Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy

PLoS Neglected Tropical Diseases

Volumn 5, Issue 11, 2011, Pages

  Li, Zhiru ^a   Garner, Amanda L ^b   Gloeckner, Christian ^b   Janda, Kim D ^b   Carlow, Clotilde K ^a  

^a NEW ENGLAND BIOLABS   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; FTSZ PROTEIN; GUANOSINE TRIPHOSPHATASE; ANTIFILARIAL AGENT; ANTIINFECTIVE AGENT; BACTERIAL DNA; BACTERIAL PROTEIN; CYTOSKELETON PROTEIN; ENZYME INHIBITOR; FTSZ PROTEIN, BACTERIA;

ANTHELMINTIC ACTIVITY; ARTICLE; BACTERIAL GENE; BRUGIA MALAYI; CATALYSIS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DRUG TARGETING; ENDOSYMBIONT; ENZYME ACTIVITY; FTSZ GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; HIGH THROUGHPUT SCREENING; IMMOBILIZATION; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN TARGETING; STRUCTURE ACTIVITY RELATION; UPREGULATION; WOLBACHIA; ANIMAL; CHEMISTRY; DNA SEQUENCE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BERBERINE; BRUGIA MALAYI; CYTOSKELETAL PROTEINS; DNA, BACTERIAL; ENZYME INHIBITORS; FILARICIDES; GTP PHOSPHOHYDROLASES; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; WOLBACHIA;

EID: 82555173782     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001411     Document Type: Article

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