An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 1, 2001, Pages 60-62

  Omura, Satoshi ^a   Miyadera, Hiroko ^b   Ui, Hideaki ^a   Shiomi, Kazuro ^a   Yamaguchi, Yuuichi ^a   Masuma, Rokuro ^a   Nagamitsu, Tohru ^a   Takano, Daisuke ^c   Sunazuka, Toshiaki ^c   Harder, Achim ^d   Kölbl, Heinz ^d   Namikoshi, Michio ^e   Miyoshi, Hideto ^f   Sakamoto, Kimitoshi ^f   Kita, Kiyoshi ^b  

^a KITASATO INSTITUTE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d BAYER AG   (Germany)

^e TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; FUMARATE REDUCTASE; NAFUREDIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLUS NIGER; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON TRANSPORT; ENZYME INHIBITION; HAEMONCHUS CONTORTUS; HELMINTHIASIS; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; SHEEP;

ANIMALIA; ASPERGILLUS NIGER; HAEMONCHUS CONTORTUS; NEMATODA; OVIS ARIES; VERMES;

EID: 0035793109     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.98.1.60     Document Type: Article

References (26)