Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: Antiparasitic activities of p38 MAPK inhibitors

Biochemical Pharmacology

Volumn 76, Issue 9, 2008, Pages 1068-1081

  Gelmedin, Verena ^a   Caballero Gamiz, Rocio ^a   Brehm, Klaus ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cestode; Echinococcosis; Echinococcus; p38 MAP kinase; Parasite; Pyridinyl imidazole

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOSINE TRIPHOSPHATE; ANTIPARASITIC AGENT; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; ML 3403; PROTEIN EMMPK2; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; DRUG MECHANISM; ECHINOCOCCUS MULTILOCULARIS; EMMPK2 GENE; ENZYME ANALYSIS; ENZYME INHIBITION; ESCHERICHIA COLI; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG HYDATID CYST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FAMILY; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIPARASITIC AGENTS; CELL LINE; CELL LINE, TUMOR; ECHINOCOCCOSIS, PULMONARY; ECHINOCOCCUS MULTILOCULARIS; HUMANS; IMIDAZOLES; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PYRIDINES; RATS;

EID: 53649093771     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.08.020     Document Type: Article

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