-
1
-
-
0033104495
-
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
-
M. Asada, T. Yamada, H. Ichijo, D. Delia, K. Miyazono, K. Fukumuro, and S. Mizutani Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation EMBO J. 18 1999 1223 1234
-
(1999)
EMBO J.
, vol.18
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
Delia, D.4
Miyazono, K.5
Fukumuro, K.6
Mizutani, S.7
-
2
-
-
0035694469
-
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
-
N.A. Barlev, L. Liu, N.H. Chehab, K. Mansfield, K.G. Harris, T.D. Halazonetis, and S.L. Berger Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases Mol. Cell 8 2001 1243 1254
-
(2001)
Mol. Cell
, vol.8
, pp. 1243-1254
-
-
Barlev, N.A.1
Liu, L.2
Chehab, N.H.3
Mansfield, K.4
Harris, K.G.5
Halazonetis, T.D.6
Berger, S.L.7
-
3
-
-
0032832195
-
Physical and functional interaction between p53 and the Werner's syndrome protein
-
G. Blander, J. Kipnis, J.F. Leal, C.E. Yu, G.D. Schellenberg, and M. Oren Physical and functional interaction between p53 and the Werner's syndrome protein J. Biol. Chem. 274 1999 29463 29469
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29463-29469
-
-
Blander, G.1
Kipnis, J.2
Leal, J.F.3
Yu, C.E.4
Schellenberg, G.D.5
Oren, M.6
-
4
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
F. Bunz, A. Dutriaux, C. Lengauer, T. Waldman, S. Zhou, J.P. Brown, J.M. Sedivy, K.W. Kinzler, and B. Vogelstein Requirement for p53 and p21 to sustain G2 arrest after DNA damage Science 282 1998 1497 1501
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
5
-
-
0028812627
-
Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein
-
J. Chang, D.H. Kim, S.W. Lee, K.Y. Choi, and Y.C. Sung Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein J. Biol. Chem. 270 1995 25014 25019
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25014-25019
-
-
Chang, J.1
Kim, D.H.2
Lee, S.W.3
Choi, K.Y.4
Sung, Y.C.5
-
6
-
-
0034665461
-
P53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage
-
C. Chao, S. Saito, J. Kang, C.W. Anderson, E. Appella, and Y. Xu p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage EMBO J. 19 2000 4967 4975
-
(2000)
EMBO J.
, vol.19
, pp. 4967-4975
-
-
Chao, C.1
Saito, S.2
Kang, J.3
Anderson, C.W.4
Appella, E.5
Xu, Y.6
-
7
-
-
0033151867
-
Excess beta-catenin promotes accumulation of transcriptionally active p53
-
A. Damalas, A. Ben-Ze'ev, I. Simcha, M. Shtutman, J.F. Leal, J. Zhurinsky, B. Geiger, and M. Oren Excess beta-catenin promotes accumulation of transcriptionally active p53 EMBO J. 18 1999 3054 3063
-
(1999)
EMBO J.
, vol.18
, pp. 3054-3063
-
-
Damalas, A.1
Ben-Ze'Ev, A.2
Simcha, I.3
Shtutman, M.4
Leal, J.F.5
Zhurinsky, J.6
Geiger, B.7
Oren, M.8
-
8
-
-
0035801388
-
Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation
-
A. Damalas, S. Kahan, M. Shtutman, A. Ben-Ze'ev, and M. Oren Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation EMBO J. 20 2001 4912 4922
-
(2001)
EMBO J.
, vol.20
, pp. 4912-4922
-
-
Damalas, A.1
Kahan, S.2
Shtutman, M.3
Ben-Ze'Ev, A.4
Oren, M.5
-
9
-
-
0242572066
-
Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells
-
Y. Dong, S.L. Chi, A.D. Borowsky, Y. Fan, and R.H. Weiss Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells Cell. Signal. 16 2004 263 269
-
(2004)
Cell. Signal.
, vol.16
, pp. 263-269
-
-
Dong, Y.1
Chi, S.L.2
Borowsky, A.D.3
Fan, Y.4
Weiss, R.H.5
-
10
-
-
0033572746
-
Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
-
N. Dumaz, and D.W. Meek Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2 EMBO J. 18 1999 7002 7010
-
(1999)
EMBO J.
, vol.18
, pp. 7002-7010
-
-
Dumaz, N.1
Meek, D.W.2
-
11
-
-
0141844609
-
The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells
-
J. Dupont, M. Karas, and D. LeRoith The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells J. Biol. Chem. 278 2003 37256 37264
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37256-37264
-
-
Dupont, J.1
Karas, M.2
Leroith, D.3
-
12
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
W.S. El-Deiry, T. Tokino, V.E. Velculescu, D.B. Levy, R. Parsons, J.M. Trent, D. Lin, W.E. Mercer, K.W. Kinzler, and B. Vogelstein WAF1, a potential mediator of p53 tumor suppression Cell 75 1993 817 825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
13
-
-
0034881964
-
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
-
J.M. Espinosa, and B.M. Emerson Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment Mol. Cell 8 2001 57 69
-
(2001)
Mol. Cell
, vol.8
, pp. 57-69
-
-
Espinosa, J.M.1
Emerson, B.M.2
-
14
-
-
0242329884
-
P53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage
-
J.M. Espinosa, R.E. Verdun, and B.M. Emerson p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage Mol. Cell 12 2003 1015 1027
-
(2003)
Mol. Cell
, vol.12
, pp. 1015-1027
-
-
Espinosa, J.M.1
Verdun, R.E.2
Emerson, B.M.3
-
15
-
-
0029943611
-
Functional interaction between p53, the TATA-binding protein (TBP), and TBP-associated factors in vivo
-
G. Farmer, J. Colgan, Y. Nakatani, J.L. Manley, and C. Prives Functional interaction between p53, the TATA-binding protein (TBP), and TBP-associated factors in vivo Mol. Cell. Biol. 16 1996 4295 4304
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4295-4304
-
-
Farmer, G.1
Colgan, J.2
Nakatani, Y.3
Manley, J.L.4
Prives, C.5
-
16
-
-
0037041392
-
P63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
E.R. Flores, K.Y. Tsai, D. Crowley, S. Sengupta, A. Yang, F. McKeon, and T. Jacks p63 and p73 are required for p53-dependent apoptosis in response to DNA damage Nature 416 2002 560 564
-
(2002)
Nature
, vol.416
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
17
-
-
0023741252
-
A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
-
S. Gendler, J. Taylor-Papadimitriou, T. Duhig, J. Rothbard, and J.A. Burchell A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats J. Biol. Chem. 263 1988 12820 12823
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 12820-12823
-
-
Gendler, S.1
Taylor-Papadimitriou, J.2
Duhig, T.3
Rothbard, J.4
Burchell, J.A.5
-
18
-
-
0028908796
-
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
-
N. Horikoshi, A. Usheva, J. Chen, A.J. Levine, R. Weinmann, and T. Shenk Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression Mol. Cell. Biol. 15 1995 227 234
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 227-234
-
-
Horikoshi, N.1
Usheva, A.2
Chen, J.3
Levine, A.J.4
Weinmann, R.5
Shenk, T.6
-
19
-
-
0036132647
-
Novel function of the cyclin a binding site of E2F in regulating p53-induced apoptosis in response to DNA damage
-
J.K. Hsieh, D. Yap, D.J. O'Connor, V. Fogal, L. Fallis, F. Chan, S. Zhong, and X. Lu Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage Mol. Cell. Biol. 22 2002 78 93
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 78-93
-
-
Hsieh, J.K.1
Yap, D.2
O'Connor, D.J.3
Fogal, V.4
Fallis, L.5
Chan, F.6
Zhong, S.7
Lu, X.8
-
20
-
-
79960815298
-
MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation
-
L. Huang, J. Ren, D. Chen, Y. Li, S. Kharbanda, and D. Kufe MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation Cancer Biol. Ther. 2 2003 702 706
-
(2003)
Cancer Biol. Ther.
, vol.2
, pp. 702-706
-
-
Huang, L.1
Ren, J.2
Chen, D.3
Li, Y.4
Kharbanda, S.5
Kufe, D.6
-
21
-
-
0037162506
-
Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response
-
M.T. Jack, R.A. Woo, A. Hirao, A. Cheung, T.W. Mak, and P.W. Lee Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response Proc. Natl. Acad. Sci. USA 99 2002 9825 9829
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9825-9829
-
-
Jack, M.T.1
Woo, R.A.2
Hirao, A.3
Cheung, A.4
Mak, T.W.5
Lee, P.W.6
-
22
-
-
0030900605
-
Identification of redox/repair protein Ref-1 as a potent activator of p53
-
L. Jayaraman, K.G. Murthy, C. Zhu, T. Curran, S. Xanthoudakis, and C. Prives Identification of redox/repair protein Ref-1 as a potent activator of p53 Genes Dev. 11 1997 558 570
-
(1997)
Genes Dev.
, vol.11
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.G.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
23
-
-
0033821977
-
A transactivation-deficient mouse model provides insights into Trp53 regulation and function
-
G.S. Jimenez, M. Nister, J.M. Stommel, M. Beeche, E.A. Barcarse, X.Q. Zhang, S. O'Gorman, and G.M. Wahl A transactivation-deficient mouse model provides insights into Trp53 regulation and function Nat. Genet. 26 2000 37 43
-
(2000)
Nat. Genet.
, vol.26
, pp. 37-43
-
-
Jimenez, G.S.1
Nister, M.2
Stommel, J.M.3
Beeche, M.4
Barcarse, E.A.5
Zhang, X.Q.6
O'Gorman, S.7
Wahl, G.M.8
-
24
-
-
0037039319
-
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
-
M.D. Kaeser, and R.D. Iggo Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo Proc. Natl. Acad. Sci. USA 99 2002 95 100
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 95-100
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
25
-
-
1042278767
-
Nuclear transport and cancer: From mechanism to intervention
-
T.R. Kau, J.C. Way, and P.A. Silver Nuclear transport and cancer: From mechanism to intervention Nat. Rev. Cancer 4 2004 106 117
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 106-117
-
-
Kau, T.R.1
Way, J.C.2
Silver, P.A.3
-
26
-
-
0029098225
-
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents
-
S. Kharbanda, R. Ren, P. Pandey, T.D. Shafman, S.M. Feller, R.R. Weichselbaum, and D.W. Kufe Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents Nature 376 1995 785 788
-
(1995)
Nature
, vol.376
, pp. 785-788
-
-
Kharbanda, S.1
Ren, R.2
Pandey, P.3
Shafman, T.D.4
Feller, S.M.5
Weichselbaum, R.R.6
Kufe, D.W.7
-
27
-
-
0021740104
-
Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
-
D. Kufe, G. Inghirami, M. Abe, D. Hayes, H. Justi-Wheeler, and J. Schlom Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors Hybridoma 3 1984 223 232
-
(1984)
Hybridoma
, vol.3
, pp. 223-232
-
-
Kufe, D.1
Inghirami, G.2
Abe, M.3
Hayes, D.4
Justi-Wheeler, H.5
Schlom, J.6
-
28
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
P.F. Lambert, F. Kashanchi, M.F. Radonovich, R. Shiekhattar, and J.N. Brady Phosphorylation of p53 serine 15 increases interaction with CBP J. Biol. Chem. 273 1998 33048 33053
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
29
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
A.J. Levine p53, the cellular gatekeeper for growth and division Cell 88 1997 323 331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
30
-
-
0031723707
-
Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin
-
Y. Li, A. Bharti, D. Chen, J. Gong, and D. Kufe Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin Mol. Cell. Biol. 18 1998 7216 7224
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7216-7224
-
-
Li, Y.1
Bharti, A.2
Chen, D.3
Gong, J.4
Kufe, D.5
-
31
-
-
0035794215
-
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin
-
Y. Li, H. Kuwahara, J. Ren, G. Wen, and D. Kufe The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin J. Biol. Chem. 276 2001 6061 6064
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6061-6064
-
-
Li, Y.1
Kuwahara, H.2
Ren, J.3
Wen, G.4
Kufe, D.5
-
32
-
-
0035929643
-
The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin
-
Y. Li, J. Ren, W.-H. Yu, G. Li, H. Kuwahara, L. Yin, K.L. Carraway, and D. Kufe The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin J. Biol. Chem. 276 2001 35239 35242
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35239-35242
-
-
Li, Y.1
Ren, J.2
Yu, W.-H.3
Li, G.4
Kuwahara, H.5
Yin, L.6
Carraway, K.L.7
Kufe, D.8
-
33
-
-
11144240877
-
DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7
-
Y. Li, W. Chen, J. Ren, W. Yu, Q. Li, K. Yoshida, and D. Kufe DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7 Cancer Biol. Ther. 2 2003 187 193
-
(2003)
Cancer Biol. Ther.
, vol.2
, pp. 187-193
-
-
Li, Y.1
Chen, W.2
Ren, J.3
Yu, W.4
Li, Q.5
Yoshida, K.6
Kufe, D.7
-
34
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
Y. Li, D. Liu, D. Chen, S. Kharbanda, and D. Kufe Human DF3/MUC1 carcinoma-associated protein functions as an oncogene Oncogene 22 2003 6107 6110
-
(2003)
Oncogene
, vol.22
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
Kharbanda, S.4
Kufe, D.5
-
35
-
-
0041828907
-
Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein
-
Y. Li, W.-H. Yu, J. Ren, L. Huang, S. Kharbanda, M. Loda, and D. Kufe Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein Mol. Cancer Res. 1 2003 765 775
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 765-775
-
-
Li, Y.1
Yu, W.-H.2
Ren, J.3
Huang, L.4
Kharbanda, S.5
Loda, M.6
Kufe, D.7
-
36
-
-
0026733662
-
Cell-associated episialin is a complex containing two proteins derived from a common precursor
-
M.J. Ligtenberg, L. Kruijshaar, F. Buijs, M. van Meijer, S.V. Litvinov, and J. Hilkens Cell-associated episialin is a complex containing two proteins derived from a common precursor J. Biol. Chem. 267 1992 6171 6177
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 6171-6177
-
-
Ligtenberg, M.J.1
Kruijshaar, L.2
Buijs, F.3
Van Meijer, M.4
Litvinov, S.V.5
Hilkens, J.6
-
37
-
-
0027316149
-
The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription
-
X. Liu, C.W. Miller, P.H. Koeffler, and A.J. Berk The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription Mol. Cell. Biol. 13 1993 3291 3300
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3291-3300
-
-
Liu, X.1
Miller, C.W.2
Koeffler, P.H.3
Berk, A.J.4
-
38
-
-
0038269028
-
The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein
-
G. Liu, T. Xia, and X. Chen The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein J. Biol. Chem. 278 2003 17557 17565
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17557-17565
-
-
Liu, G.1
Xia, T.2
Chen, X.3
-
39
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
T.K. MacLachlan, R. Takimoto, and W.S. El-Deiry BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets Mol. Cell. Biol. 22 2002 4280 4292
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
40
-
-
0024834409
-
DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer
-
G. Merlo, J. Siddiqui, C. Cropp, D.S. Liscia, R. Lidereau, R. Callahan, and D. Kufe DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer Cancer Res. 49 1989 6966 6971
-
(1989)
Cancer Res.
, vol.49
, pp. 6966-6971
-
-
Merlo, G.1
Siddiqui, J.2
Cropp, C.3
Liscia, D.S.4
Lidereau, R.5
Callahan, R.6
Kufe, D.7
-
41
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
T. Miyashita, and J.C. Reed Tumor suppressor p53 is a direct transcriptional activator of the human bax gene Cell 80 1995 293 299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
42
-
-
10744233648
-
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation
-
S. Mujtaba, Y. He, L. Zeng, S. Yan, O. Plotnikova, R. Sanchez, N.J. Zeleznik-Le, Z. Ronai, and M.M. Zhou Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation Mol. Cell 13 2004 251 263
-
(2004)
Mol. Cell
, vol.13
, pp. 251-263
-
-
Mujtaba, S.1
He, Y.2
Zeng, L.3
Yan, S.4
Plotnikova, O.5
Sanchez, R.6
Zeleznik-Le, N.J.7
Ronai, Z.8
Zhou, M.M.9
-
43
-
-
0031743648
-
P53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
M. Muller, S. Wilder, D. Bannasch, D. Israeli, K. Lehlbach, M. Li-Weber, S.L. Friedman, P.R. Galle, W. Stremmel, M. Oren, and P.H. Krammer p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs J. Exp. Med. 188 1998 2033 2045
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedman, S.L.7
Galle, P.R.8
Stremmel, W.9
Oren, M.10
Krammer, P.H.11
-
44
-
-
0033985661
-
Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization
-
Y. Nie, H. Li, C. Bula, and X. Liu Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization Mol. Cell. Biol. 20 2000 741 748
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 741-748
-
-
Nie, Y.1
Li, H.2
Bula, C.3
Liu, X.4
-
45
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
E. Oda, R. Ohki, H. Murasawa, J. Nemoto, T. Shibue, T. Yamashita, T. Tokino, T. Taniguchi, and N. Tanaka Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis Science 288 2000 1053 1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
46
-
-
0034664733
-
P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
K. Oda, H. Arakawa, T. Tanaka, K. Matsuda, C. Tanikawa, T. Mori, H. Nishimori, K. Tamai, T. Tokino, Y. Nakamura, and Y. Taya p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53 Cell 102 2000 849 862
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
Nishimori, H.7
Tamai, K.8
Tokino, T.9
Nakamura, Y.10
Taya, Y.11
-
47
-
-
0038075338
-
Decision making by p53: Life, death and cancer
-
M. Oren Decision making by p53: Life, death and cancer Cell Death Differ. 10 2003 431 442
-
(2003)
Cell Death Differ.
, vol.10
, pp. 431-442
-
-
Oren, M.1
-
48
-
-
0026659195
-
Tumor selective reactivity of a monoclonal antibody prepared against a recombinant peptide derived from the DF3 human breast carcinoma-associated antigen
-
L. Perey, D.F. Hayes, P. Maimonis, M. Abe, C. O'Hara, and D.W. Kufe Tumor selective reactivity of a monoclonal antibody prepared against a recombinant peptide derived from the DF3 human breast carcinoma-associated antigen Cancer Res. 52 1992 2563 2568
-
(1992)
Cancer Res.
, vol.52
, pp. 2563-2568
-
-
Perey, L.1
Hayes, D.F.2
Maimonis, P.3
Abe, M.4
O'Hara, C.5
Kufe, D.W.6
-
49
-
-
0037072483
-
P73β is regulated by protein kinase Cδ catalytic fragment generated in the apoptotic response to DNA damage
-
J. Ren, R. Datta, H. Shioya, Y. Li, E. Oki, V. Biedermann, A. Bharti, and D. Kufe p73β is regulated by protein kinase Cδ catalytic fragment generated in the apoptotic response to DNA damage J. Biol. Chem. 277 2002 33758 33765
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33758-33765
-
-
Ren, J.1
Datta, R.2
Shioya, H.3
Li, Y.4
Oki, E.5
Biedermann, V.6
Bharti, A.7
Kufe, D.8
-
50
-
-
0037124099
-
Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling
-
J. Ren, Y. Li, and D. Kufe Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling J. Biol. Chem. 277 2002 17616 17622
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17616-17622
-
-
Ren, J.1
Li, Y.2
Kufe, D.3
-
51
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents
-
J. Ren, N. Agata, D. Chen, Y. Li, W.-H. Yu, L. Huang, D. Raina, W. Chen, S. Kharbanda, and D. Kufe Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents Cancer Cell 5 2004 163 175
-
(2004)
Cancer Cell
, vol.5
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
Li, Y.4
Yu, W.-H.5
Huang, L.6
Raina, D.7
Chen, W.8
Kharbanda, S.9
Kufe, D.10
-
53
-
-
17944379798
-
ASPP proteins specifically stimulate the apoptotic function of p53
-
Y. Samuels-Lev, D.J. O'Connor, D. Bergamaschi, G. Trigiante, J.K. Hsieh, S. Zhong, I. Campargue, L. Naumovski, T. Crook, and X. Lu ASPP proteins specifically stimulate the apoptotic function of p53 Mol. Cell 8 2001 781 794
-
(2001)
Mol. Cell
, vol.8
, pp. 781-794
-
-
Samuels-Lev, Y.1
O'Connor, D.J.2
Bergamaschi, D.3
Trigiante, G.4
Hsieh, J.K.5
Zhong, S.6
Campargue, I.7
Naumovski, L.8
Crook, T.9
Lu, X.10
-
54
-
-
0035918199
-
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
-
J. Schroeder, M. Thompson, M. Gardner, and S. Gendler Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland J. Biol. Chem. 276 2001 13057 13064
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13057-13064
-
-
Schroeder, J.1
Thompson, M.2
Gardner, M.3
Gendler, S.4
-
55
-
-
4143099166
-
MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation
-
J.A. Schroeder, A.A. Masri, M.C. Adriance, J.C. Tessier, K.L. Kotlarczyk, M.C. Thompson, and S.J. Gendler MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation Oncogene 23 2004 5739 5747
-
(2004)
Oncogene
, vol.23
, pp. 5739-5747
-
-
Schroeder, J.A.1
Masri, A.A.2
Adriance, M.C.3
Tessier, J.C.4
Kotlarczyk, K.L.5
Thompson, M.C.6
Gendler, S.J.7
-
56
-
-
0027050648
-
Wild-type p53 binds to the TATA-binding protein and represses transcription
-
E. Seto, A. Usheva, G. Zambett, J. Momand, R. Horikoshi, A. Weinmann, J. Levine, and T. Shenk Wild-type p53 binds to the TATA-binding protein and represses transcription Proc. Natl. Acad. Sci. USA 89 1992 12028 12032
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 12028-12032
-
-
Seto, E.1
Usheva, A.2
Zambett, G.3
Momand, J.4
Horikoshi, R.5
Weinmann, A.6
Levine, J.7
Shenk, T.8
-
57
-
-
0033637703
-
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
-
Y. Shang, X. Hu, J. DiRenzo, M.A. Lazar, and M. Brown Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription Cell 103 2000 843 852
-
(2000)
Cell
, vol.103
, pp. 843-852
-
-
Shang, Y.1
Hu, X.2
Direnzo, J.3
Lazar, M.A.4
Brown, M.5
-
58
-
-
0033197703
-
A novel cofactor for p300 that regulates the p53 response
-
N. Shikama, C. Lee, S. France, L. Delavaine, J. Lyon, M. Krstic-Demonacos, and N. La Thangue A novel cofactor for p300 that regulates the p53 response Mol. Cell 4 1999 365 376
-
(1999)
Mol. Cell
, vol.4
, pp. 365-376
-
-
Shikama, N.1
Lee, C.2
France, S.3
Delavaine, L.4
Lyon, J.5
Krstic-Demonacos, M.6
La Thangue, N.7
-
59
-
-
0024121580
-
Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen
-
J. Siddiqui, M. Abe, D. Hayes, E. Shani, E. Yunis, and D. Kufe Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen Proc. Natl. Acad. Sci. USA 85 1988 2320 2323
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 2320-2323
-
-
Siddiqui, J.1
Abe, M.2
Hayes, D.3
Shani, E.4
Yunis, E.5
Kufe, D.6
-
60
-
-
0033151615
-
P53-mediated apoptosis is attenuated in Werner syndrome cells
-
E.A. Spillare, A.I. Robles, X.W. Wang, J.C. Shen, C.E. Yu, G.D. Schellenberg, and C.C. Harris p53-mediated apoptosis is attenuated in Werner syndrome cells Genes Dev. 13 1999 1355 1360
-
(1999)
Genes Dev.
, vol.13
, pp. 1355-1360
-
-
Spillare, E.A.1
Robles, A.I.2
Wang, X.W.3
Shen, J.C.4
Yu, C.E.5
Schellenberg, G.D.6
Harris, C.C.7
-
61
-
-
0035028599
-
Kinetics of p53 binding to promoter sites in vivo
-
S.T. Szak, D. Mays, and J.A. Pietenpol Kinetics of p53 binding to promoter sites in vivo Mol. Cell. Biol. 21 2001 3375 3386
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3375-3386
-
-
Szak, S.T.1
Mays, D.2
Pietenpol, J.A.3
-
62
-
-
0037456842
-
Segregation of receptor and ligand regulates activation of epithelial growth factor receptor
-
P.D. Vermeer, L.A. Einwalter, T.O. Moninger, T. Rokhlina, J.A. Kern, J. Zabner, and M.J. Welsh Segregation of receptor and ligand regulates activation of epithelial growth factor receptor Nature 422 2003 322 326
-
(2003)
Nature
, vol.422
, pp. 322-326
-
-
Vermeer, P.D.1
Einwalter, L.A.2
Moninger, T.O.3
Rokhlina, T.4
Kern, J.A.5
Zabner, J.6
Welsh, M.J.7
-
63
-
-
0036674617
-
Live or let die: The cell's response to p53
-
K.H. Vousden, and X. Lu Live or let die: The cell's response to p53 Nat. Rev. Cancer 2 2002 594 604
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
64
-
-
0035195557
-
The evolution of diverse biological responses to DNA damage: Insights from yeast and p53
-
G.M. Wahl, and A.M. Carr The evolution of diverse biological responses to DNA damage: Insights from yeast and p53 Nat. Cell Biol. 3 2001 E277 E286
-
(2001)
Nat. Cell Biol.
, vol.3
-
-
Wahl, G.M.1
Carr, A.M.2
-
65
-
-
0035890271
-
HADA3 is required for p53 activity
-
T. Wang, T. Kobayashi, R. Takimoto, A.E. Denes, E.L. Snyder, W.S. el-Deiry, and R.K. Brachmann hADA3 is required for p53 activity EMBO J. 20 2001 6404 6413
-
(2001)
EMBO J.
, vol.20
, pp. 6404-6413
-
-
Wang, T.1
Kobayashi, T.2
Takimoto, R.3
Denes, A.E.4
Snyder, E.L.5
El-Deiry, W.S.6
Brachmann, R.K.7
-
66
-
-
0035844255
-
Ligand-dependent formation of retinoid receptors, receptor-interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140
-
L.N. Wei, M. Farooqui, and X. Hu Ligand-dependent formation of retinoid receptors, receptor-interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140 J. Biol. Chem. 276 2001 16107 16112
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16107-16112
-
-
Wei, L.N.1
Farooqui, M.2
Hu, X.3
-
67
-
-
0042405145
-
Physical and functional interactions between PML and MDM2
-
X. Wei, Z.K. Yu, A. Ramalingam, S.R. Grossman, J.H. Yu, D.B. Bloch, and C.G. Maki Physical and functional interactions between PML and MDM2 J. Biol. Chem. 278 2003 29288 29297
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29288-29297
-
-
Wei, X.1
Yu, Z.K.2
Ramalingam, A.3
Grossman, S.R.4
Yu, J.H.5
Bloch, D.B.6
Maki, C.G.7
-
68
-
-
0347628818
-
P21Waf1/Cip1 as a therapeutic target in breast and other cancers
-
R.H. Weiss p21Waf1/Cip1 as a therapeutic target in breast and other cancers Cancer Cell 4 2003 425 429
-
(2003)
Cancer Cell
, vol.4
, pp. 425-429
-
-
Weiss, R.H.1
-
69
-
-
0141733054
-
Nuclear association of the cytoplasmic tail of MUC1 and β-catenin
-
Y. Wen, T. Caffrey, M. Wheelock, K. Johnson, and M. Hollingsworth Nuclear association of the cytoplasmic tail of MUC1 and β-catenin J. Biol. Chem. 278 2003 38029 38039
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38029-38039
-
-
Wen, Y.1
Caffrey, T.2
Wheelock, M.3
Johnson, K.4
Hollingsworth, M.5
-
70
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
G.S. Wu, T.F. Burns, E.R. McDonald 3rd, W. Jiang, R. Meng, I.D. Krantz, G. Kao, D.D. Gan, J.Y. Zhou, and R. Muschel KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene Nat. Genet. 17 1997 141 143
-
(1997)
Nat. Genet.
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald III, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
Kao, G.7
Gan, D.D.8
Zhou, J.Y.9
Muschel, R.10
-
71
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion
-
M. Yamamoto, A. Bharti, Y. Li, and D. Kufe Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion J. Biol. Chem. 272 1997 12492 12494
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
Kufe, D.4
-
72
-
-
0042818006
-
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
-
L. Yin, and D. Kufe Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress J. Biol. Chem. 278 2003 35458 35464
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35458-35464
-
-
Yin, L.1
Kufe, D.2
-
73
-
-
7944230166
-
MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress
-
L. Yin, L. Huang, and D. Kufe MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress J. Biol. Chem. 279 2004 45721 45727
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45721-45727
-
-
Yin, L.1
Huang, L.2
Kufe, D.3
-
74
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
J. Yu, L. Zhang, P.M. Hwang, K.W. Kinzler, and B. Vogelstein PUMA induces the rapid apoptosis of colorectal cancer cells Mol. Cell 7 2001 673 682
-
(2001)
Mol. Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
75
-
-
0029959878
-
Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53
-
Z. Yuan, Y. Huang, M. Fan, C. Sawers, S. Kharbanda, and D. Kufe Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53 J. Biol. Chem. 271 1996 26457 26460
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26457-26460
-
-
Yuan, Z.1
Huang, Y.2
Fan, M.3
Sawers, C.4
Kharbanda, S.5
Kufe, D.6
-
76
-
-
0031020908
-
Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase
-
Z. Yuan, Y. Huang, T. Ishiko, S. Kharbanda, R. Weichselbaum, and D. Kufe Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase Proc. Natl. Acad. Sci. USA 94 1997 1437 1440
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1437-1440
-
-
Yuan, Z.1
Huang, Y.2
Ishiko, T.3
Kharbanda, S.4
Weichselbaum, R.5
Kufe, D.6
-
77
-
-
0042346348
-
Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter
-
C. Zhang, M.M. Kavurma, A. Lai, and L.M. Khachigian Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter J. Biol. Chem. 278 2003 27903 27909
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27903-27909
-
-
Zhang, C.1
Kavurma, M.M.2
Lai, A.3
Khachigian, L.M.4
|