Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria

Journal of Neurochemistry

Volumn 81, Issue 6, 2002, Pages 1273-1284

  Chen, Dexi ^a   Cao, Guodong ^a   Hastings, Teresa ^a   Feng, Yiqin ^a   Pei, Wei ^a   O'Horo, Cristine ^a   Chen, Jun ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

8 hydroxyl 2 deoxyguanosine; Aging; DNA damage; Mitochondrial dysfunction; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYDEOXYGUANOSINE GLYCOSYLASE; CELL PROTEIN; DNA DIRECTED DNA POLYMERASE GAMMA; DNA GLYCOSYLTRANSFERASE; MITOCHONDRIAL DNA; UNCLASSIFIED DRUG;

AGE; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN MITOCHONDRION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA DAMAGE; DNA REPAIR; DNA SYNTHESIS; DOSE TIME EFFECT RELATION; EMBRYO; ENZYME ASSAY; EXCISION REPAIR; EXTRACT; FETUS; NEWBORN; NONHUMAN; OXIDATION KINETICS; OXIDATIVE STRESS; PATHOGENESIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AGING; ANIMALS; BASE SEQUENCE; BRAIN; DNA LIGASES; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; N-GLYCOSYL HYDROLASES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; ZIZIPHUS MAURITIANA;

EID: 0036316413     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00916.x     Document Type: Article

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