Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity

Journal of Neuroscience

Volumn 24, Issue 6, 2004, Pages 1280-1287

  Kang, Hyo Jung ^a   Choi, Yoon Sik ^b   Hong, Seung Beom ^b   Kim, Kee Won ^c   Woo, Ran Sook ^c   Won, Seok Joon ^a   Kim, Eun Ju ^b   Jeon, Hee Kyung ^b   Jo, So Young ^b   Kim, Tae Kook ^d   Bachoo, Robert ^e   Reynolds, Ian J ^f   Gwag, Byoung Joo ^a   Lee, Han Woong ^b  

^a Ajou University School of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Chonbuk National University Medical School   (South Korea)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^e HARVARD MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium; Catalytic subunit of telomerase; Excitotoxicity; Ischemia; Mitochondria; NMDA

Indexed keywords

CALCIUM ION; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN INJURY; CALCIUM CELL LEVEL; CATALYSIS; CELL DEATH; CELL DIVISION; CELL MEMBRANE; CELL PROTECTION; CONTROLLED STUDY; ENZYME SUBUNIT; EXCITOTOXICITY; FOREBRAIN; GENE OVEREXPRESSION; IN VITRO STUDY; ISCHEMIA; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRIAL RESPIRATION; MITOSIS; MOUSE; NERVE CELL NECROSIS; NERVE EXCITABILITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; SENESCENCE; TRANSGENIC MOUSE;

ANIMALS; BRAIN INJURY, CHRONIC; BRAIN ISCHEMIA; CALCIUM; CELLS, CULTURED; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; EXCITATORY AMINO ACID AGONISTS; FLUORESCENT DYES; GENE EXPRESSION REGULATION; HYPOXIA-ISCHEMIA, BRAIN; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; N-METHYLASPARTATE; NEUROGLIA; NEURONS; NEUROTOXICITY SYNDROMES; NEUROTOXINS; RNA, MESSENGER; TELOMERASE;

EID: 10744219690     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4082-03.2004     Document Type: Article

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