-
1
-
-
0034172698
-
The genetics of Alzheimer's disease
-
Schellenberg, G.D., D'Souza, I. and Poorkaj, P. (2000) The genetics of Alzheimer's disease. Curr. Psych. Rep., 2, 158-164.
-
(2000)
Curr. Psych. Rep.
, vol.2
, pp. 158-164
-
-
Schellenberg, G.D.1
D'Souza, I.2
Poorkaj, P.3
-
2
-
-
0030893280
-
The role of heredity in late-onset Alzheimer disease and vascular dementia. A twin study
-
Bergem, A.L., Engedal, K. and Kringlen, E. (1997) The role of heredity in late-onset Alzheimer disease and vascular dementia. A twin study. Arch. Gen. Psych., 54, 264-270.
-
(1997)
Arch. Gen. Psych.
, vol.54
, pp. 264-270
-
-
Bergem, A.L.1
Engedal, K.2
Kringlen, E.3
-
3
-
-
18844479720
-
Heritability for Alzheimer's disease: The study of dementia in Swedish twins
-
Gatz, M., Pedersen, N.L., Berg, S., Johansson, B., Johansson, K., Mortimer, J.A., Posner, S.F., Viitanen, M., Winblad, B. and Ahlbom, A. (1997) Heritability for Alzheimer's disease: the study of dementia in Swedish twins. J Gerontol. A. Biol. Sci. Med. Sci., 52, M117-1125.
-
(1997)
J. Gerontol. A. Biol. Sci. Med. Sci.
, vol.52
-
-
Gatz, M.1
Pedersen, N.L.2
Berg, S.3
Johansson, B.4
Johansson, K.5
Mortimer, J.A.6
Posner, S.F.7
Viitanen, M.8
Winblad, B.9
Ahlbom, A.10
-
4
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder, E.H., Saunders, A.M., Strittmatter, W.J., Schmechel, D.E., Gaskell, P.C., Small, G.W., Roses, A.D., Haines, J.L. and Pericak-Vance, M.A. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science, 261, 921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
5
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer, L.A., Cupples, L.A., Haines, J.L., Hyman, B., Kukull, W.A., Mayeux, R., Myers, R.H., Pericak-Vance, M.A., Risch, N. and Duijn, C.M. (1997) Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA, 278, 1349-1356.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericak-Vance, M.A.8
Risch, N.9
Duijn, C.M.10
-
6
-
-
0033926434
-
The number of trait loci in late-onset Alzheimer disease
-
Warwick-Daw, E., Payami, H., Nemens, E.J., Nochlin, D., Bird, T.D., Schellenberg, G.D. and Wijsman, E.M. (2000) The number of trait loci in late-onset Alzheimer disease. Am. J. Hum. Genet., 66, 196-204.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 196-204
-
-
Warwick-Daw, E.1
Payami, H.2
Nemens, E.J.3
Nochlin, D.4
Bird, T.D.5
Schellenberg, G.D.6
Wijsman, E.M.7
-
7
-
-
0035220056
-
Variance component methods for detecting complex trait loci
-
Blangero, J., Williams, J.T. and Almasy, L. (2001) Variance component methods for detecting complex trait loci. Adv. Genet., 42, 151-181.
-
(2001)
Adv. Genet.
, vol.42
, pp. 151-181
-
-
Blangero, J.1
Williams, J.T.2
Almasy, L.3
-
8
-
-
0029875956
-
The geneticist's approach to complex disease
-
Ghosh, S. and Collins, F.S. (1996) The geneticist's approach to complex disease. Annu. Rev. Med., 47, 333-353.
-
(1996)
Annu. Rev. Med.
, vol.47
, pp. 333-353
-
-
Ghosh, S.1
Collins, F.S.2
-
9
-
-
0031831322
-
Sometimes it's hot, sometimes it's not
-
Lernmark, A. and Ott, J. (1998) Sometimes it's hot, sometimes it's not. Nat. Genet., 19, 213-214.
-
(1998)
Nat. Genet.
, vol.19
, pp. 213-214
-
-
Lernmark, A.1
Ott, J.2
-
10
-
-
0026760261
-
Production of the Alzheimer amyloid β protein by normal proteolytic processing
-
Shoji, M., Golde, T.E., Cheung, T.T., Ghiso, J., Estus, S., Shaffer, L.M., Cai, X.-D., McKay, D., Tintner, R., Frangione, B. et al. (1992) Production of the Alzheimer amyloid β protein by normal proteolytic processing. Science, 258, 126-129.
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.E.2
Cheung, T.T.3
Ghiso, J.4
Estus, S.5
Shaffer, L.M.6
Cai, X.-D.7
McKay, D.8
Tintner, R.9
Frangione, B.10
-
11
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schlossmacher, M., Whaley, J., Swindlehurst, C. et al. (1992) Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature, 359, 325-327.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
-
12
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass, C., Schlossmacher, M.G., Hung, A.Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B.L., Lieberburg, I., Koo, E.H., Schenk, D., Teplow, D.B. et al. (1992) Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature, 359, 322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
-
13
-
-
0027258149
-
Cells with a familial Alzheimer's disease mutation produce authentic beta-peptide
-
Dovey, H.F., Suomensaari-Chrysler, S., Lieberburg, I., Sinha, S. and Keim, P.S. (1993) Cells with a familial Alzheimer's disease mutation produce authentic beta-peptide. Neuroreport, 4, 1039-1042.
-
(1993)
Neuroreport
, vol.4
, pp. 1039-1042
-
-
Dovey, H.F.1
Suomensaari-Chrysler, S.2
Lieberburg, I.3
Sinha, S.4
Keim, P.S.5
-
14
-
-
0027379395
-
Characterization of beta-amyloid peptide from human cerebrospinal fluid
-
Vigo-Pelfrey, C., Lee, D., Keim, P., Lieberburg, I. and Schenk, D.B. (1993) Characterization of beta-amyloid peptide from human cerebrospinal fluid. J. Neurochem., 61, 1965-1968.
-
(1993)
J. Neurochem.
, vol.61
, pp. 1965-1968
-
-
Vigo-Pelfrey, C.1
Lee, D.2
Keim, P.3
Lieberburg, I.4
Schenk, D.B.5
-
15
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki, N., Cheung, T.T., Cai, X.D., Odaka, A., Otvos, L., Jr, Eckman, C., Golde, T.E. and Younkin, S.G. (1994) An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science, 264, 1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
16
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. and Stadlan, E.M. (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34, 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
17
-
-
0028915895
-
Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta40 or A beta 42(43)
-
Gravina, S.A., Ho, L., Eckman, C.B., Long, K.E., Otvos, L., Younkin, L.H., Suzuki, N. and Younkin, S.G. (1995) Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta40 or A beta 42(43). J. Biol. Chem., 270, 7013-7016.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7013-7016
-
-
Gravina, S.A.1
Ho, L.2
Eckman, C.B.3
Long, K.E.4
Otvos, L.5
Younkin, L.H.6
Suzuki, N.7
Younkin, S.G.8
-
18
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett, J.T., Berger, E.P. and Lansbury P.T., Jr (1993) The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry, 32, 4693-4697.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr., P.T.3
-
19
-
-
0028168336
-
Amyloid-beta aggregation: Selective inhibition of aggregation in mixtures of amyloid with different chain lengths
-
Snyder, S.W., Ladror, U.S., Wade, W.S., Wang, G.T., Barrett, L.W., Matayoshi, E.D., Huffaker, H.J., Krafft, G.A. and Holzman, T.F. (1994) Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths. Biophys. J., 67, 1216-1228.
-
(1994)
Biophys. J.
, vol.67
, pp. 1216-1228
-
-
Snyder, S.W.1
Ladror, U.S.2
Wade, W.S.3
Wang, G.T.4
Barrett, L.W.5
Matayoshi, E.D.6
Huffaker, H.J.7
Krafft, G.A.8
Holzman, T.F.9
-
20
-
-
0023192563
-
Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease
-
Bahmanyar, S., Higgins, G.A., Goldgaber, D., Lewis, D.A., Morrison, J.H., Wilson, M.C., Shankar, S.K. and Gajdusek, D.C. (1987) Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease. Science, 237, 77-80.
-
(1987)
Science
, vol.237
, pp. 77-80
-
-
Bahmanyar, S.1
Higgins, G.A.2
Goldgaber, D.3
Lewis, D.A.4
Morrison, J.H.5
Wilson, M.C.6
Shankar, S.K.7
Gajdusek, D.C.8
-
21
-
-
0023109592
-
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
Tanzi, R.E., Gusella, J.F., Watkins, P.C., Bruns, G.A., St George-Hyslop, P., Van Keuren, M.L., Patterson, D., Pagan, S., Kurnit, D.M. and Neve, R.L. (1987) Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science, 235, 880-884.
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St George-Hyslop, P.5
Van Keuren, M.L.6
Patterson, D.7
Pagan, S.8
Kurnit, D.M.9
Neve, R.L.10
-
22
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate, A., Chartier-Harlin, M.C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L. et al. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature, 349, 704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
-
23
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D.M., Oshima, J., Pettingell, W.H., Yu, C.E., Jondro, P.D., Schmidt, S.D., Wang, K. et al. (1995) Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science, 269, 973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
-
24
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev, E.I., Sherrington, R., Rogaeva, E.A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, C., Holman, K., Tsuda, T. et al. (1995) Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature, 376, 775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
-
25
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington, R., Rogaev, E.I., Liang, Y., Rogaeva, E.A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K. et al. (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature, 375, 754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
-
26
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
Borchelt, D.R., Thinakaran, G., Eckman, C.B., Lee, M.K., Davenport, F., Ratovitsky T., Prada, C.M., Kim, G., Seekins, S., Yager, D. et al. (1996) Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron, 17, 1005-1013.
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
-
27
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
Cai, X.D., Golde, T.E. and Younkin, S.G. (1993) Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science, 259, 514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
28
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer'sdisease increases beta-protein production
-
Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A.Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I. and Selkoe, D.J. (1992) Mutation of the beta-amyloid precursor protein in familial Alzheimer'sdisease increases beta-protein production. Nature, 360, 672-674.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
29
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin1
-
Duff, K., Eckman, C., Zehr, C., Yu, X., Prada, C.M., Perez-Tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D. et al. (1996) Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin1. Nature, 383, 710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
-
30
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. and Cole, G. (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science, 274, 99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
31
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T.D., Hardy, J., Hutton, M., Kukull, W. et al. (1996) Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med., 2, 864-870.
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
-
32
-
-
0002349390
-
Role of elevated amyloid β protein in patients with typical late onset Alzheimer's disease
-
Younkin, S.G., Ertekin Taner, N., Xin, T., Baker, M., Younkin, L.H., Hutton, M. and Graff-Radford, N. (2000) Role of elevated amyloid β protein in patients with typical late onset Alzheimer's disease. Neurobiol. Aging, 21, S136.
-
(2000)
Neurobiol. Aging
, vol.21
-
-
Younkin, S.G.1
Ertekin Taner, N.2
Xin, T.3
Baker, M.4
Younkin, L.H.5
Hutton, M.6
Graff-Radford, N.7
-
33
-
-
0032869023
-
Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease
-
Mayeux, R., Tang, M.X., Jacobs, D.M., Manly, J., Bell, K., Merchant, C., Small, S.A., Stern, Y., Wisniewski, H.M. and Mehta, P.D. (1999) Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease. Ann. Neurol., 46, 412-416.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 412-416
-
-
Mayeux, R.1
Tang, M.X.2
Jacobs, D.M.3
Manly, J.4
Bell, K.5
Merchant, C.6
Small, S.A.7
Stern, Y.8
Wisniewski, H.M.9
Mehta, P.D.10
-
34
-
-
0034936365
-
Heritability of plasma Aβ levels in typical late onset Alzheimer's disease pedigrees
-
Ertekin-Taner, N., Graff-Radford, N., Younkin, L., Eckman, C., Adamson, J., Schaid, D., Blangero, J., Hutton, M. and Younkin, S. (2001) Heritability of plasma Aβ levels in typical late onset Alzheimer's disease pedigrees. Genet. Epidem., 21, 19-30.
-
(2001)
Genet. Epidem.
, vol.21
, pp. 19-30
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.3
Eckman, C.4
Adamson, J.5
Schaid, D.6
Blangero, J.7
Hutton, M.8
Younkin, S.9
-
35
-
-
0034703979
-
Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner, N., Graff-Radford, N., Younkin, L.H., Eckman, C., Baker, M., Adamson, J., Ronald, J., Blangero, J., Hutton, M. and Younkin, S.G. (2000) Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science, 290, 2303-2304.
-
(2000)
Science
, vol.290
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
Eckman, C.4
Baker, M.5
Adamson, J.6
Ronald, J.7
Blangero, J.8
Hutton, M.9
Younkin, S.G.10
-
36
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
Myers, A., Holmans, P., Marshall, H., Kwon, J., Meyer, D., Ramic, D., Shears, S., Booth, J., DeVrieze, F.W., Crook, R. et al. (2000) Susceptibility locus for Alzheimer's disease on chromosome 10. Science, 290, 2304-2305.
-
(2000)
Science
, vol.290
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshall, H.3
Kwon, J.4
Meyer, D.5
Ramic, D.6
Shears, S.7
Booth, J.8
DeVrieze, F.W.9
Crook, R.10
-
37
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
Bertram, L., Blacker, D., Mullin, K., Keeney, D., Jones, J., Basu, S., Yhu, S., McInnis, M.G., Go, R.C., Vekrellis, K. et al. (2000) Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science, 290, 2302-2303.
-
(2000)
Science
, vol.290
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.9
Vekrellis, K.10
-
38
-
-
18344393780
-
Age at onset in two common neurodegenerative diseases is genetically controlled
-
Li, Y.J., Scott, W.K., Hedges, D.J., Zhang, F., Gaskell, P.C., Nance, M.A., Watts, R.L., Hubble, J.P., Koller, W.C., Pahwa, R. et al. (2002) Age at onset in two common neurodegenerative diseases is genetically controlled. Am. J. Hum. Genet., 70, 985-993.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 985-993
-
-
Li, Y.J.1
Scott, W.K.2
Hedges, D.J.3
Zhang, F.4
Gaskell, P.C.5
Nance, M.A.6
Watts, R.L.7
Hubble, J.P.8
Koller, W.C.9
Pahwa, R.10
-
39
-
-
0034741031
-
AlphaT-catenin: A novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion
-
Janssens, B., Goossens, S., Staes, K., Gilbert, B., van Hengel, J., Colpaert, C., Bruyneel, E., Mareel, M. and van Roy, F. (2001) alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion. J. Cell. Sci., 114, 3177-3188.
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 3177-3188
-
-
Janssens, B.1
Goossens, S.2
Staes, K.3
Gilbert, B.4
van Hengel, J.5
Colpaert, C.6
Bruyneel, E.7
Mareel, M.8
van Roy, F.9
-
40
-
-
0032531793
-
Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis
-
Zhang, Z., Hartmann, H., Do, V.M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., van de Wetering, M., Clevers, H., Saftig, P. et al. (1998) Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature, 395, 698-702.
-
(1998)
Nature
, vol.395
, pp. 698-702
-
-
Zhang, Z.1
Hartmann, H.2
Do, V.M.3
Abramowski, D.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Sommer, B.7
van de Wetering, M.8
Clevers, H.9
Saftig, P.10
-
41
-
-
0036208832
-
Patterns of linkage disequilibrium in the human genome
-
Ardlie, K.G., Kruglyak, L. and Seielstad, M. (2002) Patterns of linkage disequilibrium in the human genome. Nat. Rev. Genet., 3, 299-309.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 299-309
-
-
Ardlie, K.G.1
Kruglyak, L.2
Seielstad, M.3
-
42
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
Daly, M.J., Rioux, J.D., Schaffner, S.F., Hudson, T.J. and Lander, E.S. (2001) High-resolution haplotype structure in the human genome. Nat. Genet., 29, 229-232.
-
(2001)
Nat. Genet.
, vol.29
, pp. 229-232
-
-
Daly, M.J.1
Rioux, J.D.2
Schaffner, S.F.3
Hudson, T.J.4
Lander, E.S.5
-
43
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel, S.B., Schaffner, S.F., Nguyen, H., Moore, J.M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M. et al. (2002) The structure of haplotype blocks in the human genome. Science, 296, 2225-2229.
-
(2002)
Science
, vol.296
, pp. 2225-2229
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
Moore, J.M.4
Roy, J.5
Blumenstiel, B.6
Higgins, J.7
DeFelice, M.8
Lochner, A.9
Faggart, M.10
-
44
-
-
0035941029
-
Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21
-
Patil, N., Berno, A.J., Hinds, D.A., Barrett, W.A., Doshi, J.M., Hacker, C.R., Kautzer, C.R., Lee, D.H., Marjoribanks, C., McDonough, D.P. et al. (2001) Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science, 294, 1719-1723.
-
(2001)
Science
, vol.294
, pp. 1719-1723
-
-
Patil, N.1
Berno, A.J.2
Hinds, D.A.3
Barrett, W.A.4
Doshi, J.M.5
Hacker, C.R.6
Kautzer, C.R.7
Lee, D.H.8
Marjoribanks, C.9
McDonough, D.P.10
-
45
-
-
0034785352
-
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
-
Rioux, J.D., Daly, M.J., Silverberg, M.S., Lindblad, K., Steinhart, H., Cohen, Z., Delmonte, T., Kochner, K., Miller, K., Guschwan, S. et al. (2001) Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat. Genet., 29, 223-228.
-
(2001)
Nat. Genet.
, vol.29
, pp. 223-228
-
-
Rioux, J.D.1
Daly, M.J.2
Silverberg, M.S.3
Lindblad, K.4
Steinhart, H.5
Cohen, Z.6
Delmonte, T.7
Kochner, K.8
Miller, K.9
Guschwan, S.10
-
46
-
-
0029945706
-
Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker-sharing statistics
-
Sobel, E. and Lange, K. (1996) Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am. J. Hum. Genet., 58, 1323-1337.
-
(1996)
Am. J. Hum. Genet.
, vol.58
, pp. 1323-1337
-
-
Sobel, E.1
Lange, K.2
-
47
-
-
0035741831
-
Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees
-
Sobel, E., Sengul, H. and Weeks, D.E. (2001) Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum. Hered., 52, 121-131.
-
(2001)
Hum. Hered.
, vol.52
, pp. 121-131
-
-
Sobel, E.1
Sengul, H.2
Weeks, D.E.3
-
48
-
-
0008569127
-
Inheritance of multiple loci in familial Alzheimer disease
-
Corain, B., Iqbal, K., Nicolini, M., Winblad, B., Wisniewski, H. and Zatta, P. (eds), John Wiley and Sons, New York
-
Haines, J.L., St George-Hyslop, P.H., Rimmler, J.B., Yamaoka, L.H., Kazantsev, A., Tanzi, R.E., Gusella, J.F., Roses, A.D. and Pericak-Vance, M.A. (1993) Inheritance of multiple loci in familial Alzheimer disease. In Corain, B., Iqbal, K., Nicolini, M., Winblad, B., Wisniewski, H. and Zatta, P. (eds), Alzheimer's Disease: Advances in Clinical and Basic Research. John Wiley and Sons, New York, pp. 221-226.
-
(1993)
Alzheimer's Disease: Advances in Clinical and Basic Research
, pp. 221-226
-
-
Haines, J.L.1
St George-Hyslop, P.H.2
Rimmler, J.B.3
Yamaoka, L.H.4
Kazantsev, A.5
Tanzi, R.E.6
Gusella, J.F.7
Roses, A.D.8
Pericak-Vance, M.A.9
-
49
-
-
0033913161
-
Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: Potential genetic and phenotypic heterogeneity
-
Scott, W.K., Grubber, J.M., Conneally, P.M., Small, G.W., Hulette, C.M., Rosenberg, C.K., Saunders, A.M., Roses, A.D., Haines, J.L. and Pericak-Vance, M.A. (2000) Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. Am. J. Hum. Genet., 66, 922-932.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 922-932
-
-
Scott, W.K.1
Grubber, J.M.2
Conneally, P.M.3
Small, G.W.4
Hulette, C.M.5
Rosenberg, C.K.6
Saunders, A.M.7
Roses, A.D.8
Haines, J.L.9
Pericak-Vance, M.A.10
-
50
-
-
0003555521
-
-
2.0 edn. Population Genetics Laboratory Department of Genetics Southwest Foundation for Biomedical Research, San Antonio, TX
-
Dyke, B. and Mamelka, P. (1996) PEDSYS: a pedigree data management system, 2.0 edn. Population Genetics Laboratory Department of Genetics Southwest Foundation for Biomedical Research, San Antonio, TX.
-
(1996)
PEDSYS: A Pedigree Data Management System
-
-
Dyke, B.1
Mamelka, P.2
-
51
-
-
0032231877
-
Comprehensive human genetic maps: Individual and sex-specific variation in recombination
-
Broman, K.W., Murray, J.C., Sheffield, V.C., White, R.L. and Weber, J.L. (1998) Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am. J. Hum. Genet., 63, 861-869.
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 861-869
-
-
Broman, K.W.1
Murray, J.C.2
Sheffield, V.C.3
White, R.L.4
Weber, J.L.5
-
52
-
-
0000803318
-
Construction of multilocus genetic linkage maps in humans
-
Lander, E. and Green, P. (1987) Construction of multilocus genetic linkage maps in humans Proc. Nat. Acad. Sci. USA, 84, 2363-2367.
-
(1987)
Proc. Nat. Acad. Sci. USA
, vol.84
, pp. 2363-2367
-
-
Lander, E.1
Green, P.2
-
53
-
-
0031966959
-
Multipoint quantitative-trait linkage analysis in general pedigrees
-
Almasy, L. and Blangero, J. (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am. J. Hum. Genet., 62, 1198-1211.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 1198-1211
-
-
Almasy, L.1
Blangero, J.2
-
54
-
-
0003958977
-
SOLAR: Sequential oligogenic linkage analysis routines
-
Population Genetics Laboratory, Southwest Foundation for Biomedical Research, San Antonio, TX 78228
-
Blangero, J. and Almasy, L. (1996) SOLAR: sequential oligogenic linkage analysis routines. Population Genetics Laboratory, Southwest Foundation for Biomedical Research, San Antonio, TX 78228.
-
(1996)
-
-
Blangero, J.1
Almasy, L.2
-
55
-
-
0035084599
-
Exposure to Schistosoma mansoni infection in a rural area in Brazil. II: Household risk factors
-
Bethony, J., Williams, J.T., Kloos, H., Blangero, J., Alves-Fraga, L., Buck, G., Michalek, A., Williams-Blangero, S., Loverde, P.T., Correa-Oliveira, R. et al. (2001) Exposure to Schistosoma mansoni infection in a rural area in Brazil. II: household risk factors. Trop. Med. Int. Health, 6, 136-145.
-
(2001)
Trop. Med. Int. Health
, vol.6
, pp. 136-145
-
-
Bethony, J.1
Williams, J.T.2
Kloos, H.3
Blangero, J.4
Alves-Fraga, L.5
Buck, G.6
Michalek, A.7
Williams-Blangero, S.8
Loverde, P.T.9
Correa-Oliveira, R.10
-
56
-
-
0019920786
-
Extensions to multivariate normal models for pedigree analysis
-
Hopper, J.L. and Mathews, J.D. (1982) Extensions to multivariate normal models for pedigree analysis. Ann. Hum. Genet., 46, 373-383.
-
(1982)
Ann. Hum. Genet.
, vol.46
, pp. 373-383
-
-
Hopper, J.L.1
Mathews, J.D.2
-
57
-
-
0022649864
-
The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods
-
Boerwinkle, E., Chakraborty, R. and Sing, C.F. (1986) The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Ann. Hum. Genet., 50, 181-194.
-
(1986)
Ann. Hum. Genet.
, vol.50
, pp. 181-194
-
-
Boerwinkle, E.1
Chakraborty, R.2
Sing, C.F.3
-
58
-
-
0034193350
-
Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis
-
Soria, J.M., Almasy, L., Souto, J.C., Tirado, I., Borell, M., Mateo, J., Slifer, S., Stone, W., Blangero, J. and Fontcuberta, J. (2000) Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis. Blood, 95, 2780-2785.
-
(2000)
Blood
, vol.95
, pp. 2780-2785
-
-
Soria, J.M.1
Almasy, L.2
Souto, J.C.3
Tirado, I.4
Borell, M.5
Mateo, J.6
Slifer, S.7
Stone, W.8
Blangero, J.9
Fontcuberta, J.10
-
59
-
-
18244384262
-
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease
-
Soria, J.M., Almasy, L., Souto, J.C., Bacq, D., Buil, A., Faure, A., Martinez-Marchan, E., Mateo, J., Borrell, M., Stone, W. et al. (2002) A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. Am. J. Hum. Genet., 70, 567-574.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 567-574
-
-
Soria, J.M.1
Almasy, L.2
Souto, J.C.3
Bacq, D.4
Buil, A.5
Faure, A.6
Martinez-Marchan, E.7
Mateo, J.8
Borrell, M.9
Stone, W.10
-
60
-
-
0034017850
-
GOLD - Graphical overview of linkage disequilibrium
-
Abecasis, G.R. and Cookson, W.O. (2000) GOLD - graphical overview of linkage disequilibrium. Bioinformatics, 16, 182-183.
-
(2000)
Bioinformatics
, vol.16
, pp. 182-183
-
-
Abecasis, G.R.1
Cookson, W.O.2
-
61
-
-
0029130796
-
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier, L. and Slatkin, M. (1995) Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol. Biol. Evol., 12, 921-927.
-
(1995)
Mol. Biol. Evol.
, vol.12
, pp. 921-927
-
-
Excoffier, L.1
Slatkin, M.2
-
62
-
-
0000951097
-
The evolutionary dynamics of complex polymorphisms
-
Lewontin, R.C. and Kojima, K. (1960) The evolutionary dynamics of complex polymorphisms. Evolution, 14, 450-472.
-
(1960)
Evolution
, vol.14
, pp. 450-472
-
-
Lewontin, R.C.1
Kojima, K.2
|