Characterization of the acidic and basic limbs of a bell-shaped pH profile in the inhibitory activity of bromelain inhibitor VI

Biopolymers

Volumn 81, Issue 4, 2006, Pages 309-319

  Hatano, Ken Ichi ^a,b   Sawano, Yoriko ^b   Miyakawa, Takuya ^b   Tanokura, Masaru ^b  

^a GUNMA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Bowman Birk inhibitor; Brome lain inhibitor; Cysteine proteinase; Hydrogen bond; pH inhibition profile; Site directed mutagenesis

Indexed keywords

ACIDS; CARBOXYLATION; ELECTROSTATICS; HYDROGEN BONDS; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; PH;

BOWMAN-BIRK INHIBITOR; BROME LAIN INHIBITOR; CYSTEINE PROTEINASE; PH-INHIBITION PROFILE; SITE-DIRECTED MUTAGENESIS;

ENZYME INHIBITION;

BOWMAN BIRK INHIBITOR; BROMELAIN; BROMELAIN INHIBITOR VI; CYSTEINE PROTEINASE; ENZYME INHIBITOR; PAPAIN; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; ENZYME INHIBITION; ENZYME KINETICS; HYDROGEN BOND; IC 50; PH; PROTEIN DOMAIN; PROTEIN FAMILY; PROTON NUCLEAR MAGNETIC RESONANCE; SITE DIRECTED MUTAGENESIS;

ANANAS; BROMELAINS; HYDROGEN-ION CONCENTRATION; KINETICS; MUTATION; PAPAIN; PLANT PROTEINS; PLANT STEMS; RECOMBINANT PROTEINS;

ANANAS COMOSUS; BROMUS;

EID: 33645082924     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20419     Document Type: Article

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