Gα12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation

Journal of Biological Chemistry

Volumn 282, Issue 32, 2007, Pages 23117-23128

  Nishida, Motohiro ^a   Onohara, Naoya ^a   Sato, Yoji ^b   Suda, Reiko ^a   Ogushi, Mariko ^a   Tanabe, Shihori ^b   Inoue, Ryuji ^c   Mori, Yasuo ^d   Kurose, Hitoshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c FUKUOKA UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC FIBROBLASTS; INHIBITORY POLYPEPTIDES; MYOFIBROBLAST FORMATION; REACTIVE OXYGEN SPECIES;

CARDIOLOGY; CELL CULTURE; COLLAGEN; POLYPEPTIDES; SYNTHESIS (CHEMICAL);

FIBROBLASTS;

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ANGIOTENSIN II; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALCIUM ION; CYCLOSPORIN A; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN TRPC6; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR NFAT; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; UNCLASSIFIED DRUG; COLLAGEN; ENZYME INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; TRRP6 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG INHIBITION; HEART MUSCLE CELL; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CYTOLOGY; FIBROBLAST; HEART MUSCLE; METABOLISM; MUSCLE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; UPREGULATION;

RATTUS;

ANIMALS; COLLAGEN; ENDOTHELIN-1; ENZYME INHIBITORS; FIBROBLASTS; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MUSCLE CELLS; MYOCARDIUM; NFATC TRANSCRIPTION FACTORS; RATS; RATS, SPRAGUE-DAWLEY; TRPC CATION CHANNELS; UP-REGULATION;

EID: 34548148938     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611780200     Document Type: Article

References (48)

1. Cohn, J. N., Ferrari, R., and Sharpe, N. (2000) J. Am. Coll. Cardiol. 35, 569-582
2. Manabe, I., Shindo, T., and Nagai, R. (2002) Circ. Res. 91, 1103-1113
3. Brown, R. D., Ambler, S. K., Mitchell, M. D., and Long, C. S. (2005) Annu. Rev. Pharmacol. Toxicol. 45, 657-687
4. Braudino, T. A., Carver, W., Giles, W., and Borg, T. K. (2006) Am. J. Physiol. 291, H1015-H1026
5. Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., and Brown, R. A. (2002) Nat. Rev. Mol. Cell Biol. 3, 349-363
6. Swaney, J. S., Roth, D. M., Olson, E. R., Naugle, J. E., Meszaros, J. G., and Insel, P. A. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 437-442
7. Powell, D. W., Mifflin, R. C., Valentich, J. D., Crowe, S. E., Saada, J. I., and West, A. B. (1999) Am. J. Physiol. 277, C1-C9
8. Serini, G., and Gabbiani, G. (1999) Exp. Cell Res. 250, 273-283
9. Kawano, H., Do, Y. S., Kawano, Y., Starnes, V., Barr, M., Law, R. E., and Hsueh, W. A. (2000) Circulation 101, 1130-1137
10. Katwa, L. C. (2003) Am. J. Physiol. 285, H1132-H1139
11. Wilkins, B. J., and Molkentin, J. D. (2004) Biochem. Biophys. Res. Commun. 322, 1178-1191
12. Onohara, N., Nishida, M., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., and Kurose, H. (2006) EMBO J. 25, 5305-5316
13. Shimoyama, M., Hayashi, D., Takimoto, E., Zou, Y., Oka, T., Uozumi, H., Kudoh, S., Shibasaki, F., Yazaki, Y., Nagai, R., and Komuro, I. (1999) Circulation 100, 2449-2454
14. Øie, E., Bjørnerheim, R., Clausen, O. P. F., and Attramadal, H. (2000) Am. J. Physiol. 278, H2115-H2123
15. Kolar, F., Papousek, F., MacNaughton, C., Pelouch, V., Milerova, M., and Korecky, B. (1996) Mol. Cell Biochem. 163, 253-260
16. Yang, G., Meguro, T., Hong, C., Asai, K., Takagi, G., Karoor, V. L., Sadoshima, J., Vatner, D. E., Bishop, S. P., and Vatner, S. F. (2001) J. Mol. Cell Cardiol. 33, 1505-1514
17. Fujii, T., Onohara, N., Maruyama, Y., Tanabe, S., Kobayashi, H., Fukutomi, M., Nagamatsu, Y., Nishihara, N., Inoue, R., Sumimoto, H., Shibasaki, F., Nagao, T., Nishida, M., and Kurose, H. (2005) J. Biol. Chem. 280, 23041-23047
18. Nagamatsu, Y., Nishida, M., Onohara, N., Fukutomi, M., Maruyama, Y., Kobayashi, H., Sato, Y., and Kurose, H. (2006) J. Pharmacol. Sci. 101, 144-150
19. Clapham, D. E. (2003) Nature 426, 517-524
20. Seth, M., Sumbilla, C., Mullen, S. P., Lewis, D., Klein, M. G., Hussain, A., Soboloff, J., Gill, D. L., and Inesi, G. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 16683-16688
21. Bush, E. W., Hood, D. B., Papst, P. J., Chapo, J. A., Minobe, W., Bristow, M. R., Olson, E. N., and McKinsey, T. A. (2006) J. Biol. Chem. 281, 33487-33496
22. Nishida, M., Maruyama, Y., Tanaka, R., Kontani, K., Nagao, T., and Kurose, H. (2000) Nature 408, 492-495
23. Maruyama, Y., Nishida, M., Sugimoto, Y., Tanabe, S., Turner, J. H., Kozasa, T., Wada, T., Nagao, T., and Kurose, H. (2002) Circ. Res. 91, 961-969
24. Arai, K., Maruyama, Y., Nishida, M., Tanabe, S., Takagahara, S., Kozasa, T., Mori, Y., Nagao, T., and Kurose, H. (2003) Mol. Pharmacol. 63, 478-488
25. Nishida, M., Tanabe, S., Maruyama, Y., Mangmool, S., Urayama, K., Nagamatsu, Y., Takagahara, S., Turner, J. H., Kozasa, T., Kobayashi, H., Sato, Y., Kawanishi, T., Inoue, R., Nagao, T., and Kurose, H. (2005) J. Biol. Chem. 280, 18434-18441
26. Inoue, R., Jensen, L. J., Shi, J., Morita, H., Nishida, M., Honda, A., and Ito, Y. (2006) Circ. Res. 99, 119-131
27. Nishida, M., Sugimoto, K., Hara, Y., Mori, E., Morii, T., Kurosaki, T., and Mori, Y. (2003) EMBO J. 22, 4677-4688
28. Hofmann, T., Obukhov, A. G., Schaefer, M., Harteneck, C., Gudermann, T., and Schultz, G. (1999) Nature 397, 259-263
29. Hisatsune, C., Kuroda, Y., Nakamura, K., Inoue, T., Nakamura, T., Michikawa, T., Mizutani, A., and Mikoshiba, K. (2004) J. Biol. Chem. 279, 18887-18894
30. Shi, C.-S., Sinnarajah, S., Cho, H., Kozasa, T., and Kehrl, J. H. (2000) J. Biol. Chem. 274, 24470-24476
31. Kim, M., Nozu, F., Kusama, K., and Imawari, M. (2006) Biochem. Biophys. Res. Commun. 339, 271-276
32. Lopez, I., Mak, E. C., Ding, J., Hamm, H. E., and Lomasney, J. W. (2001) J. Biol. Chem. 276, 2758-2765
33. Gohla, A., Harhammer, R., and Schultz, G. (1998) J. Biol. Chem. 273, 4653-4659
34. Yu, Y., Sweeney, M., Zhang, S., Platoshyn, O., Landsberg, J., Rothman, A., and Yuan, J. X-J. (2003) Am. J. Physiol. 284, C316-C330
35. Kunichika, N., Landsberg, J. W., Yu, Y., Kunichika, H., Thistlethwaite, P. A., Rubin, L. J., and Yuan, J. X. (2004) Am. J. Respir. Crit. Care. Med. 170, 1101-1107
36. Dietrich, A., Mederos y Schnizler, M., Gollasch, M., Gross, V., Storch, U., Dubrovska, G., Obst, M., Yildirim, E., Salanova, B., Kalwa, H., Essin, K., Pinkenburg, O. C., Luft, F., Gudermann, T., and Birnbaumer, L. (2005) Mol. Cell Biol. 25, 6980-6989
37. Kuwahara, K., Wang, Y., McAnally, J., Richardson, J. A., Bassel-Duby, R., Hill, J. A., and Olson, E. N. (2006) J. Clin. Invest. 116, 3114-3126
38. Koga, T., Matus, Y., Asagiri, M., Kodama, T., de Crombrugghe, B., Nakashima, K., and Takayanagi, H. (2005) Nat. Med. 11, 880-885
39. Spassova, M. A., Hewavitharana, T., Xu, W., Soboloff, J., and Gill, D. L. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 16586-16591
40. Lewis, R. S. (2007) Nature 446, 284-287
41. Liou, J., Kim, M. L., Heo, W. D., Jones, J. T., Myers, J. W., Ferrell, J. E. Jr., and Meyer, T. (2005) Curr. Biol. 15, 1235-1241
42. Roos, J., DiGregorio, P. J., Yeromin, A. V., Ohlsen, K., Lioudyno, M., Zhang, S., Safrina, O., Kozak, J. A., Wagner, S. L., Cahalan, M. D., Velicelebi, G., and Stauderman, K. A. (2005) J. Cell Biol. 169, 435-445
43. Feske, S., Gwack, Y., Prakriya, M., Srikanth, S., Puppel, S. H., Tanasa, B., Hogan, P. G., Lewis, R. S., Daly, M., and Rao, A. (2006) Nature 441, 179-185
44. Vig, M., Peinelt, C., Beck, A., Koomoa, D. L., Rabah, D., Koblan-Huberson, M., Kraft, S., Turner, H., Fleig, A., Penner, R., and Kinet, J. P. (2006) Science 312, 1220-1223
45. Molkentin, J. D., Lu, J.-R., Antos, C. L., Markham, B., Richardson, J., Robbins, J., Grant, S. R., and Olson, E. N. (1998) Cell 93, 215-228
46. Nakayama, H., Wilkin, B. J., Bodi, I., and Molkentin, J. D. (2006) FASEB J. 20, 1660-1670
47. Wilkins, B. J., Dai, Y.-S., Bueno, O. F., Parsons, S. A., Xu, J., Plank, D. M., Jones, F., Kimball, T. R., Jeffery, D., and Molkentin, J. D. (2004) Circ. Res. 94, 110-118
48. Frey, N., McKinsey, T. A., and Olson, E. N. (2000) Nat. Med. 6, 1221-1227