-
1
-
-
33745606159
-
Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release
-
Ahmad-Annuar A., Ciani L., Simeonidis I., Herreros J., Fredj N.B., Rosso S.B., Hall A., Brickley S., Salinas P.C. Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release. J. Cell. Biol. 2006, 174:127-139.
-
(2006)
J. Cell. Biol.
, vol.174
, pp. 127-139
-
-
Ahmad-Annuar, A.1
Ciani, L.2
Simeonidis, I.3
Herreros, J.4
Fredj, N.B.5
Rosso, S.B.6
Hall, A.7
Brickley, S.8
Salinas, P.C.9
-
2
-
-
2942578107
-
Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons
-
Alvarez A.R., Godoy J.A., Mullendorff K., Olivares G.H., Bronfman M., Inestrosa N.C. Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons. Exp. Cell. Res. 2004, 297:186-196.
-
(2004)
Exp. Cell. Res.
, vol.297
, pp. 186-196
-
-
Alvarez, A.R.1
Godoy, J.A.2
Mullendorff, K.3
Olivares, G.H.4
Bronfman, M.5
Inestrosa, N.C.6
-
3
-
-
0036276050
-
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
-
Alvarez G., Muñoz-Montaño J.R., Satrústegui J., Avila J., Bogónez E., Díaz-Nido J. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord. 2002, 4:153-165.
-
(2002)
Bipolar Disord.
, vol.4
, pp. 153-165
-
-
Alvarez, G.1
Muñoz-Montaño, J.R.2
Satrústegui, J.3
Avila, J.4
Bogónez, E.5
Díaz-Nido, J.6
-
4
-
-
3442876969
-
Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets
-
Andersen C.L., Jensen J.L., Ørntoft T.F. Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res. 2004, 64:5245-5250.
-
(2004)
Cancer Res.
, vol.64
, pp. 5245-5250
-
-
Andersen, C.L.1
Jensen, J.L.2
Ørntoft, T.F.3
-
5
-
-
77953295258
-
Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons
-
Avila M.E., Sepúlveda F.J., Burgos C.F., Moraga-Cid G., Parodi J., Moon R.T., Aguayo L.G., Opazo C., De Ferrari G.V. Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons. J. Biol. Chem. 2010, 285:18939-18947.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 18939-18947
-
-
Avila, M.E.1
Sepúlveda, F.J.2
Burgos, C.F.3
Moraga-Cid, G.4
Parodi, J.5
Moon, R.T.6
Aguayo, L.G.7
Opazo, C.8
De Ferrari, G.V.9
-
6
-
-
34547612803
-
Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation
-
Beaumont V., Thompson S.A., Choudhry F., Nuthall H., Glantschnig H., Lipfert L., David G.R., Swain C.J., McAllister G., Munoz-Sanjuan I. Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation. Mol. Cell. Neurosci. 2007, 35:513-524.
-
(2007)
Mol. Cell. Neurosci.
, vol.35
, pp. 513-524
-
-
Beaumont, V.1
Thompson, S.A.2
Choudhry, F.3
Nuthall, H.4
Glantschnig, H.5
Lipfert, L.6
David, G.R.7
Swain, C.J.8
McAllister, G.9
Munoz-Sanjuan, I.10
-
7
-
-
1642334902
-
Genetic variation in CTNNA3 encoding alpha-3 catenin and Alzheimer's disease
-
Blomqvist M.E., Andreasen N., Bogdanovic N., Blennow K., Brookes A.J., Prince J.A. Genetic variation in CTNNA3 encoding alpha-3 catenin and Alzheimer's disease. Neurosci. Lett. 2004, 358:220-222.
-
(2004)
Neurosci. Lett.
, vol.358
, pp. 220-222
-
-
Blomqvist, M.E.1
Andreasen, N.2
Bogdanovic, N.3
Blennow, K.4
Brookes, A.J.5
Prince, J.A.6
-
8
-
-
0036338127
-
Alternative splicing and genome complexity
-
Brett D., Pospisil H., Valcárcel J., Reich J., Bork P. Alternative splicing and genome complexity. Nat. Genet. 2002, 30:29-30.
-
(2002)
Nat. Genet.
, vol.30
, pp. 29-30
-
-
Brett, D.1
Pospisil, H.2
Valcárcel, J.3
Reich, J.4
Bork, P.5
-
9
-
-
2342574965
-
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease
-
Busby V., Goossens S., Nowotny P., Hamilton G., Smemo S., Harold D., Turic D., Jehu L., Myers A., Womick M., Woo D., Compton D., Doil L.M., Tacey K.M., Lau K.F., Al-Saraj S., Killick R., Pickering-Brown S., Moore P., Hollingworth P., Archer N., Foy C., Walter S., Lendon C., Iwatsubo T., Morris J.C., Norton J., Mann D., Janssens B., Hardy J., O'Donovan M., Jones L., Williams J., Holmans P., Owen M.J., Grupe A., Powell J., van Hengel J., Goate A., Van Roy F., Lovestone S. Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. Neuromolecular Med. 2004, 5:133-146.
-
(2004)
Neuromolecular Med.
, vol.5
, pp. 133-146
-
-
Busby, V.1
Goossens, S.2
Nowotny, P.3
Hamilton, G.4
Smemo, S.5
Harold, D.6
Turic, D.7
Jehu, L.8
Myers, A.9
Womick, M.10
Woo, D.11
Compton, D.12
Doil, L.M.13
Tacey, K.M.14
Lau, K.F.15
Al-Saraj, S.16
Killick, R.17
Pickering-Brown, S.18
Moore, P.19
Hollingworth, P.20
Archer, N.21
Foy, C.22
Walter, S.23
Lendon, C.24
Iwatsubo, T.25
Morris, J.C.26
Norton, J.27
Mann, D.28
Janssens, B.29
Hardy, J.30
O'Donovan, M.31
Jones, L.32
Williams, J.33
Holmans, P.34
Owen, M.J.35
Grupe, A.36
Powell, J.37
van Hengel, J.38
Goate, A.39
Van Roy, F.40
Lovestone, S.41
more..
-
10
-
-
64149097786
-
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
-
Bustin S.A., Benes V., Garson J.A., Hellemans J., Huggett J., Kubista M., Mueller R., Nolan T., Pfaffl M.W., Shipley G.L., Vandesompele J., Wittwer C.T. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 2009, 55:611-622.
-
(2009)
Clin. Chem.
, vol.55
, pp. 611-622
-
-
Bustin, S.A.1
Benes, V.2
Garson, J.A.3
Hellemans, J.4
Huggett, J.5
Kubista, M.6
Mueller, R.7
Nolan, T.8
Pfaffl, M.W.9
Shipley, G.L.10
Vandesompele, J.11
Wittwer, C.T.12
-
11
-
-
0036534129
-
Alternative splicing: multiple control mechanisms and involvement in human disease
-
Caceres J.F., Kornblihtt A.R. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet. 2002, 18:186-193.
-
(2002)
Trends Genet.
, vol.18
, pp. 186-193
-
-
Caceres, J.F.1
Kornblihtt, A.R.2
-
12
-
-
3042834662
-
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain
-
Caricasole A., Copani A., Caraci F., Aronica E., Rozemuller A.J., Caruso A., Storto M., Gaviraghi G., Terstappen G.C., Nicoletti F. Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain. J. Neurosci. 2004, 24:6021-6027.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6021-6027
-
-
Caricasole, A.1
Copani, A.2
Caraci, F.3
Aronica, E.4
Rozemuller, A.J.5
Caruso, A.6
Storto, M.7
Gaviraghi, G.8
Terstappen, G.C.9
Nicoletti, F.10
-
13
-
-
0037723974
-
The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease?
-
Caricasole A., Copani A., Caruso A., Caraci F., Iacovelli L., Sortino M.A., Terstappen G.C., Nicoletti F. The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease?. Trends Pharmacol. Sci. 2003, 24:233-238.
-
(2003)
Trends Pharmacol. Sci.
, vol.24
, pp. 233-238
-
-
Caricasole, A.1
Copani, A.2
Caruso, A.3
Caraci, F.4
Iacovelli, L.5
Sortino, M.A.6
Terstappen, G.C.7
Nicoletti, F.8
-
14
-
-
33746543634
-
Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells
-
Caruso A., Motolese M., Iacovelli L., Caraci F., Copani A., Nicoletti F., Terstappen G.C., Gaviraghi G., Caricasole A. Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells. J. Neurochem. 2006, 98:364-371.
-
(2006)
J. Neurochem.
, vol.98
, pp. 364-371
-
-
Caruso, A.1
Motolese, M.2
Iacovelli, L.3
Caraci, F.4
Copani, A.5
Nicoletti, F.6
Terstappen, G.C.7
Gaviraghi, G.8
Caricasole, A.9
-
15
-
-
41949142202
-
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons
-
Cerpa W., Godoy J.A., Alfaro I., Farías G.G., Metcalfe M.J., Fuentealba R., Bonansco C., Inestrosa N.C. Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons. J. Biol. Chem. 2008, 283:5918-5927.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5918-5927
-
-
Cerpa, W.1
Godoy, J.A.2
Alfaro, I.3
Farías, G.G.4
Metcalfe, M.J.5
Fuentealba, R.6
Bonansco, C.7
Inestrosa, N.C.8
-
16
-
-
33744958556
-
Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation
-
Chen J., Park C.S., Tang S.J. Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation. J. Biol. Chem. 2006, 281:11910-11916.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11910-11916
-
-
Chen, J.1
Park, C.S.2
Tang, S.J.3
-
17
-
-
79751481634
-
MAPT isoforms: differential transcriptional profiles related to 3R and 4R splice variants
-
Chen S., Townsend K., Goldberg T.E., Davies P., Conejero-Goldberg C. MAPT isoforms: differential transcriptional profiles related to 3R and 4R splice variants. J. Alzheimers Dis. 2010, 22:1313-1329.
-
(2010)
J. Alzheimers Dis.
, vol.22
, pp. 1313-1329
-
-
Chen, S.1
Townsend, K.2
Goldberg, T.E.3
Davies, P.4
Conejero-Goldberg, C.5
-
18
-
-
0034566385
-
Quantitative evaluation of the rRNA in Alzheimer's disease
-
da Silva A., Payão S.L., Borsatto B., Bertolucci P.H., Smith M.A. Quantitative evaluation of the rRNA in Alzheimer's disease. Mech. Ageing Dev. 2000, 120:57-64.
-
(2000)
Mech. Ageing Dev.
, vol.120
, pp. 57-64
-
-
da Silva, A.1
Payão, S.L.2
Borsatto, B.3
Bertolucci, P.H.4
Smith, M.A.5
-
19
-
-
0037220599
-
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
-
De Ferrari G.V., Chacón M.A., Barría M.I., Garrido J.L., Godoy J.A., Olivares G., Reyes A.E., Alvarez A., Bronfman M., Inestrosa N.C. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol. Psychiatry 2003, 8:195-208.
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 195-208
-
-
De Ferrari, G.V.1
Chacón, M.A.2
Barría, M.I.3
Garrido, J.L.4
Godoy, J.A.5
Olivares, G.6
Reyes, A.E.7
Alvarez, A.8
Bronfman, M.9
Inestrosa, N.C.10
-
21
-
-
33845350346
-
The ups and downs of Wnt signaling in prevalent neurological disorders
-
De Ferrari G.V., Moon R.T. The ups and downs of Wnt signaling in prevalent neurological disorders. Oncogene 2006, 25:7545-7553.
-
(2006)
Oncogene
, vol.25
, pp. 7545-7553
-
-
De Ferrari, G.V.1
Moon, R.T.2
-
22
-
-
34547191230
-
Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease
-
De Ferrari G.V., Papassotiropoulos A., Biechele T., Wavrant De-Vrieze F., Avila M.E., Major M.B., Myers A., Sáez K., Henríquez J.P., Zhao A., Wollmer M.A., Nitsch R.M., Hock C., Morris C.M., Hardy J., Moon R.T. Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:9434-9439.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 9434-9439
-
-
De Ferrari, G.V.1
Papassotiropoulos, A.2
Biechele, T.3
Wavrant De-Vrieze, F.4
Avila, M.E.5
Major, M.B.6
Myers, A.7
Sáez, K.8
Henríquez, J.P.9
Zhao, A.10
Wollmer, M.A.11
Nitsch, R.M.12
Hock, C.13
Morris, C.M.14
Hardy, J.15
Moon, R.T.16
-
23
-
-
0033581835
-
Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability
-
Duval A., Iacopetta B., Ranzani G.N., Lothe R.A., Thomas G., Hamelin R. Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability. Oncogene 1999, 18:6806-6809.
-
(1999)
Oncogene
, vol.18
, pp. 6806-6809
-
-
Duval, A.1
Iacopetta, B.2
Ranzani, G.N.3
Lothe, R.A.4
Thomas, G.5
Hamelin, R.6
-
24
-
-
0344668728
-
Fine mapping of the alpha-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N., Ronald J., Asahara H., Younkin L., Hella M., Jain S., Gnida E., Younkin S., Fadale D., Ohyagi Y., Singleton A., Scanlin L., de Andrade M., Petersen R., Graff-Radford N., Hutton M., Younkin S. Fine mapping of the alpha-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Hum. Mol. Genet. 2003, 12:3133-3143.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3133-3143
-
-
Ertekin-Taner, N.1
Ronald, J.2
Asahara, H.3
Younkin, L.4
Hella, M.5
Jain, S.6
Gnida, E.7
Younkin, S.8
Fadale, D.9
Ohyagi, Y.10
Singleton, A.11
Scanlin, L.12
de Andrade, M.13
Petersen, R.14
Graff-Radford, N.15
Hutton, M.16
Younkin, S.17
-
25
-
-
0037443035
-
Pre-mRNA splicing and human disease
-
Faustino N.A., Cooper T.A. Pre-mRNA splicing and human disease. Genes Dev. 2003, 17:419-437.
-
(2003)
Genes Dev.
, vol.17
, pp. 419-437
-
-
Faustino, N.A.1
Cooper, T.A.2
-
26
-
-
78049512761
-
Housekeepers for accurate transcript expression analysis in Alzheimer's disease autopsy brain tissue
-
Gebhardt F.M., Scott H.A., Dodd P.R. Housekeepers for accurate transcript expression analysis in Alzheimer's disease autopsy brain tissue. Alzheimers Dement. 2010, 6:465-474.
-
(2010)
Alzheimers Dement.
, vol.6
, pp. 465-474
-
-
Gebhardt, F.M.1
Scott, H.A.2
Dodd, P.R.3
-
27
-
-
72849132718
-
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain
-
Grear K.E., Ling I.F., Simpson J.F., Furman J.L., Simmons C.R., Peterson S.L., Schmitt F.A., Markesbery W.R., Liu Q., Crook J.E., Younkin S.G., Bu G., Estus S. Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain. Mol. Neurodegener. 2009, 4:46.
-
(2009)
Mol. Neurodegener.
, vol.4
, pp. 46
-
-
Grear, K.E.1
Ling, I.F.2
Simpson, J.F.3
Furman, J.L.4
Simmons, C.R.5
Peterson, S.L.6
Schmitt, F.A.7
Markesbery, W.R.8
Liu, Q.9
Crook, J.E.10
Younkin, S.G.11
Bu, G.12
Estus, S.13
-
28
-
-
0348134529
-
Alzheimer's disease linking neurodegeneration with neurodevelopment
-
Grilli M., Ferrari Toninelli G., Uberti D., Spano P., Memo M. Alzheimer's disease linking neurodegeneration with neurodevelopment. Funct. Neurol. 2003, 18:145-148.
-
(2003)
Funct. Neurol.
, vol.18
, pp. 145-148
-
-
Grilli, M.1
Ferrari Toninelli, G.2
Uberti, D.3
Spano, P.4
Memo, M.5
-
29
-
-
0346995416
-
The use of real-time PCR analysis in a gene expression study of Alzheimer's disease post-mortem brains
-
Gutala R.V., Reddy P.H. The use of real-time PCR analysis in a gene expression study of Alzheimer's disease post-mortem brains. J. Neurosci. Methods 2004, 132:101-107.
-
(2004)
J. Neurosci. Methods
, vol.132
, pp. 101-107
-
-
Gutala, R.V.1
Reddy, P.H.2
-
30
-
-
0026487365
-
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase
-
Hanger D.P., Hughes K., Woodgett J.R., Brion J.P., Anderton B.H. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci. Lett. 1992, 147:58-62.
-
(1992)
Neurosci. Lett.
, vol.147
, pp. 58-62
-
-
Hanger, D.P.1
Hughes, K.2
Woodgett, J.R.3
Brion, J.P.4
Anderton, B.H.5
-
31
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
32
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way
-
He X., Semenov M., Tamai K., Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 2004, 131:1663-1677.
-
(2004)
Development
, vol.131
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
33
-
-
34248559599
-
Gene splicing and mutagenesis by PCR-driven overlap extension
-
Heckman K.L., Pease L.R. Gene splicing and mutagenesis by PCR-driven overlap extension. Nat. Protoc. 2007, 2:924-932.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 924-932
-
-
Heckman, K.L.1
Pease, L.R.2
-
34
-
-
0034123008
-
Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions
-
Hu Q., Jin L.W., Starbuck M.Y., Martin G.M. Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions. J. Neurosci. Res. 2000, 60:73-86.
-
(2000)
J. Neurosci. Res.
, vol.60
, pp. 73-86
-
-
Hu, Q.1
Jin, L.W.2
Starbuck, M.Y.3
Martin, G.M.4
-
35
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
International HapMap Consortium
-
Frazer K.A., Ballinger D.G., Cox D.R., Hinds D.A., Stuve L.L., Gibbs R.A., Belmont J.W., Boudreau A., Hardenbol P., Leal S.M., Pasternak S., Wheeler D.A., Willis T.D., Yu F., Yang H., Zeng C., Gao Y., Hu H., Hu W., Li C., Lin W., Liu S., Pan H., Tang X., Wang J., Wang W., Yu J., Zhang B., Zhang Q., Zhao H., Zhao H., Zhou J., Gabriel S.B., Barry R., Blumenstiel B., Camargo A., Defelice M., Faggart M., Goyette M., Gupta S., Moore J., Nguyen H., Onofrio R.C., Parkin M., Roy J., Stahl E., Winchester E., Ziaugra L., Altshuler D., Shen Y., Yao Z., Huang W., Chu X., He Y., Jin L., Liu Y., Shen Y., Sun W., Wang H., Wang Y., Wang Y., Xiong X., Xu L., Waye M.M., Tsui S.K., Xue H., Wong J.T., Galver L.M., Fan J.B., Gunderson K., Murray S.S., Oliphant A.R., Chee M.S., Montpetit A., Chagnon F., Ferretti V., Leboeuf M., Olivier J.F., Phillips M.S., Roumy S., Sallée C., Verner A., Hudson T.J., Kwok P.Y., Cai D., Koboldt D.C., Miller R.D., Pawlikowska L., Taillon-Miller P., Xiao M., Tsui L.C., Mak W., Song Y.Q., Tam P.K., Nakamura Y., Kawaguchi T., Kitamoto T., Morizono T., Nagashima A., Ohnishi Y., Sekine A., Tanaka T., Tsunoda T., Deloukas P., Bird C.P., Delgado M., Dermitzakis E.T., Gwilliam R., Hunt S., Morrison J., Powell D., Stranger B.E., Whittaker P., Bentley D.R., Daly M.J., de Bakker P.I., Barrett J., Chretien Y.R., Maller J., McCarroll S., Patterson N., Pe'er I., Price A., Purcell S., Richter D.J., Sabeti P., Saxena R., Schaffner S.F., Sham P.C., Varilly P., Altshuler D., Stein L.D., Krishnan L., Smith A.V., Tello-Ruiz M.K., Thorisson G.A., Chakravarti A., Chen P.E., Cutler D.J., Kashuk C.S., Lin S., Abecasis G.R., Guan W., Li Y., Munro H.M., Qin Z.S., Thomas D.J., McVean G., Auton A., Bottolo L., Cardin N., Eyheramendy S., Freeman C., Marchini J., Myers S., Spencer C., Stephens M., Donnelly P., Cardon L.R., Clarke G., Evans D.M., Morris A.P., Weir B.S., Tsunoda T., Mullikin J.C., Sherry S.T., Feolo M., Skol A., Zhang H., Zeng C., Zhao H., Matsuda I., Fukushima Y., Macer D.R., Suda E., Rotimi C.N., Adebamowo C.A., Ajayi I., Aniagwu T., Marshall P.A., Nkwodimmah C., Royal C.D., Leppert M.F., Dixon M., Peiffer A., Qiu R., Kent A., Kato K., Niikawa N., Adewole I.F., Knoppers B.M., Foster M.W., Clayton E.W., Watkin J., Gibbs R.A., Belmont J.W., Muzny D., Nazareth L., Sodergren E., Weinstock G.M., Wheeler D.A., Yakub I., Gabriel S.B., Onofrio R.C., Richter D.J., Ziaugra L., Birren B.W., Daly M.J., Altshuler D., Wilson R.K., Fulton L.L., Rogers J., Burton J., Carter N.P., Clee C.M., Griffiths M., Jones M.C., McLay K., Plumb R.W., Ross M.T., Sims S.K., Willey D.L., Chen Z., Han H., Kang L., Godbout M., Wallenburg J.C., L'Archevêque P., Bellemare G., Saeki K., Wang H., An D., Fu H., Li Q., Wang Z., Wang R., Holden A.L., Brooks L.D., McEwen J.E., Guyer M.S., Wang V.O., Peterson J.L., Shi M., Spiegel J., Sung L.M., Zacharia L.F., Collins F.S., Kennedy K., Jamieson R., Stewart J. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007, 449:851-861. International HapMap Consortium.
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
Frazer, K.A.1
Ballinger, D.G.2
Cox, D.R.3
Hinds, D.A.4
Stuve, L.L.5
Gibbs, R.A.6
Belmont, J.W.7
Boudreau, A.8
Hardenbol, P.9
Leal, S.M.10
Pasternak, S.11
Wheeler, D.A.12
Willis, T.D.13
Yu, F.14
Yang, H.15
Zeng, C.16
Gao, Y.17
Hu, H.18
Hu, W.19
Li, C.20
Lin, W.21
Liu, S.22
Pan, H.23
Tang, X.24
Wang, J.25
Wang, W.26
Yu, J.27
Zhang, B.28
Zhang, Q.29
Zhao, H.30
Zhao, H.31
Zhou, J.32
Gabriel, S.B.33
Barry, R.34
Blumenstiel, B.35
Camargo, A.36
Defelice, M.37
Faggart, M.38
Goyette, M.39
Gupta, S.40
Moore, J.41
Nguyen, H.42
Onofrio, R.C.43
Parkin, M.44
Roy, J.45
Stahl, E.46
Winchester, E.47
Ziaugra, L.48
Altshuler, D.49
Shen, Y.50
Yao, Z.51
Huang, W.52
Chu, X.53
He, Y.54
Jin, L.55
Liu, Y.56
Shen, Y.57
Sun, W.58
Wang, H.59
Wang, Y.60
Wang, Y.61
Xiong, X.62
Xu, L.63
Waye, M.M.64
Tsui, S.K.65
Xue, H.66
Wong, J.T.67
Galver, L.M.68
Fan, J.B.69
Gunderson, K.70
Murray, S.S.71
Oliphant, A.R.72
Chee, M.S.73
Montpetit, A.74
Chagnon, F.75
Ferretti, V.76
Leboeuf, M.77
Olivier, J.F.78
Phillips, M.S.79
Roumy, S.80
Sallée, C.81
Verner, A.82
Hudson, T.J.83
Kwok, P.Y.84
Cai, D.85
Koboldt, D.C.86
Miller, R.D.87
Pawlikowska, L.88
Taillon-Miller, P.89
Xiao, M.90
Tsui, L.C.91
Mak, W.92
Song, Y.Q.93
Tam, P.K.94
Nakamura, Y.95
Kawaguchi, T.96
Kitamoto, T.97
Morizono, T.98
Nagashima, A.99
more..
-
36
-
-
0033762062
-
Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway
-
Kang D.E., Pietrzik C.U., Baum L., Chevallier N., Merriam D.E., Kounnas M.Z., Wagner S.L., Troncoso J.C., Kawas C.H., Katzman R., Koo E.H. Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway. J. Clin. Invest. 2000, 106:1159-1166.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1159-1166
-
-
Kang, D.E.1
Pietrzik, C.U.2
Baum, L.3
Chevallier, N.4
Merriam, D.E.5
Kounnas, M.Z.6
Wagner, S.L.7
Troncoso, J.C.8
Kawas, C.H.9
Katzman, R.10
Koo, E.H.11
-
37
-
-
0037145062
-
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis
-
Kang D.E., Soriano S., Xia X., Eberhart C.G., De Strooper B., Zheng H., Koo E.H. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell 2002, 110:751-762.
-
(2002)
Cell
, vol.110
, pp. 751-762
-
-
Kang, D.E.1
Soriano, S.2
Xia, X.3
Eberhart, C.G.4
De Strooper, B.5
Zheng, H.6
Koo, E.H.7
-
38
-
-
0032446373
-
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E
-
Kim D.H., Inagaki Y., Suzuki T., Ioka R.X., Yoshioka S.Z., Magoori K., Kang M.J., Cho Y., Nakano A.Z., Liu Q., Fujino T., Suzuki H., Sasano H., Yamamoto T.T. A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E. J. Biochem. 1998, 124:1072-1076.
-
(1998)
J. Biochem.
, vol.124
, pp. 1072-1076
-
-
Kim, D.H.1
Inagaki, Y.2
Suzuki, T.3
Ioka, R.X.4
Yoshioka, S.Z.5
Magoori, K.6
Kang, M.J.7
Cho, Y.8
Nakano, A.Z.9
Liu, Q.10
Fujino, T.11
Suzuki, H.12
Sasano, H.13
Yamamoto, T.T.14
-
39
-
-
0027193190
-
Alterations of glial fibrillary acidic protein mRNA level in the aging brain and in senile dementia of the Alzheimer type
-
Le Prince G., Delaere P., Fages C., Duyckaerts C., Hauw J.J., Tardy M. Alterations of glial fibrillary acidic protein mRNA level in the aging brain and in senile dementia of the Alzheimer type. Neurosci. Lett. 1993, 151:71-73.
-
(1993)
Neurosci. Lett.
, vol.151
, pp. 71-73
-
-
Le Prince, G.1
Delaere, P.2
Fages, C.3
Duyckaerts, C.4
Hauw, J.J.5
Tardy, M.6
-
40
-
-
33644870413
-
Glycogen synthase kinase 3beta phosphorylates Alzheimer's disease-specific Ser396 of microtubule-associated protein tau by a sequential mechanism
-
Li T., Paudel H.K. Glycogen synthase kinase 3beta phosphorylates Alzheimer's disease-specific Ser396 of microtubule-associated protein tau by a sequential mechanism. Biochemistry 2006, 45:3125-3133.
-
(2006)
Biochemistry
, vol.45
, pp. 3125-3133
-
-
Li, T.1
Paudel, H.K.2
-
41
-
-
25844432119
-
Wnt signalling regulates adult hippocampal neurogenesis
-
Lie D.C., Colamarino S.A., Song H.J., Désiré L., Mira H., Consiglio A., Lein E.S., Jessberger S., Lansford H., Dearie A.R., Gage F.H. Wnt signalling regulates adult hippocampal neurogenesis. Nature 2005, 437:1370-1375.
-
(2005)
Nature
, vol.437
, pp. 1370-1375
-
-
Lie, D.C.1
Colamarino, S.A.2
Song, H.J.3
Désiré, L.4
Mira, H.5
Consiglio, A.6
Lein, E.S.7
Jessberger, S.8
Lansford, H.9
Dearie, A.R.10
Gage, F.H.11
-
42
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
43
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone S., Reynolds C.H., Latimer D., Davis D.R., Anderton B.H., Gallo J.M., Hanger D., Mulot S., Marquardt B., Stabel S., Woodgett J.R., Miller C.J. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 1994, 4:1077-1086.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
Reynolds, C.H.2
Latimer, D.3
Davis, D.R.4
Anderton, B.H.5
Gallo, J.M.6
Hanger, D.7
Mulot, S.8
Marquardt, B.9
Stabel, S.10
Woodgett, J.R.11
Miller, C.J.12
-
44
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
Lucas J.J., Hernández F., Gómez-Ramos P., Morán M.A., Hen R., Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J. 2001, 20:27-39.
-
(2001)
EMBO J.
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernández, F.2
Gómez-Ramos, P.3
Morán, M.A.4
Hen, R.5
Avila, J.6
-
45
-
-
33847656105
-
LRP6 mutation in a family with early coronary disease and metabolic risk factors
-
Mani A., Radhakrishnan J., Wang H., Mani A., Mani M.A., Nelson-Williams C., Carew K.S., Mane S., Najmabadi H., Wu D., Lifton R.P. LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science 2007, 315:1278-1282.
-
(2007)
Science
, vol.315
, pp. 1278-1282
-
-
Mani, A.1
Radhakrishnan, J.2
Wang, H.3
Mani, A.4
Mani, M.A.5
Nelson-Williams, C.6
Carew, K.S.7
Mane, S.8
Najmabadi, H.9
Wu, D.10
Lifton, R.P.11
-
46
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
-
Mao J., Wang J., Liu B., Pan W., Farr G.H., Flynn C., Yuan H., Takada S., Kimelman D., Li L., Wu D. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol. Cell. 2001, 7:801-809.
-
(2001)
Mol. Cell.
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr, G.H.5
Flynn, C.6
Yuan, H.7
Takada, S.8
Kimelman, D.9
Li, L.10
Wu, D.11
-
47
-
-
33645720958
-
Association between glycogen synthase kinase-3beta genetic polymorphism and late-onset Alzheimer's disease
-
Mateo I., Infante J., Llorca J., Rodríguez E., Berciano J., Combarros O. Association between glycogen synthase kinase-3beta genetic polymorphism and late-onset Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 2006, 21:228-232.
-
(2006)
Dement. Geriatr. Cogn. Disord.
, vol.21
, pp. 228-232
-
-
Mateo, I.1
Infante, J.2
Llorca, J.3
Rodríguez, E.4
Berciano, J.5
Combarros, O.6
-
48
-
-
34447527687
-
Expression of APP pathway mRNAs and proteins in Alzheimer's disease
-
Matsui T., Ingelsson M., Fukumoto H., Ramasamy K., Kowa H., Frosch M.P., Irizarry M.C., Hyman B.T. Expression of APP pathway mRNAs and proteins in Alzheimer's disease. Brain Res. 2007, 1161:116-123.
-
(2007)
Brain Res.
, vol.1161
, pp. 116-123
-
-
Matsui, T.1
Ingelsson, M.2
Fukumoto, H.3
Ramasamy, K.4
Kowa, H.5
Frosch, M.P.6
Irizarry, M.C.7
Hyman, B.T.8
-
49
-
-
0038617729
-
Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss
-
Modrek B., Lee C.J. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat. Genet. 2003, 34:177-180.
-
(2003)
Nat. Genet.
, vol.34
, pp. 177-180
-
-
Modrek, B.1
Lee, C.J.2
-
50
-
-
4344584730
-
WNT and beta-catenin signalling: diseases and therapies
-
Moon R.T., Kohn A.D., De Ferrari G.V., Kaykas A. WNT and beta-catenin signalling: diseases and therapies. Nat. Rev. Genet. 2004, 5:691-701.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
De Ferrari, G.V.3
Kaykas, A.4
-
51
-
-
0035879075
-
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase
-
Mudher A., Chapman S., Richardson J., Asuni A., Gibb G., Pollard C., Killick R., Iqbal T., Raymond L., Varndell I., Sheppard P., Makoff A., Gower E., Soden P.E., Lewis P., Murphy M., Golde T.E., Rupniak H.T., Anderton B.H., Lovestone S. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. J. Neurosci. 2001, 21:4987-4995.
-
(2001)
J. Neurosci.
, vol.21
, pp. 4987-4995
-
-
Mudher, A.1
Chapman, S.2
Richardson, J.3
Asuni, A.4
Gibb, G.5
Pollard, C.6
Killick, R.7
Iqbal, T.8
Raymond, L.9
Varndell, I.10
Sheppard, P.11
Makoff, A.12
Gower, E.13
Soden, P.E.14
Lewis, P.15
Murphy, M.16
Golde, T.E.17
Rupniak, H.T.18
Anderton, B.H.19
Lovestone, S.20
more..
-
52
-
-
0036150827
-
Alzheimer's disease-do tauists and baptists finally shake hands?
-
Mudher A., Lovestone S. Alzheimer's disease-do tauists and baptists finally shake hands?. Trends Neurosci. 2002, 25:22-26.
-
(2002)
Trends Neurosci.
, vol.25
, pp. 22-26
-
-
Mudher, A.1
Lovestone, S.2
-
53
-
-
36549053104
-
A survey of genetic human cortical gene expression
-
Myers A.J., Gibbs J.R., Webster J.A., Rohrer K., Zhao A., Marlowe L., Kaleem M., Leung D., Bryden L., Nath P., Zismann V.L., Joshipura K., Huentelman M.J., Hu-Lince D., Coon K.D., Craig D.W., Pearson J.V., Holmans P., Heward C.B., Reiman E.M., Stephan D., Hardy J. A survey of genetic human cortical gene expression. Nat. Genet. 2007, 39:1494-1499.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1494-1499
-
-
Myers, A.J.1
Gibbs, J.R.2
Webster, J.A.3
Rohrer, K.4
Zhao, A.5
Marlowe, L.6
Kaleem, M.7
Leung, D.8
Bryden, L.9
Nath, P.10
Zismann, V.L.11
Joshipura, K.12
Huentelman, M.J.13
Hu-Lince, D.14
Coon, K.D.15
Craig, D.W.16
Pearson, J.V.17
Holmans, P.18
Heward, C.B.19
Reiman, E.M.20
Stephan, D.21
Hardy, J.22
more..
-
54
-
-
18344378499
-
Lipoprotein particles are required for Hedgehog and Wingless signalling
-
Panakova D., Sprong H., Marois E., Thiele C., Eaton S. Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature 2005, 435:58-65.
-
(2005)
Nature
, vol.435
, pp. 58-65
-
-
Panakova, D.1
Sprong, H.2
Marois, E.3
Thiele, C.4
Eaton, S.5
-
55
-
-
0032850599
-
Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes
-
Pei J.J., Braak E., Braak H., Grundke-Iqbal I., Iqbal K., Winblad B., Cowburn R.F. Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes. J. Neuropathol. Exp. Neurol. 1999, 58:1010-1019.
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 1010-1019
-
-
Pei, J.J.1
Braak, E.2
Braak, H.3
Grundke-Iqbal, I.4
Iqbal, K.5
Winblad, B.6
Cowburn, R.F.7
-
56
-
-
1842483281
-
Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper-Excel-based tool using pair-wise correlations
-
Pfaffl M.W., Tichopad A., Prgomet C., Neuvians T.P. Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper-Excel-based tool using pair-wise correlations. Biotechnol. Lett. 2004, 26:509-515.
-
(2004)
Biotechnol. Lett.
, vol.26
, pp. 509-515
-
-
Pfaffl, M.W.1
Tichopad, A.2
Prgomet, C.3
Neuvians, T.P.4
-
57
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel C.J., Wilson C.A., Lee V.M., Klein P.S. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 2003, 423:435-439.
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
59
-
-
33846468343
-
Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression
-
Pospisil H., Herrmann A., Butherus K., Pirson S., Reich J.G., Kemmner W. Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression. BMC Genomics 2006, 7:148.
-
(2006)
BMC Genomics
, vol.7
, pp. 148
-
-
Pospisil, H.1
Herrmann, A.2
Butherus, K.3
Pirson, S.4
Reich, J.G.5
Kemmner, W.6
-
60
-
-
51649085383
-
Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli
-
Purro S.A., Ciani L., Hoyos-Flight M., Stamatakou E., Siomou E., Salinas P.C. Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli. J. Neurosci. 2008, 28:8644-8654.
-
(2008)
J. Neurosci.
, vol.28
, pp. 8644-8654
-
-
Purro, S.A.1
Ciani, L.2
Hoyos-Flight, M.3
Stamatakou, E.4
Siomou, E.5
Salinas, P.C.6
-
61
-
-
78751555838
-
Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication
-
Riancho J.A., Olmos J.M., Pineda B., García-Ibarbia C., Pérez-Núñez M.I., Nan D.N., Velasco J., Cano A., García-Pérez M.A., Zarrabeitia M.T., González-Macías J. Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication. Eur. J. Endocrinol. 2011, 164:123-131.
-
(2011)
Eur. J. Endocrinol.
, vol.164
, pp. 123-131
-
-
Riancho, J.A.1
Olmos, J.M.2
Pineda, B.3
García-Ibarbia, C.4
Pérez-Núñez, M.I.5
Nan, D.N.6
Velasco, J.7
Cano, A.8
García-Pérez, M.A.9
Zarrabeitia, M.T.10
González-Macías, J.11
-
62
-
-
0038692293
-
Quantification of regional glial fibrillary acidic protein levels in Alzheimer's disease
-
Ross G.W., O'Callaghan J.P., Sharp D.S., Petrovitch H., Miller D.B., Abbott R.D., Nelson J., Launer L.J., Foley D.J., Burchfiel C.M., Hardman J., White L.R. Quantification of regional glial fibrillary acidic protein levels in Alzheimer's disease. Acta Neurol. Scand. 2003, 107:318-323.
-
(2003)
Acta Neurol. Scand.
, vol.107
, pp. 318-323
-
-
Ross, G.W.1
O'Callaghan, J.P.2
Sharp, D.S.3
Petrovitch, H.4
Miller, D.B.5
Abbott, R.D.6
Nelson, J.7
Launer, L.J.8
Foley, D.J.9
Burchfiel, C.M.10
Hardman, J.11
White, L.R.12
-
63
-
-
0035062230
-
Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 beta gene and promoter in late onset Alzheimer's disease
-
Russ C., Lovestone S., Powell J.F. Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 beta gene and promoter in late onset Alzheimer's disease. Mol. Psychiatry 2001, 6:320-324.
-
(2001)
Mol. Psychiatry
, vol.6
, pp. 320-324
-
-
Russ, C.1
Lovestone, S.2
Powell, J.F.3
-
64
-
-
0036150938
-
Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease
-
Russ C., Lovestone S., Powell J.F. Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease. Mol. Psychiatry 2002, 7:104-109.
-
(2002)
Mol. Psychiatry
, vol.7
, pp. 104-109
-
-
Russ, C.1
Lovestone, S.2
Powell, J.F.3
-
65
-
-
35349012592
-
Genome-wide detection and characterization of positive selection in human populations
-
International HapMap Consortium
-
Sabeti P.C., Varilly P., Fry B., Lohmueller J., Hostetter E., Cotsapas C., Xie X., Byrne E.H., McCarroll S.A., Gaudet R., Schaffner S.F., Lander E.S., Frazer K.A., Ballinger D.G., Cox D.R., Hinds D.A., Stuve L.L., Gibbs R.A., Belmont J.W., Boudreau A., Hardenbol P., Leal S.M., Pasternak S., Wheeler D.A., Willis T.D., Yu F., Yang H., Zeng C., Gao Y., Hu H., Hu W., Li C., Lin W., Liu S., Pan H., Tang X., Wang J., Wang W., Yu J., Zhang B., Zhang Q., Zhao H., Zhao H., Zhou J., Gabriel S.B., Barry R., Blumenstiel B., Camargo A., Defelice M., Faggart M., Goyette M., Gupta S., Moore J., Nguyen H., Onofrio R.C., Parkin M., Roy J., Stahl E., Winchester E., Ziaugra L., Altshuler D., Shen Y., Yao Z., Huang W., Chu X., He Y., Jin L., Liu Y., Shen Y., Sun W., Wang H., Wang Y., Wang Y., Xiong X., Xu L., Waye M.M., Tsui S.K., Xue H., Wong J.T., Galver L.M., Fan J.B., Gunderson K., Murray S.S., Oliphant A.R., Chee M.S., Montpetit A., Chagnon F., Ferretti V., Leboeuf M., Olivier J.F., Phillips M.S., Roumy S., Sallée C., Verner A., Hudson T.J., Kwok P.Y., Cai D., Koboldt D.C., Miller R.D., Pawlikowska L., Taillon-Miller P., Xiao M., Tsui L.C., Mak W., Song Y.Q., Tam P.K., Nakamura Y., Kawaguchi T., Kitamoto T., Morizono T., Nagashima A., Ohnishi Y., Sekine A., Tanaka T., Tsunoda T., Deloukas P., Bird C.P., Delgado M., Dermitzakis E.T., Gwilliam R., Hunt S., Morrison J., Powell D., Stranger B.E., Whittaker P., Bentley D.R., Daly M.J., de Bakker P.I., Barrett J., Chretien Y.R., Maller J., McCarroll S., Patterson N., Pe'er I., Price A., Purcell S., Richter D.J., Sabeti P., Saxena R., Schaffner S.F., Sham P.C., Varilly P., Altshuler D., Stein L.D., Krishnan L., Smith A.V., Tello-Ruiz M.K., Thorisson G.A., Chakravarti A., Chen P.E., Cutler D.J., Kashuk C.S., Lin S., Abecasis G.R., Guan W., Li Y., Munro H.M., Qin Z.S., Thomas D.J., McVean G., Auton A., Bottolo L., Cardin N., Eyheramendy S., Freeman C., Marchini J., Myers S., Spencer C., Stephens M., Donnelly P., Cardon L.R., Clarke G., Evans D.M., Morris A.P., Weir B.S., Tsunoda T., Johnson T.A., Mullikin J.C., Sherry S.T., Feolo M., Skol A., Zhang H., Zeng C., Zhao H., Matsuda I., Fukushima Y., Macer D.R., Suda E., Rotimi C.N., Adebamowo C.A., Ajayi I., Aniagwu T., Marshall P.A., Nkwodimmah C., Royal C.D., Leppert M.F., Dixon M., Peiffer A., Qiu R., Kent A., Kato K., Niikawa N., Adewole I.F., Knoppers B.M., Foster M.W., Clayton E.W., Watkin J., Gibbs R.A., Belmont J.W., Muzny D., Nazareth L., Sodergren E., Weinstock G.M., Wheeler D.A., Yakub I., Gabriel S.B., Onofrio R.C., Richter D.J., Ziaugra L., Birren B.W., Daly M.J., Altshuler D., Wilson R.K., Fulton L.L., Rogers J., Burton J., Carter N.P., Clee C.M., Griffiths M., Jones M.C., McLay K., Plumb R.W., Ross M.T., Sims S.K., Willey D.L., Chen Z., Han H., Kang L., Godbout M., Wallenburg J.C., L'Archevêque P., Bellemare G., Saeki K., Wang H., An D., Fu H., Li Q., Wang Z., Wang R., Holden A.L., Brooks L.D., McEwen J.E., Guyer M.S., Wang V.O., Peterson J.L., Shi M., Spiegel J., Sung L.M., Zacharia L.F., Collins F.S., Kennedy K., Jamieson R., Stewart J. Genome-wide detection and characterization of positive selection in human populations. Nature 2007, 449:913-918. International HapMap Consortium.
-
(2007)
Nature
, vol.449
, pp. 913-918
-
-
Sabeti, P.C.1
Varilly, P.2
Fry, B.3
Lohmueller, J.4
Hostetter, E.5
Cotsapas, C.6
Xie, X.7
Byrne, E.H.8
McCarroll, S.A.9
Gaudet, R.10
Schaffner, S.F.11
Lander, E.S.12
Frazer, K.A.13
Ballinger, D.G.14
Cox, D.R.15
Hinds, D.A.16
Stuve, L.L.17
Gibbs, R.A.18
Belmont, J.W.19
Boudreau, A.20
Hardenbol, P.21
Leal, S.M.22
Pasternak, S.23
Wheeler, D.A.24
Willis, T.D.25
Yu, F.26
Yang, H.27
Zeng, C.28
Gao, Y.29
Hu, H.30
Hu, W.31
Li, C.32
Lin, W.33
Liu, S.34
Pan, H.35
Tang, X.36
Wang, J.37
Wang, W.38
Yu, J.39
Zhang, B.40
Zhang, Q.41
Zhao, H.42
Zhao, H.43
Zhou, J.44
Gabriel, S.B.45
Barry, R.46
Blumenstiel, B.47
Camargo, A.48
Defelice, M.49
Faggart, M.50
Goyette, M.51
Gupta, S.52
Moore, J.53
Nguyen, H.54
Onofrio, R.C.55
Parkin, M.56
Roy, J.57
Stahl, E.58
Winchester, E.59
Ziaugra, L.60
Altshuler, D.61
Shen, Y.62
Yao, Z.63
Huang, W.64
Chu, X.65
He, Y.66
Jin, L.67
Liu, Y.68
Shen, Y.69
Sun, W.70
Wang, H.71
Wang, Y.72
Wang, Y.73
Xiong, X.74
Xu, L.75
Waye, M.M.76
Tsui, S.K.77
Xue, H.78
Wong, J.T.79
Galver, L.M.80
Fan, J.B.81
Gunderson, K.82
Murray, S.S.83
Oliphant, A.R.84
Chee, M.S.85
Montpetit, A.86
Chagnon, F.87
Ferretti, V.88
Leboeuf, M.89
Olivier, J.F.90
Phillips, M.S.91
Roumy, S.92
Sallée, C.93
Verner, A.94
Hudson, T.J.95
Kwok, P.Y.96
Cai, D.97
Koboldt, D.C.98
Miller, R.D.99
more..
-
66
-
-
0036830458
-
Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells
-
Sato S., Tatebayashi Y., Akagi T., Chui D.H., Murayama M., Miyasaka T., Planel E., Tanemura K., Sun X., Hashikawa T., Yoshioka K., Ishiguro K., Takashima A. Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells. J. Biol. Chem. 2002, 277:42060-42065.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42060-42065
-
-
Sato, S.1
Tatebayashi, Y.2
Akagi, T.3
Chui, D.H.4
Murayama, M.5
Miyasaka, T.6
Planel, E.7
Tanemura, K.8
Sun, X.9
Hashikawa, T.10
Yoshioka, K.11
Ishiguro, K.12
Takashima, A.13
-
67
-
-
0037413694
-
Gene structure and alternative splicing of glycogen synthase kinase 3 beta (GSK-3beta) in neural and non-neural tissues
-
Schaffer B., Wiedau-Pazos M., Geschwind D.H. Gene structure and alternative splicing of glycogen synthase kinase 3 beta (GSK-3beta) in neural and non-neural tissues. Gene 2003, 302:73-81.
-
(2003)
Gene
, vol.302
, pp. 73-81
-
-
Schaffer, B.1
Wiedau-Pazos, M.2
Geschwind, D.H.3
-
68
-
-
34548738566
-
Population genomics of human gene expression
-
Stranger B.E., Nica A.C., Forrest M.S., Dimas A., Bird C.P., Beazley C., Ingle C.E., Dunning M., Flicek P., Koller D., Montgomery S., Tavaré S., Deloukas P., Dermitzakis E.T. Population genomics of human gene expression. Nat. Genet. 2007, 39:1217-1224.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1217-1224
-
-
Stranger, B.E.1
Nica, A.C.2
Forrest, M.S.3
Dimas, A.4
Bird, C.P.5
Beazley, C.6
Ingle, C.E.7
Dunning, M.8
Flicek, P.9
Koller, D.10
Montgomery, S.11
Tavaré, S.12
Deloukas, P.13
Dermitzakis, E.T.14
-
69
-
-
0037087220
-
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
-
Sun X., Murayama O., Murayama M., Park J.M., Yamaguchi H., Takashima A. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 2002, 321:61-64.
-
(2002)
Neurosci. Lett.
, vol.321
, pp. 61-64
-
-
Sun, X.1
Murayama, O.2
Murayama, M.3
Park, J.M.4
Yamaguchi, H.5
Takashima, A.6
-
70
-
-
0031695652
-
Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
-
Takashima A., Honda T., Yasutake K., Michel G., Murayama O., Murayama M., Ishiguro K., Yamaguchi H. Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons. Neurosci. Res. 1998, 31:317-323.
-
(1998)
Neurosci. Res.
, vol.31
, pp. 317-323
-
-
Takashima, A.1
Honda, T.2
Yasutake, K.3
Michel, G.4
Murayama, O.5
Murayama, M.6
Ishiguro, K.7
Yamaguchi, H.8
-
71
-
-
13144265717
-
Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau
-
Takashima A., Murayama M., Murayama O., Kohno T., Honda T., Yasutake K., Nihonmatsu N., Mercken M., Yamaguchi H., Sugihara S., Wolozin B. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:9637-9641.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 9637-9641
-
-
Takashima, A.1
Murayama, M.2
Murayama, O.3
Kohno, T.4
Honda, T.5
Yasutake, K.6
Nihonmatsu, N.7
Mercken, M.8
Yamaguchi, H.9
Sugihara, S.10
Wolozin, B.11
-
72
-
-
16844362466
-
Synaptic contact dynamics controlled by cadherin and catenins
-
Takeichi M., Abe K. Synaptic contact dynamics controlled by cadherin and catenins. Trends Cell Biol. 2005, 15:216-221.
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 216-221
-
-
Takeichi, M.1
Abe, K.2
-
73
-
-
69849086878
-
A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol
-
Tomaszewski M., Charchar F.J., Barnes T., Gawron-Kiszka M., Sedkowska A., Podolecka E., Kowalczyk J., Rathbone W., Kalarus Z., Grzeszczak W., Goodall A.H., Samani N.J., Zukowska-Szczechowska E. A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol. Arterioscler. Thromb. Vasc. Biol. 2009, 29:1316-1321.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 1316-1321
-
-
Tomaszewski, M.1
Charchar, F.J.2
Barnes, T.3
Gawron-Kiszka, M.4
Sedkowska, A.5
Podolecka, E.6
Kowalczyk, J.7
Rathbone, W.8
Kalarus, Z.9
Grzeszczak, W.10
Goodall, A.H.11
Samani, N.J.12
Zukowska-Szczechowska, E.13
-
74
-
-
79251644774
-
Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease
-
Twine N.A., Janitz K., Wilkins M.R., Janitz M. Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease. PLoS One 2011, 6:e16266.
-
(2011)
PLoS One
, vol.6
-
-
Twine, N.A.1
Janitz, K.2
Wilkins, M.R.3
Janitz, M.4
-
75
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3. RESEARCH0034.
-
(2002)
Genome Biol.
, vol.3
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
De Paepe, A.6
Speleman, F.7
-
76
-
-
29644446220
-
Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men
-
van Meurs J.B., Rivadeneira F., Jhamai M., Hugens W., Hofman A., van Leeuwen J.P., Pols H.A., Uitterlinden A.G. Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men. J. Bone. Miner. Res. 2006, 21:141-150.
-
(2006)
J. Bone. Miner. Res.
, vol.21
, pp. 141-150
-
-
van Meurs, J.B.1
Rivadeneira, F.2
Jhamai, M.3
Hugens, W.4
Hofman, A.5
van Leeuwen, J.P.6
Pols, H.A.7
Uitterlinden, A.G.8
-
77
-
-
64149105182
-
Genetic control of human brain transcript expression in Alzheimer disease
-
NACC-Neuropathology Group
-
Webster J.A., Gibbs J.R., Clarke J., Ray M., Zhang W., Holmans P., Rohrer K., Zhao A., Marlowe L., Kaleem M., McCorquodale D.S., Cuello C., Leung D., Bryden L., Nath P., Zismann V.L., Joshipura K., Huentelman M.J., Hu-Lince D., Coon K.D., Craig D.W., Pearson J.V., Heward C.B., Reiman E.M., Stephan D., Hardy J., Myers A.J. Genetic control of human brain transcript expression in Alzheimer disease. Am. J. Hum. Genet. 2009, 84:445-458. NACC-Neuropathology Group.
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 445-458
-
-
Webster, J.A.1
Gibbs, J.R.2
Clarke, J.3
Ray, M.4
Zhang, W.5
Holmans, P.6
Rohrer, K.7
Zhao, A.8
Marlowe, L.9
Kaleem, M.10
McCorquodale, D.S.11
Cuello, C.12
Leung, D.13
Bryden, L.14
Nath, P.15
Zismann, V.L.16
Joshipura, K.17
Huentelman, M.J.18
Hu-Lince, D.19
Coon, K.D.20
Craig, D.W.21
Pearson, J.V.22
Heward, C.B.23
Reiman, E.M.24
Stephan, D.25
Hardy, J.26
Myers, A.J.27
more..
-
79
-
-
0032531793
-
Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis
-
Zhang Z., Hartmann H., Do V.M., Abramowski D., Sturchler-Pierrat C., Staufenbiel M., Sommer B., van de Wetering M., Clevers H., Saftig P., De Strooper B., He X., Yankner B.A. Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 1998, 395:698-702.
-
(1998)
Nature
, vol.395
, pp. 698-702
-
-
Zhang, Z.1
Hartmann, H.2
Do, V.M.3
Abramowski, D.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Sommer, B.7
van de Wetering, M.8
Clevers, H.9
Saftig, P.10
De Strooper, B.11
He, X.12
Yankner, B.A.13
-
80
-
-
0030788767
-
Presenilin 1 interaction in the brain with a novel member of the Armadillo family
-
Zhou J., Liyanage U., Medina M., Ho C., Simmons A.D., Lovett M., Kosik K.S. Presenilin 1 interaction in the brain with a novel member of the Armadillo family. Neuroreport 1997, 8:2085-2090.
-
(1997)
Neuroreport
, vol.8
, pp. 2085-2090
-
-
Zhou, J.1
Liyanage, U.2
Medina, M.3
Ho, C.4
Simmons, A.D.5
Lovett, M.6
Kosik, K.S.7
|