The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling

Biochemistry

Volumn 48, Issue 43, 2009, Pages 10267-10274

  Chen, Minyong ^a   Wang, Jiangbo ^a   Lu, Jiuyi ^a   Bond, Michael C ^a   Ren, Xiu Rong ^a   Lyerly, H Kim ^b   Barak, Larry S ^b   Chen, Wei ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; DRUG CANDIDATES; FLUORESCENCE ASSAY; RECEPTOR TRAFFICKING; REGENERATIVE EFFECTS; SIGNALING MOLECULES; STEM CELL; TRANSMEMBRANES; WNT SIGNALING;

CELL MEMBRANES; ENZYME INHIBITION; MODULATORS;

SIGNALING;

BETA 2 ADRENERGIC RECEPTOR; BETA CATENIN; DISHEVELLED 2; GREEN FLUORESCENT PROTEIN; NICLOSAMIDE; SECRETED FRIZZLED RELATED PROTEIN 1; T CELL FACTOR PROTEIN; TRANSFERRIN; WNT PROTEIN; WNT3A PROTEIN;

ANTHELMINTIC ACTIVITY; ARTICLE; CESTODE; DOWN REGULATION; DRUG INHIBITION; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENDOCYTOSIS; FLUORESCENCE ANALYSIS; FOOD AND DRUG ADMINISTRATION; HUMAN; HUMAN CELL; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANIMALS; ANTINEMATODAL AGENTS; BETA CATENIN; CELL LINE; CELL LINE, TUMOR; ENDOCYTOSIS; FRIZZLED RECEPTORS; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSCOPY, CONFOCAL; NICLOSAMIDE; RATS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 70350489312     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9009677     Document Type: Article

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