SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants

PLoS Pathogens

Volumn 7, Issue 4, 2011, Pages

  Welz, Claudia ^a   Krüger, Nina ^b   Schniederjans, Monika ^a   Miltsch, Sandra M ^b   Krücken, Jürgen ^b   Guest, Marcus ^c   Holden Dye, Lindy ^c   Harder, Achim ^d   von Samson Himmelstjerna, Georg ^b  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; EMODEPSIDE; SLO 1 CHANNEL INHIBITOR; UNCLASSIFIED DRUG; ANTHELMINTIC AGENT; CAENORHABDITIS ELEGANS PROTEIN; DEPSIPEPTIDE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MYCOTOXIN; SLO 1 PROTEIN, C ELEGANS; SLO-1 PROTEIN, C ELEGANS; TREMORTIN;

ANCYLOSTOMA CANINUM; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; COOPERIA ONCOPHORA; DRUG SENSITIVITY; GENE; GENE EXPRESSION; GENE SEQUENCE; HAEMONCHUS CONTORTUS; INHIBITION KINETICS; JS379 GENE; LOCOMOTION; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; TRANSCRIPTION INITIATION; ANCYLOSTOMA; ANIMAL; DNA SEQUENCE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSFORMATION; GENETICS; HAEMONCHUS; METABOLISM; MOTOR ACTIVITY; MUTATION; PHENOTYPE; TRICHOSTRONGYLUS;

ANCYLOSTOMA CANINUM; CAENORHABDITIS ELEGANS; COOPERIA ONCOPHORA; HAEMONCHUS CONTORTUS; MAMMALIA; NEMATODA;

ANCYLOSTOMA; ANIMALS; ANTHELMINTICS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DEPSIPEPTIDES; GENE EXPRESSION REGULATION; HAEMONCHUS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MOTOR ACTIVITY; MUTATION; MYCOTOXINS; PHENOTYPE; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA; TRANSFORMATION, GENETIC; TRICHOSTRONGYLOIDEA;

EID: 79955750096     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001330     Document Type: Article

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