-
1
-
-
33747071746
-
The prevention and treatment of metabolic syndrome and high-risk obesity
-
Molavi B, Rasouli N, Kern PA. The prevention and treatment of metabolic syndrome and high-risk obesity. Curr Opin Cardiol 2006;21(5):479-85
-
(2006)
Curr Opin Cardiol
, vol.21
, Issue.5
, pp. 479-485
-
-
Molavi, B.1
Rasouli, N.2
Kern, P.A.3
-
2
-
-
39149104320
-
The role for endoplasmic reticulum stress in diabetes mellitus
-
Eizirik DL, Cardozo AK, Cnop M. The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 2008;29(1):42-61
-
(2008)
Endocr Rev
, vol.29
, Issue.1
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
3
-
-
0027947379
-
Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships
-
Lee Y, Hirose H, Ohneda M, et al. Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci USA 1994;91(23):10878-82
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.23
, pp. 10878-10882
-
-
Lee, Y.1
Hirose, H.2
Ohneda, M.3
-
4
-
-
12444334643
-
Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation
-
Lelliott C, Vidal-Puig AJ. Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation. Int J Obes Relat Metab Disord 2004;28(Suppl 4):S22-8
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, Issue.SUPPL. 4
-
-
Lelliott, C.1
Vidal-Puig, A.J.2
-
5
-
-
0033694535
-
Lipotoxic diseases of nonadipose tissues in obesity
-
Unger RH, Orci L. Lipotoxic diseases of nonadipose tissues in obesity. Int J Obes Relat Metab Disord 2000;24(Suppl 4):S28-32
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, Issue.SUPPL. 4
-
-
Unger, R.H.1
Orci, L.2
-
6
-
-
54749114466
-
It's not how fat you are, it's what you do with it that counts
-
Virtue S, Vidal-Puig A. It's not how fat you are, it's what you do with it that counts. PLoS Biol 2008;6(9):e237
-
(2008)
PLoS Biol
, vol.6
, Issue.9
-
-
Virtue, S.1
Vidal-Puig, A.2
-
7
-
-
0034652225
-
Lipotoxic heart disease in obese rats: Implications for human obesity
-
Zhou YT, Grayburn P, Karim A, et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci USA 2000;97(4):1784-9
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.4
, pp. 1784-1789
-
-
Zhou, Y.T.1
Grayburn, P.2
Karim, A.3
-
8
-
-
33845864967
-
Adipocytes as regulators of energy balance and glucose homeostasis
-
Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006;444(7121):847-53
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 847-853
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
9
-
-
77249131674
-
Hypothalamic nutrient sensing in the control of energy homeostasis
-
Blouet C, Schwartz GJ. Hypothalamic nutrient sensing in the control of energy homeostasis. Behav Brain Res 2010;209(1):1-12
-
(2010)
Behav Brain Res
, vol.209
, Issue.1
, pp. 1-12
-
-
Blouet, C.1
Schwartz, G.J.2
-
10
-
-
33845549453
-
Fatty acid signaling in the hypothalamus and the neural control of insulin secretion
-
Migrenne S, Cruciani-Guglielmacci C, Kang L, et al. Fatty acid signaling in the hypothalamus and the neural control of insulin secretion. Diabetes 2006;55:S139-S44
-
(2006)
Diabetes
, vol.55
-
-
Migrenne, S.1
Cruciani-Guglielmacci, C.2
Kang, L.3
-
11
-
-
11844282198
-
Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons
-
Hayashi T, Saito A, Okuno S, et al. Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons. J Cereb Blood Flow Metab 2005;25(1):41-53
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, Issue.1
, pp. 41-453
-
-
Hayashi, T.1
Saito, A.2
Okuno, S.3
-
12
-
-
34147170083
-
Involvement of ER stress in retinal cell death
-
Shimazawa M, Inokuchi Y, Ito Y, et al. Involvement of ER stress in retinal cell death. Mol Vis 2007;13:578-87
-
(2007)
Mol Vis
, vol.13
, pp. 578-587
-
-
Shimazawa, M.1
Inokuchi, Y.2
Ito, Y.3
-
13
-
-
0035315659
-
Brain uptake and utilization of fatty acids: Applications to peroxisomal biogenesis diseases
-
discussion 151-157
-
Watkins PA, Hamilton JA, Leaf A, et al. Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases. J Mol Neurosci 2001;16(2-3):87-92; discussion 151-7
-
(2001)
J Mol Neurosci
, vol.16
, Issue.2
, pp. 387-392
-
-
Watkins, P.A.1
Hamilton, J.A.2
Leaf, A.3
-
14
-
-
0034912811
-
Essential polyunsaturated fatty acids and the barrier to the brain: The components of a model for transport
-
discussion 215-21
-
Edmond J. Essential polyunsaturated fatty acids and the barrier to the brain: the components of a model for transport. J Mol Neurosci 2001;16(2-3):181-93; discussion 215-21
-
(2001)
J Mol Neurosci
, vol.16
, Issue.2-3
, pp. 181-193
-
-
Edmond, J.1
-
15
-
-
0034988945
-
Delivery and turnover of plasma-derived essential PUFAs in mammalian brain
-
Rapoport SI, Chang MC, Spector AA. Delivery and turnover of plasma-derived essential PUFAs in mammalian brain. J Lipid Res 2001;42(5):678-85
-
(2001)
J Lipid Res
, vol.42
, Issue.5
, pp. 678-685
-
-
Rapoport, S.I.1
Chang, M.C.2
Spector, A.A.3
-
16
-
-
0034913792
-
Fatty acid uptake and incorporation in brain: Studies with the perfusion model
-
discussion 215-221
-
Smith QR, Nagura H. Fatty acid uptake and incorporation in brain: studies with the perfusion model. J Mol Neurosci 2001;16(2-3):167-72; discussion 215-21
-
(2001)
J Mol Neurosci
, vol.16
, Issue.2
, pp. 3167-3172
-
-
Smith, Q.R.1
Nagura, H.2
-
19
-
-
0034912915
-
In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling
-
discussion 79-84
-
Rapoport SI. In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling. J Mol Neurosci 2001;16(2-3):243-61; discussion 79-84
-
(2001)
J Mol Neurosci
, vol.16
, Issue.2-3
, pp. 243-261
-
-
Rapoport, S.I.1
-
20
-
-
0023636723
-
Utilization of plasma fatty acid in rat brain: Distribution of [14C]palmitate between oxidative and synthetic pathways
-
Miller JC, Gnaedinger JM, Rapoport SI. Utilization of plasma fatty acid in rat brain: distribution of [14C]palmitate between oxidative and synthetic pathways. J Neurochem 1987;49(5):1507-14
-
(1987)
J Neurochem
, vol.49
, Issue.5
, pp. 1507-1514
-
-
Miller, J.C.1
Gnaedinger, J.M.2
Rapoport, S.I.3
-
21
-
-
0029915866
-
In vivo labeling of brain phospholipids by long-chain fatty acids: Relation to turnover and function
-
Rapoport SI. In vivo labeling of brain phospholipids by long-chain fatty acids: relation to turnover and function. Lipids 1996;31(Suppl):S97-101
-
(1996)
Lipids
, vol.31
, Issue.SUPPL.
-
-
Rapoport, S.I.1
-
22
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott NJ, Ronnback L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 2006;7(1):41-53
-
(2006)
Nat Rev Neurosci
, vol.7
, Issue.1
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
23
-
-
78650862930
-
Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity
-
Wang H, Astarita G, Taussig MD, et al. Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metab 2011;13(1):105-13
-
(2011)
Cell Metab
, vol.13
, Issue.1
, pp. 105-113
-
-
Wang, H.1
Astarita, G.2
Taussig, M.D.3
-
24
-
-
69249089757
-
Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing
-
R664
-
Le Foll C, Irani BG, Magnan C, et al. Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing. Am J Physiol Regul Integr Comp Physiol 2009;297(3):R655-64
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.297
, Issue.3
-
-
Le Foll, C.1
Irani, B.G.2
Magnan, C.3
-
25
-
-
0030467446
-
The OB protein (leptin) pathway-a link between adipose tissue mass and central neural networks
-
Campfield LA, Smith FJ, Burn P. The OB protein (leptin) pathway-a link between adipose tissue mass and central neural networks. Horm Metab Res 1996;28(12):619-32
-
(1996)
Horm Metab Res
, vol.28
, Issue.12
, pp. 619-632
-
-
Campfield, L.A.1
Smith, F.J.2
Burn, P.3
-
26
-
-
84961007011
-
Regulation of energy intake and the body weight: The glucostatic theory and the lipostatic hypothesis
-
Mayer J. Regulation of energy intake and the body weight: the glucostatic theory and the lipostatic hypothesis. Ann NY Acad Sci 1955;63(1):15-43
-
(1955)
Ann NY Acad Sci
, vol.63
, Issue.1
, pp. 15-43
-
-
Mayer, J.1
-
27
-
-
0016814940
-
Effect of free fatty acid on the rat lateral hypothalamic neurons
-
Oomura Y, Nakamura T, Sugimori M, Yamada Y. Effect of free fatty acid on the rat lateral hypothalamic neurons. Physiol Behav 1975;14(04):483-6
-
(1975)
Physiol Behav
, vol.14
, Issue.4
, pp. 483-486
-
-
Oomura, Y.1
Nakamura, T.2
Sugimori, M.3
Yamada, Y.4
-
28
-
-
33646012618
-
Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels
-
Wang R, Cruciani-Guglielmacci C, Migrenne S, et al. Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels. J Neurophysiol 2006;95(3):1491-8
-
(2006)
J Neurophysiol
, vol.95
, Issue.3
, pp. 1491-1498
-
-
Wang, R.1
Cruciani-Guglielmacci, C.2
Migrenne, S.3
-
29
-
-
0036452672
-
Intracerebroventricular infusion of a triglyceride emulsion leads to both altered insulin secretion and hepatic glucose production in rats
-
Clement L, Cruciani-Guglielmacci C, Magnan C, et al. Intracerebroventricular infusion of a triglyceride emulsion leads to both altered insulin secretion and hepatic glucose production in rats. Pflugers Arch 2002;445(3):375-80
-
(2002)
Pflugers Arch
, vol.445
, Issue.3
, pp. 375-380
-
-
Clement, L.1
Cruciani-Guglielmacci, C.2
Magnan, C.3
-
30
-
-
77957550128
-
Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production
-
E639
-
Ross RA, Rossetti L, Lam TK, Schwartz GJ. Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. Am J Physiol Endocrinol Metab 2010;299(4):E633-9
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, Issue.4
-
-
Ross, R.A.1
Rossetti, L.2
Lam, T.K.3
Schwartz, G.J.4
-
31
-
-
0036065628
-
Central administration of oleic acid inhibits glucose production and food intake
-
Obici S, Feng Z, Morgan K, et al. Central administration of oleic acid inhibits glucose production and food intake. Diabetes 2002;51(2):271-5
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 271-275
-
-
Obici, S.1
Feng, Z.2
Morgan, K.3
-
32
-
-
0038037734
-
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
-
Obici S, Feng Z, Arduini A, et al. Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nat Med 2003;9(6):756-61
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 756-761
-
-
Obici, S.1
Feng, Z.2
Arduini, A.3
-
33
-
-
79952697164
-
Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism
-
Schwinkendorf DR, Tsatsos NG, Gosnell BA, Mashek DG. Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism. Int J Obes (Lond) 2011;35(3):336-44
-
(2011)
Int J Obes (Lond)
, vol.35
, Issue.3
, pp. 336-344
-
-
Schwinkendorf, D.R.1
Tsatsos, N.G.2
Gosnell, B.A.3
Mashek, D.G.4
-
34
-
-
16244388931
-
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
-
Lam TK, Pocai A, Gutierrez-Juarez R, et al. Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis. Nat Med 2005;11(3):320-7
-
(2005)
Nat Med
, vol.11
, Issue.3
, pp. 320-327
-
-
Lam, T.K.1
Pocai, A.2
Gutierrez-Juarez, R.3
-
35
-
-
3843114555
-
Hypothalamic responses to long-chain fatty acids are nutritionally regulated
-
Morgan K, Obici S, Rossetti L. Hypothalamic responses to long-chain fatty acids are nutritionally regulated. J Biol Chem 2004;279(30):31139-48
-
(2004)
J Biol Chem
, vol.279
, Issue.30
, pp. 31139-31148
-
-
Morgan, K.1
Obici, S.2
Rossetti, L.3
-
36
-
-
0032960430
-
Lipid infusion lowers sympathetic nervous activity and leads to increased beta-cell responsiveness to glucose
-
Magnan C, Collins S, Berthault MF, et al. Lipid infusion lowers sympathetic nervous activity and leads to increased beta-cell responsiveness to glucose. J Clin Invest 1999;103(3):413-19
-
(1999)
J Clin Invest
, vol.103
, Issue.3
, pp. 413-419
-
-
Magnan, C.1
Collins, S.2
Berthault, M.F.3
-
37
-
-
12144268025
-
Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats
-
Cruciani-Guglielmacci C, Hervalet A, Douared L, et al. Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats. Diabetologia 2004;47(11):2032-8
-
(2004)
Diabetologia
, vol.47
, Issue.11
, pp. 2032-2038
-
-
Cruciani-Guglielmacci, C.1
Hervalet, A.2
Douared, L.3
-
38
-
-
77954527315
-
The central nervous system at the core of the regulation of energy homeostasis
-
Luquet S, Magnan C. The central nervous system at the core of the regulation of energy homeostasis. Front Biosci (Schl Ed) 2009;1:448-65
-
(2009)
Front Biosci (Schl Ed)
, vol.1
, pp. 448-465
-
-
Luquet, S.1
Magnan, C.2
-
39
-
-
33645531123
-
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats
-
Pocai A, Lam TK, Obici S, et al. Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J Clin Invest 2006;116(4):1081-91
-
(2006)
J Clin Invest
, vol.116
, Issue.4
, pp. 1081-1091
-
-
Pocai, A.1
Lam, T.K.2
Obici, S.3
-
40
-
-
0020726951
-
Altered sympathetic activity during development of diet-induced obesity in rat
-
R355
-
Levin BE, Triscari J, Sullivan AC. Altered sympathetic activity during development of diet-induced obesity in rat. Am J Physiol 1983;244(3):R347-55
-
(1983)
Am J Physiol
, vol.244
, Issue.3
-
-
Levin, B.E.1
Triscari, J.2
Sullivan, A.C.3
-
41
-
-
0028013286
-
Differential effects of dietary fats on sympathetic nervous system activity in the rat
-
Young JB, Walgren MC. Differential effects of dietary fats on sympathetic nervous system activity in the rat. Metabolism 1994;43(1):51-60
-
(1994)
Metabolism
, vol.43
, Issue.1
, pp. 51-60
-
-
Young, J.B.1
Walgren, M.C.2
-
43
-
-
0023912682
-
Body fat and the activity of the autonomic nervous system
-
Peterson HR, Rothschild M, Weinberg CR, et al. Body fat and the activity of the autonomic nervous system. N Engl J Med 1988;318(17):1077-83
-
(1988)
N Engl J Med
, vol.318
, Issue.17
, pp. 1077-1083
-
-
Peterson, H.R.1
Rothschild, M.2
Weinberg, C.R.3
-
44
-
-
0242300121
-
Hypothalamic malonyl-CoA as a mediator of feeding behavior
-
Hu Z, Cha SH, Chohnan S, Lane MD. Hypothalamic malonyl-CoA as a mediator of feeding behavior. Proc Natl Acad Sci USA 2003;100(22):12624-9
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.22
, pp. 12624-12629
-
-
Hu, Z.1
Cha, S.H.2
Chohnan, S.3
Lane, M.D.4
-
45
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
Loftus TM, Jaworsky DE, Frehywot GL, et al. Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science 2000;288(5475):2379-81
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, G.L.3
-
46
-
-
33745294817
-
Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA
-
Lopez M, Lelliott CJ, Tovar S, et al. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. Diabetes 2006;55(5):1327-36
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1327-1336
-
-
Lopez, M.1
Lelliott, C.J.2
Tovar, S.3
-
47
-
-
50049123341
-
Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA
-
Lane MD, Wolfgang M, Cha SH, Dai Y. Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA. Int J Obes (Lond) 2008;32(Suppl 4):S49-54
-
(2008)
Int J Obes (Lond
, vol.32
, Issue.SUPPL. 4
-
-
Lane, M.D.1
Wolfgang, M.2
Cha, S.H.3
Dai, Y.4
-
48
-
-
0037610811
-
Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem
-
Gao S, Lane MD. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci USA 2003;100(10):5628-33
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.10
, pp. 5628-5633
-
-
Gao, S.1
Lane, M.D.2
-
49
-
-
0037039456
-
Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides
-
Shimokawa T, Kumar MV, Lane MD. Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides. Proc Natl Acad Sci USA 2002;99(1):66-71
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.1
, pp. 66-71
-
-
Shimokawa, T.1
Kumar, M.V.2
Lane, M.D.3
-
50
-
-
11144228934
-
C75 alters central and peripheral gene expression to reduce food intake and increase energy expenditure
-
Tu Y, Thupari JN, Kim EK, et al. C75 alters central and peripheral gene expression to reduce food intake and increase energy expenditure. Endocrinology 2005;146(1):486-93
-
(2005)
Endocrinology
, vol.146
, Issue.1
, pp. 486-493
-
-
Tu, Y.1
Thupari, J.N.2
Kim, E.K.3
-
51
-
-
42949146633
-
Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin
-
Lopez M, Lage R, Saha AK, et al. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. Cell Metab 2008;7(5):389-99
-
(2008)
Cell Metab
, vol.7
, Issue.5
, pp. 389-399
-
-
Lopez, M.1
Lage, R.2
Saha, A.K.3
-
52
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y, Alquier T, Furukawa N, et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004;428(6982):569-74
-
(2004)
Nature
, vol.428
, Issue.6982
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
-
53
-
-
34547651092
-
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
-
Claret M, Smith MA, Batterham RL, et al. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest 2007;117(8):2325-36
-
(2007)
J Clin Invest
, vol.117
, Issue.8
, pp. 2325-2336
-
-
Claret, M.1
Smith, M.A.2
Batterham, R.L.3
-
54
-
-
65649115847
-
Oleic acid directly regulates POMC neuron excitability in the hypothalamus
-
Jo YH, Su Y, Gutierrez-Juarez R, Chua S Jr. Oleic acid directly regulates POMC neuron excitability in the hypothalamus. J Neurophysiol 2009;101(5):2305-16
-
(2009)
J Neurophysiol
, vol.101
, Issue.5
, pp. 2305-2316
-
-
Jo, Y.H.1
Su, Y.2
Gutierrez-Juarez, R.3
Chua Jr., S.4
-
55
-
-
43249126281
-
The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse
-
Gaillard D, Laugerette F, Darcel N, et al. The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse. FASEB J 2008;22(5):1458-68
-
(2008)
FASEB J
, vol.22
, Issue.5
, pp. 1458-1468
-
-
Gaillard, D.1
Laugerette, F.2
Darcel, N.3
-
56
-
-
0032875098
-
Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
-
Resh MD. Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim Biophys Acta 1999;1451(1):1-16
-
(1999)
Biochim Biophys Acta
, vol.1451
, Issue.1
, pp. 1-16
-
-
Resh, M.D.1
-
57
-
-
27644484061
-
Autophagy: Molecular machinery for self-eating
-
Yorimitsu T, Klionsky DJ. Autophagy: molecular machinery for self-eating. Cell Death Differ 2005;12(Suppl 2):1542-52
-
(2005)
Cell Death Differ
, vol.12
, Issue.SUPPL. 2
, pp. 1542-1552
-
-
Yorimitsu, T.1
Klionsky, D.J.2
-
58
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008;132(1):27-42
-
(2008)
Cell
, vol.132
, Issue.1
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
59
-
-
79960951346
-
Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance
-
Kaushik S, Rodriguez-Navarro JA, Arias E, et al. Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance. Cell Metab 2011;14(2):173-83
-
(2011)
Cell Metab
, vol.14
, Issue.2
, pp. 173-183
-
-
Kaushik, S.1
Rodriguez-Navarro, J.A.2
Arias, E.3
-
60
-
-
84856953003
-
Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation
-
Coupe B, Ishii Y, Dietrich MO, et al. Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation. Cell Metab 2012;15(2):247-55
-
(2012)
Cell Metab
, vol.15
, Issue.2
, pp. 247-255
-
-
Coupe, B.1
Ishii, Y.2
Dietrich, M.O.3
-
61
-
-
84863229947
-
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis
-
Kaushik S, Arias E, Kwon H, et al. Loss of autophagy in hypothalamic POMC neurons impairs lipolysis. EMBO Rep 2012;13(3):258-65
-
(2012)
EMBO Rep
, vol.13
, Issue.3
, pp. 258-265
-
-
Kaushik, S.1
Arias, E.2
Kwon, H.3
-
62
-
-
84859416906
-
Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response
-
Quan W, Kim HK, Moon EY, et al. Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response. Endocrinology 2012;153(4):1817-26
-
(2012)
Endocrinology
, vol.153
, Issue.4
, pp. 1817-1826
-
-
Quan, W.1
Kim, H.K.2
Moon, E.Y.3
-
63
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444(7121):860-7
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
64
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
Zhang X, Zhang G, Zhang H, et al. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 2008;135(1):61-73
-
(2008)
Cell
, vol.135
, Issue.1
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
-
65
-
-
41749108854
-
Endoplasmic reticulum stress in disease pathogenesis
-
Lin JH, Walter P, Yen TS. Endoplasmic reticulum stress in disease pathogenesis. Annu Rev Pathol 2008;3:399-425
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 399-425
-
-
Lin, J.H.1
Walter, P.2
Yen, T.S.3
-
66
-
-
1842843855
-
Roles of CHOP/ GADD153 in endoplasmic reticulum stress
-
Oyadomari S, Mori M. Roles of CHOP/ GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004;11(4):381-9
-
(2004)
Cell Death Differ
, vol.11
, Issue.4
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
67
-
-
37649016171
-
How IRE1 reacts to ER stress
-
Ron D, Hubbard SR. How IRE1 reacts to ER stress. Cell 2008;132(1):24-6
-
(2008)
Cell
, vol.132
, Issue.1
, pp. 24-26
-
-
Ron, D.1
Hubbard, S.R.2
-
68
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007;8(7):519-29
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
69
-
-
56749112559
-
Endoplasmic reticulum stress induces leptin resistance
-
Hosoi T, Sasaki M, Miyahara T, et al. Endoplasmic reticulum stress induces leptin resistance. Mol Pharmacol 2008;74(6):1610-19
-
(2008)
Mol Pharmacol
, vol.74
, Issue.6
, pp. 1610-1619
-
-
Hosoi, T.1
Sasaki, M.2
Miyahara, T.3
-
70
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
Ozcan L, Ergin AS, Lu A, et al. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab 2009;9(1):35-51
-
(2009)
Cell Metab
, vol.9
, Issue.1
, pp. 35-51
-
-
Ozcan, L.1
Ergin, A.S.2
Lu, A.3
-
71
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010;140(6):900-17
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
72
-
-
80052712323
-
Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway
-
Meng Q, Cai D. Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway. J Biol Chem 2011;286(37):32324-32
-
(2011)
J Biol Chem
, vol.286
, Issue.37
, pp. 32324-32332
-
-
Meng, Q.1
Cai, D.2
-
73
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006;443(7113):787-95
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
74
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005;120(4):483-95
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
75
-
-
4544307465
-
Modeling mitochondrial function in aging neurons
-
Melov S. Modeling mitochondrial function in aging neurons. Trends Neurosci 2004;27(10):601-6
-
(2004)
Trends Neurosci
, vol.27
, Issue.10
, pp. 601-606
-
-
Melov, S.1
-
76
-
-
33847065926
-
Role for mitochondrial reactive oxygen species in brain lipid sensing: Redox regulation of food intake
-
Benani A, Troy S, Carmona MC, et al. Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake. Diabetes 2007;56(1):152-60
-
(2007)
Diabetes
, vol.56
, Issue.1
, pp. 152-160
-
-
Benani, A.1
Troy, S.2
Carmona, M.C.3
-
77
-
-
0036421318
-
A novel brain-expressed protein related to carnitine palmitoyltransferase i
-
Price N, van der Leij F, Jackson V, et al. A novel brain-expressed protein related to carnitine palmitoyltransferase I. Genomics 2002;80(4):433-42
-
(2002)
Genomics
, vol.80
, Issue.4
, pp. 433-442
-
-
Price, N.1
Van Der Leij, F.2
Jackson, V.3
-
78
-
-
33646576512
-
The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis
-
Wolfgang MJ, Kurama T, Dai Y, et al. The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. Proc Natl Acad Sci USA 2006;103(19):7282-7
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.19
, pp. 7282-7287
-
-
Wolfgang, M.J.1
Kurama, T.2
Dai, Y.3
-
79
-
-
43749088942
-
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
-
Sierra AY, Gratacos E, Carrasco P, et al. CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity. J Biol Chem 2008;283(11):6878-85
-
(2008)
J Biol Chem
, vol.283
, Issue.11
, pp. 6878-6885
-
-
Sierra, A.Y.1
Gratacos, E.2
Carrasco, P.3
-
80
-
-
79959335755
-
Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding
-
Gao S, Zhu G, Gao X, et al. Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding. Proc Natl Acad Sci USA 2011;108(23):9691-6
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.23
, pp. 9691-9696
-
-
Gao, S.1
Zhu, G.2
Gao, X.3
-
81
-
-
70349200763
-
Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents
-
Benoit SC, Kemp CJ, Elias CF, et al. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. J Clin Invest 2009;119(9):2577-89
-
(2009)
J Clin Invest
, vol.119
, Issue.9
, pp. 2577-2589
-
-
Benoit, S.C.1
Kemp, C.J.2
Elias, C.F.3
-
82
-
-
58849149821
-
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity
-
Milanski M, Degasperi G, Coope A, et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity. J Neurosci 2009;29(2):359-70
-
(2009)
J Neurosci
, vol.29
, Issue.2
, pp. 359-370
-
-
Milanski, M.1
Degasperi, G.2
Coope, A.3
-
83
-
-
37649003524
-
Regulation of hypothalamic malonyl-CoA by central glucose and leptin
-
Wolfgang MJ, Cha SH, Sidhaye A, et al. Regulation of hypothalamic malonyl-CoA by central glucose and leptin. Proc Natl Acad Sci USA 2007;104(49):19285-90
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.49
, pp. 19285-19290
-
-
Wolfgang, M.J.1
Cha, S.H.2
Sidhaye, A.3
-
84
-
-
22244459572
-
Monitoring energy balance: Metabolites of fatty acid synthesis as hypothalamic sensors
-
Dowell P, Hu Z, Lane MD. Monitoring energy balance: metabolites of fatty acid synthesis as hypothalamic sensors. Annu Rev Biochem 2005;74:515-34
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 515-534
-
-
Dowell, P.1
Hu, Z.2
Lane, M.D.3
-
85
-
-
34447128136
-
Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults
-
Escartin C, Pierre K, Colin A, et al. Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults. J Neurosci 2007;27(27):7094-104
-
(2007)
J Neurosci
, vol.27
, Issue.27
, pp. 7094-7104
-
-
Escartin, C.1
Pierre, K.2
Colin, A.3
-
86
-
-
0023124355
-
Intrahypothalamic injection of insulin decreases firing rate of sympathetic nerves
-
Sakaguchi T, Bray GA. Intrahypothalamic injection of insulin decreases firing rate of sympathetic nerves. Proc Natl Acad Sci USA 1987;84(7):2012-14
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.7
, pp. 2012-2014
-
-
Sakaguchi, T.1
Bray, G.A.2
-
87
-
-
14544279805
-
Longevity, lipotoxicity and leptin: The adipocyte defense against feasting and famine
-
Unger RH. Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine. Biochimie 2005;87(1):57-64
-
(2005)
Biochimie
, vol.87
, Issue.1
, pp. 57-64
-
-
Unger, R.H.1
-
88
-
-
84864396455
-
Roles of ceramide and sphingolipids in pancreatic beta-cell function and dysfunction
-
Boslem E, Meikle PJ, Biden TJ. Roles of ceramide and sphingolipids in pancreatic beta-cell function and dysfunction. Islets 2012;4(3):177-87
-
(2012)
Islets
, vol.4
, Issue.3
, pp. 177-187
-
-
Boslem, E.1
Meikle, P.J.2
Biden, T.J.3
-
89
-
-
64549104642
-
High-fat diet induces apoptosis of hypothalamic neurons
-
Moraes JC, Coope A, Morari J, et al. High-fat diet induces apoptosis of hypothalamic neurons. PLoS One 2009;4(4):e5045
-
(2009)
PLoS One
, vol.4
, Issue.4
-
-
Moraes, J.C.1
Coope, A.2
Morari, J.3
|