Targeting TRP channels in airway disorders

Current Topics in Medicinal Chemistry

Volumn 13, Issue 3, 2013, Pages 310-321

  Abbott Banner, Katharine ^a   Poll, Christopher ^b   Verkuyl, J Martin ^c  

^a Verona Pharma Plc   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c Novartis Institutes of Biomedical Research   (United Kingdom)

Author keywords

Airway hyper responsiveness; Cough; Inflammation; Remodeling; Respiratory; TRP

Indexed keywords

1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL] UREA; 1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL]UREA; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CORTICOSTEROID; CXCL2 CHEMOKINE; CYCLOOXYGENASE 2 INHIBITOR; ENDOTHELIN RECEPTOR ANTAGONIST; EPOXYICOSATRIENOIC ACID; FORMYLMETHIONYLLEUCYLPHENYLALANINE; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 13; INTERLEUKIN 8; N (4 ISOPROPYLPHENYL) 2 (1, 2, 3, 6 TETRAHYDRO 1, 3 DIMETHYL 2, 6 DIOXO 7H PURIN 7 YL) ACETAMIDE; N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; PHOSPHODIESTERASE V INHIBITOR; PROSTACYCLIN DERIVATIVE; ROFLUMILAST; STAT3 PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1 ANTAGONIST; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2; VANILLOID RECEPTOR 4; VANILLOID RECEPTOR ANTAGONIST;

ALLERGIC RHINITIS; ARTERY MUSCLE; ASTHMA; BLOOD VESSEL PERMEABILITY; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CELL PROLIFERATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; COUGHING; CYSTIC FIBROSIS; DISEASE EXACERBATION; FIBROSING ALVEOLITIS; HUMAN; INFLAMMATION; LUNG LAVAGE; MUCOCILIARY CLEARANCE; MUCUS SECRETION; NONHUMAN; PATHOPHYSIOLOGY; PHASE 1 CLINICAL TRIAL (TOPIC); PREVALENCE; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; QUALITY OF LIFE; RESPIRATORY TRACT DISEASE; REVIEW;

ANIMALS; HUMANS; MOLECULAR TARGETED THERAPY; RESPIRATORY TRACT DISEASES; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84876739730     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026611313030008     Document Type: Review

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