메뉴 건너뛰기




Volumn 112, Issue 5, 2013, Pages 1819-1831

Current drug targets for helminthic diseases

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIARYLPROPEN 1 ONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE; ALBENDAZOLE; ANTHELMINTIC AGENT; APIGENIN; BENZIMIDAZOLE DERIVATIVE; BITHIONOL; CLOSANTEL; CURCUMIN; CYCLODEPSIPEPTIDE; DERQUANTEL; EMODEPSIDE; ENZYME INHIBITOR; ETACRYNIC ACID; GOSSYPOL; IMIDAZOTHIAZOLE; IVERMECTIN; K 11017; K 11777; LEVAMISOLE; MACROLIDE; MONEPANTEL; MOXIDECTIN; NAFUREDIN; PLUMBAGIN; PRAZIQUANTEL; THIADIAZOLE DERIVATIVE; TIRANDAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84876293615     PISSN: 09320113     EISSN: 14321955     Source Type: Journal    
DOI: 10.1007/s00436-013-3383-6     Document Type: Review
Times cited : (44)

References (119)
  • 1
    • 79960107786 scopus 로고    scopus 로고
    • HelmCoP: An online resource for helminth functional genomics and drug and vaccine targets prioritization
    • 10.1371/journal.pone.0021832 21760913 1:CAS:528:DC%2BC3MXps1Chu7g%3D 10.1371/journal.pone.0021832
    • Abubucker S, Martin J, Taylor CM, Mitreva M (2011) HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritization. PLoS One 6(7):e21832. doi: 10.1371/journal.pone.0021832
    • (2011) PLoS One , vol.6 , Issue.7 , pp. 21832
    • Abubucker, S.1    Martin, J.2    Taylor, C.M.3    Mitreva, M.4
  • 2
    • 48949118048 scopus 로고    scopus 로고
    • Of mice, cattle, and humans: The immunology and treatment of river blindness
    • 10.1371/journal.pntd.0000217 18446236 10.1371/journal.pntd.0000217 1:CAS:528:DC%2BD1cXmt1Witb0%3D
    • Allen JE et al (2008) Of mice, cattle, and humans: the immunology and treatment of river blindness. PLoS Negl Trop Dis 2(4):e217. doi: 10.1371/journal.pntd.0000217
    • (2008) PLoS Negl Trop Dis , vol.2 , Issue.4 , pp. 217
    • Allen, J.E.1
  • 3
    • 33847048131 scopus 로고    scopus 로고
    • Drug transfer into target helminth parasites
    • 10.1016/j.pt.2007.01.003 17236810 1:CAS:528:DC%2BD2sXit1Grtbo%3D 10.1016/j.pt.2007.01.003
    • Alvarez LI, Mottier ML, Lanusse CE (2007) Drug transfer into target helminth parasites. Trends Parasitol 23(3):97-104. doi: 10.1016/j.pt.2007.01.003
    • (2007) Trends Parasitol , vol.23 , Issue.3 , pp. 97-104
    • Alvarez, L.I.1    Mottier, M.L.2    Lanusse, C.E.3
  • 4
    • 79955662226 scopus 로고    scopus 로고
    • Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni
    • doi: 10.1186/1471-2164-12-215
    • Andrade LF, et al. (2011) Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni. BMC Genomics 12:215 doi: 10.1186/1471-2164-12-215
    • (2011) BMC Genomics , vol.12 , pp. 215
    • Andrade, L.F.1
  • 5
    • 70350351432 scopus 로고    scopus 로고
    • Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: Structural and kinetic aspects
    • doi: 10.1074/jbc.M109.020701
    • Angelucci F, et al. (2009) Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem 284(42):28977-85 doi: 10.1074/jbc.M109.020701
    • (2009) J Biol Chem , vol.284 , Issue.42 , pp. 28977-28985
    • Angelucci, F.1
  • 6
    • 84873351661 scopus 로고    scopus 로고
    • Helminths: Immunoregulation and inflammatory diseases - Which side are Trichinella spp. and Toxocara spp. on?
    • 23365718
    • Aranzamendi C, Sofronic-Milosavljevic L, Pinelli E (2013) Helminths: immunoregulation and inflammatory diseases - which side are Trichinella spp. and Toxocara spp. on? J Parasitol Res 2013:329438
    • (2013) J Parasitol Res , vol.2013 , pp. 329438
    • Aranzamendi, C.1    Sofronic-Milosavljevic, L.2    Pinelli, E.3
  • 7
    • 66149110763 scopus 로고    scopus 로고
    • Antifilarial activity of 1,3-diarylpropen-1-one: Effect on glutathione-S-transferase, a phase II detoxification enzyme
    • 1:CAS:528:DC%2BD1MXmt1Kjsrg%3D
    • Awasthi SK et al (2009) Antifilarial activity of 1,3-diarylpropen-1-one: effect on glutathione-S-transferase, a phase II detoxification enzyme. AmJTrop Med Hyg 80(5):764-768
    • (2009) AmJTrop Med Hyg , vol.80 , Issue.5 , pp. 764-768
    • Awasthi, S.K.1
  • 8
    • 79952986488 scopus 로고    scopus 로고
    • Anthelmintic resistance: Markers for resistance, or susceptibility?
    • 10.1017/S0031182010001198 20825689 1:CAS:528:DC%2BC3MXpvFSlug%3D%3D 10.1017/S0031182010001198
    • Beech RN, Skuce P, Bartley DJ, Martin RJ, Prichard RK, Gilleard JS (2011) Anthelmintic resistance: markers for resistance, or susceptibility? Parasitology 138(2):160-174. doi: 10.1017/S0031182010001198
    • (2011) Parasitology , vol.138 , Issue.2 , pp. 160-174
    • Beech, R.N.1    Skuce, P.2    Bartley, D.J.3    Martin, R.J.4    Prichard, R.K.5    Gilleard, J.S.6
  • 9
    • 79953135337 scopus 로고    scopus 로고
    • Linked thioredoxin-glutathione systems in platyhelminth parasites: Alternative pathways for glutathione reduction and deglutathionylation
    • 10.1074/jbc.M110.170761 21051543 1:CAS:528:DC%2BC3MXhvVeqt7k%3D 10.1074/jbc.M110.170761
    • Bonilla M, Denicola A, Marino SM, Gladyshev VN, Salinas G (2011) Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation. J Biol Chem 286(7):4959-4967. doi: 10.1074/jbc.M110.170761
    • (2011) J Biol Chem , vol.286 , Issue.7 , pp. 4959-4967
    • Bonilla, M.1    Denicola, A.2    Marino, S.M.3    Gladyshev, V.N.4    Salinas, G.5
  • 10
    • 79956194079 scopus 로고    scopus 로고
    • Structural and functional characterization of Schistosoma mansoni thioredoxin
    • 10.1002/pro.634 21465612 1:CAS:528:DC%2BC3MXmtFSnu78%3D 10.1002/pro.634
    • Boumis G, Angelucci F, Bellelli A, Brunori M, Dimastrogiovanni D, Miele AE (2011) Structural and functional characterization of Schistosoma mansoni thioredoxin. Protein Sci 20(6):1069-1076. doi: 10.1002/pro.634
    • (2011) Protein Sci , vol.20 , Issue.6 , pp. 1069-1076
    • Boumis, G.1    Angelucci, F.2    Bellelli, A.3    Brunori, M.4    Dimastrogiovanni, D.5    Miele, A.E.6
  • 11
    • 68249149173 scopus 로고    scopus 로고
    • An updated atlas of human helminth infections: The example of East Africa
    • 10.1186/1476-072X-8-42 19589144 10.1186/1476-072X-8-42
    • Brooker S et al (2009) An updated atlas of human helminth infections: the example of East Africa. Int J Health Geogr 8:42. doi: 10.1186/1476-072X-8-42
    • (2009) Int J Health Geogr , vol.8 , pp. 42
    • Brooker, S.1
  • 12
    • 84865025604 scopus 로고    scopus 로고
    • Anthelmintic metabolism in parasitic helminths: Proteomic insights
    • 10.1017/S003118201200087X 22776506 1:CAS:528:DC%2BC38Xht1WltLnF 10.1017/S003118201200087X
    • Brophy PM, MacKintosh N, Morphew RM (2012) Anthelmintic metabolism in parasitic helminths: proteomic insights. Parasitology 139(9):1205-1217. doi: 10.1017/S003118201200087X
    • (2012) Parasitology , vol.139 , Issue.9 , pp. 1205-1217
    • Brophy, P.M.1    Mackintosh, N.2    Morphew, R.M.3
  • 13
    • 33646096994 scopus 로고    scopus 로고
    • The SLO-1 BK channel of Caenorhabditis elegans is critical for muscle function and is involved in dystrophin-dependent muscle dystrophy
    • 10.1016/j.jmb.2006.02.037 16527307 1:CAS:528:DC%2BD28XjvVamt7k%3D 10.1016/j.jmb.2006.02.037
    • Carre-Pierrat M et al (2006) The SLO-1 BK channel of Caenorhabditis elegans is critical for muscle function and is involved in dystrophin-dependent muscle dystrophy. J Mol Biol 358(2):387-395. doi: 10.1016/j.jmb.2006.02.037
    • (2006) J Mol Biol , vol.358 , Issue.2 , pp. 387-395
    • Carre-Pierrat, M.1
  • 14
    • 79952111449 scopus 로고    scopus 로고
    • Liver fluke beta-tubulin isotype 2 binds albendazole and is thus a probable target of this drug
    • 10.1007/s00436-010-1997-5 20676683 10.1007/s00436-010-1997-5
    • Chambers E et al (2010) Liver fluke beta-tubulin isotype 2 binds albendazole and is thus a probable target of this drug. Parasitol Res 107(5):1257-1264. doi: 10.1007/s00436-010-1997-5
    • (2010) Parasitol Res , vol.107 , Issue.5 , pp. 1257-1264
    • Chambers, E.1
  • 15
    • 70350489312 scopus 로고    scopus 로고
    • The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling
    • 10.1021/bi9009677 19772353 1:CAS:528:DC%2BD1MXht1Cgtr%2FO 10.1021/bi9009677
    • Chen M et al (2009) The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. Biochemistry 48(43):10267-10274. doi: 10.1021/bi9009677
    • (2009) Biochemistry , vol.48 , Issue.43 , pp. 10267-10274
    • Chen, M.1
  • 16
    • 79960668852 scopus 로고    scopus 로고
    • Molecular characterization of cathepsin B from Clonorchis sinensis excretory/secretory products and assessment of its potential for serodiagnosis of clonorchiasis
    • 10.1186/1756-3305-4-149 21794140 1:CAS:528:DC%2BC3MXhtVOrtrbL 10.1186/1756-3305-4-149
    • Chen W et al (2011) Molecular characterization of cathepsin B from Clonorchis sinensis excretory/secretory products and assessment of its potential for serodiagnosis of clonorchiasis. Parasit Vectors 4:149. doi: 10.1186/1756-3305-4-149
    • (2011) Parasit Vectors , vol.4 , pp. 149
    • Chen, W.1
  • 17
    • 0023636575 scopus 로고
    • Heterologous antagonistic and synergistic interactions between helminths and between helminths and protozoans in concurrent experimental infection of mammalian hosts
    • 3309940 1:STN:280:DyaL1c%2Fhs1Whtw%3D%3D 10.1007/BF00538196
    • Christensen NO, Nansen P, Fagbemi BO, Monrad J (1987) Heterologous antagonistic and synergistic interactions between helminths and between helminths and protozoans in concurrent experimental infection of mammalian hosts. Parasitol Res 73(5):387-410
    • (1987) Parasitol Res , vol.73 , Issue.5 , pp. 387-410
    • Christensen, N.O.1    Nansen, P.2    Fagbemi, B.O.3    Monrad, J.4
  • 18
    • 77954601823 scopus 로고    scopus 로고
    • Our wormy world genomics, proteomics and transcriptomics in east and southeast Asia
    • 10.1016/S0065-308X(10)73011-6 20627147 10.1016/S0065-308X(10)73011-6
    • Chuan J et al (2010) Our wormy world genomics, proteomics and transcriptomics in east and southeast Asia. Adv Parasitol 73:327-371. doi: 10.1016/S0065-308X(10)73011-6
    • (2010) Adv Parasitol , vol.73 , pp. 327-371
    • Chuan, J.1
  • 19
    • 79956336717 scopus 로고    scopus 로고
    • Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans
    • 10.1124/mol.111.071043 21415309 1:CAS:528:DC%2BC3MXmvFGnurc%3D 10.1124/mol.111.071043
    • Crisford A et al (2011) Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans. Mol Pharmacol 79(6):1031-1043. doi: 10.1124/mol.111.071043
    • (2011) Mol Pharmacol , vol.79 , Issue.6 , pp. 1031-1043
    • Crisford, A.1
  • 20
    • 78149249050 scopus 로고    scopus 로고
    • Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
    • 10.1371/journal.pntd.0000804 20808766 10.1371/journal.pntd.0000804 1:CAS:528:DC%2BC3cXhtVynsr7J
    • Crowther GJ et al (2010) Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. PLoS Negl Trop Dis 4(8):e804. doi: 10.1371/journal.pntd.0000804
    • (2010) PLoS Negl Trop Dis , vol.4 , Issue.8 , pp. 804
    • Crowther, G.J.1
  • 21
    • 77952189065 scopus 로고    scopus 로고
    • Improvement in the antifilarial efficacy of doxycycline and rifampicin by combination therapy and drug delivery approach
    • 10.3109/10611860903450007 10.3109/10611860903450007 1:CAS:528: DC%2BC3cXls1Wqu7s%3D
    • Dangi A, Dwivedi V, Vedi S, Owais M, Misra-Bhattacharya S (2009) Improvement in the antifilarial efficacy of doxycycline and rifampicin by combination therapy and drug delivery approach. J Drug Target 18(5):343-350. doi: 10.3109/10611860903450007
    • (2009) J Drug Target , vol.18 , Issue.5 , pp. 343-350
    • Dangi, A.1    Dwivedi, V.2    Vedi, S.3    Owais, M.4    Misra-Bhattacharya, S.5
  • 23
    • 57049129327 scopus 로고    scopus 로고
    • Praziquantel: Mechanisms of action, resistance and new derivatives for schistosomiasis
    • 10.1097/QCO.0b013e328318978f 18978535 1:CAS:528:DC%2BD1cXhtlWltbzN 10.1097/QCO.0b013e328318978f
    • Doenhoff MJ, Cioli D, Utzinger J (2008) Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Curr Opin Infect Dis 21(6):659-667. doi: 10.1097/QCO.0b013e328318978f
    • (2008) Curr Opin Infect Dis , vol.21 , Issue.6 , pp. 659-667
    • Doenhoff, M.J.1    Cioli, D.2    Utzinger, J.3
  • 24
    • 84870821717 scopus 로고    scopus 로고
    • Design, synthesis, anti-schistosomal activity and molecular docking of novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives
    • 10.1016/j.bioorg.2012.10.003 23247256 10.1016/j.bioorg.2012.10.003 1:CAS:528:DC%2BC3sXhs1ent78%3D
    • Eweas AF, Allam G, Abuelsaad AS, Alghamdi AH, Maghrabi IA (2012) Design, synthesis, anti-schistosomal activity and molecular docking of novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives. Bioorg Chem 46:17-25. doi: 10.1016/j.bioorg.2012.10.003
    • (2012) Bioorg Chem , vol.46 , pp. 17-25
    • Eweas, A.F.1    Allam, G.2    Abuelsaad, A.S.3    Alghamdi, A.H.4    Maghrabi, I.A.5
  • 25
    • 67651089647 scopus 로고    scopus 로고
    • Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin
    • 10.1016/j.ejphar.2009.06.023 19549517 1:CAS:528:DC%2BD1MXptlant78%3D 10.1016/j.ejphar.2009.06.023
    • Fontana AC et al (2009) Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin. Eur J Pharmacol 616(1-3):48-57. doi: 10.1016/j.ejphar.2009.06.023
    • (2009) Eur J Pharmacol , vol.616 , Issue.1-3 , pp. 48-57
    • Fontana, A.C.1
  • 26
    • 21144432943 scopus 로고    scopus 로고
    • The Wolbachia genome of Brugia malayi: Endosymbiont evolution within a human pathogenic nematode
    • 10.1371/journal.pbio.0030121 15780005 10.1371/journal.pbio.0030121 1:CAS:528:DC%2BD2MXjtlWltLo%3D
    • Foster J et al (2005) The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode. PLoS Biol 3(4):e121. doi: 10.1371/journal.pbio.0030121
    • (2005) PLoS Biol , vol.3 , Issue.4 , pp. 121
    • Foster, J.1
  • 27
    • 62949234003 scopus 로고    scopus 로고
    • The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: A candidate target for anti-filarial therapies
    • 10.1007/s00436-008-1287-7 19043737 10.1007/s00436-008-1287-7
    • Foster JM, Raverdy S, Ganatra MB, Colussi PA, Taron CH, Carlow CK (2009) The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies. Parasitol Res 104(5):1047-1052. doi: 10.1007/s00436-008-1287-7
    • (2009) Parasitol Res , vol.104 , Issue.5 , pp. 1047-1052
    • Foster, J.M.1    Raverdy, S.2    Ganatra, M.B.3    Colussi, P.A.4    Taron, C.H.5    Carlow, C.K.6
  • 28
    • 0031446115 scopus 로고    scopus 로고
    • Effects of gastrointestinal nematode infection on the ruminant immune system
    • 9460205 1:CAS:528:DyaK1cXhsFCktA%3D%3D 10.1016/S0304-4017(97)00104-0 discussion 337-43
    • Gasbarre LC (1997) Effects of gastrointestinal nematode infection on the ruminant immune system. Vet Parasitol 72(3-4):327-337, discussion 337-43
    • (1997) Vet Parasitol , vol.72 , Issue.3-4 , pp. 327-337
    • Gasbarre, L.C.1
  • 29
    • 78650308723 scopus 로고    scopus 로고
    • Functional analysis of novel aquaporins from Fasciola gigantica
    • 10.1016/j.molbiopara.2010.10.010 21073907 10.1016/j.molbiopara.2010.10. 010 1:CAS:528:DC%2BC3cXhsF2is7nI
    • Geadkaew A, von Bulow J, Beitz E, Grams SV, Viyanant V, Grams R (2010) Functional analysis of novel aquaporins from Fasciola gigantica. Mol Biochem Parasitol 175(2):144-153. doi: 10.1016/j.molbiopara.2010.10.010
    • (2010) Mol Biochem Parasitol , vol.175 , Issue.2 , pp. 144-153
    • Geadkaew, A.1    Von Bulow, J.2    Beitz, E.3    Grams, S.V.4    Viyanant, V.5    Grams, R.6
  • 30
    • 53649093771 scopus 로고    scopus 로고
    • Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: Antiparasitic activities of p38 MAPK inhibitors
    • doi: 10.1016/j.bcp.2008.08.020
    • Gelmedin V, Caballero-Gamiz R, Brehm K (2008) Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: antiparasitic activities of p38 MAPK inhibitors. Biochem Pharmacol 76(9):1068-81. doi: 10.1016/j.bcp.2008.08.020
    • (2008) Biochem Pharmacol , vol.76 , Issue.9 , pp. 1068-1081
    • Gelmedin, V.1    Caballero-Gamiz, R.2    Brehm, K.3
  • 31
    • 35148867124 scopus 로고    scopus 로고
    • The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans
    • 10.1016/j.ijpara.2007.05.006 17583712 1:CAS:528:DC%2BD2sXhtFKitLjJ 10.1016/j.ijpara.2007.05.006
    • Guest M et al (2007) The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans. Int J Parasitol 37(14):1577-1588. doi: 10.1016/j.ijpara.2007.05.006
    • (2007) Int J Parasitol , vol.37 , Issue.14 , pp. 1577-1588
    • Guest, M.1
  • 32
    • 84857013611 scopus 로고    scopus 로고
    • Functional genomics approaches in parasitic helminths
    • 10.1111/j.1365-3024.2011.01306.x
    • Hagen J, Lee EF, Fairlie WD, Kalinna BH (2011) Functional genomics approaches in parasitic helminths. Parasite Immunol 34(2-3):163-182. doi: 10.1111/j.1365-3024.2011.01306.x
    • (2011) Parasite Immunol , vol.34 , Issue.2-3 , pp. 163-182
    • Hagen, J.1    Lee, E.F.2    Fairlie, W.D.3    Kalinna, B.H.4
  • 33
    • 1542653119 scopus 로고    scopus 로고
    • Microscopy and the helminth parasite
    • 10.1016/j.micron.2003.12.001 15006362 1:CAS:528:DC%2BD2cXhvV2isrs%3D 10.1016/j.micron.2003.12.001
    • Halton DW (2004) Microscopy and the helminth parasite. Micron 35(5):361-390. doi: 10.1016/j.micron.2003.12.001
    • (2004) Micron , vol.35 , Issue.5 , pp. 361-390
    • Halton, D.W.1
  • 34
    • 77953618794 scopus 로고    scopus 로고
    • Schistosomes of small mammals from the Lake Victoria Basin, Kenya: New species, familiar species, and implications for schistosomiasis control
    • 10.1017/S0031182010000041 20380765 1:CAS:528:DC%2BC3cXmslekt7g%3D 10.1017/S0031182010000041
    • Hanelt B et al (2010) Schistosomes of small mammals from the Lake Victoria Basin, Kenya: new species, familiar species, and implications for schistosomiasis control. Parasitology 137(7):1109-1118. doi: 10.1017/S0031182010000041
    • (2010) Parasitology , vol.137 , Issue.7 , pp. 1109-1118
    • Hanelt, B.1
  • 35
    • 79957953215 scopus 로고    scopus 로고
    • Principles of activation and permeation in an anion-selective Cys-loop receptor
    • 10.1038/nature10139 21572436 1:CAS:528:DC%2BC3MXmsFyqt7Y%3D 10.1038/nature10139
    • Hibbs RE, Gouaux E (2011) Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature 474(7349):54-60. doi: 10.1038/nature10139
    • (2011) Nature , vol.474 , Issue.7349 , pp. 54-60
    • Hibbs, R.E.1    Gouaux, E.2
  • 36
    • 84856978698 scopus 로고    scopus 로고
    • Producing parasitic helminth reference and draft genomes at the Wellcome Trust Sanger Institute
    • 10.1111/j.1365-3024.2011.01311.x 21707658 1:CAS:528:DC%2BC38Xlt1Wjsbs%3D 10.1111/j.1365-3024.2011.01311.x
    • Holroyd N, Sanchez-Flores A (2012) Producing parasitic helminth reference and draft genomes at the Wellcome Trust Sanger Institute. Parasite Immunol 34(2-3):100-107. doi: 10.1111/j.1365-3024.2011.01311.x
    • (2012) Parasite Immunol , vol.34 , Issue.2-3 , pp. 100-107
    • Holroyd, N.1    Sanchez-Flores, A.2
  • 37
    • 84873625686 scopus 로고    scopus 로고
    • Characterization and expression of the Schistosoma japonicum thioredoxin peroxidase-2 gene
    • 10.1645/GE-3096.1 22924918 10.1645/GE-3096.1 1:CAS:528: DC%2BC3sXjsVKju7c%3D
    • Hong Y et al (2012) Characterization and expression of the Schistosoma japonicum thioredoxin peroxidase-2 gene. J Parasitol 99(1):68-76. doi: 10.1645/GE-3096.1
    • (2012) J Parasitol , vol.99 , Issue.1 , pp. 68-76
    • Hong, Y.1
  • 38
    • 79961036674 scopus 로고    scopus 로고
    • Mapping the pro-peptide of the Schistosoma mansoni cathepsin B1 drug target: Modulation of inhibition by heparin and design of mimetic inhibitors
    • 10.1021/cb100411v 21375333 1:CAS:528:DC%2BC3MXjt1GitL0%3D 10.1021/cb100411v
    • Horn M, Jilkova A, Vondrasek J, Maresova L, Caffrey CR, Mares M (2011) Mapping the pro-peptide of the Schistosoma mansoni cathepsin B1 drug target: modulation of inhibition by heparin and design of mimetic inhibitors. ACS Chem Biol 6(6):609-617. doi: 10.1021/cb100411v
    • (2011) ACS Chem Biol , vol.6 , Issue.6 , pp. 609-617
    • Horn, M.1    Jilkova, A.2    Vondrasek, J.3    Maresova, L.4    Caffrey, C.R.5    Mares, M.6
  • 39
    • 41849114954 scopus 로고    scopus 로고
    • Helminth infections: The great neglected tropical diseases
    • 10.1172/JCI34261 18382743 1:CAS:528:DC%2BD1cXkt1Cntb4%3D 10.1172/JCI34261
    • Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J (2008) Helminth infections: the great neglected tropical diseases. J Clin Invest 118(4):1311-1321. doi: 10.1172/JCI34261
    • (2008) J Clin Invest , vol.118 , Issue.4 , pp. 1311-1321
    • Hotez, P.J.1    Brindley, P.J.2    Bethony, J.M.3    King, C.H.4    Pearce, E.J.5    Jacobson, J.6
  • 40
    • 34548422845 scopus 로고    scopus 로고
    • Control of neglected tropical diseases
    • 10.1056/NEJMra064142 17804846 1:CAS:528:DC%2BD2sXhtVegsb%2FM 10.1056/NEJMra064142
    • Hotez PJ et al (2007) Control of neglected tropical diseases. N Engl J Med 357(10):1018-1027. doi: 10.1056/NEJMra064142
    • (2007) N Engl J Med , vol.357 , Issue.10 , pp. 1018-1027
    • Hotez, P.J.1
  • 41
    • 33744486308 scopus 로고    scopus 로고
    • Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria
    • 10.1371/journal.pmed.0030102 16435908 10.1371/journal.pmed.0030102
    • Hotez PJ, Molyneux DH, Fenwick A, Ottesen E, Ehrlich Sachs S, Sachs JD (2006) Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med 3(5):e102. doi: 10.1371/journal.pmed.0030102
    • (2006) PLoS Med , vol.3 , Issue.5 , pp. 102
    • Hotez, P.J.1    Molyneux, D.H.2    Fenwick, A.3    Ottesen, E.4    Ehrlich Sachs, S.5    Sachs, J.D.6
  • 42
    • 77950544216 scopus 로고    scopus 로고
    • Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility
    • 10.1073/pnas.0912327107 20231450 1:CAS:528:DC%2BC3cXks1Kkt7o%3D 10.1073/pnas.0912327107
    • Hu Y, Platzer EG, Bellier A, Aroian RV (2010) Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility. Proc Natl Acad Sci U S A 107(13):5955-5960. doi: 10.1073/pnas.0912327107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.13 , pp. 5955-5960
    • Hu, Y.1    Platzer, E.G.2    Bellier, A.3    Aroian, R.V.4
  • 43
    • 70449511214 scopus 로고    scopus 로고
    • The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist
    • 10.1371/journal.pntd.0000499 19668355 10.1371/journal.pntd.0000499 1:CAS:528:DC%2BD1MXhtVWmt7vN
    • Hu Y, Xiao SH, Aroian RV (2009) The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist. PLoS Negl Trop Dis 3(8):e499. doi: 10.1371/journal.pntd.0000499
    • (2009) PLoS Negl Trop Dis , vol.3 , Issue.8 , pp. 499
    • Hu, Y.1    Xiao, S.H.2    Aroian, R.V.3
  • 44
    • 58649120308 scopus 로고    scopus 로고
    • Identification, expression, characterization, and immunolocalization of lactate dehydrogenase from Taenia asiatica
    • 10.1007/s00436-008-1190-2 18836746 10.1007/s00436-008-1190-2
    • Huang J, Huang Y, Wu X, Du W, Yu X, Hu X (2009) Identification, expression, characterization, and immunolocalization of lactate dehydrogenase from Taenia asiatica. Parasitol Res 104(2):287-293. doi: 10.1007/s00436-008- 1190-2
    • (2009) Parasitol Res , vol.104 , Issue.2 , pp. 287-293
    • Huang, J.1    Huang, Y.2    Wu, X.3    Du, W.4    Yu, X.5    Hu, X.6
  • 45
    • 84866059077 scopus 로고    scopus 로고
    • Identification and characterization of myophilin-like protein: A life stage and tissue-specific antigen of Clonorchis sinensis
    • 10.1007/s00436-012-2946-2 22752695 10.1007/s00436-012-2946-2
    • Huang Y et al (2012) Identification and characterization of myophilin-like protein: a life stage and tissue-specific antigen of Clonorchis sinensis. Parasitol Res 111(3):1143-1150. doi: 10.1007/s00436-012-2946-2
    • (2012) Parasitol Res , vol.111 , Issue.3 , pp. 1143-1150
    • Huang, Y.1
  • 46
    • 67649550594 scopus 로고    scopus 로고
    • Drug resistance mechanisms in helminths: Is it survival of the fittest?
    • 10.1016/j.pt.2009.04.004 19541539 1:CAS:528:DC%2BD1MXotF2gt7g%3D 10.1016/j.pt.2009.04.004
    • James CE, Hudson AL, Davey MW (2009) Drug resistance mechanisms in helminths: is it survival of the fittest? Trends Parasitol 25(7):328-335. doi: 10.1016/j.pt.2009.04.004
    • (2009) Trends Parasitol , vol.25 , Issue.7 , pp. 328-335
    • James, C.E.1    Hudson, A.L.2    Davey, M.W.3
  • 47
    • 80053911016 scopus 로고    scopus 로고
    • Structural basis for inhibition of cathepsin B drug target from the human blood fluke, Schistosoma mansoni
    • 10.1074/jbc.M111.271304 21832058 1:CAS:528:DC%2BC3MXht1yhtrnO 10.1074/jbc.M111.271304
    • Jilkova A et al (2011) Structural basis for inhibition of cathepsin B drug target from the human blood fluke, Schistosoma mansoni. J Biol Chem 286(41):35770-35781. doi: 10.1074/jbc.M111.271304
    • (2011) J Biol Chem , vol.286 , Issue.41 , pp. 35770-35781
    • Jilkova, A.1
  • 48
    • 77957768681 scopus 로고    scopus 로고
    • Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes
    • 10.1186/1756-3305-3-99 20946650 10.1186/1756-3305-3-99 1:CAS:528:DC%2BC3cXhtlelt7%2FF
    • Johnston KL, Wu B, Guimaraes A, Ford L, Slatko BE, Taylor MJ (2010) Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes. Parasit Vectors 3:99. doi: 10.1186/1756-3305-3-99
    • (2010) Parasit Vectors , vol.3 , pp. 99
    • Johnston, K.L.1    Wu, B.2    Guimaraes, A.3    Ford, L.4    Slatko, B.E.5    Taylor, M.J.6
  • 49
    • 17144426125 scopus 로고    scopus 로고
    • Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling
    • 10.1016/j.ijpara.2005.01.012 15826647 1:CAS:528:DC%2BD2MXjtF2gur8%3D 10.1016/j.ijpara.2005.01.012
    • Jones PM, George AM (2005) Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling. Int J Parasitol 35(5):555-566. doi: 10.1016/j.ijpara.2005.01.012
    • (2005) Int J Parasitol , vol.35 , Issue.5 , pp. 555-566
    • Jones, P.M.1    George, A.M.2
  • 50
    • 33745223646 scopus 로고    scopus 로고
    • Finding function in novel targets: C. elegans as a model organism
    • 10.1038/nrd2031 16672925 1:CAS:528:DC%2BD28XktVGmtr8%3D 10.1038/nrd2031
    • Kaletta T, Hengartner MO (2006) Finding function in novel targets: C. elegans as a model organism. Nat Rev Drug Discov 5(5):387-398. doi: 10.1038/nrd2031
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.5 , pp. 387-398
    • Kaletta, T.1    Hengartner, M.O.2
  • 51
    • 40749099893 scopus 로고    scopus 로고
    • A new class of anthelmintics effective against drug-resistant nematodes
    • 10.1038/nature06722 18337814 1:CAS:528:DC%2BD1cXjt1Gnu70%3D 10.1038/nature06722
    • Kaminsky R et al (2008) A new class of anthelmintics effective against drug-resistant nematodes. Nature 452(7184):176-180. doi: 10.1038/nature06722
    • (2008) Nature , vol.452 , Issue.7184 , pp. 176-180
    • Kaminsky, R.1
  • 52
    • 77955663602 scopus 로고    scopus 로고
    • Apigenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation
    • 10.1016/j.febslet.2010.07.026 20647014 1:CAS:528:DC%2BC3cXhtVehtrfP 10.1016/j.febslet.2010.07.026
    • Kawasaki I, Jeong MH, Oh BK, Shim YH (2010) Apigenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation. FEBS Lett 584(16):3587-3591. doi: 10.1016/j.febslet.2010.07.026
    • (2010) FEBS Lett , vol.584 , Issue.16 , pp. 3587-3591
    • Kawasaki, I.1    Jeong, M.H.2    Oh, B.K.3    Shim, Y.H.4
  • 53
    • 77954582391 scopus 로고    scopus 로고
    • The drugs we have and the drugs we need against major helminth infections
    • 10.1016/S0065-308X(10)73008-6 20627144 10.1016/S0065-308X(10)73008-6
    • Keiser J, Utzinger J (2010) The drugs we have and the drugs we need against major helminth infections. Adv Parasitol 73:197-230. doi: 10.1016/S0065-308X(10)73008-6
    • (2010) Adv Parasitol , vol.73 , pp. 197-230
    • Keiser, J.1    Utzinger, J.2
  • 54
    • 84864072856 scopus 로고    scopus 로고
    • Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production
    • 10.1038/bcj.2011.38 22829072 1:STN:280:DC%2BC38fislGlsg%3D%3D 10.1038/bcj.2011.38
    • Khanim FL et al (2011) Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production. Blood Cancer J 1(10):e39. doi: 10.1038/bcj.2011.38
    • (2011) Blood Cancer J , vol.1 , Issue.10 , pp. 39
    • Khanim, F.L.1
  • 55
    • 0242687126 scopus 로고    scopus 로고
    • Parasite mitochondria as drug target: Diversity and dynamic changes during the life cycle
    • 14529469 1:CAS:528:DC%2BD3sXpt1Kmsbg%3D 10.2174/0929867033456549
    • Kita K, Nihei C, Tomitsuka E (2003) Parasite mitochondria as drug target: diversity and dynamic changes during the life cycle. Curr Med Chem 10(23):2535-2548
    • (2003) Curr Med Chem , vol.10 , Issue.23 , pp. 2535-2548
    • Kita, K.1    Nihei, C.2    Tomitsuka, E.3
  • 56
    • 70349250327 scopus 로고    scopus 로고
    • Progress in the development of vaccines against helminths
    • 19670530
    • Kozak M, Kolodziej-Sobocinska M (2009) Progress in the development of vaccines against helminths. Wiad Parazytol 55(2):147-156
    • (2009) Wiad Parazytol , vol.55 , Issue.2 , pp. 147-156
    • Kozak, M.1    Kolodziej-Sobocinska, M.2
  • 57
    • 68249141238 scopus 로고    scopus 로고
    • The putative cyclooctadepsipeptide receptor depsiphilin of the canine hookworm Ancylostoma caninum
    • 10.1007/s00436-009-1500-3 19575230 10.1007/s00436-009-1500-3
    • Kruger N, Harder A, von Samson-Himmelstjerna G (2009) The putative cyclooctadepsipeptide receptor depsiphilin of the canine hookworm Ancylostoma caninum. Parasitol Res 105(Suppl 1):S91-S100. doi: 10.1007/s00436-009-1500-3
    • (2009) Parasitol Res , vol.105 , Issue.SUPPL. 1
    • Kruger, N.1    Harder, A.2    Von Samson-Himmelstjerna, G.3
  • 58
    • 57349179502 scopus 로고    scopus 로고
    • Synthesis of 4-amino-5-cyano-2, 6-disubstituted pyrimidines as a potential antifilarial DNA topoisomerase II inhibitors
    • 18991743 1:CAS:528:DC%2BD1cXhsVKgsb%2FL 10.2174/157340608786242115
    • Kumar A, Saxena JK, Chauhan PM (2008) Synthesis of 4-amino-5-cyano-2, 6-disubstituted pyrimidines as a potential antifilarial DNA topoisomerase II inhibitors. Med Chem 4(6):577-585
    • (2008) Med Chem , vol.4 , Issue.6 , pp. 577-585
    • Kumar, A.1    Saxena, J.K.2    Chauhan, P.M.3
  • 59
    • 43149083089 scopus 로고    scopus 로고
    • Mining predicted essential genes of Brugia malayi for nematode drug targets
    • 10.1371/journal.pone.0001189 18000556 10.1371/journal.pone.0001189 1:CAS:528:DC%2BD1cXjslSmsQ%3D%3D
    • Kumar S et al (2007) Mining predicted essential genes of Brugia malayi for nematode drug targets. PLoS One 2(11):e1189. doi: 10.1371/journal.pone. 0001189
    • (2007) PLoS One , vol.2 , Issue.11 , pp. 1189
    • Kumar, S.1
  • 60
    • 79960578633 scopus 로고    scopus 로고
    • Cloning, expression, purification and kinetics of trehalose-6-phosphate phosphatase of filarial parasite Brugia malayi
    • 10.1016/j.actatropica.2011.05.008 21658361 1:CAS:528:DC%2BC3MXptlWmtLY%3D 10.1016/j.actatropica.2011.05.008
    • Kushwaha S, Singh PK, Rana AK, Misra-Bhattacharya S (2011) Cloning, expression, purification and kinetics of trehalose-6-phosphate phosphatase of filarial parasite Brugia malayi. Acta Trop 119(2-3):151-159. doi: 10.1016/j.actatropica.2011.05.008
    • (2011) Acta Trop , vol.119 , Issue.2-3 , pp. 151-159
    • Kushwaha, S.1    Singh, P.K.2    Rana, A.K.3    Misra-Bhattacharya, S.4
  • 61
    • 84865972323 scopus 로고    scopus 로고
    • In vitro silencing of Brugia malayi trehalose-6-phosphate phosphatase impairs embryogenesis and in vivo development of infective larvae in jirds
    • 10.1371/journal.pntd.0001770 22905273 1:CAS:528:DC%2BC38Xht1ejtbvL 10.1371/journal.pntd.0001770
    • Kushwaha S, Singh PK, Shahab M, Pathak M, Bhattacharya SM (2012) In vitro silencing of Brugia malayi trehalose-6-phosphate phosphatase impairs embryogenesis and in vivo development of infective larvae in jirds. PLoS Negl Trop Dis 6(8):e1770. doi: 10.1371/journal.pntd.0001770
    • (2012) PLoS Negl Trop Dis , vol.6 , Issue.8 , pp. 1770
    • Kushwaha, S.1    Singh, P.K.2    Shahab, M.3    Pathak, M.4    Bhattacharya, S.M.5
  • 62
    • 79955561400 scopus 로고    scopus 로고
    • Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes
    • 10.1073/pnas.1100652108 21444803 1:CAS:528:DC%2BC3MXlslyqsLY%3D 10.1073/pnas.1100652108
    • Lee EF et al (2011) Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes. Proc Natl Acad Sci U S A 108(17):6999-7003. doi: 10.1073/pnas.1100652108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.17 , pp. 6999-7003
    • Lee, E.F.1
  • 64
    • 77957323451 scopus 로고    scopus 로고
    • Wnt4, the first member of the Wnt family identified in Schistosoma japonicum, regulates worm development by the canonical pathway
    • 10.1007/s00436-010-1933-8 20574838 10.1007/s00436-010-1933-8
    • Li HF et al (2010) Wnt4, the first member of the Wnt family identified in Schistosoma japonicum, regulates worm development by the canonical pathway. Parasitol Res 107(4):795-805. doi: 10.1007/s00436-010-1933-8
    • (2010) Parasitol Res , vol.107 , Issue.4 , pp. 795-805
    • Li, H.F.1
  • 65
    • 82555173782 scopus 로고    scopus 로고
    • Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy
    • 10.1371/journal.pntd.0001411 22140592 1:CAS:528:DC%2BC3MXhs1eqtb%2FM 10.1371/journal.pntd.0001411
    • Li Z, Garner AL, Gloeckner C, Janda KD, Carlow CK (2011) Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy. PLoS Negl Trop Dis 5(11):e1411. doi: 10.1371/journal.pntd.0001411
    • (2011) PLoS Negl Trop Dis , vol.5 , Issue.11 , pp. 1411
    • Li, Z.1    Garner, A.L.2    Gloeckner, C.3    Janda, K.D.4    Carlow, C.K.5
  • 66
    • 0038282311 scopus 로고    scopus 로고
    • The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery
    • 12769713 10.2174/1568026033452096
    • Lin J, Sahakian DC, de Morais SM, Xu JJ, Polzer RJ, Winter SM (2003) The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery. Curr Top Med Chem 3(10):1125-1154
    • (2003) Curr Top Med Chem , vol.3 , Issue.10 , pp. 1125-1154
    • Lin, J.1    Sahakian, D.C.2    De Morais, S.M.3    Xu, J.J.4    Polzer, R.J.5    Winter, S.M.6
  • 67
    • 84878367852 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Schistosoma japonicum aldose reductase
    • 10.1007/s00436-012-3166-5 23160889 10.1007/s00436-012-3166-5
    • Liu J et al (2012) Molecular cloning and characterization of Schistosoma japonicum aldose reductase. Parasitol Res 112(2):549-558. doi: 10.1007/s00436-012-3166-5
    • (2012) Parasitol Res , vol.112 , Issue.2 , pp. 549-558
    • Liu, J.1
  • 68
    • 77953911881 scopus 로고    scopus 로고
    • Schistosoma mansoni Polo-like kinase 1: A mitotic kinase with key functions in parasite reproduction
    • 10.1016/j.ijpara.2010.03.002 20350550 1:CAS:528:DC%2BC3cXnvVenu7Y%3D 10.1016/j.ijpara.2010.03.002
    • Long T et al (2010) Schistosoma mansoni Polo-like kinase 1: a mitotic kinase with key functions in parasite reproduction. Int J Parasitol 40(9):1075-1086. doi: 10.1016/j.ijpara.2010.03.002
    • (2010) Int J Parasitol , vol.40 , Issue.9 , pp. 1075-1086
    • Long, T.1
  • 69
    • 84863094463 scopus 로고    scopus 로고
    • SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: Conserved and unexpected roles in meiosis
    • 10.1371/journal.pone.0040045 22768216 1:CAS:528:DC%2BC38XpvVait7Y%3D 10.1371/journal.pone.0040045
    • Long T et al (2012) SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis. PLoS One 7(6):e40045. doi: 10.1371/journal.pone.0040045
    • (2012) PLoS One , vol.7 , Issue.6 , pp. 40045
    • Long, T.1
  • 70
    • 33748372564 scopus 로고    scopus 로고
    • Expression and characterization of lactate dehydrogenase from Schistosoma japonicum
    • 10.1007/s00436-006-0152-9 16688469 10.1007/s00436-006-0152-9
    • Lu G et al (2006) Expression and characterization of lactate dehydrogenase from Schistosoma japonicum. Parasitol Res 99(5):593-596. doi: 10.1007/s00436-006-0152-9
    • (2006) Parasitol Res , vol.99 , Issue.5 , pp. 593-596
    • Lu, G.1
  • 71
    • 79952277754 scopus 로고    scopus 로고
    • Neuropeptides in helminths: Occurrence and distribution
    • 21189674 1:CAS:528:DC%2BC3MXmtlOhuw%3D%3D 10.1007/978-1-4419-6902-6-4
    • Marks NJ, Maule AG (2010) Neuropeptides in helminths: occurrence and distribution. Adv Exp Med Biol 692:49-77
    • (2010) Adv Exp Med Biol , vol.692 , pp. 49-77
    • Marks, N.J.1    Maule, A.G.2
  • 72
    • 84862223905 scopus 로고    scopus 로고
    • Nematode.net update 2011: Addition of data sets and tools featuring next-generation sequencing data
    • (Database issue) doi: 10.1093/nar/gkr1194
    • Martin J, Abubucker S, Heizer E, Taylor CM, Mitreva M (2011) Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data. Nucleic Acids Res 40(Database issue):D720-8 doi: 10.1093/nar/gkr1194
    • (2011) Nucleic Acids Res , vol.40
    • Martin, J.1    Abubucker, S.2    Heizer, E.3    Taylor, C.M.4    Mitreva, M.5
  • 73
    • 77953650145 scopus 로고    scopus 로고
    • In vitro killing action of auranofin on Taenia crassiceps metacestode (cysticerci) and inactivation of thioredoxin-glutathione reductase (TGR)
    • 10.1007/s00436-010-1867-1 20431894 10.1007/s00436-010-1867-1
    • Martinez-Gonzalez JJ, Guevara-Flores A, Alvarez G, Rendon-Gomez JL, Del Arenal IP (2010) In vitro killing action of auranofin on Taenia crassiceps metacestode (cysticerci) and inactivation of thioredoxin-glutathione reductase (TGR). Parasitol Res 107(1):227-231. doi: 10.1007/s00436-010-1867-1
    • (2010) Parasitol Res , vol.107 , Issue.1 , pp. 227-231
    • Martinez-Gonzalez, J.J.1    Guevara-Flores, A.2    Alvarez, G.3    Rendon-Gomez, J.L.4    Del Arenal, I.P.5
  • 74
    • 84864664146 scopus 로고    scopus 로고
    • Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula
    • 10.1186/1756-3305-5-165 22876861 10.1186/1756-3305-5-165
    • Marxer M, Ingram K, Keiser J (2012) Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula. Parasit Vectors 5:165. doi: 10.1186/1756-3305-5-165
    • (2012) Parasit Vectors , vol.5 , pp. 165
    • Marxer, M.1    Ingram, K.2    Keiser, J.3
  • 75
    • 66849084012 scopus 로고    scopus 로고
    • An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus
    • 10.1124/mol.108.053363 19336526 1:CAS:528:DC%2BD1MXmvVWqsbw%3D 10.1124/mol.108.053363
    • McCavera S, Rogers AT, Yates DM, Woods DJ, Wolstenholme AJ (2009) An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus. Mol Pharmacol 75(6):1347-1355. doi: 10.1124/mol.108.053363
    • (2009) Mol Pharmacol , vol.75 , Issue.6 , pp. 1347-1355
    • McCavera, S.1    Rogers, A.T.2    Yates, D.M.3    Woods, D.J.4    Wolstenholme, A.J.5
  • 76
    • 67650588812 scopus 로고    scopus 로고
    • Discovery of multiple neuropeptide families in the phylum Platyhelminthes
    • 10.1016/j.ijpara.2009.03.005 19361512 1:CAS:528:DC%2BD1MXos12rsLk%3D 10.1016/j.ijpara.2009.03.005
    • McVeigh P et al (2009) Discovery of multiple neuropeptide families in the phylum Platyhelminthes. Int J Parasitol 39(11):1243-1252. doi: 10.1016/j.ijpara.2009.03.005
    • (2009) Int J Parasitol , vol.39 , Issue.11 , pp. 1243-1252
    • McVeigh, P.1
  • 77
    • 1242270525 scopus 로고    scopus 로고
    • 4-Methyl-7-(tetradecanoyl)-2H-1-benzopyran-2-one: A novel DNA topoisomerase II inhibitor with adulticidal and embryostatic activity against sub-periodic Brugia malayi
    • 10.1007/s00436-003-1014-3 14652743 10.1007/s00436-003-1014-3
    • Misra-Bhattacharya S, Katiyar D, Bajpai P, Tripathi RP, Saxena JK (2004) 4-Methyl-7-(tetradecanoyl)-2H-1-benzopyran-2-one: a novel DNA topoisomerase II inhibitor with adulticidal and embryostatic activity against sub-periodic Brugia malayi. Parasitol Res 92(3):177-182. doi: 10.1007/s00436-003-1014-3
    • (2004) Parasitol Res , vol.92 , Issue.3 , pp. 177-182
    • Misra-Bhattacharya, S.1    Katiyar, D.2    Bajpai, P.3    Tripathi, R.P.4    Saxena, J.K.5
  • 78
    • 82955227512 scopus 로고    scopus 로고
    • Gedunin and photogedunin of Xylocarpus granatum possess antifilarial activity against human lymphatic filarial parasite Brugia malayi in experimental rodent host
    • 10.1007/s00436-011-2380-x 21523424 10.1007/s00436-011-2380-x
    • Misra S, Verma M, Mishra SK, Srivastava S, Lakshmi V, Misra-Bhattacharya S (2011) Gedunin and photogedunin of Xylocarpus granatum possess antifilarial activity against human lymphatic filarial parasite Brugia malayi in experimental rodent host. Parasitol Res 109(5):1351-1360. doi: 10.1007/s00436-011-2380-x
    • (2011) Parasitol Res , vol.109 , Issue.5 , pp. 1351-1360
    • Misra, S.1    Verma, M.2    Mishra, S.K.3    Srivastava, S.4    Lakshmi, V.5    Misra-Bhattacharya, S.6
  • 79
    • 84859002085 scopus 로고    scopus 로고
    • Exploiting structural biology in the fight against parasitic diseases
    • doi: 10.1016/j.pt.2012.01.003
    • Modis Y (2012) Exploiting structural biology in the fight against parasitic diseases. Trends Parasitol. doi: 10.1016/j.pt.2012.01.003
    • (2012) Trends Parasitol
    • Modis, Y.1
  • 80
    • 79952278866 scopus 로고    scopus 로고
    • Neuropeptide physiology in helminths
    • 21189675 1:CAS:528:DC%2BC3MXmtlOgsg%3D%3D 10.1007/978-1-4419-6902-6-5
    • Mousley A, Novozhilova E, Kimber MJ, Day TA (2010) Neuropeptide physiology in helminths. Adv Exp Med Biol 692:78-97
    • (2010) Adv Exp Med Biol , vol.692 , pp. 78-97
    • Mousley, A.1    Novozhilova, E.2    Kimber, M.J.3    Day, T.A.4
  • 81
    • 59849122946 scopus 로고    scopus 로고
    • FMRFamide-like neuropeptides as putative ligands of the latrophilin-like HC110-R from Haemonchus contortus
    • 10.1016/j.molbiopara.2008.12.003 19126419 10.1016/j.molbiopara.2008.12. 003 1:CAS:528:DC%2BD1MXitVGitbw%3D
    • Muhlfeld S, Schmitt-Wrede HP, Harder A, Wunderlich F (2009) FMRFamide-like neuropeptides as putative ligands of the latrophilin-like HC110-R from Haemonchus contortus. Mol Biochem Parasitol 164(2):162-164. doi: 10.1016/j.molbiopara.2008.12.003
    • (2009) Mol Biochem Parasitol , vol.164 , Issue.2 , pp. 162-164
    • Muhlfeld, S.1    Schmitt-Wrede, H.P.2    Harder, A.3    Wunderlich, F.4
  • 82
    • 84864979856 scopus 로고    scopus 로고
    • Helminth parasite proteomics: From experimental models to human infections
    • 10.1017/S0031182011002423 22455721 1:CAS:528:DC%2BC38Xht1WltLbN 10.1017/S0031182011002423
    • Mutapi F (2012) Helminth parasite proteomics: from experimental models to human infections. Parasitology 139(9):1195-1204. doi: 10.1017/S0031182011002423
    • (2012) Parasitology , vol.139 , Issue.9 , pp. 1195-1204
    • Mutapi, F.1
  • 83
    • 68349085863 scopus 로고    scopus 로고
    • A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: Subversion of flatworm regenerative polarity
    • 10.1371/journal.pntd.0000464 19554083 10.1371/journal.pntd.0000464 1:CAS:528:DC%2BD1MXnsl2qu74%3D
    • Nogi T, Zhang D, Chan JD, Marchant JS (2009) A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: subversion of flatworm regenerative polarity. PLoS Negl Trop Dis 3(6):e464. doi: 10.1371/journal.pntd.0000464
    • (2009) PLoS Negl Trop Dis , vol.3 , Issue.6 , pp. 464
    • Nogi, T.1    Zhang, D.2    Chan, J.D.3    Marchant, J.S.4
  • 84
    • 0035793109 scopus 로고    scopus 로고
    • An anthelmintic compound, nafuredin, shows selective inhibition of complex i in helminth mitochondria
    • 10.1073/pnas.011524698 11120889 1:CAS:528:DC%2BD3MXkslKmug%3D%3D 10.1073/pnas.98.1.60
    • Omura S et al (2001) An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria. Proc Natl Acad Sci U S A 98(1):60-62. doi: 10.1073/pnas.011524698
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.1 , pp. 60-62
    • Omura, S.1
  • 85
    • 84861203412 scopus 로고    scopus 로고
    • A research agenda for helminth diseases of humans: Health research and capacity building in disease-endemic countries for helminthiases control
    • 10.1371/journal.pntd.0001602 22545167 10.1371/journal.pntd.0001602
    • Osei-Atweneboana MY, Lustigman S, Prichard RK, Boatin BA, Basanez MG (2012) A research agenda for helminth diseases of humans: health research and capacity building in disease-endemic countries for helminthiases control. PLoS Negl Trop Dis 6(4):e1602. doi: 10.1371/journal.pntd.0001602
    • (2012) PLoS Negl Trop Dis , vol.6 , Issue.4 , pp. 1602
    • Osei-Atweneboana, M.Y.1    Lustigman, S.2    Prichard, R.K.3    Boatin, B.A.4    Basanez, M.G.5
  • 86
    • 77950663440 scopus 로고    scopus 로고
    • Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths
    • 10.1186/1471-2164-11-237 20385027 10.1186/1471-2164-11-237 1:CAS:528:DC%2BC3cXltFWhtLc%3D
    • Otero L, Bonilla M, Protasio AV, Fernandez C, Gladyshev VN, Salinas G (2010) Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths. BMC Genomics 11:237. doi: 10.1186/1471-2164-11-237
    • (2010) BMC Genomics , vol.11 , pp. 237
    • Otero, L.1    Bonilla, M.2    Protasio, A.V.3    Fernandez, C.4    Gladyshev, V.N.5    Salinas, G.6
  • 87
    • 0141963900 scopus 로고    scopus 로고
    • Evolution of complex life cycles in helminth parasites
    • 10.1038/nature02012 14523438 1:CAS:528:DC%2BD3sXnslSisLc%3D 10.1038/nature02012
    • Parker GA, Chubb JC, Ball MA, Roberts GN (2003) Evolution of complex life cycles in helminth parasites. Nature 425(6957):480-484. doi: 10.1038/nature02012
    • (2003) Nature , vol.425 , Issue.6957 , pp. 480-484
    • Parker, G.A.1    Chubb, J.C.2    Ball, M.A.3    Roberts, G.N.4
  • 88
    • 77957317987 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a gene encoding methionine aminopeptidase 2 of Schistosoma japonicum
    • 10.1007/s00436-010-1956-1 20582436 10.1007/s00436-010-1956-1
    • Peng J, Han H, Hong Y, Fu Z, Liu J, Lin J (2010a) Molecular cloning and characterization of a gene encoding methionine aminopeptidase 2 of Schistosoma japonicum. Parasitol Res 107(4):939-946. doi: 10.1007/s00436-010-1956-1
    • (2010) Parasitol Res , vol.107 , Issue.4 , pp. 939-946
    • Peng, J.1    Han, H.2    Hong, Y.3    Fu, Z.4    Liu, J.5    Lin, J.6
  • 89
    • 77952540878 scopus 로고    scopus 로고
    • Molecular characterizations of an inhibitor of apoptosis from Schistosoma japonicum
    • 10.1007/s00436-010-1752-y 20162431 10.1007/s00436-010-1752-y
    • Peng J, Yang Y, Feng X, Cheng G, Lin J (2010b) Molecular characterizations of an inhibitor of apoptosis from Schistosoma japonicum. Parasitol Res 106(4):967-976. doi: 10.1007/s00436-010-1752-y
    • (2010) Parasitol Res , vol.106 , Issue.4 , pp. 967-976
    • Peng, J.1    Yang, Y.2    Feng, X.3    Cheng, G.4    Lin, J.5
  • 90
    • 77950021266 scopus 로고    scopus 로고
    • RNA interference in a cestode reveals specific silencing of selected highly expressed gene transcripts
    • 10.1016/j.ijpara.2009.10.012 19900457 10.1016/j.ijpara.2009.10.012 1:CAS:528:DC%2BC3cXjvFChtbs%3D
    • Pierson L, Mousley A, Devine L, Marks NJ, Day TA, Maule AG (2009) RNA interference in a cestode reveals specific silencing of selected highly expressed gene transcripts. Int J Parasitol 40(5):605-615. doi: 10.1016/j.ijpara.2009.10.012
    • (2009) Int J Parasitol , vol.40 , Issue.5 , pp. 605-615
    • Pierson, L.1    Mousley, A.2    Devine, L.3    Marks, N.J.4    Day, T.A.5    Maule, A.G.6
  • 91
    • 84859005658 scopus 로고    scopus 로고
    • A research agenda for helminth diseases of humans: Intervention for control and elimination
    • 10.1371/journal.pntd.0001549 22545163 10.1371/journal.pntd.0001549
    • Prichard RK et al (2012) A research agenda for helminth diseases of humans: intervention for control and elimination. PLoS Negl Trop Dis 6(4):e1549. doi: 10.1371/journal.pntd.0001549
    • (2012) PLoS Negl Trop Dis , vol.6 , Issue.4 , pp. 1549
    • Prichard, R.K.1
  • 92
    • 44349155277 scopus 로고    scopus 로고
    • An interactive map to assess the potential spread of Lymnaea truncatula and the free-living stages of Fasciola hepatica in Switzerland
    • 10.1016/j.vetpar.2008.03.030 18495343 10.1016/j.vetpar.2008.03.030
    • Rapsch C et al (2008) An interactive map to assess the potential spread of Lymnaea truncatula and the free-living stages of Fasciola hepatica in Switzerland. Vet Parasitol 154(3-4):242-249. doi: 10.1016/j.vetpar.2008.03.030
    • (2008) Vet Parasitol , vol.154 , Issue.3-4 , pp. 242-249
    • Rapsch, C.1
  • 93
    • 33748367860 scopus 로고    scopus 로고
    • Schistosomiasis - A century searching for chemotherapeutic drugs
    • 10.1007/s00436-006-0175-2 16636847 10.1007/s00436-006-0175-2
    • Ribeiro-dos-Santos G, Verjovski-Almeida S, Leite LC (2006) Schistosomiasis - a century searching for chemotherapeutic drugs. Parasitol Res 99(5):505-521. doi: 10.1007/s00436-006-0175-2
    • (2006) Parasitol Res , vol.99 , Issue.5 , pp. 505-521
    • Ribeiro-Dos-Santos, G.1    Verjovski-Almeida, S.2    Leite, L.C.3
  • 94
    • 36448980657 scopus 로고    scopus 로고
    • Ion-channels on parasite muscle: Pharmacology and physiology
    • 10.1007/s10158-007-0059-x 17999098 10.1007/s10158-007-0059-x
    • Robertson AP, Martin RJ (2007) Ion-channels on parasite muscle: pharmacology and physiology. Invert Neurosci 7(4):209-217. doi: 10.1007/s10158-007-0059-x
    • (2007) Invert Neurosci , vol.7 , Issue.4 , pp. 209-217
    • Robertson, A.P.1    Martin, R.J.2
  • 95
    • 66349115612 scopus 로고    scopus 로고
    • Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel
    • 10.1371/journal.ppat.1000380 19360096 10.1371/journal.ppat.1000380 1:CAS:528:DC%2BD1MXltFGnuro%3D
    • Rufener L, Maser P, Roditi I, Kaminsky R (2009) Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel. PLoS Pathog 5(4):e1000380. doi: 10.1371/journal.ppat.1000380
    • (2009) PLoS Pathog , vol.5 , Issue.4 , pp. 1000380
    • Rufener, L.1    Maser, P.2    Roditi, I.3    Kaminsky, R.4
  • 96
    • 84859424299 scopus 로고    scopus 로고
    • Mitochondrial fumarate reductase as a target of chemotherapy: From parasites to cancer cells
    • doi: 10.1016/j.bbagen.2011.12.013
    • Sakai C, Tomitsuka E, Esumi H, Harada S, Kita K (2011) Mitochondrial fumarate reductase as a target of chemotherapy: from parasites to cancer cells. Biochim Biophys Acta. doi: 10.1016/j.bbagen.2011.12.013
    • (2011) Biochim Biophys Acta
    • Sakai, C.1    Tomitsuka, E.2    Esumi, H.3    Harada, S.4    Kita, K.5
  • 97
    • 78149272883 scopus 로고    scopus 로고
    • The N terminus of a schistosome beta subunit regulates inactivation and current density of a Cav2 channel
    • 10.1074/jbc.M110.144725 20826800 1:CAS:528:DC%2BC3cXhtlyntLfF 10.1074/jbc.M110.144725
    • Salvador-Recatala V, Greenberg RM (2010) The N terminus of a schistosome beta subunit regulates inactivation and current density of a Cav2 channel. J Biol Chem 285(46):35878-35888. doi: 10.1074/jbc.M110.144725
    • (2010) J Biol Chem , vol.285 , Issue.46 , pp. 35878-35888
    • Salvador-Recatala, V.1    Greenberg, R.M.2
  • 98
    • 65549156021 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel immunoreactive ATPase/RNA helicase in human filarial parasite Brugia malayi
    • 10.1007/s00436-008-1251-6 19002498 10.1007/s00436-008-1251-6
    • Singh M, Srivastava KK, Bhattacharya SM (2009) Molecular cloning and characterization of a novel immunoreactive ATPase/RNA helicase in human filarial parasite Brugia malayi. Parasitol Res 104(4):753-761. doi: 10.1007/s00436-008- 1251-6
    • (2009) Parasitol Res , vol.104 , Issue.4 , pp. 753-761
    • Singh, M.1    Srivastava, K.K.2    Bhattacharya, S.M.3
  • 99
    • 84856462179 scopus 로고    scopus 로고
    • A novel filarial topoisomerase II inhibitor produced by native isolateMicrococcus luteus B1252
    • 1:CAS:528:DC%2BC3MXhsF2qurnE 10.5897/AJB11.907
    • Sivasamy R, Angayarkanni J, Palaniswamy M (2011) A novel filarial topoisomerase II inhibitor produced by native isolateMicrococcus luteus B1252. Afr J Biotechnol 10(71):16069-16077
    • (2011) Afr J Biotechnol , vol.10 , Issue.71 , pp. 16069-16077
    • Sivasamy, R.1    Angayarkanni, J.2    Palaniswamy, M.3
  • 100
    • 84863693534 scopus 로고    scopus 로고
    • Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni
    • 10.1371/journal.pntd.0001686 22720105 1:CAS:528:DC%2BC38XpsVygu7w%3D 10.1371/journal.pntd.0001686
    • Skinner DE et al (2012) Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni. PLoS Negl Trop Dis 6(6):e1686. doi: 10.1371/journal.pntd.0001686
    • (2012) PLoS Negl Trop Dis , vol.6 , Issue.6 , pp. 1686
    • Skinner, D.E.1
  • 101
    • 78651240094 scopus 로고    scopus 로고
    • Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi
    • 10.1371/journal.ppat.1001239 10.1371/journal.ppat.1001239 1:CAS:528:DC%2BC3MXjvVWjsA%3D%3D
    • Song C, Gallup JM, Day TA, Bartholomay LC, Kimber MJ (2011) Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi. PLoS Pathog 6(12):e1001239. doi: 10.1371/journal.ppat. 1001239
    • (2011) PLoS Pathog , vol.6 , Issue.12 , pp. 1001239
    • Song, C.1    Gallup, J.M.2    Day, T.A.3    Bartholomay, L.C.4    Kimber, M.J.5
  • 102
    • 59249083514 scopus 로고    scopus 로고
    • Axenic in vitro cultivation of Echinococcus multilocularis metacestode vesicles and the generation of primary cell cultures
    • doi: 10.1007/978-1-59745-204-5-17
    • Spiliotis M, Brehm K (2009) Axenic in vitro cultivation of Echinococcus multilocularis metacestode vesicles and the generation of primary cell cultures. Methods Mol Biol 470:245-62 doi: 10.1007/978-1-59745-204-5-17
    • (2009) Methods Mol Biol , vol.470 , pp. 245-262
    • Spiliotis, M.1    Brehm, K.2
  • 103
    • 69249217801 scopus 로고    scopus 로고
    • In vitro antifilarial activity of glutathione S-transferase inhibitors
    • 10.1007/s00436-009-1534-6 19562376 10.1007/s00436-009-1534-6
    • Srinivasan L, Mathew N, Muthuswamy K (2009) In vitro antifilarial activity of glutathione S-transferase inhibitors. Parasitol Res 105(4):1179-1182. doi: 10.1007/s00436-009-1534-6
    • (2009) Parasitol Res , vol.105 , Issue.4 , pp. 1179-1182
    • Srinivasan, L.1    Mathew, N.2    Muthuswamy, K.3
  • 104
    • 33748301926 scopus 로고    scopus 로고
    • Cloning and characterization of genes encoding alpha and beta subunits of glutamate-gated chloride channel protein in Cylicocyclus nassatus
    • 10.1016/j.molbiopara.2006.06.007 16872692 1:CAS:528:DC%2BD28XpsVWlsL0%3D 10.1016/j.molbiopara.2006.06.007
    • Tandon R, LePage KT, Kaplan RM (2006) Cloning and characterization of genes encoding alpha and beta subunits of glutamate-gated chloride channel protein in Cylicocyclus nassatus. Mol Biochem Parasitol 150(1):46-55. doi: 10.1016/j.molbiopara.2006.06.007
    • (2006) Mol Biochem Parasitol , vol.150 , Issue.1 , pp. 46-55
    • Tandon, R.1    Lepage, K.T.2    Kaplan, R.M.3
  • 105
    • 79955699715 scopus 로고    scopus 로고
    • Targeting protein-protein interactions for parasite control
    • 10.1371/journal.pone.0018381 21556146 1:CAS:528:DC%2BC3MXls1SmsLg%3D 10.1371/journal.pone.0018381
    • Taylor CM et al (2011) Targeting protein-protein interactions for parasite control. PLoS One 6(4):e18381. doi: 10.1371/journal.pone.0018381
    • (2011) PLoS One , vol.6 , Issue.4 , pp. 18381
    • Taylor, C.M.1
  • 106
    • 34447547675 scopus 로고    scopus 로고
    • The nematode neuropeptide, AF2 (KHEYLRF-NH2), increases voltage-activated calcium currents in Ascaris suum muscle
    • 10.1038/sj.bjp.0707296 17519945 1:CAS:528:DC%2BD2sXns1ylt7o%3D 10.1038/sj.bjp.0707296
    • Verma S, Robertson AP, Martin RJ (2007) The nematode neuropeptide, AF2 (KHEYLRF-NH2), increases voltage-activated calcium currents in Ascaris suum muscle. Br J Pharmacol 151(6):888-899. doi: 10.1038/sj.bjp.0707296
    • (2007) Br J Pharmacol , vol.151 , Issue.6 , pp. 888-899
    • Verma, S.1    Robertson, A.P.2    Martin, R.J.3
  • 107
    • 78651011618 scopus 로고
    • The physiology of helminth parasites in relation to disease
    • 4th Congr
    • Von Brand T (1948) The physiology of helminth parasites in relation to disease. Abstr Int Congr Trop Med Malar 56(4th Congr):77
    • (1948) Abstr Int Congr Trop Med Malar , vol.56 , pp. 77
    • Von Brand, T.1
  • 108
    • 58149252609 scopus 로고    scopus 로고
    • Helminth infections and intestinal inflammation
    • 18777588 1:CAS:528:DC%2BD1MXmtVCmtQ%3D%3D 10.3748/wjg.14.5125
    • Wang LJ, Cao Y, Shi HN (2008) Helminth infections and intestinal inflammation. World J Gastroenterol 14(33):5125-5132
    • (2008) World J Gastroenterol , vol.14 , Issue.33 , pp. 5125-5132
    • Wang, L.J.1    Cao, Y.2    Shi, H.N.3
  • 109
    • 67249153259 scopus 로고    scopus 로고
    • Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes
    • 10.1073/pnas.0904064106 19497877 1:CAS:528:DC%2BD1MXot1Sjs7g%3D 10.1073/pnas.0904064106
    • Wang Z et al (2009) Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes. Proc Natl Acad Sci U S A 106(23):9138-9143. doi: 10.1073/pnas.0904064106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.23 , pp. 9138-9143
    • Wang, Z.1
  • 110
    • 79955750096 scopus 로고    scopus 로고
    • SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants
    • 10.1371/journal.ppat.1001330 21490955 1:CAS:528:DC%2BC3MXltVWltbY%3D 10.1371/journal.ppat.1001330
    • Welz C et al (2011) SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants. PLoS Pathog 7(4):e1001330. doi: 10.1371/journal.ppat. 1001330
    • (2011) PLoS Pathog , vol.7 , Issue.4 , pp. 1001330
    • Welz, C.1
  • 111
    • 70049086953 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: Formation of two distinct drug targets by varying the relative expression levels of two subunits
    • 10.1371/journal.ppat.1000517 19609360 10.1371/journal.ppat.1000517 1:CAS:528:DC%2BD1MXptVKhtr0%3D
    • Williamson SM et al (2009) The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits. PLoS Pathog 5(7):e1000517. doi: 10.1371/journal.ppat.1000517
    • (2009) PLoS Pathog , vol.5 , Issue.7 , pp. 1000517
    • Williamson, S.M.1
  • 112
    • 36448930100 scopus 로고    scopus 로고
    • The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: A comparison with Caenorhabditis elegans
    • 10.1007/s10158-007-0056-0 17952476 1:CAS:528:DC%2BD2sXhtlCgsrzE 10.1007/s10158-007-0056-0
    • Williamson SM, Walsh TK, Wolstenholme AJ (2007) The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: a comparison with Caenorhabditis elegans. Invert Neurosci 7(4):219-226. doi: 10.1007/s10158-007-0056-0
    • (2007) Invert Neurosci , vol.7 , Issue.4 , pp. 219-226
    • Williamson, S.M.1    Walsh, T.K.2    Wolstenholme, A.J.3
  • 113
    • 84856824414 scopus 로고    scopus 로고
    • Ion channels and receptor as targets for the control of parasitic nematodes
    • 1:CAS:528:DC%2BC38XnslKksw%3D%3D 10.1016/j.ijpddr.2011.09.003
    • Wolstenholme AJ (2011) Ion channels and receptor as targets for the control of parasitic nematodes. Int J Parasitol Drugs Drug Resist 1:2-13
    • (2011) Int J Parasitol Drugs Drug Resist , vol.1 , pp. 2-13
    • Wolstenholme, A.J.1
  • 114
    • 70449482248 scopus 로고    scopus 로고
    • The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target
    • 10.1371/journal.pntd.0000475 19597542 10.1371/journal.pntd.0000475 1:CAS:528:DC%2BD1MXovVSktrw%3D
    • Wu B et al (2009) The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target. PLoS Negl Trop Dis 3(7):e475. doi: 10.1371/journal.pntd.0000475
    • (2009) PLoS Negl Trop Dis , vol.3 , Issue.7 , pp. 475
    • Wu, B.1
  • 115
    • 78449298414 scopus 로고    scopus 로고
    • RNAi-mediated silencing of a novel Ascaris suum gene expression in infective larvae
    • 10.1007/s00436-010-2027-3 20717832 1:STN:280:DC%2BC3cbls1ShtA%3D%3D 10.1007/s00436-010-2027-3
    • Xu MJ et al (2010) RNAi-mediated silencing of a novel Ascaris suum gene expression in infective larvae. Parasitol Res 107(6):1499-1503. doi: 10.1007/s00436-010-2027-3
    • (2010) Parasitol Res , vol.107 , Issue.6 , pp. 1499-1503
    • Xu, M.J.1
  • 116
    • 71849093559 scopus 로고    scopus 로고
    • Structural modeling and simulation studies of Brugia malayi glutathione-S-transferase with compounds exhibiting antifilarial activity: Implications in drug targeting and designing
    • 10.1016/j.jmgm.2009.10.003 19963420 1:CAS:528:DC%2BD1MXhsFymsLnN 10.1016/j.jmgm.2009.10.003
    • Yadav M, Singh A, Rathaur S, Liebau E (2010) Structural modeling and simulation studies of Brugia malayi glutathione-S-transferase with compounds exhibiting antifilarial activity: implications in drug targeting and designing. J Mol Graph Model 28(5):435-445. doi: 10.1016/j.jmgm.2009.10.003
    • (2010) J Mol Graph Model , vol.28 , Issue.5 , pp. 435-445
    • Yadav, M.1    Singh, A.2    Rathaur, S.3    Liebau, E.4
  • 117
    • 33645774162 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel lactate dehydrogenase gene from Clonorchis sinensis
    • 10.1007/s00436-005-0125-4 16479375 10.1007/s00436-005-0125-4
    • Yang G et al (2006) Molecular cloning and characterization of a novel lactate dehydrogenase gene from Clonorchis sinensis. Parasitol Res 99(1):55-64. doi: 10.1007/s00436-005-0125-4
    • (2006) Parasitol Res , vol.99 , Issue.1 , pp. 55-64
    • Yang, G.1
  • 118
    • 79955388062 scopus 로고    scopus 로고
    • Tirandamycins from Streptomyces sp. 17944 inhibiting the parasite Brugia malayi asparagine tRNA synthetase
    • 10.1021/ol200420u 21405052 1:CAS:528:DC%2BC3MXjtFekur0%3D 10.1021/ol200420u
    • Yu Z et al (2011) Tirandamycins from Streptomyces sp. 17944 inhibiting the parasite Brugia malayi asparagine tRNA synthetase. Org Lett 13(8):2034-2037. doi: 10.1021/ol200420u
    • (2011) Org Lett , vol.13 , Issue.8 , pp. 2034-2037
    • Yu, Z.1
  • 119
    • 61449522613 scopus 로고    scopus 로고
    • Research progress on the action of praziquantel on voltage-gated Ca2+ channel in schistosomes
    • 18637588 1:CAS:528:DC%2BD1cXns1Kitb4%3D
    • Zhang L, Zhou XN (2008) Research progress on the action of praziquantel on voltage-gated Ca2+ channel in schistosomes. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 26(1):58-62
    • (2008) Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi , vol.26 , Issue.1 , pp. 58-62
    • Zhang, L.1    Zhou, X.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.