메뉴 건너뛰기




Volumn 31, Issue 3, 2007, Pages 671-677

Evolution of the human MUC1 oncoprotein

Author keywords

Membrane bound mucins; MUC1; MUC2; MUC5B; MUC6; Secreted mucins; Transformation

Indexed keywords

CA 15-3 ANTIGEN; HYBRID PROTEIN; MUCIN; MUCIN 5B; MUCIN-5B; UNCLASSIFIED DRUG;

EID: 38449107133     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.31.3.671     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 0025834959 scopus 로고
    • Report on the first international work-shop on carcinoma-associated mucins
    • Taylor-Papadimitriou J: Report on the first international work-shop on carcinoma-associated mucins. Int J Cancer 49: 1-5, 1991.
    • (1991) Int J Cancer , vol.49 , pp. 1-5
    • Taylor-Papadimitriou, J.1
  • 3
    • 30044448792 scopus 로고    scopus 로고
    • Auto-proteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin
    • Macao B, Johansson DG, Hansson GC and Hard T: Auto-proteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin. Nat Struct Mol Biol 13: 71-76, 2006.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 71-76
    • Macao, B.1    Johansson, D.G.2    Hansson, G.C.3    Hard, T.4
  • 4
    • 25844434734 scopus 로고    scopus 로고
    • The MUC1 SEA module is a self-cleaving domain
    • Levitin F, Stern O, Weiss M, et al: The MUC1 SEA module is a self-cleaving domain. J Biol Chem 280: 33374-33386, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 33374-33386
    • Levitin, F.1    Stern, O.2    Weiss, M.3
  • 5
    • 0021740104 scopus 로고
    • Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
    • Kufe D, Inghirami G, Abe M, Hayes D, Justi-Wheeler H and Schlom J: Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 3: 223-232, 1984. (Pubitemid 15184701)
    • (1984) Hybridoma , vol.3 , Issue.3 , pp. 223-232
    • Kufe, D.1    Inghirami, G.2    Abe, M.3
  • 6
    • 0041850346 scopus 로고    scopus 로고
    • Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
    • Li Y, Liu D, Chen D, Kharbanda S and Kufe D: Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22: 6107-6110, 2003.
    • (2003) Oncogene , vol.22 , pp. 6107-6110
    • Li, Y.1    Liu, D.2    Chen, D.3    Kharbanda, S.4    Kufe, D.5
  • 7
    • 0042818006 scopus 로고    scopus 로고
    • Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
    • Yin L and Kufe D: Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J Biol Chem 278: 35458-35464, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 35458-35464
    • Yin, L.1    Kufe, D.2
  • 8
    • 10744220453 scopus 로고    scopus 로고
    • Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents
    • Ren J, Agata N, Chen D, et al: Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents. Cancer Cell 5: 163-175, 2004.
    • (2004) Cancer Cell , vol.5 , pp. 163-175
    • Ren, J.1    Agata, N.2    Chen, D.3
  • 9
    • 7944230166 scopus 로고    scopus 로고
    • MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress
    • DOI 10.1074/jbc.M408027200
    • Yin L, Huang L and Kufe D: MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem 279: 45721-45727, 2004. (Pubitemid 39491562)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.44 , pp. 45721-45727
    • Yin, L.1    Huang, L.2    Kufe, D.3
  • 10
    • 13844262819 scopus 로고    scopus 로고
    • Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
    • Wei X, Xu H and Kufe D: Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 7: 167-178, 2005.
    • (2005) Cancer Cell , vol.7 , pp. 167-178
    • Wei, X.1    Xu, H.2    Kufe, D.3
  • 11
    • 33846994065 scopus 로고    scopus 로고
    • Mucin 1 oncoprotein blocks hypoxia-inducible factor 1alpha activation in a survival response to hypoxia
    • Yin L, Kharbanda S and Kufe D: Mucin 1 oncoprotein blocks hypoxia-inducible factor 1alpha activation in a survival response to hypoxia. J Biol Chem 282: 257-266, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 257-266
    • Yin, L.1    Kharbanda, S.2    Kufe, D.3
  • 12
    • 33748055445 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage
    • DOI 10.1038/sj.emboj.7601263, PII 7601263
    • Raina D, Ahmad R, Kumar S, et al: MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage. EMBO J 25: 3774-3783, 2006. (Pubitemid 44300263)
    • (2006) EMBO Journal , vol.25 , Issue.16 , pp. 3774-3783
    • Raina, D.1    Ahmad, R.2    Kumar, S.3    Ren, J.4    Yoshida, K.5    Kharbanda, S.6    Kufe, D.7
  • 13
    • 0023741252 scopus 로고
    • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
    • Gendler S, Taylor-Papadimitriou J, Duhig T, Rothbard J and Burchell JA: A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J Biol Chem 263: 12820-12823, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 12820-12823
    • Gendler, S.1    Taylor-Papadimitriou, J.2    Duhig, T.3    Rothbard, J.4    Burchell, J.A.5
  • 14
    • 0024121580 scopus 로고
    • Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen
    • Siddiqui J, Abe M, Hayes D, Shani E, Yunis E and Kufe D: Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen. Proc Natl Acad Sci USA 85: 2320-2323, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2320-2323
    • Siddiqui, J.1    Abe, M.2    Hayes, D.3    Shani, E.4    Yunis, E.5    Kufe, D.6
  • 15
    • 0024834409 scopus 로고
    • DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer
    • Merlo G, Siddiqui J, Cropp C, et al: DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer. Cancer Res 49: 6966-6971, 1989.
    • (1989) Cancer Res , vol.49 , pp. 6966-6971
    • Merlo, G.1    Siddiqui, J.2    Cropp, C.3
  • 17
    • 11144240877 scopus 로고    scopus 로고
    • DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7
    • Li Y, Chen W, Ren J, et al: DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7. Cancer Biol Ther 2: 187-193, 2003.
    • (2003) Cancer Biol Ther , vol.2 , pp. 187-193
    • Li, Y.1    Chen, W.2    Ren, J.3
  • 18
    • 30744474431 scopus 로고    scopus 로고
    • MUC1 oncoprotein stabilizes and activates estrogen receptor alpha
    • Wei X, Xu H and Kufe D: MUC1 oncoprotein stabilizes and activates estrogen receptor alpha. Mol Cell 21: 295-305, 2006.
    • (2006) Mol Cell , vol.21 , pp. 295-305
    • Wei, X.1    Xu, H.2    Kufe, D.3
  • 19
    • 30044445260 scopus 로고    scopus 로고
    • MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90
    • Ren J, Bharti A, Raina D, Chen W, Ahmad R and Kufe D: MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90. Oncogene 25: 20-31, 2006.
    • (2006) Oncogene , vol.25 , pp. 20-31
    • Ren, J.1    Bharti, A.2    Raina, D.3    Chen, W.4    Ahmad, R.5    Kufe, D.6
  • 20
    • 28544448610 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin
    • Huang L, Chen D, Liu D, Yin L, Kharbanda S and Kufe D: MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin. Cancer Res 65: 10413-10422, 2005.
    • (2005) Cancer Res , vol.65 , pp. 10413-10422
    • Huang, L.1    Chen, D.2    Liu, D.3    Yin, L.4    Kharbanda, S.5    Kufe, D.6
  • 21
    • 0031723707 scopus 로고    scopus 로고
    • Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma- Associated antigen and β-catenin
    • Li Y, Bharti A, Chen D, Gong J and Kufe D: Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin. Mol Cell Biol 18: 7216-7224, 1998. (Pubitemid 28533041)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.12 , pp. 7216-7224
    • Li, Y.1    Bharti, A.2    Chen, D.3    Gong, J.4    Kufe, D.5
  • 22
    • 0035794215 scopus 로고    scopus 로고
    • The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin
    • Li Y, Kuwahara H, Ren J, Wen G and Kufe D: The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin. J Biol Chem 276: 6061-6064, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 6061-6064
    • Li, Y.1    Kuwahara, H.2    Ren, J.3    Wen, G.4    Kufe, D.5
  • 23
    • 0037124099 scopus 로고    scopus 로고
    • Protein kinase C β regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling
    • DOI 10.1074/jbc.M200436200
    • Ren J, Li Y and Kufe D: Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling. J Biol Chem 277: 17616-17622, 2002. (Pubitemid 34967564)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.20 , pp. 17616-17622
    • Ren, J.1    Li, Y.2    Kufe, D.3
  • 25
    • 33646265264 scopus 로고    scopus 로고
    • Distinct evolution of the human carcinoma-associated transmembrane mucins, MUC1, MUC4 and MUC16
    • Duraisamy S, Ramasamy S, Kharbanda S and Kufe D: Distinct evolution of the human carcinoma-associated transmembrane mucins, MUC1, MUC4 AND MUC16. Gene 373: 28-34, 2006.
    • (2006) Gene , vol.373 , pp. 28-34
    • Duraisamy, S.1    Ramasamy, S.2    Kharbanda, S.3    Kufe, D.4
  • 27
    • 0032568655 scopus 로고    scopus 로고
    • SMART, a simple modular architecture research tool: Identification of signaling domains
    • Schultz J, Milpetz F, Bork P and Ponting CP: SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci USA 95: 5857-5864, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5857-5864
    • Schultz, J.1    Milpetz, F.2    Bork, P.3    Ponting, C.P.4
  • 29
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG and Gibson TJ: CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680, 1994.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 30
    • 0000122573 scopus 로고
    • PHYLIP-Phylogeny Inference Package
    • Version 3.2
    • Felsenstein J: PHYLIP-Phylogeny Inference Package (Version 3.2). Cladistics 5: 164-166, 1989.
    • (1989) Cladistics , vol.5 , pp. 164-166
    • Felsenstein, J.1
  • 31
    • 0030203863 scopus 로고    scopus 로고
    • TreeView: An application to display phylogenetic trees on personal computers
    • Page R: TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12: 357-358, 1996.
    • (1996) Comput Appl Biosci , vol.12 , pp. 357-358
    • Page, R.1
  • 32
    • 0029013157 scopus 로고
    • The SEA module: A new extracellular domain associated with O-glycosylation
    • Bork P and Patthy L: The SEA module: a new extracellular domain associated with O-glycosylation. Protein Sci 4: 1421-1425, 1995.
    • (1995) Protein Sci , vol.4 , pp. 1421-1425
    • Bork, P.1    Patthy, L.2
  • 34
    • 0032522156 scopus 로고    scopus 로고
    • Structure and organization of the RBMY genes on the human Y chromosome: Transposition and amplification of an ancestral autosomal hnRNPG gene
    • Chai NN, Zhou H, Hernandez J, Najmabadi H, Bhasin S and Yen PH: Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene. Genomics 49: 283-289, 1998.
    • (1998) Genomics , vol.49 , pp. 283-289
    • Chai, N.N.1    Zhou, H.2    Hernandez, J.3    Najmabadi, H.4    Bhasin, S.5    Yen, P.H.6
  • 35
    • 0033180125 scopus 로고    scopus 로고
    • Human KRML (MAFB): CDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias
    • DOI 10.1006/geno.1999.5884
    • Wang PW, Eisenbart JD, Cordes SP, Barsh GS, Stoffel M and Le Beau MM: Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. Genomics 59: 275-281, 1999. (Pubitemid 29406908)
    • (1999) Genomics , vol.59 , Issue.3 , pp. 275-281
    • Wang, P.W.1    Eisenbart, J.D.2    Cordes, S.P.3    Barsh, G.S.4    Stoffel, M.5    Le Beau, M.M.6
  • 36
    • 0035958015 scopus 로고    scopus 로고
    • Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro
    • Nagase T, Nakayama M, Nakajima D, Kikuno R and Ohara O: Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res 8: 85-95, 2001. (Pubitemid 33617355)
    • (2001) DNA Research , vol.8 , Issue.2 , pp. 85-95
    • Nagase, T.1    Nakayama, M.2    Nakajima, D.3    Kikuno, R.4    Ohara, O.5
  • 37
    • 0034948819 scopus 로고    scopus 로고
    • Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
    • Donoviel DB, Freed DD, Vogel H, et al: Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol 21: 4829-4836, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 4829-4836
    • Donoviel, D.B.1    Freed, D.D.2    Vogel, H.3
  • 38
    • 0029891787 scopus 로고    scopus 로고
    • Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae
    • Law SF, Estojak J, Wang B, Mysliwiec T, Kruh G and Golemis EA: Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol Cell Biol 16: 3327-3337, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 3327-3337
    • Law, S.F.1    Estojak, J.2    Wang, B.3    Mysliwiec, T.4    Kruh, G.5    Golemis, E.A.6
  • 39
    • 0029148591 scopus 로고
    • Role of IRS-2 in insulin and cytokine signalling
    • Sun XJ, Wang LM, Zhang Y, et al: Role of IRS-2 in insulin and cytokine signalling. Nature 377: 173-177, 1995.
    • (1995) Nature , vol.377 , pp. 173-177
    • Sun, X.J.1    Wang, L.M.2    Zhang, Y.3
  • 40
    • 0031023179 scopus 로고    scopus 로고
    • Human mucin gene MUC5B, the 10.7-kb Large central exon encodes various alternate subdomains resulting in a super-repeat. Structural evidence for a 11p15.5 gene family
    • DOI 10.1074/jbc.272.6.3168
    • Desseyn JL, Guyonnet-Duperat V, Porchet N, Aubert JP and Laine A: Human mucin gene MUC5B, the 10.7-kb large central exon encodes various alternate subdomains resulting in a super-repeat. Structural evidence for a 11p15.5 gene family. J Biol Chem 272: 3168-3178, 1997. (Pubitemid 27066804)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.6 , pp. 3168-3178
    • Desseyn, J.-L.1    Guyonnet-Duperat, V.2    Porchet, N.3    Aubert, J.-P.4    Laine, A.5
  • 41
    • 0030589589 scopus 로고    scopus 로고
    • Human mucin genes assigned to 11p15.5: Identification and organization of a cluster of genes
    • Pigny P, Guyonnet-Duperat V, Hill AS, et al: Human mucin genes assigned to 11p15.5: identification and organization of a cluster of genes. Genomics 38: 340-352, 1996.
    • (1996) Genomics , vol.38 , pp. 340-352
    • Pigny, P.1    Guyonnet-Duperat, V.2    Hill, A.S.3
  • 44
    • 79960815298 scopus 로고    scopus 로고
    • MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation
    • Huang L, Ren J, Chen D, Li Y, Kharbanda S and Kufe D: MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation. Cancer Biol Ther 2: 702-706, 2003.
    • (2003) Cancer Biol Ther , vol.2 , pp. 702-706
    • Huang, L.1    Ren, J.2    Chen, D.3    Li, Y.4    Kharbanda, S.5    Kufe, D.6
  • 45
    • 0035805568 scopus 로고    scopus 로고
    • Aberrant expression of human mucin gene MUC5B in gastric carcinoma and cancer cells. Identification and regulation of a distal promoter
    • Perrais M, Pigny P, Buisine MP, Porchet N, Aubert JP and van Seuningen-Lempire I: Aberrant expression of human mucin gene MUC5B in gastric carcinoma and cancer cells. Identification and regulation of a distal promoter. J Biol Chem 276: 15386-15396, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 15386-15396
    • Perrais, M.1    Pigny, P.2    Buisine, M.P.3    Porchet, N.4    Aubert, J.P.5    Van Seuningen-Lempire, I.6
  • 46
    • 33344464417 scopus 로고    scopus 로고
    • Immunohistochemical analysis of MUC5B apomucin expression in breast cancer and non-malignant breast tissues
    • Sonora C, Mazal D, Berois N, et al: Immunohistochemical analysis of MUC5B apomucin expression in breast cancer and non-malignant breast tissues. J Histochem Cytochem 54: 289-299, 2006.
    • (2006) J Histochem Cytochem , vol.54 , pp. 289-299
    • Sonora, C.1    Mazal, D.2    Berois, N.3
  • 47
    • 0030958706 scopus 로고    scopus 로고
    • Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β- Catenin in cell adhesion
    • DOI 10.1074/jbc.272.19.12492
    • Yamamoto M, Bharti A, Li Y and Kufe D: Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion. J Biol Chem 272: 12492-12494, 1997. (Pubitemid 27203339)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.19 , pp. 12492-12494
    • Yamamoto, M.1    Bharti, A.2    Li, Y.3    Kufe, D.4
  • 48
    • 0842288993 scopus 로고    scopus 로고
    • Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells
    • Li Q, Ren J and Kufe D: Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells. Biochem Biophys Res Commun 315: 471-476, 2004.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 471-476
    • Li, Q.1    Ren, J.2    Kufe, D.3
  • 49
    • 33747757995 scopus 로고    scopus 로고
    • An inventory of mucin genes in the chicken genome shows that the mucin domain of Muc13 is encoded by multiple exons and that ovomucin is part of a locus of related gel-forming mucins
    • Lang T, Hansson GC and Samuelsson T: An inventory of mucin genes in the chicken genome shows that the mucin domain of Muc13 is encoded by multiple exons and that ovomucin is part of a locus of related gel-forming mucins. BMC Genomics 7: 197, 2006.
    • (2006) BMC Genomics , vol.7 , pp. 197
    • Lang, T.1    Hansson, G.C.2    Samuelsson, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.