In Vitro Silencing of Brugia malayi Trehalose-6-Phosphate Phosphatase Impairs Embryogenesis and In Vivo Development of Infective Larvae in Jirds

PLoS Neglected Tropical Diseases

Volumn 6, Issue 8, 2012, Pages

  Kushwaha, Susheela ^a   Singh, Prashant Kumar ^a   Shahab, Mohd ^a   Pathak, Manisha ^a   Bhattacharya, Shailja Misra ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PHOSPHATASE; SMALL INTERFERING RNA; TREHALOSE 6 PHOSPHATE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY MOVEMENT; BRUGIA MALAYI; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; GENE EXPRESSION; GENE SILENCING; HOST PARASITE INTERACTION; JIRD; LETHALITY; MALE; MICROFILARIA (NEMATODE LARVA); NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE ISOLATION; PARASITE VIABILITY; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; RODENT;

ANIMALS; BRUGIA MALAYI; DISEASE MODELS, ANIMAL; FEMALE; FILARIASIS; GENE SILENCING; GERBILLINAE; LARVA; PHOSPHORIC MONOESTER HYDROLASES; RNA, SMALL INTERFERING;

EID: 84865972323     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001770     Document Type: Article

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