816
-
-
Hale, L.P.1
Haynes, B.F.2
-
131
-
-
0036046149
-
Bromelain treatment alters leukocyte expression of cell surface molecules involved in cellular adhesion and activation
-
DOI 10.1006/clim.2002.5254
-
Hale LP, Greer PK, Sempowski GD. Bromelain treatment alters leukocyte expression of cell surface molecules involved in cellular adhesion and activation. Clin Immunol 2002;104:183-190. (Pubitemid 35026228)
-
(2002)
Clinical Immunology
, vol.104
, Issue.2
, pp. 183-190
-
-
Hale, L.P.1
Greer, P.K.2
Sempowski, G.D.3
-
132
-
-
60249083774
-
Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro
-
Secor ER, Jr., Singh A, Guernsey LA, McNamara JT, Zhan L, Maulik N,Thrall RS. Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro. Int Immunopharmacol 2009;9:340-346.
-
(2009)
Int Immunopharmacol
, vol.9
, pp. 340-346
-
-
Secor Jr., E.R.1
Singh, A.2
Guernsey, L.A.3
McNamara, J.T.4
Zhan, L.5
Maulik, N.6
Thrall, R.S.7
-
133
-
-
45249083891
-
Bromelain treatment decreases neutrophil migration to sites of inflammation
-
Fitzhugh DJ, Shan S, Dewhirst MW, Hale LP. Bromelain treatment decreases neutrophil migration to sites of inflammation. Clin Immunol 2008;128:66-74.
-
(2008)
Clin Immunol
, vol.128
, pp. 66-74
-
-
Fitzhugh, D.J.1
Shan, S.2
Dewhirst, M.W.3
Hale, L.P.4
-
134
-
-
33745515023
-
Tumour microenvironment - TGFΒ: The molecular Jekyll and Hyde of cancer
-
DOI 10.1038/nrc1926, PII N1926
-
Bierie B, Moses HL. Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer 2006;6:506-520. (Pubitemid 43980540)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.7
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
135
-
-
0034918723
-
Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood
-
Desser L, Holomanova D, Zavadova E, Pavelka K, Mohr T, Herbacek I. Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood. Cancer Chemother Pharmacol 2001;47(Suppl.):S10-S15.
-
(2001)
Cancer Chemother Pharmacol
, vol.47
, Issue.SUPPL.
-
-
Desser, L.1
Holomanova, D.2
Zavadova, E.3
Pavelka, K.4
Mohr, T.5
Herbacek, I.6
-
136
-
-
33644819544
-
Dose-dependent induction of IL-6 by plant-derived proteases in vitro
-
Rose B, Herder C, Loffler H, Meierhoff G, Schloot NC, Walz M, Martin S. Dose-dependent induction of IL-6 by plant-derived proteases in vitro. Clin Exp Immunol 2006;143:85-92.
-
(2006)
Clin Exp Immunol
, vol.143
, pp. 85-92
-
-
Rose, B.1
Herder, C.2
Loffler, H.3
Meierhoff, G.4
Schloot, N.C.5
Walz, M.6
Martin, S.7
-
137
-
-
0035967625
-
Bromelain is an accelerator of phagocytosis, respiratory burst and Killing of Candida albicans by human granulocytes and monocytes
-
Brakebusch M, Wintergerst U, Petropoulou T, Notheis G, Husfeld L, Belohradsky BH, Adam D. Bromelain is an accelerator of phagocytosis, respiratory burst and Killing of Candida albicans by human granulocytes and monocytes. Eur J Med Res 2001;6:193-200.
-
(2001)
Eur J Med Res
, vol.6
, pp. 193-200
-
-
Brakebusch, M.1
Wintergerst, U.2
Petropoulou, T.3
Notheis, G.4
Husfeld, L.5
Belohradsky, B.H.6
Adam, D.7
-
138
-
-
43049124720
-
Signal cross talks for sustained MAPK activation and cell migration: The potential role of reactive oxygen species
-
Wu WS, Wu JR, Hu CT. Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species. Cancer Metastasis Rev 2008;27: 303-314.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 303-314
-
-
Wu, W.S.1
Wu, J.R.2
Hu, C.T.3
-
139
-
-
33845724468
-
Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
-
DOI 10.1016/j.freeradbiomed.2006.09.030, PII S0891584906006952
-
Fialkow L, Wang Y, Downey GP. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic Biol Med 2007;42:153-164. (Pubitemid 46001554)
-
(2007)
Free Radical Biology and Medicine
, vol.42
, Issue.2
, pp. 153-164
-
-
Fialkow, L.1
Wang, Y.2
Downey, G.P.3
-
140
-
-
40549119785
-
Soluble fibrin inhibits lymphocyte adherence and cytotoxicity against tumor cells: Implications for cancer metastasis and immunotherapy
-
DOI 10.1177/1076029607305619
-
Biggerstaff JP,WeidowB,Dexheimer J,Warnes G,Vidosh J, Patel S, Newman M, Patel P. Soluble fibrin inhibits lymphocyte adherence and cytotoxicity against tumor cells: implications for cancer metastasis and immunotherapy. Clin Appl Thromb Hemost 2008;14:193-202. (Pubitemid 351364015)
-
(2008)
Clinical and Applied Thrombosis/Hemostasis
, vol.14
, Issue.2
, pp. 193-202
-
-
Biggerstaff, J.P.1
Weidow, B.2
Dexheimer, J.3
Warnes, G.4
Vidosh, J.5
Patel, S.6
Newman, M.7
Patel, P.8
-
141
-
-
0034127606
-
Resistance of cancer cells to immune recognition and killing
-
DOI 10.1054/mehy.1999.0876
-
Lipinski B, Egyud LG. Resistance of cancer cells to immune recognition and killing. Med Hypotheses 2000;54:456-460. (Pubitemid 30204340)
-
(2000)
Medical Hypotheses
, vol.54
, Issue.3
, pp. 456-460
-
-
Lipinski, B.1
Egyud, L.G.2
-
142
-
-
48249157877
-
Beyond hemostasis: The role of platelets in inflammation, malignancy and infection
-
McNicol A, Israels SJ. Beyond hemostasis: the role of platelets in inflammation, malignancy and infection. CardiovascHematol Disord Drug Targets 2008;8:99-117.
-
(2008)
CardiovascHematol Disord Drug Targets
, vol.8
, pp. 99-117
-
-
McNicol, A.1
Israels, S.J.2
-
143
-
-
47249134658
-
Combination regimen with statins and NSAIDs: A promising strategy for cancer chemoprevention
-
Xiao H, Yang CS. Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. Int J Cancer 2008;123:983-990.
-
(2008)
Int J Cancer
, vol.123
, pp. 983-990
-
-
Xiao, H.1
Yang, C.S.2
-
144
-
-
33646469580
-
Aspirin and NSAIDs: Effects in breast and ovarian cancers
-
Crew KD, Neugut AI. Aspirin and NSAIDs: effects in breast and ovarian cancers. Curr Opin Obstet Gynecol 2006;18:71-75.
-
(2006)
Curr Opin Obstet Gynecol
, vol.18
, pp. 71-75
-
-
Crew, K.D.1
Neugut, A.I.2
|