-
1
-
-
6044246292
-
Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: A pressing public health agenda for helminth control
-
M. Albonico, D. Engels, and L. Savioli Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control Int. J. Parasitol. 34 2004 1205 1210
-
(2004)
Int. J. Parasitol.
, vol.34
, pp. 1205-1210
-
-
Albonico, M.1
Engels, D.2
Savioli, L.3
-
2
-
-
0033519070
-
The fall and rise of sleeping sickness
-
M.P. Barrett The fall and rise of sleeping sickness Lancet 353 1999 1113 1114
-
(1999)
Lancet
, vol.353
, pp. 1113-1114
-
-
Barrett, M.P.1
-
3
-
-
0036894232
-
Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion
-
M. Basselin, H. Denise, G.H. Coombs, and M.P. Barrett Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion Antimicrob. Agents Chemother. 46 2002 3731 3738
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 3731-3738
-
-
Basselin, M.1
Denise, H.2
Coombs, G.H.3
Barrett, M.P.4
-
4
-
-
0003989708
-
-
World Health Organization. WHO/CDS/CSR/DRS/2001.4.
-
Bloland, P.B., 2001. Drug Resistance in Malaria. World Health Organization. WHO/CDS/CSR/DRS/2001.4.
-
(2001)
Drug Resistance in Malaria
-
-
Bloland, P.B.1
-
5
-
-
0028244986
-
Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins
-
I.B. Bosch, Z.X. Wang, L.F. Tao, and C.B. Shoemaker Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins Mol. Biochem. Parasitol. 65 1994 351 356
-
(1994)
Mol. Biochem. Parasitol.
, vol.65
, pp. 351-356
-
-
Bosch, I.B.1
Wang, Z.X.2
Tao, L.F.3
Shoemaker, C.B.4
-
6
-
-
0031964307
-
A comparison of the phenomenology and genetics of multidrug resistance in cancer cells and quinolone resistance in Plasmodium falciparum
-
P.G. Bray, and S.A. Ward A comparison of the phenomenology and genetics of multidrug resistance in cancer cells and quinolone resistance in Plasmodium falciparum Pharmacol. Ther. 77 1998 1 28
-
(1998)
Pharmacol. Ther.
, vol.77
, pp. 1-28
-
-
Bray, P.G.1
Ward, S.A.2
-
8
-
-
0025945313
-
Heavy metal resistance: A new role for P-glycoproteins in Leishmania
-
H.L. Callahan, and S.M. Beverley Heavy metal resistance: a new role for P-glycoproteins in Leishmania J. Biol. Chem. 266 1991 18427 18430
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18427-18430
-
-
Callahan, H.L.1
Beverley, S.M.2
-
9
-
-
0027500261
-
Arsenical-resistant trypanosomes lack an unusual adenosine transporter
-
N.S. Carter, and A.H. Fairlamb Arsenical-resistant trypanosomes lack an unusual adenosine transporter Nature 361 1993 173 176
-
(1993)
Nature
, vol.361
, pp. 173-176
-
-
Carter, N.S.1
Fairlamb, A.H.2
-
10
-
-
0028875686
-
Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei
-
N.S. Carter, B.J. Berger, and A.H. Fairlamb Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei J. Biol. Chem. 270 1995 28153 28157
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28153-28157
-
-
Carter, N.S.1
Berger, B.J.2
Fairlamb, A.H.3
-
11
-
-
0038799725
-
Structure of MsbA from Vibrio cholera: A multidrug resistance ABC transporter homolog in a closed conformation
-
G. Chang Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation J. Mol. Biol. 330 2003 419 430
-
(2003)
J. Mol. Biol.
, vol.330
, pp. 419-430
-
-
Chang, G.1
-
12
-
-
0035823075
-
Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters
-
G. Chang, and C.B. Roth Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters Science 293 2001 1793 1800
-
(2001)
Science
, vol.293
, pp. 1793-1800
-
-
Chang, G.1
Roth, C.B.2
-
13
-
-
0344333486
-
Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line
-
M.J. Chiquero, J.M. Perez-Victoria, F. O'Valle, J.M. Gonzalez-Ros, R.G. del Moral, J.A. Ferragut, S. Castanys, and F. Gamarro Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line Biochem. Pharmacol. 55 1998 131 139
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 131-139
-
-
Chiquero, M.J.1
Perez-Victoria, J.M.2
O'Valle, F.3
Gonzalez-Ros, J.M.4
Del Moral, R.G.5
Ferragut, J.A.6
Castanys, S.7
Gamarro, F.8
-
14
-
-
0031751905
-
Plasmodium and Leishmania: The role of mdr genes in mediating drug resistance
-
L.M.C. Chow, and S.K. Volkman Plasmodium and Leishmania: the role of mdr genes in mediating drug resistance Exp. Parasitol. 90 1998 135 141
-
(1998)
Exp. Parasitol.
, vol.90
, pp. 135-141
-
-
Chow, L.M.C.1
Volkman, S.K.2
-
15
-
-
0027178549
-
Cloning and functional analysis of an extrachromosomally amplified multidrug resistance-like gene in Leishmania enriettii
-
L.M. Chow, A.K. Wong, B. Ullman, and D.F. Wirth Cloning and functional analysis of an extrachromosomally amplified multidrug resistance-like gene in Leishmania enriettii Mol. Biochem. Parasitol. 60 1993 195 208
-
(1993)
Mol. Biochem. Parasitol.
, vol.60
, pp. 195-208
-
-
Chow, L.M.1
Wong, A.K.2
Ullman, B.3
Wirth, D.F.4
-
16
-
-
0142106997
-
Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major
-
A.C. Coelho, S.M. Beverley, and P.C. Cotrim Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major Mol. Biochem. Parasitol. 130 2003 83 90
-
(2003)
Mol. Biochem. Parasitol.
, vol.130
, pp. 83-90
-
-
Coelho, A.C.1
Beverley, S.M.2
Cotrim, P.C.3
-
17
-
-
0025786518
-
A P-glycoprotein homologue of Plasmodium falciparum is located on the digestive vacuole
-
A.F. Cowman, S. Karcz, D. Galatis, and J.G. Culvenor A P-glycoprotein homologue of Plasmodium falciparum is located on the digestive vacuole J. Cell Biol. 113 1991 1033 1042
-
(1991)
J. Cell Biol.
, vol.113
, pp. 1033-1042
-
-
Cowman, A.F.1
Karcz, S.2
Galatis, D.3
Culvenor, J.G.4
-
18
-
-
0028036881
-
Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans
-
D.F. Cully, D.K. Vassilatis, K.K. Liu, P.S. Paress, L.H.T. Van der Ploeg, J.M. Schaeffer, and J.P. Arena Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans Nature 371 1994 707 711
-
(1994)
Nature
, vol.371
, pp. 707-711
-
-
Cully, D.F.1
Vassilatis, D.K.2
Liu, K.K.3
Paress, P.S.4
Van Der Ploeg, L.H.T.5
Schaeffer, J.M.6
Arena, J.P.7
-
19
-
-
0029942616
-
Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi
-
B. Dallagiovanna, F. Gamarro, and S. Castanys Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi Mol. Biochem. Parasitol. 75 1996 145 157
-
(1996)
Mol. Biochem. Parasitol.
, vol.75
, pp. 145-157
-
-
Dallagiovanna, B.1
Gamarro, F.2
Castanys, S.3
-
20
-
-
0035014565
-
The ABC of ABCs: A phylogenetic and functional classification of ABC systems in living organisms
-
E. Dassa, and P. Bouige The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms Res. Microbiol. 152 2001 211 229
-
(2001)
Res. Microbiol.
, vol.152
, pp. 211-229
-
-
Dassa, E.1
Bouige, P.2
-
21
-
-
1642443137
-
Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites
-
M.A. Dodge, R.F. Waller, L.M.C. Chow, M.M. Zaman, L.M. Cotton, M.J. McConville, and D.F. Wirth Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites Mol. Microbiol. 51 2004 1563 1575
-
(2004)
Mol. Microbiol.
, vol.51
, pp. 1563-1575
-
-
Dodge, M.A.1
Waller, R.F.2
Chow, L.M.C.3
Zaman, M.M.4
Cotton, L.M.5
McConville, M.J.6
Wirth, D.F.7
-
22
-
-
2942622405
-
Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and their relationship to chloroquine resistance in vitro
-
V. Durrand, A. Berry, R. Sem, P. Glaziou, J. Beaudou, and T. Fandeur Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and their relationship to chloroquine resistance in vitro Mol. Biochem. Parasitol. 136 2004 273 285
-
(2004)
Mol. Biochem. Parasitol.
, vol.136
, pp. 273-285
-
-
Durrand, V.1
Berry, A.2
Sem, R.3
Glaziou, P.4
Beaudou, J.5
Fandeur, T.6
-
23
-
-
0033827908
-
Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine
-
S.M. Dzekunov, L.M. Ursos, and P.D. Roepe Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine Mol. Biochem. Parasitol. 110 2000 107 124
-
(2000)
Mol. Biochem. Parasitol.
, vol.110
, pp. 107-124
-
-
Dzekunov, S.M.1
Ursos, L.M.2
Roepe, P.D.3
-
24
-
-
0036176213
-
Identification of ligand-binding regions of P-glycoprotein by activated-pharmacophore photoaffinity labeling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry
-
G.F. Ecker, E. Csaszar, S. Kopp, B. Plagens, W. Holzer, W. Ernst, and P. Chiba Identification of ligand-binding regions of P-glycoprotein by activated-pharmacophore photoaffinity labeling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry Mol. Pharmacol. 61 2002 637 648
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 637-648
-
-
Ecker, G.F.1
Csaszar, E.2
Kopp, S.3
Plagens, B.4
Holzer, W.5
Ernst, W.6
Chiba, P.7
-
25
-
-
0344611201
-
Chemotherapeutische Trypanosomen-Studien
-
P. Ehrlich Chemotherapeutische Trypanosomen-Studien Berliner klinische Wochenschrift 11 1907 310 314
-
(1907)
Berliner Klinische Wochenschrift
, vol.11
, pp. 310-314
-
-
Ehrlich, P.1
-
26
-
-
0030997216
-
In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: A study of 37 strains collected from patients with visceral leishmaniasis
-
F. Faraut-Gambarelli, R. Piarroux, M. Deniau, B. Giusiano, P. Marty, G. Michel, B. Faugere, and H. Dumon In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: a study of 37 strains collected from patients with visceral leishmaniasis Antimicrob. Agents Chemother. 41 1997 827 830
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 827-830
-
-
Faraut-Gambarelli, F.1
Piarroux, R.2
Deniau, M.3
Giusiano, B.4
Marty, P.5
Michel, G.6
Faugere, B.7
Dumon, H.8
-
27
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
-
S.J. Foote, J.K. Thompson, A.F. Cowman, and D.J. Kemp Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum Cell 57 1989 921 930
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
Thompson, J.K.2
Cowman, A.F.3
Kemp, D.J.4
-
28
-
-
0025269612
-
Several alleles of the multidrug resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
-
S.J. Foote, D.E. Kyle, R.K. Martin, A.M.J. Oduola, K. Forsyth, D.J. Kemp, and A.F. Cowman Several alleles of the multidrug resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum Nature 345 1990 255 258
-
(1990)
Nature
, vol.345
, pp. 255-258
-
-
Foote, S.J.1
Kyle, D.E.2
Martin, R.K.3
Oduola, A.M.J.4
Forsyth, K.5
Kemp, D.J.6
Cowman, A.F.7
-
29
-
-
0037015614
-
Genome sequence of the human malaria parasite Plasmodium falciparum
-
M.J. Gardner, N. Hall, E. Fung, O. White, M. Berriman, R.W. Hyman, J.M. Carlton, A. Pain, K.E. Nelson, S. Bowman, I.T. Paulsen, K. James, J.A. Eisen, K. Rutherford, S.L. Salzberg, A. Craig, S. Kyes, M.-S. Chan, V. Nene, S.J. Shallom, B. Suh, J. Peterson, S. Angiuoli, M. Pertea, J. Allen, J. Selengut, D. Haft, M.W. Mather, A.B. Vaidya, D.M.A. Martin, A.H. Fairlamb, M.J. Fraunholz, D.S. Roos, S.A. Ralph, G.I. Mcfadden, L.M. Cummings, G.M. Subramanian, C. Mungall, J.C. Venter, D.J. Carucci, S.L. Hoffman, C. Newbold, R.W. Davis, C.M. Fraser, and B. Barrell Genome sequence of the human malaria parasite Plasmodium falciparum Nature 419 2002 498 511
-
(2002)
Nature
, vol.419
, pp. 498-511
-
-
Gardner, M.J.1
Hall, N.2
Fung, E.3
White, O.4
Berriman, M.5
Hyman, R.W.6
Carlton, J.M.7
Pain, A.8
Nelson, K.E.9
Bowman, S.10
Paulsen, I.T.11
James, K.12
Eisen, J.A.13
Rutherford, K.14
Salzberg, S.L.15
Craig, A.16
Kyes, S.17
Chan, M.-S.18
Nene, V.19
Shallom, S.J.20
Suh, B.21
Peterson, J.22
Angiuoli, S.23
Pertea, M.24
Allen, J.25
Selengut, J.26
Haft, D.27
Mather, M.W.28
Vaidya, A.B.29
Martin, D.M.A.30
Fairlamb, A.H.31
Fraunholz, M.J.32
Roos, D.S.33
Ralph, S.A.34
McFadden, G.I.35
Cummings, L.M.36
Subramanian, G.M.37
Mungall, C.38
Venter, J.C.39
Carucci, D.J.40
Hoffman, S.L.41
Newbold, C.42
Davis, R.W.43
Fraser, C.M.44
Barrell, B.45
more..
-
30
-
-
0030602249
-
Overexpression of P-glycoprotein gene 1 by transfected Entamoeba histolytica confers emetine-resistance
-
S.K. Ghosh, A. Lohia, A. Kumar, and J. Samuelson Overexpression of P-glycoprotein gene 1 by transfected Entamoeba histolytica confers emetine-resistance Mol. Biochem. Parasitol. 82 1996 257 260
-
(1996)
Mol. Biochem. Parasitol.
, vol.82
, pp. 257-260
-
-
Ghosh, S.K.1
Lohia, A.2
Kumar, A.3
Samuelson, J.4
-
31
-
-
0026079215
-
Kinetic modelling of chloroquine uptake by malaria-infected erythrocytes: Assessment of the factors that may determine drug resistance
-
H. Ginsburg, and W.D. Stein Kinetic modelling of chloroquine uptake by malaria-infected erythrocytes: assessment of the factors that may determine drug resistance Biochem. Pharmacol. 41 1991 1463 1470
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 1463-1470
-
-
Ginsburg, H.1
Stein, W.D.2
-
32
-
-
0029565603
-
Leishmania amazonensis: Multidrug resistance in vinblastine-resistant promastigotesis associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr1 gene
-
F.J. Gueiros-Filho, J.P.B. Viola, F.C.A. Gomes, M. Farina, U. Lins, A.L. Bertho, D.F. Wirth, and U.G. Lopes Leishmania amazonensis: multidrug resistance in vinblastine-resistant promastigotesis associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr1 gene Exp. Parasitol. 81 1995 480 490
-
(1995)
Exp. Parasitol.
, vol.81
, pp. 480-490
-
-
Gueiros-Filho, F.J.1
Viola, J.P.B.2
Gomes, F.C.A.3
Farina, M.4
Lins, U.5
Bertho, A.L.6
Wirth, D.F.7
Lopes, U.G.8
-
33
-
-
0026720137
-
Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene
-
D.M. Henderson, C.D. Sifri, M. Rodgers, D.F. Wirth, N. Hendrickson, and B. Ullman Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene Mol. Cell Biol. 12 1992 2855 2865
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 2855-2865
-
-
Henderson, D.M.1
Sifri, C.D.2
Rodgers, M.3
Wirth, D.F.4
Hendrickson, N.5
Ullman, B.6
-
34
-
-
0033517487
-
Leishmaniasis
-
B.L. Herwaldt Leishmaniasis Lancet 354 1999 1191 1199
-
(1999)
Lancet
, vol.354
, pp. 1191-1199
-
-
Herwaldt, B.L.1
-
35
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
C.F. Higgins ABC transporters: from microorganisms to man Annu. Rev. Cell Biol. 8 1992 67 113
-
(1992)
Annu. Rev. Cell Biol.
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
37
-
-
0032790754
-
Identification and stage-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus
-
Y.-J. Huang, and R.K. Prichard Identification and stage-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus Mol. Biochem. Parasitol. 102 1999 273 281
-
(1999)
Mol. Biochem. Parasitol.
, vol.102
, pp. 273-281
-
-
Huang, Y.-J.1
Prichard, R.K.2
-
39
-
-
0345096564
-
Chloroquine resistance in Plasmodium chabaudi: Are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved?
-
P. Hunt, P.V.L. Cravo, P. Donleavy, J.M-R. Carlton, and D. Walliker Chloroquine resistance in Plasmodium chabaudi: are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved? Mol. Biochem. Parasitol. 133 2004 27 35
-
(2004)
Mol. Biochem. Parasitol.
, vol.133
, pp. 27-35
-
-
Hunt, P.1
Cravo, P.V.L.2
Donleavy, P.3
Carlton, J.M-R.4
Walliker, D.5
-
40
-
-
0036188538
-
Mechanism of resistance of Plasmodium falciparum to antimalarial drugs
-
J.E. Hyde Mechanism of resistance of Plasmodium falciparum to antimalarial drugs Microb. Infect. 4 2002 165 174
-
(2002)
Microb. Infect.
, vol.4
, pp. 165-174
-
-
Hyde, J.E.1
-
41
-
-
0034110796
-
The development of anthelmintic resistance in sheep nematodes
-
F. Jackson, and R.L. Coop The development of anthelmintic resistance in sheep nematodes Parasitology 120 2000 S95 S107
-
(2000)
Parasitology
, vol.120
-
-
Jackson, F.1
Coop, R.L.2
-
42
-
-
1842610700
-
The ABC transporter structure and mechanism: Perspectives on recent research
-
P.M. Jones, and A.M. George The ABC transporter structure and mechanism: perspectives on recent research Cell. Mol. Life Sci. 61 2004 682 699
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 682-699
-
-
Jones, P.M.1
George, A.M.2
-
44
-
-
0042764352
-
ABC transporters and drug resistance in parasitic protozoa
-
A. Klokouzas, S. Shahi, S.B. Hladky, M.A. Barrand, and H.W. van Veen ABC transporters and drug resistance in parasitic protozoa Int. J. Antimicrob. Agents 22 2003 301 317
-
(2003)
Int. J. Antimicrob. Agents
, vol.22
, pp. 301-317
-
-
Klokouzas, A.1
Shahi, S.2
Hladky, S.B.3
Barrand, M.A.4
Van Veen, H.W.5
-
45
-
-
0035068456
-
The biochemical basis of anthelmintic action and resistance
-
P. Köhler The biochemical basis of anthelmintic action and resistance Int. J. Parasitol. 31 2001 336 345
-
(2001)
Int. J. Parasitol.
, vol.31
, pp. 336-345
-
-
Köhler, P.1
-
46
-
-
0023666563
-
Efflux of chloroquine from Plasmodium falciparum: Mechanism of chloroquine resistance
-
D.J. Krogstad, I.Y. Gluzman, D.E. Kyle, O.M.J. Oduola, S.K. Martin, W.K. Milhous, and P.H. Schlesinger Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance Science 238 1987 1283 1285
-
(1987)
Science
, vol.238
, pp. 1283-1285
-
-
Krogstad, D.J.1
Gluzman, I.Y.2
Kyle, D.E.3
Oduola, O.M.J.4
Martin, S.K.5
Milhous, W.K.6
Schlesinger, P.H.7
-
47
-
-
0041331783
-
Leishmaniasis: Efflux pumps and chemoresistance
-
C. Leandro, and L. Campino Leishmaniasis: efflux pumps and chemoresistance Int. J. Antimicrobiol. Agents 22 2003 352 357
-
(2003)
Int. J. Antimicrobiol. Agents
, vol.22
, pp. 352-357
-
-
Leandro, C.1
Campino, L.2
-
48
-
-
0037396367
-
The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum
-
J. Le Bras, and R. Durand The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum Fundam. Clin. Pharmacol. 17 2003 147 153
-
(2003)
Fundam. Clin. Pharmacol.
, vol.17
, pp. 147-153
-
-
Le Bras, J.1
Durand, R.2
-
49
-
-
0035688926
-
ABC proteins in Leishmania
-
D. Légaré, S. Cayer, A.K. Singh, D. Richard, B. Papadopoulou, and M. Ouellette ABC proteins in Leishmania J. Bioenerg. Biomembr. 33 2001 469 474
-
(2001)
J. Bioenerg. Biomembr.
, vol.33
, pp. 469-474
-
-
Légaré, D.1
Cayer, S.2
Singh, A.K.3
Richard, D.4
Papadopoulou, B.5
Ouellette, M.6
-
50
-
-
0026618689
-
The P-glycoprotein gene family of Caenorhabditis elegans: Cloning and characterization of genomic and complementary DNA sequences
-
C.R. Lincke, I. The, M. van Groenigen, and P. Borst The P-glycoprotein gene family of Caenorhabditis elegans: cloning and characterization of genomic and complementary DNA sequences J. Mol. Biol. 228 1992 701 711
-
(1992)
J. Mol. Biol.
, vol.228
, pp. 701-711
-
-
Lincke, C.R.1
The, I.2
Van Groenigen, M.3
Borst, P.4
-
51
-
-
0033509735
-
Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani
-
R. Lira, S. Sundar, A. Makharia, R. Kenney, A. Gam, E. Saraiva, and D. Sacks Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani J. Infect. Dis. 180 1999 564 567
-
(1999)
J. Infect. Dis.
, vol.180
, pp. 564-567
-
-
Lira, R.1
Sundar, S.2
Makharia, A.3
Kenney, R.4
Gam, A.5
Saraiva, E.6
Sacks, D.7
-
52
-
-
0037052565
-
The E. coli BtuCD structure: A framework for ABC transporter architecture and mechanism
-
K.P. Locher, A.T. Lee, and D.C. Rees The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism Science 296 2002 1091 1098
-
(2002)
Science
, vol.296
, pp. 1091-1098
-
-
Locher, K.P.1
Lee, A.T.2
Rees, D.C.3
-
54
-
-
0031882865
-
Identification of three ABC transporter genes in Trypanosoma brucei spp
-
P. Mäser, and R. Kaminsky Identification of three ABC transporter genes in Trypanosoma brucei spp Parasitol. Res. 84 1998 106 111
-
(1998)
Parasitol. Res.
, vol.84
, pp. 106-111
-
-
Mäser, P.1
Kaminsky, R.2
-
55
-
-
0037834651
-
A nucleoside transporter from Trypanosoma brucei involved in drug resistance
-
P. Mäser, C. Sutterlin, A. Kralli, and R. Kaminsky A nucleoside transporter from Trypanosoma brucei involved in drug resistance Science 285 1999 242 244
-
(1999)
Science
, vol.285
, pp. 242-244
-
-
Mäser, P.1
Sutterlin, C.2
Kralli, A.3
Kaminsky, R.4
-
56
-
-
17444433224
-
Drug transport and drug resistance in African trypanosomes
-
P. Mäser, A. Lüscher, and R. Kaminsky Drug transport and drug resistance in African trypanosomes Drug Res. Updates 6 2003 281 290
-
(2003)
Drug Res. Updates
, vol.6
, pp. 281-290
-
-
Mäser, P.1
Lüscher, A.2
Kaminsky, R.3
-
57
-
-
10744226397
-
The mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei
-
E. Matovu, M.L. Stewart, F. Geiser, R. Brun, P. Mäser, L.J. Wallace, R.J. Burchmore, J.C. Enyaru, M.P. Barrett, R. Kaminsky, T. Seebeck, and H.P. de Koning The mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei Eukaryot. Cell 2 2003 1003 1008
-
(2003)
Eukaryot. Cell
, vol.2
, pp. 1003-1008
-
-
Matovu, E.1
Stewart, M.L.2
Geiser, F.3
Brun, R.4
Mäser, P.5
Wallace, L.J.6
Burchmore, R.J.7
Enyaru, J.C.8
Barrett, M.P.9
Kaminsky, R.10
Seebeck, T.11
De Koning, H.P.12
-
58
-
-
10744231302
-
Multiple transporters associated with malaria parasite responses to chloroquine and quinine
-
J. Mu, M.T. Ferdig, X. Feng, D.A. Joy, J. Duan, T. Furuya, G. Subramanian, L. Aravind, R.A. Cooper, J.C. Wootton, M. Xiong, and X.-z. Su Multiple transporters associated with malaria parasite responses to chloroquine and quinine Mol. Microbiol. 49 2003 977 989
-
(2003)
Mol. Microbiol.
, vol.49
, pp. 977-989
-
-
Mu, J.1
Ferdig, M.T.2
Feng, X.3
Joy, D.A.4
Duan, J.5
Furuya, T.6
Subramanian, G.7
Aravind, L.8
Cooper, R.A.9
Wootton, J.C.10
Xiong, M.11
Su, X.-Z.12
-
59
-
-
0034788472
-
Drug resistance in Trypanosoma cruzi is not associated with amplification or overexpression of P-glycoprotein (PGP) genes
-
S.M.F. Murta, W.G. dos Santos, C. Anacleto, P. Nirdé, E.S.A. Moreira, and A.J. Romanha Drug resistance in Trypanosoma cruzi is not associated with amplification or overexpression of P-glycoprotein (PGP) genes Mol. Biochem. Parasitol. 117 2001 223 228
-
(2001)
Mol. Biochem. Parasitol.
, vol.117
, pp. 223-228
-
-
Murta, S.M.F.1
Dos Santos, W.G.2
Anacleto, C.3
Nirdé, P.4
Moreira, E.S.A.5
Romanha, A.J.6
-
60
-
-
0035371224
-
Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria
-
T. Nomura, J.M.R. Carlton, J.K. Baird, H.A. del Portillo, D.J. Fryauff, D. Rathore, D.A. Fidock, X.-z. Su, W.E. Collins, T.F. McCutchan, J.C. Wootton, and T.E. Wellem Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria J. Infect. Dis. 183 2001 1653 1661
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 1653-1661
-
-
Nomura, T.1
Carlton, J.M.R.2
Baird, J.K.3
Del Portillo, H.A.4
Fryauff, D.J.5
Rathore, D.6
Fidock, D.A.7
Su, X.-Z.8
Collins, W.E.9
McCutchan, T.F.10
Wootton, J.C.11
Wellem, T.E.12
-
61
-
-
0034623005
-
T-coffee: A novel method for multiple sequence alignments
-
C. Notredame, D. Higgins, and J. Heringa T-coffee: a novel method for multiple sequence alignments J. Mol. Biol. 302 2000 205 217
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 205-217
-
-
Notredame, C.1
Higgins, D.2
Heringa, J.3
-
62
-
-
0034771312
-
Biochemical and molecular mechanisms of drug resistance in parasites
-
M. Ouellette Biochemical and molecular mechanisms of drug resistance in parasites Trop. Med. Int. Health 6 2001 874 882
-
(2001)
Trop. Med. Int. Health
, vol.6
, pp. 874-882
-
-
Ouellette, M.1
-
63
-
-
0025321675
-
The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene
-
M. Ouellette, F. Fase-Fowler, and P. Borst The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene Eur. Mol. Bio. Org. J. 9 1990 1027 1033
-
(1990)
Eur. Mol. Bio. Org. J.
, vol.9
, pp. 1027-1033
-
-
Ouellette, M.1
Fase-Fowler, F.2
Borst, P.3
-
65
-
-
0038730501
-
The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity
-
A. Parodi-Talice, J.M. Araújo, C. Torres, J.M. Pérez-Victoria, F. Gamarro, and S. Castanys The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity Biochim. Biophys. Acta 1612 2003 195 207
-
(2003)
Biochim. Biophys. Acta
, vol.1612
, pp. 195-207
-
-
Parodi-Talice, A.1
Araújo, J.M.2
Torres, C.3
Pérez-Victoria, J.M.4
Gamarro, F.5
Castanys, S.6
-
66
-
-
0035065294
-
The ABC transporter genes of Plasmodium falciparum and drug resistance
-
S.A. Peel The ABC transporter genes of Plasmodium falciparum and drug resistance Drug Res. Updates 4 2001 66 74
-
(2001)
Drug Res. Updates
, vol.4
, pp. 66-74
-
-
Peel, S.A.1
-
67
-
-
0028135205
-
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro
-
S.A. Peel, P. Bright, B. Yount, J. Handy, and R.S. Baric A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro Am. J. Trop. Med. Hyg. 51 1994 648 658
-
(1994)
Am. J. Trop. Med. Hyg.
, vol.51
, pp. 648-658
-
-
Peel, S.A.1
Bright, P.2
Yount, B.3
Handy, J.4
Baric, R.S.5
-
68
-
-
0035468512
-
ABC transporters in the protozoan parasite Leishmania
-
J.M. Perez-Victoria, A. Parodi-Talice, C. Torres, F. Gamarro, and S. Castanys ABC transporters in the protozoan parasite Leishmania Int. Microbiol. 4 2001 159 166
-
(2001)
Int. Microbiol.
, vol.4
, pp. 159-166
-
-
Perez-Victoria, J.M.1
Parodi-Talice, A.2
Torres, C.3
Gamarro, F.4
Castanys, S.5
-
69
-
-
0030828397
-
How do anthelmintics work?
-
R. Prichard How do anthelmintics work? Vet. J. 154 1997 5 7
-
(1997)
Vet. J.
, vol.154
, pp. 5-7
-
-
Prichard, R.1
-
70
-
-
0031841526
-
Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters
-
M.B. Reed, M. Panaccio, R.A. Strugnell, and T.W. Spithill Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters Int. J. Parasitol. 28 1998 1375 1381
-
(1998)
Int. J. Parasitol.
, vol.28
, pp. 1375-1381
-
-
Reed, M.B.1
Panaccio, M.2
Strugnell, R.A.3
Spithill, T.W.4
-
71
-
-
0034708162
-
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
-
M.B. Reed, K.J. Saliba, S.R. Caruana, K. Kirk, and A.F. Cowman Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum Nature 403 2000 906 909
-
(2000)
Nature
, vol.403
, pp. 906-909
-
-
Reed, M.B.1
Saliba, K.J.2
Caruana, S.R.3
Kirk, K.4
Cowman, A.F.5
-
72
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
A. Sali, and T.L. Blundell Comparative protein modelling by satisfaction of spatial restraints J. Mol. Biol. 234 1993 779 815
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
73
-
-
0042573722
-
Trans stimulation provides evidence for a drug efflux carrier as the mechanism of chloroquine resistance in Plasmodium falciparum
-
C.P. Sanchez, W. Stein, and M. Lanzer Trans stimulation provides evidence for a drug efflux carrier as the mechanism of chloroquine resistance in Plasmodium falciparum Biochemistry 42 2003 9383 9394
-
(2003)
Biochemistry
, vol.42
, pp. 9383-9394
-
-
Sanchez, C.P.1
Stein, W.2
Lanzer, M.3
-
74
-
-
0028074774
-
P-glycoprotein in nematodes
-
N.C. Sangster P-glycoprotein in nematodes Parasitol. Today 10 1994 310 322
-
(1994)
Parasitol. Today
, vol.10
, pp. 310-322
-
-
Sangster, N.C.1
-
75
-
-
0032893559
-
Anthelmintic resistance: Past, present and future
-
N.C. Sangster Anthelmintic resistance: past, present and future Int. J. Parasitol. 29 1999 115 124
-
(1999)
Int. J. Parasitol.
, vol.29
, pp. 115-124
-
-
Sangster, N.C.1
-
76
-
-
0028229150
-
Disruption of the mouse mdr-1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
A.H. Schinkel, J.J.M. Smit, O. Van Tellingen, J.H. Beijnen, E.E. Wanenaar, E. Van Deemter, C.A.A.M. Mol, M.A. Van der Valk, E.C. Robanus-Maandag, H.P.J. Te Riele, A.J.M. Berns, and P. Borst Disruption of the mouse mdr-1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Cell 77 1994 491 502
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wanenaar, E.E.5
Van Deemter, E.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
77
-
-
0042622380
-
SWISS-MODEL: An automated protein homology-modeling server
-
T. Schwede, J. Kopp, N. Guex, and M.C. Peitsch SWISS-MODEL: an automated protein homology-modeling server Nucleic Acids Res. 31 2003 3381 3385
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3381-3385
-
-
Schwede, T.1
Kopp, J.2
Guex, N.3
Peitsch, M.C.4
-
78
-
-
0036223214
-
Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei
-
S.K. Shahi, R.L. Krauth-Siegel, and C.E. Clayton Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei Mol. Microbiol. 43 2002 1129 1138
-
(2002)
Mol. Microbiol.
, vol.43
, pp. 1129-1138
-
-
Shahi, S.K.1
Krauth-Siegel, R.L.2
Clayton, C.E.3
-
79
-
-
0029784872
-
Secondary and tertiary structure changes of reconstituted P-glycoprotein - A Fourier transform attenuated total reflection infrared spectroscopy analysis
-
N. Sonveaux, A.B. Shapiro, E. Goormaghtigh, V. Ling, and J.-M. Ruysschaert Secondary and tertiary structure changes of reconstituted P-glycoprotein - a Fourier transform attenuated total reflection infrared spectroscopy analysis J. Biol. Chem. 271 1996 24617 24624
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24617-24624
-
-
Sonveaux, N.1
Shapiro, A.B.2
Goormaghtigh, E.3
Ling, V.4
Ruysschaert, J.-M.5
-
80
-
-
0642272487
-
An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulphide cross-linking and homology modeling
-
D.R. Stenham, J.D. Campbell, M.S.P. Sansom, C.F. Higgins, I.D. Kerr, and K.J. Linton An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulphide cross-linking and homology modeling Fed. Am. Soc. Exp. Biol. J. 17 2003 2287 2289
-
(2003)
Fed. Am. Soc. Exp. Biol. J.
, vol.17
, pp. 2287-2289
-
-
Stenham, D.R.1
Campbell, J.D.2
Sansom, M.S.P.3
Higgins, C.F.4
Kerr, I.D.5
Linton, K.J.6
-
81
-
-
0034451615
-
Failure of pentavalent antimony in visceral leishmaniasis in India: Report from the center of the Indian epidemic
-
S. Sundar, D.K. More, M.K. Singh, V.P. Singh, S. Sharma, A. Makaria, P.C. Kumar, and H.W. Murray Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic Clin. Infect. Dis. 31 2000 1104 1107
-
(2000)
Clin. Infect. Dis.
, vol.31
, pp. 1104-1107
-
-
Sundar, S.1
More, D.K.2
Singh, M.K.3
Singh, V.P.4
Sharma, S.5
Makaria, A.6
Kumar, P.C.7
Murray, H.W.8
-
82
-
-
2142657830
-
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum
-
R.F. Trotta, M.L. Brown, J.C. Terrel, and J.A. Geyer Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum Biochemistry 43 2004 4885 4891
-
(2004)
Biochemistry
, vol.43
, pp. 4885-4891
-
-
Trotta, R.F.1
Brown, M.L.2
Terrel, J.C.3
Geyer, J.A.4
-
83
-
-
0032518394
-
A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene
-
H.W. van Veen, R. Callaghan, L. Soceneantu, A. Sardini, W.N. Konings, and C.F. Higgins A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene Nature 391 1998 291 295
-
(1998)
Nature
, vol.391
, pp. 291-295
-
-
Van Veen, H.W.1
Callaghan, R.2
Soceneantu, L.3
Sardini, A.4
Konings, W.N.5
Higgins, C.F.6
-
84
-
-
0034646645
-
Secondary and tertiary structure changes of reconstituted LmrA induced by nucleotide binding or hydrolysis
-
C. Vigano, A. Margolles, H.W. van Veen, W.N. Konings, and J.-M. Ruysschaert Secondary and tertiary structure changes of reconstituted LmrA induced by nucleotide binding or hydrolysis J. Biol. Chem. 275 2000 10962 10967
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10962-10967
-
-
Vigano, C.1
Margolles, A.2
Van Veen, H.W.3
Konings, W.N.4
Ruysschaert, J.-M.5
-
85
-
-
4644374002
-
Molecular and cellular biology of chloroquine resistance in Plasmodium falciparum
-
A.P. Waters C.J. Janse Caister Academic Press Wymondham
-
K.L. Waller, S. Lee, and D.A. Fidock Molecular and cellular biology of chloroquine resistance in Plasmodium falciparum A.P. Waters C.J. Janse Malarial Parasites 2004 Caister Academic Press Wymondham 501 540
-
(2004)
Malarial Parasites
, pp. 501-540
-
-
Waller, K.L.1
Lee, S.2
Fidock, D.A.3
-
86
-
-
0029062531
-
Current views on the mechanisms of resistance to quinolone-containing drugs in Plasmodium falciparum
-
S.A. Ward, P.G. Bray, M. Mungthin, and S.R. Hawley Current views on the mechanisms of resistance to quinolone-containing drugs in Plasmodium falciparum Ann. Trop. Med. Parasitol. 89 1995 121 124
-
(1995)
Ann. Trop. Med. Parasitol.
, vol.89
, pp. 121-124
-
-
Ward, S.A.1
Bray, P.G.2
Mungthin, M.3
Hawley, S.R.4
-
87
-
-
0031752556
-
Drug resistance in malaria
-
N.J. White Drug resistance in malaria Br. Med. J. 54 1998 703 715
-
(1998)
Br. Med. J.
, vol.54
, pp. 703-715
-
-
White, N.J.1
-
88
-
-
0002426221
-
Review of chemotherapeutic and chemoprophylactic agents
-
H.W. Mulligan George Allen and Unwin Ltd London
-
J. Williamson Review of chemotherapeutic and chemoprophylactic agents H.W. Mulligan The African Trypanosomes 1970 George Allen and Unwin Ltd London 125 221
-
(1970)
The African Trypanosomes
, pp. 125-221
-
-
Williamson, J.1
-
89
-
-
0024356582
-
Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
-
C.M. Wilson, A.E. Serrano, A. Wasley, M.P. Boganschutz, A.H. Shankar, and D.F. Wirth Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum Science 244 1989 1184 1186
-
(1989)
Science
, vol.244
, pp. 1184-1186
-
-
Wilson, C.M.1
Serrano, A.E.2
Wasley, A.3
Boganschutz, M.P.4
Shankar, A.H.5
Wirth, D.F.6
-
90
-
-
0037020172
-
Illumination of the malaria parasite Plasmodium falciparum alters intracellular pH
-
F. Wissing, C.P. Sanchez, P. Rohrbach, S. Ricken, and M. Lanzar Illumination of the malaria parasite Plasmodium falciparum alters intracellular pH J. Biol. Chem. 277 2002 37747 37755
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37747-37755
-
-
Wissing, F.1
Sanchez, C.P.2
Rohrbach, P.3
Ricken, S.4
Lanzar, M.5
-
91
-
-
0032520963
-
Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog
-
M. Xu, M. Molento, W. Blackhall, P. Ribeiro, R. Beech, and R. Prichard Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog Mol. Biochem. Parasitol. 91 1998 327 335
-
(1998)
Mol. Biochem. Parasitol.
, vol.91
, pp. 327-335
-
-
Xu, M.1
Molento, M.2
Blackhall, W.3
Ribeiro, P.4
Beech, R.5
Prichard, R.6
|