TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles

Environmental Health Perspectives

Volumn 119, Issue 6, 2011, Pages 784-793

  Li, Jinju ^a   Kanju, Patrick ^a   Patterson, Michael ^a   Chew, Wei Leong ^a   Cho, Seung Hyun ^b   Gilmour, Ian ^b   Oliver, Tim ^a   Yasuda, Ryohei ^a,c   Ghio, Andrew ^b   Simon, Sidney A ^a   Liedtke, Wolfgang ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Air pollution; COPD; DEP; Human bronchial epithelia; MMP 1; PAR 2; PI3 kinase; PLC 3; TRPV4; TRPV4p19s

Indexed keywords

CALCIUM ION; INTERSTITIAL COLLAGENASE; PHOSPHOLIPASE C BETA3; PROTEINASE ACTIVATED RECEPTOR 2; VANILLOID RECEPTOR 4;

ADULT; AIR POLLUTION; ARTICLE; BRONCHUS MUCOSA; CALCIUM TRANSPORT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CILIATED EPITHELIUM; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; EPITHELIUM CELL; EXHAUST GAS; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION;

CALCIUM; CELL LINE; HUMANS; MATRIX METALLOPROTEINASE 1; PARTICULATE MATTER; PHOSPHOLIPASE C BETA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTOR, PAR-2; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TRPV CATION CHANNELS; VEHICLE EMISSIONS;

EID: 79958839921     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002807     Document Type: Article

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