메뉴 건너뛰기




Volumn 103, Issue 3, 1999, Pages 413-419

Lipid infusion lowers sympathetic nervous activity and leads to increased β-cell responsiveness to glucose

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA ADRENERGIC RECEPTOR; GLUCOSE; INSULIN; INTRALIPID; ISOPRENALINE; LIPID; OXYMETAZOLINE; PROPRANOLOL DERIVATIVE; TRIACYLGLYCEROL;

EID: 0032960430     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI3883     Document Type: Article
Times cited : (100)

References (39)
  • 1
    • 0030025673 scopus 로고    scopus 로고
    • Hypertension and associated metabolic abnormalities the role of insulin resistance and the sympachoadrenal system
    • Reaven, G., Lithell, H., and Landsberg, L. 1996. Hypertension and associated metabolic abnormalities the role of insulin resistance and the sympachoadrenal system. N. Engl. J. Med. 334:374-381.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 374-381
    • Reaven, G.1    Lithell, H.2    Landsberg, L.3
  • 2
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications
    • Unger, R. 1995. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. Diabetes. 44:863-870.
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.1
  • 3
    • 0024995157 scopus 로고
    • 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation
    • Sako, Y., and Grill, V.A. 1990. 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology. 127:1580-1589.
    • (1990) Endocrinology , vol.127 , pp. 1580-1589
    • Sako, Y.1    Grill, V.A.2
  • 4
    • 0030823179 scopus 로고    scopus 로고
    • Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (bHC9)
    • Liang, X., Buettger, C., Berner, D., and Matchinsky, F. 1997. Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (bHC9). Diabetologia. 40:1018-1027.
    • (1997) Diabetologia , vol.40 , pp. 1018-1027
    • Liang, X.1    Buettger, C.2    Berner, D.3    Matchinsky, F.4
  • 5
    • 15444348663 scopus 로고    scopus 로고
    • Impaired β-cell function and deposition of fat droplets in the pancreas as a consequence of hypertriglycendemia in OLETF rat, a model of spontaneous NIHDM
    • Man, Z., et al. 1997. Impaired β-cell function and deposition of fat droplets in the pancreas as a consequence of hypertriglycendemia in OLETF rat, a model of spontaneous NIHDM Diabetes. 46:1718-1724.
    • (1997) Diabetes , vol.46 , pp. 1718-1724
    • Man, Z.1
  • 6
    • 0029046673 scopus 로고
    • Effects of 48h fat infusion on insulin secretion and glucose utilization
    • Boden, G., Chen, X., Rosner, J., and Barton, M. 1995. Effects of 48h fat infusion on insulin secretion and glucose utilization. Diabetes. 44:1239-1242.
    • (1995) Diabetes , vol.44 , pp. 1239-1242
    • Boden, G.1    Chen, X.2    Rosner, J.3    Barton, M.4
  • 7
    • 0029665527 scopus 로고    scopus 로고
    • High-fat hypercaloric diet induces obesity, glucose intolerance and hyperlipidemia in normal adult male Wistar rat
    • Akiyama, T., Tachibana, I., Shirohara, H., Watanabe, N., and Otsuki, M. 1996. High-fat hypercaloric diet induces obesity, glucose intolerance and hyperlipidemia in normal adult male Wistar rat. Diabetes Res. Clin. Pract. 31:27-35.
    • (1996) Diabetes Res. Clin. Pract. , vol.31 , pp. 27-35
    • Akiyama, T.1    Tachibana, I.2    Shirohara, H.3    Watanabe, N.4    Otsuki, M.5
  • 8
    • 0022869282 scopus 로고
    • Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion
    • Ahren, B., Taborsky, G., and Porte, D. 1986. Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion. Diabetologia. 29:827-836.
    • (1986) Diabetologia , vol.29 , pp. 827-836
    • Ahren, B.1    Taborsky, G.2    Porte, D.3
  • 9
    • 0023912682 scopus 로고
    • Body fat and the activity of the autonomic nervous system
    • Peterson, H., et al. 1988. Body fat and the activity of the autonomic nervous system. N. Engl. Med. 318:1077-1083.
    • (1988) N. Engl. Med. , vol.318 , pp. 1077-1083
    • Peterson, H.1
  • 10
    • 0025845873 scopus 로고
    • Relation of obesity and diet to sympathetic nervous system activity
    • Troisi, R., et al. 1991. Relation of obesity and diet to sympathetic nervous system activity. Hypertension. 5:669-677.
    • (1991) Hypertension , vol.5 , pp. 669-677
    • Troisi, R.1
  • 12
    • 0020826161 scopus 로고
    • Relationship between sympathetic activity and diet-induced obesity in two rat strains
    • Levin, B., Triscari, J., and Sullivan, A. 1983. Relationship between sympathetic activity and diet-induced obesity in two rat strains. Am. J. Physiol. 245:R367-R371.
    • (1983) Am. J. Physiol. , vol.245
    • Levin, B.1    Triscari, J.2    Sullivan, A.3
  • 13
    • 0028013286 scopus 로고
    • Differential effects of dietary fats on sympathetic nervous system activity in the rat
    • Young, J., and Walgren, M. 1994. Differential effects of dietary fats on sympathetic nervous system activity in the rat. Metabolism. 43:51-60.
    • (1994) Metabolism , vol.43 , pp. 51-60
    • Young, J.1    Walgren, M.2
  • 14
    • 0028985060 scopus 로고
    • Pancreatic β-cells in obesity: Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids
    • Milbum, J., et al. 1995. Pancreatic β-cells in obesity: evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. J Biol. Chem. 270:1295-1299.
    • (1995) J Biol. Chem. , vol.270 , pp. 1295-1299
    • Milbum, J.1
  • 15
    • 0019843433 scopus 로고
    • Hyperglycaemia induced by glucose infusion in the unrestrained pregnant rat during the last three days of gestation: Metabolic and hormonal changes in the mother and fetuses
    • Ktorza, A., Girard, J., Kinebanyan, M.F., and Picon, L. 1981. Hyperglycaemia induced by glucose infusion in the unrestrained pregnant rat during the last three days of gestation: metabolic and hormonal changes in the mother and fetuses. Diabetologia. 21:569-574.
    • (1981) Diabetologia , vol.21 , pp. 569-574
    • Ktorza, A.1    Girard, J.2    Kinebanyan, M.F.3    Picon, L.4
  • 16
    • 85038199940 scopus 로고
    • In vivo insulin secretion and action in hyperglycemic rat
    • Laury, M., et al. 1989. In vivo insulin secretion and action in hyperglycemic rat. Am. J. Physiol. 257:E180-E184.
    • (1989) Am. J. Physiol. , vol.257
    • Laury, M.1
  • 17
    • 0028147826 scopus 로고
    • Involvement of theautonomic nervous system in the in vivo memory to glucose of pancreatic β cell in rats
    • Nguyen, J., et al. 1994. Involvement of theautonomic nervous system in the in vivo memory to glucose of pancreatic β cell in rats. J. Clin. Invest. 94:1456-1462.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1456-1462
    • Nguyen, J.1
  • 18
    • 0018850985 scopus 로고
    • A rapid and sensitive DNA assay procedure
    • Labarca, C., and Paigen, K. 1980. A rapid and sensitive DNA assay procedure. Anal. Biochem. 102:344-352.
    • (1980) Anal. Biochem. , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 19
    • 0028268936 scopus 로고
    • Long term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • Zhou, Y., and Grill, V. 1994. Long term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J. Clin. Invest 93:870-876.
    • (1994) J. Clin. Invest , vol.93 , pp. 870-876
    • Zhou, Y.1    Grill, V.2
  • 20
    • 0028988135 scopus 로고
    • Palmitate-induced β-cell insensitivity to glucose is coupled to decreased pyruvate dehydrogenase activity and enhanced kinase activity in rat pancreatic islets
    • Zhou, Y., and Grill, V. 1995. Palmitate-induced β-cell insensitivity to glucose is coupled to decreased pyruvate dehydrogenase activity and enhanced kinase activity in rat pancreatic islets. Diabetes. 44:394-399
    • (1995) Diabetes , vol.44 , pp. 394-399
    • Zhou, Y.1    Grill, V.2
  • 21
    • 0031019883 scopus 로고    scopus 로고
    • Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic β-cell line INS-1
    • Assimacopoulos-Jeannet, F., et al. 1997. Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic β-cell line INS-1. J. Biol. Chem. 272:1659-1664.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1659-1664
    • Assimacopoulos-Jeannet, F.1
  • 22
    • 0030731946 scopus 로고    scopus 로고
    • Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels
    • Gremlich, S., Bonny, C., Waeber, G., and Thorens, B. 1997. Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels. J. Biol Chem. 272:30261-30269.
    • (1997) J. Biol Chem. , vol.272 , pp. 30261-30269
    • Gremlich, S.1    Bonny, C.2    Waeber, G.3    Thorens, B.4
  • 23
    • 0028221978 scopus 로고
    • Mechanisms of the stimulation of insulin release by saturated fatty acids
    • Warnotte, C., Gilon, P., Nenquin, M., and Henquin, J. 1994. Mechanisms of the stimulation of insulin release by saturated fatty acids. Diabetes. 43:703-711.
    • (1994) Diabetes , vol.43 , pp. 703-711
    • Warnotte, C.1    Gilon, P.2    Nenquin, M.3    Henquin, J.4
  • 24
    • 0030950231 scopus 로고    scopus 로고
    • Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids
    • Hosokawa, H., Corkey, B., and Leahy, J. 1997. Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids. Diabetologia. 40:392-397.
    • (1997) Diabetologia , vol.40 , pp. 392-397
    • Hosokawa, H.1    Corkey, B.2    Leahy, J.3
  • 25
    • 0032030866 scopus 로고    scopus 로고
    • Chronic exposure to free fatty acid reduces pancreatic β cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation
    • Bollheimer, L., Skelly, R., Chester, M., McGarry, J., and Rhodes, C. 1998. Chronic exposure to free fatty acid reduces pancreatic β cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J. Clin. Invest. 101:1094-1101.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1094-1101
    • Bollheimer, L.1    Skelly, R.2    Chester, M.3    McGarry, J.4    Rhodes, C.5
  • 26
    • 0026733643 scopus 로고
    • Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion
    • Prentki, M., et al. 1992. Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. J. Biol. Chem. 267:5802-5810.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5802-5810
    • Prentki, M.1
  • 27
    • 0027184924 scopus 로고
    • Differential effects of hyperinsulinemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans
    • Vollenweider, P.,et al. 1993 Differential effects of hyperinsulinemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans. J. Clin. Invest. 92:147-154.
    • (1993) J. Clin. Invest. , vol.92 , pp. 147-154
    • Vollenweider, P.1
  • 28
    • 0026034609 scopus 로고
    • Metabolic and neurologic effects of an intravenous medium-chain tnglycende emulsion
    • Miles, J., et al. 1991. Metabolic and neurologic effects of an intravenous medium-chain tnglycende emulsion. J. Parenter. Enteral. Nutr. 15:37-41.
    • (1991) J. Parenter. Enteral. Nutr. , vol.15 , pp. 37-41
    • Miles, J.1
  • 29
    • 0025005549 scopus 로고
    • Involvement of alpha2-adrenoreceptor subtypes in hyperglycemia
    • Angel, I., Niddam, R.. and Langer, S. 1990. Involvement of alpha2-adrenoreceptor subtypes in hyperglycemia. J. Pharmacol. Exp. Ther. 254:877-882.
    • (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 877-882
    • Angel, I.1    Niddam, R.2    Langer, S.3
  • 30
    • 0023268029 scopus 로고
    • The determination of alpha-adrenergic receptor concentration on rat pancreatic islet cells
    • Fyles, J., Cawthorne, M., and Howell, S. 1987. The determination of alpha-adrenergic receptor concentration on rat pancreatic islet cells. Biosci. Rep. 7:17-22.
    • (1987) Biosci. Rep. , vol.7 , pp. 17-22
    • Fyles, J.1    Cawthorne, M.2    Howell, S.3
  • 31
    • 0022527589 scopus 로고
    • The charactensticsofbeta-adrcnergic binding sites on pancreatic islets of Langerhans
    • Fyles, J., Cawthorne, M., and Howell, S. 1986. The charactensticsofbeta-adrcnergic binding sites on pancreatic islets of Langerhans. J. Endocrinol. 111:263-270.
    • (1986) J. Endocrinol. , vol.111 , pp. 263-270
    • Fyles, J.1    Cawthorne, M.2    Howell, S.3
  • 33
    • 0028430876 scopus 로고
    • Arterial α-adrenergic responsiveness is decreased and SNS activity is increased in older humans
    • Hogikyan, R., and Supiano, M. 1995. Arterial α-adrenergic responsiveness is decreased and SNS activity is increased in older humans. Am. J. Physiol. 266.E717-E724.
    • (1995) Am. J. Physiol. , vol.266
    • Hogikyan, R.1    Supiano, M.2
  • 34
    • 0028893619 scopus 로고
    • Canine myocardial beta adrenergic, muscarinic receptor densities after denervation: A PET study
    • Valette, H., et al. 1995. Canine myocardial beta adrenergic, muscarinic receptor densities after denervation: a PET study. J. Nucl. Med. 36:140-146.
    • (1995) J. Nucl. Med. , vol.36 , pp. 140-146
    • Valette, H.1
  • 35
    • 0026874525 scopus 로고
    • Up-regulation of beta-adrenoceptor on circulating mononuclear cells after reduction of central sympathetic outflow by clonidine in normal subjects
    • Zoukos, Y., et al. 1992. Up-regulation of beta-adrenoceptor on circulating mononuclear cells after reduction of central sympathetic outflow by clonidine in normal subjects. Acta Neurol Scand. 2:165-170.
    • (1992) Acta Neurol Scand. , vol.2 , pp. 165-170
    • Zoukos, Y.1
  • 36
    • 0025897054 scopus 로고
    • Comparison of DNA contents of visceral organs in rats with ventromedial hypothalamic lesions and fed high fat diet
    • Kiba, T., Tanaka, K., Inoue, S., Endo, O., and Takamura, Y. 1991. Comparison of DNA contents of visceral organs in rats with ventromedial hypothalamic lesions and fed high fat diet. Neurosci. Lett. 126:127-130.
    • (1991) Neurosci. Lett. , vol.126 , pp. 127-130
    • Kiba, T.1    Tanaka, K.2    Inoue, S.3    Endo, O.4    Takamura, Y.5
  • 37
    • 0026341637 scopus 로고
    • Fatty acids in the portal vein of the rat regulate hepatic insulin clearance
    • Svedberg, J., Strömblad, G., Wirth, A., Smith, U., and Björntorp, P. 1991. Fatty acids in the portal vein of the rat regulate hepatic insulin clearance. J. Clin. Invest. 88:2054-2058.
    • (1991) J. Clin. Invest. , vol.88 , pp. 2054-2058
    • Svedberg, J.1    Strömblad, G.2    Wirth, A.3    Smith, U.4    Björntorp, P.5
  • 38
    • 0025182175 scopus 로고
    • Beta cell hyperresponsiveness: Earliest event in development of diabetes in monkeys
    • Hansen, B., and Bodkin, N. 1990 Beta cell hyperresponsiveness: earliest event in development of diabetes in monkeys. Am. J. Physiol. 259:R612-R617.
    • (1990) Am. J. Physiol. , vol.259
    • Hansen, B.1    Bodkin, N.2
  • 39
    • 0002250213 scopus 로고
    • Diabetes in animals
    • H. Rifkin and D.I. Porte, editors. Elsevier Science. New York, NY
    • Shafrir, E. 1990. Diabetes in animals. In Diabetes mellitus: theory and practice IV. H. Rifkin and D.I. Porte, editors. Elsevier Science. New York, NY. 299-340.
    • (1990) Diabetes Mellitus: Theory and Practice IV , pp. 299-340
    • Shafrir, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.