Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: Effect of dosing, route of administration, and therapy delay

Neurochemical Research

Volumn 36, Issue 10, 2011, Pages 1809-1816

  Samantaray, Supriti ^a   Smith, Joshua A ^a   Das, Arabinda ^a   Matzelle, Denise D ^a   Varma, Abhay K ^a   Ray, Swapan K ^b   Banik, Naren L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Estrogen; Microgliosis; Neurodegeneration; Spinal cord injury

Indexed keywords

ESTRADIOL; ESTROGEN; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CELL ACTIVATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ESTROGEN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LOW DRUG DOSE; MALE; MICROGLIA; MICROGLIOSIS; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROLOGIC DISEASE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; THERAPY DELAY; WESTERN BLOTTING;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CELL DEATH; ESTRADIOL; ESTROGENS; INFLAMMATION; MALE; METHYLPREDNISOLONE; MICROGLIA; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD INJURIES;

RATTUS;

EID: 80555150797     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0498-y     Document Type: Article

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