Bromelain, from pineapple stems, proteolytically blocks activation of extracellular regulated kinase-2 in T cells

Journal of Immunology

Volumn 163, Issue 5, 1999, Pages 2568-2575

  Mynott, Tracey L ^a,b   Ladhams, Andrew ^a,b   Scarmato, Pierre ^a,b   Engwerda, Christian R ^c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Cortecs ^*  (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BROMELAIN; CALCIUM IONOPHORE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PLANT EXTRACT; PROTEIN P21; RAF PROTEIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CYTOKINE PRODUCTION; ENZYME INHIBITION; HELPER CELL; IMMUNOMODULATION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; BROMELAINS; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; FRUIT; HUMANS; HYBRIDOMAS; HYDROLYSIS; INTERLEUKIN-2; JURKAT CELLS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; ONCOGENE PROTEIN P21(RAS); PHOSPHORYLATION; PLANT STEMS; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; T-LYMPHOCYTES; TYROSINE;

EID: 0033197918     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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