Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

Neurochemistry International

Volumn 62, Issue 5, 2013, Pages 764-775

  Smith, Joshua A ^a   Park, Sookyoung ^a   Krause, James S ^b   Banik, Naren L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

CNS injury; DNA damage; Neuron death; Oxidative stress; Telomerase; Telomere

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; COMPLEMENTARY DNA; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE; GUANINE; KU ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PEROXYNITRITE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROGESTERONE; RNA POLYMERASE II; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; XRCC4 PROTEIN;

ACUTE DISEASE; APURINIC SITE; ATAXIA TELANGIECTASIA; BRAIN INJURY; BRAIN ISCHEMIA; CELL DAMAGE; CEREBELLUM CORTEX; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DNA STRUCTURE; DYSKERATOSIS; GRAFT REJECTION; HUMAN; LOSS OF FUNCTION MUTATION; MAMMAL CELL; MENTAL DEFICIENCY; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NERVE DEGENERATION; NEUROBLASTOMA CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PHASE 3 CLINICAL TRIAL (TOPIC); PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; REPERFUSION INJURY; REVIEW; SPEECH DISORDER; SPINAL CORD INJURY; TELOMERE; TRAUMATIC BRAIN INJURY; XERODERMA PIGMENTOSUM;

ANIMALS; DNA DAMAGE; HUMANS; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; TELOMERE;

EID: 84875725411     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.02.013     Document Type: Review

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