Attenuation of DNA polymerase β-dependent base excision repair and increased DMS-induced mutagenicity in aged mice

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 500, Issue 1-2, 2002, Pages 135-145

  Cabelof, Diane C ^a   Raffoul, Julian J ^a   Yanamadala, Sunitha ^a   Ganir, Cirlette ^a   Guo, ZhongMao ^b   Heydari, Ahmad R ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Aging; Base excision repair; Dimethyl sulfate; DNA polymerase ; Mutation frequency

Indexed keywords

DIMETHYL SULFATE; DNA DIRECTED DNA POLYMERASE BETA; MESSENGER RNA; PROTEIN;

AGE; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; ENZYME ACTIVITY; EXCISION REPAIR; GENE FREQUENCY; IN VITRO STUDY; LIVER; MALE; MOUSE; MUTAGENICITY; MUTATION RATE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN; TESTIS;

ANIMALIA; ZIZIPHUS MAURITIANA;

EID: 0037139232     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(02)00003-9     Document Type: Article

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